G Slobodin

Summary

Publications

  1. pmc The emergency room in systemic rheumatic diseases
    G Slobodin
    Department of Internal Medicine A, Bnai Zion Medical Center, Haifa 31048, PO Box 4940, Israel
    Emerg Med J 23:667-71. 2006
  2. ncbi request reprint Chronic pain of aortitis: an underestimated clinical sign?
    Gleb Slobodin
    Joint Bone Spine 75:96-8. 2008
  3. doi request reprint Higher expression of latency-associated peptide on the surface of peripheral blood monocytes in patients with rheumatoid arthritis may be protective against articular erosions
    Gleb Slobodin
    Internal Medicine A, Bnai Zion Medical Center, P O Box 4940, Haifa, 31048, Israel
    Inflammation 36:1075-8. 2013
  4. doi request reprint Incidental computed tomography sacroiliitis: clinical significance and inappropriateness of the New York radiological grading criteria for the diagnosis
    Gleb Slobodin
    Internal Medicine A, Bnai Zion Medical Center, P O Box 4940, Haifa 31048, Israel
    Clin Rheumatol 31:425-8. 2012
  5. doi request reprint Phenotype of resting and activated monocyte-derived dendritic cells grown from peripheral blood of patients with ankylosing spondylitis
    Gleb Slobodin
    Internal Medicine A, Bnai Zion Medical Center, Haifa 31048, P O Box 4940, Israel
    Inflammation 35:772-5. 2012
  6. ncbi request reprint Varied presentations of enthesopathy
    Gleb Slobodin
    Department of Internal Medicine A, Bnai Zion Medical Center and Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel
    Semin Arthritis Rheum 37:119-26. 2007
  7. doi request reprint Endothelin-1 does not change the function of monocyte-derived dendritic cells grown from patients with systemic sclerosis
    Gleb Slobodin
    Department of Internal Medicine, Bnai Zion Medical Center and Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel
    Immunol Invest 37:841-8. 2008
  8. doi request reprint Etanercept impairs maturation of human monocyte-derived dendritic cells by inhibiting the autocrine TNFalpha-mediated signaling
    Gleb Slobodin
    Department of Internal Medicine A, Bnai Zion Medical Center, Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel
    Inflammation 32:146-50. 2009
  9. doi request reprint Pamidronate treatment in rheumatology practice: a comprehensive review
    Gleb Slobodin
    Department of Internal Medicine A, Bnai Zion Medical Center and Ruth and Bruce Rappaport Faculty of Medicine, Technion, 47, Golomb St, Haifa 31048, Israel
    Clin Rheumatol 28:1359-64. 2009
  10. doi request reprint Regulatory T cells (CD4(+)CD25(bright)FoxP3(+)) expansion in systemic sclerosis correlates with disease activity and severity
    Gleb Slobodin
    Department of Internal Medicine A, Bnai Zion Medical Center and Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel
    Cell Immunol 261:77-80. 2010

Detail Information

Publications35

  1. pmc The emergency room in systemic rheumatic diseases
    G Slobodin
    Department of Internal Medicine A, Bnai Zion Medical Center, Haifa 31048, PO Box 4940, Israel
    Emerg Med J 23:667-71. 2006
    ..This review is written for the emergency room physician and discusses the early recognition of selected emergencies in the context of a defined rheumatic disease...
  2. ncbi request reprint Chronic pain of aortitis: an underestimated clinical sign?
    Gleb Slobodin
    Joint Bone Spine 75:96-8. 2008
  3. doi request reprint Higher expression of latency-associated peptide on the surface of peripheral blood monocytes in patients with rheumatoid arthritis may be protective against articular erosions
    Gleb Slobodin
    Internal Medicine A, Bnai Zion Medical Center, P O Box 4940, Haifa, 31048, Israel
    Inflammation 36:1075-8. 2013
    ..Higher expression of LAP on the surface of the cells of monocyte lineage may be protective of formation of articular erosions in RA. Further studies are needed to elaborate the mechanism of this phenomenon...
  4. doi request reprint Incidental computed tomography sacroiliitis: clinical significance and inappropriateness of the New York radiological grading criteria for the diagnosis
    Gleb Slobodin
    Internal Medicine A, Bnai Zion Medical Center, P O Box 4940, Haifa 31048, Israel
    Clin Rheumatol 31:425-8. 2012
    ..CT noted erosions of the SIJ appear to be a reliable diagnostic sign of sacroiliitis, while the significance of the osseous sclerosis, seen on CT adjacent to SIJs requires better understanding...
  5. doi request reprint Phenotype of resting and activated monocyte-derived dendritic cells grown from peripheral blood of patients with ankylosing spondylitis
    Gleb Slobodin
    Internal Medicine A, Bnai Zion Medical Center, Haifa 31048, P O Box 4940, Israel
    Inflammation 35:772-5. 2012
    ..Functional studies on DCs from patients with AS are needed to evaluate the integrity of their antigen-presenting function...
  6. ncbi request reprint Varied presentations of enthesopathy
    Gleb Slobodin
    Department of Internal Medicine A, Bnai Zion Medical Center and Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel
    Semin Arthritis Rheum 37:119-26. 2007
    ..The concept of "enthesis organ" allows a new look at the nature of enthesis involvement in some rheumatic and nonrheumatic systemic disorders...
  7. doi request reprint Endothelin-1 does not change the function of monocyte-derived dendritic cells grown from patients with systemic sclerosis
    Gleb Slobodin
    Department of Internal Medicine, Bnai Zion Medical Center and Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel
    Immunol Invest 37:841-8. 2008
    ..The examined function of MDDCs from SSc patients and healthy volunteers did not differ under these conditions and was not dependent on the presence of ET-1...
  8. doi request reprint Etanercept impairs maturation of human monocyte-derived dendritic cells by inhibiting the autocrine TNFalpha-mediated signaling
    Gleb Slobodin
    Department of Internal Medicine A, Bnai Zion Medical Center, Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel
    Inflammation 32:146-50. 2009
    ..The data also suggests the presence of TNFalpha-mediated autocrine signaling, serving to accelerate or catalyze the maturation process of MDDCs...
  9. doi request reprint Pamidronate treatment in rheumatology practice: a comprehensive review
    Gleb Slobodin
    Department of Internal Medicine A, Bnai Zion Medical Center and Ruth and Bruce Rappaport Faculty of Medicine, Technion, 47, Golomb St, Haifa 31048, Israel
    Clin Rheumatol 28:1359-64. 2009
    ..Large randomized, controlled studies examining the efficacy of pamidronate in the rheumatic conditions are urgently needed...
  10. doi request reprint Regulatory T cells (CD4(+)CD25(bright)FoxP3(+)) expansion in systemic sclerosis correlates with disease activity and severity
    Gleb Slobodin
    Department of Internal Medicine A, Bnai Zion Medical Center and Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel
    Cell Immunol 261:77-80. 2010
    ..The role and function of T regulatory (Treg) cells have not been fully investigated in patients with systemic sclerosis (SSc)...
  11. doi request reprint The synergistic efficacy of adalimumab and pamidronate in a patient with ankylosing spondylitis
    Gleb Slobodin
    Department of Internal Medicine A, Bnai Zion Medical Center, Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, 31048, PO Box 4940, Israel
    Clin Rheumatol 29:793-4. 2010
    ..Complete disappearance of the back pain was reported after the second pamidronate infusion. The perspectives of the combination therapy with TNF-alpha inhibitor and pamidronate are discussed...
  12. doi request reprint Recently diagnosed axial spondyloarthritis: gender differences and factors related to delay in diagnosis
    Gleb Slobodin
    Internal Medicine A, Bnai Zion Medical Center, Haifa, Israel
    Clin Rheumatol 30:1075-80. 2011
    ..Presence of WP in women almost doubled the delay in the diagnosis of SpA. No other differences in disease presentation or burden were demonstrated to correlate with delay in diagnosis...
  13. ncbi request reprint LPS-stimulated production of TNF-alpha by peripheral blood monocytes in patients with Behcet's disease
    Gleb Slobodin
    Department of Internal Medicine A, Bnai Zion Medical Center, P O Box 4940, Technion, Haifa 31048, Israel
    Clin Rheumatol 26:764-7. 2007
    ..03). PBM of BD patients in the present study did not overproduce TNF-alpha upon stimulation with LPS. However, BD patients with a higher TNF-alpha-producing capacity had worse sense of well-being...
  14. ncbi request reprint Gottron's papules-like eruption developing under hydroxyurea therapy
    Gleb Slobodin
    Department of Internal Medicine A, Bnai Zion Medical Center, Haifa, 31048, PO Box 4940, Israel
    Rheumatol Int 26:768-70. 2006
    ..Skin biopsy was compatible with seborrheic keratosis. Conditions presenting with GP but unrelated to DM are reviewed, with emphasis on hydroxyurea-induced skin lesions...
  15. ncbi request reprint Aortic involvement in rheumatic diseases
    G Slobodin
    Department of Internal Medicine A, Bnai Zion Medical Center, Technion, Haifa, Israel
    Clin Exp Rheumatol 24:S41-7. 2006
    ..To review the prevalence, mechanisms, presentations and clinical significance of aortic involvement in rheumatic inflammatory diseases...
  16. ncbi request reprint Osteolysis with detritic synovitis: appearance in a patient with connective tissue disease
    Gleb Slobodin
    Bnai Zion Medical Center and Bruce Rapoport Faculty of Medicine, Technion, Haifa, Israel
    Arthritis Rheum 53:126-8. 2005
  17. ncbi request reprint Systemic sclerosis sine scleroderma: is it always the same disease? Report of three patients and discussion
    Gleb Slobodin
    Department of Internal Medicine A, Bnai Zion Medical Center and Bruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    Rheumatol Int 22:170-2. 2002
    ..By reporting three new cases and analyzing previously published data, we discuss possible subsets and variants of the disease form...
  18. pmc Changes in macrophage function after rituximab treatment in patients with rheumatoid arthritis
    E Toubi
    Division of Clinical Immunology and Allergy, Bnai Zion Medical Center, P O Box 4940, Haifa 31048, Israel
    Ann Rheum Dis 66:818-20. 2007
    ..To assess changes in macrophage phenotype and function after rituximab-induced B cell depletion in patients with rheumatoid arthritis (RA)...
  19. doi request reprint The role of regulatory T cells in familial Mediterranean fever (FMF)
    D Rimar
    Rheumatology Unit, Bnai Zion Medical Center, POB 4940, Haifa 31048, Israel
    Clin Rheumatol 31:885-8. 2012
    ..It is suggested that T-regs may have a role in terminating FMF attacks...
  20. ncbi request reprint Nonspecific dizziness: frequency of supine hypertension associated with hypotensive reactions on head-up tilt
    J E Naschitz
    Department of Internal Medicine A, the Bnai Zion Medical Center and Bruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    J Hum Hypertens 20:157-62. 2006
    ..Different patterns of SH-HRT on HUTT may reflect different aberrations in cardiovascular homeostasis and may require differentiated management strategies...
  21. ncbi request reprint Behcet disease in adult Druzes in north Israel: the influence of ethnic origin on disease expression and severity
    M Rozenbaum
    Rappaport Faculty of Medicine, Technion, Israel
    J Clin Rheumatol 13:124-7. 2007
    ..Behcet's disease (BD) is known to vary in severity and manifestations in different populations...
  22. pmc The patient with supine hypertension and orthostatic hypotension: a clinical dilemma
    J E Naschitz
    Department of Internal Medicine A, Bnai Zion Medical Center and Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    Postgrad Med J 82:246-53. 2006
    ..Discrete patterns of SH-OH may be recognisable. This review focuses on the management of the patient with coexistent SH-OH...
  23. ncbi request reprint Anti-IL-6 receptor antibody (tocilizumab): a B cell targeting therapy
    A Snir
    Division of Allergy and Clinical Immunology, Bnai Zion Medical Center, Faculty of Medicine, Technion, Haifa, Israel
    Clin Exp Rheumatol 29:697-700. 2011
    ..Tocilizumab, a recombinant humanised monoclonal antibody that acts as IL-6R antagonist has been recently introduced for the treatment of rheumatoid arthritis (RA)...
  24. ncbi request reprint Pseudopodagra: A presenting manifestation of infective endocarditis
    N Boulman
    Department of Rheumatology, Bnai Zion Medical Center, Haifa, Israel
    Clin Exp Rheumatol 23:251-3. 2005
    ..As in this case, the diagnosis of gout should rest on findings beyond the presence at 1st MTP arthritis, with evaluation of all extraarticular signs in order to rule out other possible diagnoses...
  25. ncbi request reprint Enhanced peripheral T-cell apoptosis in chronic hepatitis C virus infection: association with liver disease severity
    E Toubi
    Department of Internal Medicine, Bnai Zion Medical Center, Faculty of Medicine, Technion, 31048, Haifa, Israel
    J Hepatol 35:774-80. 2001
    ..In the present study we have investigated the role of bcl-2 and nuclear factor kappa B (NFkappaB) in dexamethasone-induced apoptosis of peripheral T cells in chronic HCV infection...
  26. ncbi request reprint Hyperventilation and amplified blood pressure response: is there a link?
    J E Naschitz
    Department of Internal Medicine A, Bnai Zion Medical Center, Haifa, Israel
    J Hum Hypertens 19:381-7. 2005
    ..95 mmHg (s.d. 5.7), comparable to the DBP-change in patients with HV. In, conclusion, posturally induced HV was not associated with an increase in BP, nor was PHT associated with HV, except in a small minority of cases...
  27. doi request reprint An open study of pamidronate in the treatment of refractory degenerative lumbar spinal stenosis
    Joy Feld
    Rheumatology Department, Bnai Zion Medical Center, Ruth and Bruce Rappaport Faculty of Medicine, Technion, P O Box 4940, Haifa, 31048, Israel
    Clin Rheumatol 28:715-7. 2009
    ..The results of this pilot trial suggest the usefulness of this modality and warrant examination in a controlled clinical trial...
  28. ncbi request reprint Catastrophic acro-osteolysis of hands in systemic sclerosis
    Michael Rozenbaum
    Department of Rheumatology, Bnai Zion Medical Center, Haifa, Israel
    J Clin Rheumatol 13:169-70. 2007
  29. ncbi request reprint Polyarthritis flare complicating rheumatoid arthritis infliximab therapy: a paradoxic adverse reaction
    Michael Rozenbaum
    Department of Rheumatology, Bnai Zion Medical Center, Haifa, Israel
    J Clin Rheumatol 12:269-71. 2006
    ..Although subsets of patients may have only partial or no response, there is no report yet on possible worsening of RA with this therapy...
  30. ncbi request reprint Quantitative liver-spleen scan using single photon emission computerized tomography (SPECT) for assessment of hepatic function in cirrhotic patients
    Eli Zuckerman
    Liver Unit, Department of Internal Medicine A, Bnai Zion Medical Center, 47 Golomb Street, P O Box 4940, Haifa 31048, Israel
    J Hepatol 39:326-32. 2003
    ..Thus, this study was conducted to evaluate quantitative single photon emission computerized tomography (SPECT) of Tc-99mm-phytate colloid uptake by the liver as a test for hepatic function in cirrhotic patients...
  31. doi request reprint Electrocardiographic QT interval and cardiovascular reactivity in fibromyalgia differ from chronic fatigue syndrome
    Jochanan E Naschitz
    Department of Internal Medicine A, Bnai Zion Medical Center and Rappaport Family Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    Eur J Intern Med 19:187-91. 2008
    ..We have recently shown that CFS is associated with a short corrected electrocardiographic QT interval (QTc). In the present study, we evaluated whether FM and CFS can be distinguished by QTc...
  32. ncbi request reprint Takayasu's arteritis as a cause of carotidynia: clinical and imaging features
    Abdel Rauf Zeina
    Department of Radiology and MAR Imaging Institute, Bnai Zion Medical Center, Haifa, Israel
    Isr Med Assoc J 10:158-9. 2008
  33. ncbi request reprint Calcinosis in rheumatic diseases
    Nina Boulman
    Department of Rheumatology, Bnai Zion Medical Center, Rappaport Faculty of Medicine, Technion, Haifa, Israel
    Semin Arthritis Rheum 34:805-12. 2005
    ..The calcinotic accumulations may lead secondarily to muscle atrophy, joint contractures, and skin ulceration complicated by recurrent episodes of local inflammation and infection...
  34. ncbi request reprint Dropped head: an unusual presentation of dermatomyositis
    Gleb Slobodin
    J Rheumatol 32:1174-5. 2005
  35. ncbi request reprint Giant cell arteritis--the methotrexate debate revisited
    Doron Rimar
    J Rheumatol 33:1458-9. 2006