Research Topics
Species | M DusinskaSummaryAffiliation: Institute of Preventive and Clinical Medicine Country: Slovakia Publications
| Collaborators
|
Detail Information
Publications
Nutritional supplementation with antioxidants decreases chromosomal damage in humansM Dusinska
Institute of Preventive and Clinical Medicine, Limbova 14, 83301 Bratislava, Slovak Republic
Mutagenesis 18:371-6. 2003..The largest effect of supplementation was seen in smokers in this group (0.12% aberrant cells in supplemented compared with 0.81% in placebo group; P > 0.001). The results support the hypothesis that antioxidants decrease genetic damage...
Responses of alveolar macrophages and epithelial type II cells to oxidative DNA damage caused by paraquatM Dusinska
Institute of Preventive and Clinical Medicine, Bratislava, Slovak Republic
Carcinogenesis 19:809-12. 1998..The relatively high level of endogenous damage in pneumocytes suggests that these cells are inefficient at DNA repair, which would be consistent with their probable role as the principal progenitors of lung cancer...
The effect of fibrous dusts on lung cells. In vitro studyZ Kovacikova
Slovak Medical University, Institute of Preventive and Clinical Medicine, Bratislava, Slovak Republic
Cent Eur J Public Health 12:S44-8. 2004..Transmission electron microscopy showed that already 1 microg x cm(-2) amosite caused destruction of AM while other fibres were phagocytized...
Glutathione S-transferase polymorphisms influence the level of oxidative DNA damage and antioxidant protection in humansM Dusinska
Department of Molecular and Genetic Toxicology, Institute of Preventive and Clinical Medicine, Limbova 14, 83301 Bratislava, Slovak Republic
Mutat Res 482:47-55. 2001..It seems that polymorphisms in the phase II metabolising enzyme glutathione S-transferase may be important determinants of commonly measured biomarkers...
Some lung cellular parameters reflecting inflammation after combined inhalation of amosite dust with cigarette smoke by ratsM Beno
Slovak Medical University, Institute of Preventive and Clinical Medicine, Bratislava, Slovak Republic
Cent Eur J Public Health 12:S11-3. 2004..It is concluded that, in the experimental assessment of effects of fibrogenic dusts, the number of BNC and of MNC in lung cell suspensions may serve as a useful semiquantitative biomarker of the inflammation...
Lipid peroxidation in relation to vitamin C and vitamin E levelsM Krajcovicova-Kudlackova
Slovak Health University, Institute of Preventive and Clinical Medicine, Bratislava, Slovak Republic
Cent Eur J Public Health 12:46-8. 2004..The results document that the deficiency in two key antioxidants for lipid peroxidation inhibition means the insufficient defense against free radicals and the increased lipid peroxidation...
Lipid peroxidation in men after dietary supplementation with a mixture of antioxidant nutrientsA Nagyova
Research Base, Slovak Medical University, Institute of Preventive and Clinical Medicine, Bratislava, Slovakia
Bratisl Lek Listy 105:277-80. 2004..Since a more pronounced effect was observed within the group of survivors of myocardial infarction, a recommendation of antioxidant supplements seems appropriate for patients with a history of cardiovascular disease. (Fig. 1, Ref. 19.)..
DNA damage of lymphocytes in experimental chronic renal failure: beneficial effects of losartanZ Krivosikova
Department of Pharmacotherapy, and Institutes of Preventive and Clinical Medicine, Hospital of the Ministry of Defense, Bratislava, Slovak Republic
Kidney Int Suppl 78:S212-5. 2001..One of them could be the impairment of DNA stability with the increased formation of DNA breaks...
Effects of occupational exposure to styrene on expression of adhesion molecule on leukocytesE Jahnova
Institute of Preventive and Clinical Medicine, Bratislava, Slovak Republic
Hum Exp Toxicol 21:235-40. 2002..Styrene exposure appears to increase activation of the immune system and alter leukocyte adherence. This interaction is a critical first step in immune stimulation and leukocyte-endothelial interaction...
Oxidative DNA damage in relation to nutritionM Krajcovicova-Kudlackova
Institute of Preventive and Clinical Medicine, Bratislava, 833 01 Slovak Republic
Neoplasma 51:30-3. 2004..The results of reduced endogenous DNA damage and higher antioxidative status in vegetarians document that a correct vegetarian nutrition might represent an effective cancer prevention...
Ciprofibrate treatment in patients with atherogenic lipoprotein phenotype: effects on HDL quality, LDL susceptibility to oxidation and DNA damageK Raslova
Institute of Preventive and Clinical Medicine, Bratislava, Slovak Republic
Eur J Clin Pharmacol 54:697-9. 1998..This study was conducted to examine a complex effect of ciprofibrate therapy in patients with atherogenic lipoprotein phenotype...
Apolipoprotein E genotypes in offspring with a positive and negative family history of premature myocardial infarctionK Raslova
Institute of Preventive and Clinical Medicine, Bratislava, Slovak Republic
Clin Genet 53:387-90. 1998....
Changes in cellular immunity among workers occupationally exposed to styrene in a plastics lamination plantJ Tulinska
Institute of Preventive and Clinical Medicine, Department of Immunotoxicology, Limbova 14, 833 01 Bratislava, Slovak Republic
Am J Ind Med 38:576-83. 2000..5 mg/m(3). Mean concentration of styrene in the blood of exposed workers was 945.7 microg/L and the mean styrene in exhaled air was 38.8 microg/L...
Polyunsaturated Fatty Acid Plasma Content in Groups of General Population with lowvitamin B6 or low iron serum levelsM Krajcovicova-Kudlackova
Institute of Preventive and Clinical Medicine, Bratislava, Slovak Republic
Ann Nutr Metab 48:118-21. 2004..The inhibition effect on fatty acid synthesis was more pronounced in subjects with low iron levels than in those with low vitamin B6 levels. The conversion indices correlated significantly positively with vitamin B6 or iron levels...
