Research Topics
Genomes and Genes | Daniela JezovaSummaryAffiliation: Slovak Academy of Sciences Country: Slovakia Publications
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Publications
Reduction of rise in blood pressure and cortisol release during stress by Ginkgo biloba extract (EGb 761) in healthy volunteersD Jezova
Laboratory of Pharmacological Neuroendocrinology, Slovak Academy of Sciences, Bratislava
J Physiol Pharmacol 53:337-48. 2002..Thus, this study provides evidence that EGb 761 has an inhibitory action on blood pressure and it may influence cortisol release in response to some stress stimuli...- Hypothalamo-pituitary-adrenocortical axis function and hedonic behavior in adult male and female rats prenatally stressed by maternal food restrictionD Jezova
Laboratory of Pharmacological Neuroendocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Solvak Republic
Stress 5:177-83. 2002..These data together with observed changes in hormone and CRH mRNA levels indicate that the gestational stress used did not result in a depression-like state in adult offspring... - Growth hormone response to different consecutive stress stimuli in healthy men: is there any difference?D Jezova
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Vlarska 3, 83306 Bratislava, Slovakia
Stress 10:205-11. 2007..Unlike in the case of exercise and hyperthermia, mechanisms involved in the stress response to hypoglycemia appear to overcome the usual feedback mechanisms and to re-induce the GH response when applied after another stimulus... - Control of ACTH secretion by excitatory amino acids: functional significance and clinical implicationsDaniela Jezova
Laboratory of Pharmacological Neuroendocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Vlarska 3, Bratislava 83306, Slovakia
Endocrine 28:287-94. 2005..Nevertheless, pharmacological interventions influencing interaction between glutamate and the HPA axis are promising treatment possibilities in psychiatry and neurology... - Subchronic treatment with amino acid mixture of L-lysine and L-arginine modifies neuroendocrine activation during psychosocial stress in subjects with high trait anxietyDaniela Jezova
Laboratory of Pharmacological Neuroendocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia
Nutr Neurosci 8:155-60. 2005..Such action may represent a normalization of hormone levels to the pattern observed previously in subjects with low trait anxiety... - High trait anxiety in healthy subjects is associated with low neuroendocrine activity during psychosocial stressDaniela Jezova
Laboratory of Pharmacological Neuroendocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Vlarska 3, Bratislava 83306, Slovakia
Prog Neuropsychopharmacol Biol Psychiatry 28:1331-6. 2004..Our findings suggest that high trait anxiety may be associated with an inability to respond with adequate hormone release to acute stress stimuli... - Behavioral sensitization to intermittent morphine in mice is accompanied by reduced adrenocorticotropine but not corticosterone responsesDaniela Jezova
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia
Brain Res 1021:63-8. 2004..Intermittent administration of morphine for 2 weeks failed to induce marked signs of glucocorticoid overexposure... - Stress-induced rise in endothelaemia, von Willebrand factor and hypothalamic-pituitary-adrenocortical axis activation is reduced by pretreatment with pentoxifyllineD Jezova
Laboratory of Pharmacological Neuroendocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia
J Physiol Pharmacol 54:329-38. 2003..This protective action of pentoxifylline might be of benefit in the prevention and therapy of some stress-related disorders... - Modulation of neuroendocrine response and non-verbal behavior during psychosocial stress in healthy volunteers by the glutamate release-inhibiting drug lamotrigineAikaterini Makatsori
Laboratory of Pharmacological Neuroendocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia
Neuroendocrinology 79:34-42. 2004..The effects on plasma renin activity and aldosterone release observed seem to be related to other actions of lamotrigine... - Repeated citalopram treatment but not stress exposure attenuates hypothalamic-pituitary-adrenocortical axis response to acute citalopram injectionFedor Moncek
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Vlarska 3, 83306 Bratislava, Slovakia
Life Sci 72:1353-65. 2003..Repeated administration of the drug led to the development of tolerance to activation of central and peripheral components of HPA axis, but not to serotonin reuptake inhibition... 
Eplerenone, a selective mineralocorticoid receptor blocker, exerts anxiolytic effects accompanied by changes in stress hormone releaseNatasa Hlavacova
Laboratory of Pharmacological Neuroendocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia
J Psychopharmacol 24:779-86. 2010..In conclusions, chronic treatment with eplerenone (1) exerts anxiolytic effects and (2) influences corticosterone, oxytocin and vasopressin concentrations in a manner consistent with the anxiolytic outcome...- Chronic treatment with the mineralocorticoid hormone aldosterone results in increased anxiety-like behaviorNatasa Hlavacova
Laboratory of Pharmacological Neuroendocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Vlarska 3, Bratislava, Slovakia
Horm Behav 54:90-7. 2008..The results provide evidence on anxiogenic action of prolonged increase in circulating aldosterone concentrations. Thus, aldosterone may represent an important target for future antidepressant and anxiolytic drug development... - Insufficient activation of adrenocortical but not adrenomedullary hormones during stress in rats subjected to repeated immune challengeFedor Moncek
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Vlarska 3, 83306 Bratislava, Slovakia
J Neuroimmunol 142:86-92. 2003..These alterations may contribute to the development of cardiovascular complications during chronic inflammatory states... - Endocrine factors in stress and psychiatric disorders: focus on anxiety and salivary steroidsDaniela Jezova
Institute of Experimental Endocrinology, Laboratory of Pharmacological Neuroendocrinology, Slovak Academy of Sciences, Bratislava, Slovakia
Ann N Y Acad Sci 1148:495-503. 2008..A more proper elucidation of the association between aldosterone and anxiety seems to be an important target of further research... - Attenuated neuroendocrine response to hypoglycemic stress in patients with panic disorderDaniela Jezova
Laboratory of Pharmacological Neuroendocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia daniela jezova savba sk
Neuroendocrinology 92:112-9. 2010..The aim of this study was to test the hypothesis that neuroendocrine activation during hypoglycemic stress is altered in panic disorder patients compared to healthy subjects... - Neuroendocrine activation during combined mental and physical stress in women depends on trait anxiety and the phase of the menstrual cycleNatasa Hlavacova
Institute of Experimental Endocrinology, Laboratory of Pharmacological Neuroendocrinology, Slovak Academy of Sciences, Bratislava, Slovakia
Ann N Y Acad Sci 1148:520-5. 2008..The results suggest that women with high trait anxiety exhibit greater cardiovascular and hormonal sensitivity to stress stimuli during the follicular phase... - Effect of single treatment with the antihypertensive drug eplerenone on hormone levels and anxiety-like behaviour in ratsNatasa Hlavacova
Laboratory of Pharmacological Neuroendocrinology, Institute of Experiemental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia
Endocr Regul 42:147-53. 2008..the hypothalamic-pituitary-adrenocortical (HPA) axis; 2. the renin-angiotensin-aldosterone (RAA) system, 3. anxiety-like behaviour... - Differences in home cage behavior and endocrine parametres in rats of four strainsNatasa Hlavacova
Institute of Experimental Endocrinology, Laboratory of Pharmacological Neuroendocrinology, Slovak Academy of Sciences, 833 06 Bratislava, Slovakia
Endocr Regul 40:113-8. 2006..The aim of the present study was to compare home cage behavior and basal hormone levels in two outbred rat strains, Sprague-Dawley (SD) and Wistar as well as two inbred strains, Lewis and Spontaneously Hypertensive Rats (SHR)... - Altered coordination of the neuroendocrine response during psychosocial stress in subjects with high trait anxietyRoman Duncko
Laboratory of Pharmacological Neuroendocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Vlarska 3, 83306 Bratislava, Slovakia
Prog Neuropsychopharmacol Biol Psychiatry 30:1058-66. 2006..Our findings indicate that subjects with high anxiety have different relationships between specific neuroendocrine parameters, subjective perception of stress and Stroop test performance... - Subchronic treatment with aldosterone induces depression-like behaviours and gene expression changes relevant to major depressive disorderNatasa Hlavacova
Laboratory of Pharmacological Neuroendocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Vlarska, Bratislava, Slovakia
Int J Neuropsychopharmacol 15:247-65. 2012..Subchronic treatment with aldosterone represents a new animal model of depression, which may contribute to the development of novel targets for the treatment of depression... - Phenylethanolamine N-methyltransferase gene expression in the heart and blood pressure response to oxytocin treatment in rats exposed to voluntary wheel runningJan Bakos
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia
Ann N Y Acad Sci 1148:302-7. 2008..In conclusion, voluntary wheel running failed to modify sensitivity to cardiovascular action of oxytocin but resulted in increased gene expression of PNMT in left, but not right, heart atrium in a running activity-dependent manner... - Activation of FOS in hypocretin neurons of the rat by insulin-induced hypoglycemiaAlexander Kiss
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Vlarska 3, 833 06 Bratislava, Slovak Republic
Endocr Regul 38:97-102. 2004..In addition, there was also an attempt to depict the spatial organization of activated HCRT perikarya within the whole portion of the medial and lateral hypothalamic (LHA) areas... - Enhancement of stress-induced pituitary hormone release and cardiovascular activation by antidepressant treatment in healthy menDaniela Jezova
Laboratory of Pharmacological Neuroendocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava
J Psychopharmacol 16:235-40. 2002.... - Prenatal immune challenge affects growth, behavior, and brain dopamine in offspringJan Bakos
Laboratory of Pharmacological Neuroendocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Vlarska 3, 833 06, Bratislava, Slovakia
Ann N Y Acad Sci 1018:281-7. 2004..Thus, immune activation during pregnancy may induce long-term changes in brain catecholamines and behavior, but it is not harmful to basal hormone secretion in the offspring... - Effect of chronic emotional stress on habituation processes in open field in adult ratsMichal Dubovicky
Institute of Experimental Pharmacology, Slovak Academy of Sciences, Dubravska cesta 9, 841 04 Bratislava, Slovakia
Ann N Y Acad Sci 1018:199-206. 2004..The results suggest that, in contrast to neonatal stress exposure, chronic emotional stress in adult rats does not represent a risk factor for the alteration of habituation processes... - Changes in retinoic acid receptor status, 5'-deiodinase activity and neuroendocrine response to voluntary wheel runningSlavomira Ondkova
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Vlarska 3, Bratislava 83306, Slovak Republic
Gen Comp Endocrinol 165:304-8. 2010..Neuroendocrine mechanisms involved in these changes may include adrenal mineralo- and glucocorticoids... - Enriched environment influences adrenocortical response to immune challenge and glutamate receptor gene expression in rat hippocampusMartin Mlynarik
Laboratory of Pharmacological Neuroendocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Vlarska 3, Bratislava 833 06, Slovakia
Ann N Y Acad Sci 1018:273-80. 2004..The fact that differences in housing conditions change stress response has to be considered in biomedical research... - Altered glutamate receptor and corticoliberin gene expression in brain regions related to hedonic behavior in ratsRoman Duncko
Laboratory of Pharmacological Neuroendocrinology, Institute of Experimental Endocrinology, Slovak Academy of Sciences, , Bratislava 83306, Slovakia
Pharmacol Biochem Behav 76:9-16. 2003..These mechanisms may operate in the disposition to develop hedonic deficit in some mental disorders... - Prolonged oxytocin treatment in rats affects intracellular signaling and induces myocardial protection against infarctionMaria Ondrejcakova
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovak Republic
Gen Physiol Biophys 31:261-70. 2012..The present results show that positive effects of oxytocin that may ameliorate negative consequences of stress on the heart are, at least in part, mediated through p38-MAPK and Akt kinase pathways... - Oxytocin exerts protective effects on in vitro myocardial injury induced by ischemia and reperfusionMaria Ondrejcakova
Institute of Heart Research, Department of Cardiovascular Physiology and Pathophysiology, Slovak Academy of Sciences, Bratislava 84005, Slovakia
Can J Physiol Pharmacol 87:137-42. 2009..The data suggest that the negative chronotropic action of oxytocin participates in its protective effects on ischemia-reperfusion-induced myocardial injury... 
Subchronic treatment of rats with oxytocin results in improved adipocyte differentiation and increased gene expression of factors involved in adipogenesisMiroslava Eckertova
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia
Br J Pharmacol 162:452-63. 2011....- Head down tilt at -6 degrees to -24 degrees can neutralize the cardiovascular effects of LBNP at -15 or -35 mmHgHelmut Hinghofer-Szalkay
Institute for Adaptive and Spaceflight Physiology, Graz, Austria
Aviat Space Environ Med 75:947-51. 2004.... - Adrenomedullin and elements of orthostatic competence after 41 h of voluntary submersion in water as measured in four healthy malesIngrid Loder
Institute of Adaptive and Spaceflight Physiology, Wormgasse 9, 8010 Graz, Austria
Eur J Appl Physiol 96:644-50. 2006..Circadian cortisol rhythm seems to be conserved even under extreme circumstances as those of this study... - Different effects of novel stressors on sympathoadrenal system activation in rats exposed to long-term immobilizationSladjana Dronjak
Institute of Vinca, Belgrade, Serbia and Montenegro, P O Box 522 090, 11001 Belgrade
Ann N Y Acad Sci 1018:113-23. 2004..Reduced plasma CA levels in long-term immobilized rats exposed to homotypic stressor are most probably due to an adaptation at the level of brain regulatory centers... - Bed rest immobilization with various oral sodium supply: plasma hormones and body fluidsHelmut G Hinghofer-Szalkay
Institute for Adaptive Spaceflight Physiology, Graz, Austria
Endocr Regul 36:151-9. 2002.... - Low- versus high-baseline epinephrine output shapes opposite innate cytokine profiles: presence of Lewis- and Fischer-like neurohormonal immune phenotypes in humans?Ilia J Elenkov
Arthritis and Rheumatism Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA
J Immunol 181:1737-45. 2008.... - Sodium intake does not influence bioimpedance-derived extracellular volume loss in head-down restHelmut G Hinghofer-Szalkay
Institute for Adaptive and Spaceflight Physiology, Graz, Austria
Aviat Space Environ Med 75:1036-41. 2004..The primary purpose of this study was to assess the effects of salt intake on extracellular volume (ECV) during HDBR... - Stress symptoms induced by repeated morphine withdrawal in comparison to other chronic stress models in miceDora Zelena
Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
Neuroendocrinology 81:205-15. 2005..The most severe chronic stress state developed in mice during untreated STZ-DM. Thus, naloxone-precipitated withdrawal in mice seems to be an appropriate model of chronic stress...