Karen Sliwa

Summary

Publications

  1. ncbi request reprint Hypertension and hypertensive heart disease in African women
    Karen Sliwa
    Department of Medicine, Hatter Institute for Cardiovascular Research in Africa and IIDMM, Faculty of Health Sciences, Groote Schuur Hospital and University of Cape Town, Observatory, Cape Town, 7925, South Africa
    Clin Res Cardiol 103:515-23. 2014
  2. pmc The 12-lead ECG in peripartum cardiomyopathy
    Kemi Tibazarwa
    Hatter Institute for Cardiovascular Research in Africa, Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa
    Cardiovasc J Afr 23:322-9. 2012
  3. doi request reprint Redefining the ECG in urban South Africans: electrocardiographic findings in heart disease-free Africans
    Karen Sliwa
    Hatter Institute for Cardiovascular Research in Africa and IIDMM, Faculty of Health Sciences, University of Cape Town, South Africa
    Int J Cardiol 167:2204-9. 2013
  4. pmc Medication adherence, self-care behaviour and knowledge on heart failure in urban South Africa: the Heart of Soweto study
    V Ruf
    Soweto Cardiovascular Research Unit, Department of Cardiology, Chris Hani Baragwanath Hospital, Soweto, Johannesburg, South Africa
    Cardiovasc J Afr 21:86-92. 2010
  5. ncbi request reprint Predictors of outcome in 176 South African patients with peripartum cardiomyopathy
    Lori A Blauwet
    Department of Medicine, Division of CardiovascularDiseases, Mayo Clinic, Rochester, Minnesota, USA
    Heart 99:308-13. 2013
  6. pmc Bromocriptine treatment associated with recovery from peripartum cardiomyopathy in siblings: two case reports
    Gerd Peter Meyer
    Department of Cardiology and Angiology, MHH, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    J Med Case Reports 4:80. 2010
  7. ncbi request reprint Management of peripartum cardiomyopathy
    Karen Sliwa
    Soweto Cardiovascular Research Unit, Chris Hani Baragwanath Hospital, PO Bertsham 2013, Johannesburg, South Africa
    Curr Heart Fail Rep 5:238-44. 2008
  8. doi request reprint Incidence and characteristics of newly diagnosed rheumatic heart disease in urban African adults: insights from the heart of Soweto study
    Karen Sliwa
    Soweto Cardiovascular Research Unit, Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Bertsham, 2013 Johannesburg, Republic of South Africa
    Eur Heart J 31:719-27. 2010
  9. doi request reprint Forgotten cardiovascular diseases in Africa
    Karen Sliwa
    Hatter Cardiovascular Research Institute, Department of Medicine, Groote Schuur Hospital, University of Cape Town, Anzio Road, 7925 Cape Town, South Africa
    Clin Res Cardiol 99:65-74. 2010
  10. doi request reprint Immunosuppression as therapy for congestive heart failure
    Karen Sliwa
    Soweto Cardiovascular Research Unit, CH Baragwanath Hospital, University of the Witwatersrand, Johannesburg 2013, South Africa
    Lancet 371:184-6. 2008

Detail Information

Publications57

  1. ncbi request reprint Hypertension and hypertensive heart disease in African women
    Karen Sliwa
    Department of Medicine, Hatter Institute for Cardiovascular Research in Africa and IIDMM, Faculty of Health Sciences, Groote Schuur Hospital and University of Cape Town, Observatory, Cape Town, 7925, South Africa
    Clin Res Cardiol 103:515-23. 2014
    ....
  2. pmc The 12-lead ECG in peripartum cardiomyopathy
    Kemi Tibazarwa
    Hatter Institute for Cardiovascular Research in Africa, Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa
    Cardiovasc J Afr 23:322-9. 2012
    ..The value of the 12-lead electrocardiogram (ECG) to provide prognostic information in the deadly and disabling syndrome peripartum cardiomyopathy (PPCM) is unknown...
  3. doi request reprint Redefining the ECG in urban South Africans: electrocardiographic findings in heart disease-free Africans
    Karen Sliwa
    Hatter Institute for Cardiovascular Research in Africa and IIDMM, Faculty of Health Sciences, University of Cape Town, South Africa
    Int J Cardiol 167:2204-9. 2013
    ..The 12-lead electrocardiogram (ECG) represents an important diagnostic tool for detecting heart disease, but the "normal" ECG in those of African descent has yet to be definitively described...
  4. pmc Medication adherence, self-care behaviour and knowledge on heart failure in urban South Africa: the Heart of Soweto study
    V Ruf
    Soweto Cardiovascular Research Unit, Department of Cardiology, Chris Hani Baragwanath Hospital, Soweto, Johannesburg, South Africa
    Cardiovasc J Afr 21:86-92. 2010
    ..There is a paucity of data on treatment adherence in patients with chronic heart failure (CHF) in Africa...
  5. ncbi request reprint Predictors of outcome in 176 South African patients with peripartum cardiomyopathy
    Lori A Blauwet
    Department of Medicine, Division of CardiovascularDiseases, Mayo Clinic, Rochester, Minnesota, USA
    Heart 99:308-13. 2013
    ..Identify novel prognostic factors for patients with peripartum cardiomyopathy (PPCM)...
  6. pmc Bromocriptine treatment associated with recovery from peripartum cardiomyopathy in siblings: two case reports
    Gerd Peter Meyer
    Department of Cardiology and Angiology, MHH, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    J Med Case Reports 4:80. 2010
    ..Peripartum cardiomyopathy is a rare form of cardiomyopathy, with heterogeneous presentation occurring in women between one-month antepartum and six months postpartum. It carries a poor prognosis and a high risk of mortality...
  7. ncbi request reprint Management of peripartum cardiomyopathy
    Karen Sliwa
    Soweto Cardiovascular Research Unit, Chris Hani Baragwanath Hospital, PO Bertsham 2013, Johannesburg, South Africa
    Curr Heart Fail Rep 5:238-44. 2008
    ..This review summarizes recent data charting the incidence, recent advances in the understanding of the pathophysiology of PPCM, and outlines the current treatment options available...
  8. doi request reprint Incidence and characteristics of newly diagnosed rheumatic heart disease in urban African adults: insights from the heart of Soweto study
    Karen Sliwa
    Soweto Cardiovascular Research Unit, Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Bertsham, 2013 Johannesburg, Republic of South Africa
    Eur Heart J 31:719-27. 2010
    ..Little is known on the incidence and clinical characteristics of newly diagnosed rheumatic heart disease (RHD) in adulthood from urban African communities in epidemiologic transition...
  9. doi request reprint Forgotten cardiovascular diseases in Africa
    Karen Sliwa
    Hatter Cardiovascular Research Institute, Department of Medicine, Groote Schuur Hospital, University of Cape Town, Anzio Road, 7925 Cape Town, South Africa
    Clin Res Cardiol 99:65-74. 2010
    ..We present our perspective on forgotten cardiovascular disease in Africa in the context of the epidemic of cardiovascular disease due to global changes in life style...
  10. doi request reprint Immunosuppression as therapy for congestive heart failure
    Karen Sliwa
    Soweto Cardiovascular Research Unit, CH Baragwanath Hospital, University of the Witwatersrand, Johannesburg 2013, South Africa
    Lancet 371:184-6. 2008
  11. ncbi request reprint Evaluation of bromocriptine in the treatment of acute severe peripartum cardiomyopathy: a proof-of-concept pilot study
    Karen Sliwa
    Hatter Cardiovascular Research Institute, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Rd, Observatory, Cape Town 7925, South Africa
    Circulation 121:1465-73. 2010
    ..We identified prolactin, mainly its 16-kDa angiostatic and proapoptotic form, as a key factor in PPCM pathophysiology. Previous reports suggest that bromocriptine may have beneficial effects in women with acute onset of PPCM...
  12. doi request reprint Long-term outcome of peripartum cardiomyopathy in a population with high seropositivity for human immunodeficiency virus
    Karen Sliwa
    Soweto Cardiovascular Research Unit, Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg, South Africa
    Int J Cardiol 147:202-8. 2011
    ..Peripartum cardiomyopathy (PPCM) is a rare cardiomyopathy with a high risk of mortality. The present study assessed clinical outcome and mortality over a 2-year period in an African cohort of 80 PPCM patients...
  13. doi request reprint Current state of knowledge on aetiology, diagnosis, management, and therapy of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of Cardiology Working Group on peripartum cardiomyopathy
    Karen Sliwa
    Hatter Cardiovascular Research Institute, University of Cape Town, Cape Town, South Africa
    Eur J Heart Fail 12:767-78. 2010
    ..Oxidative stress and the generation of a cardiotoxic subfragment of prolactin may play key roles in the pathophysiology of PPCM. In this regard, pharmacological blockade of prolactin offers the possibility of a disease-specific therapy...
  14. doi request reprint Reversal of IFN-gamma, oxLDL and prolactin serum levels correlate with clinical improvement in patients with peripartum cardiomyopathy
    Olaf Forster
    Soweto Cardiovascular Research Unit, Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg, South Africa
    Eur J Heart Fail 10:861-8. 2008
    ..Peripartum cardiomyopathy (PPCM) is characterized by acute onset of heart failure of unknown aetiology. We aimed to identify mechanisms involved in initiation and progression of the disease...
  15. ncbi request reprint Impact of initiating carvedilol before angiotensin-converting enzyme inhibitor therapy on cardiac function in newly diagnosed heart failure
    Karen Sliwa
    Department of Cardiology, Chris Hani Baragwanath Hospital, Johannesburg, South Africa
    J Am Coll Cardiol 44:1825-30. 2004
    ..The purpose of this research was to evaluate the therapeutic value of initiating a beta-blocker before an angiotensin-converting enzyme inhibitor (ACEI) in the treatment of heart failure...
  16. ncbi request reprint Peripartum cardiomyopathy: inflammatory markers as predictors of outcome in 100 prospectively studied patients
    Karen Sliwa
    Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, PO Bertsham 2013, Johannesburg, South Africa
    Eur Heart J 27:441-6. 2006
    ..We evaluated the prognostic role of multiple inflammatory markers in the plasma of a large cohort of African patients with PPCM...
  17. ncbi request reprint C-reactive protein predicts response to pentoxifylline in patients with idiopathic dilated cardiomyopathy
    Karen Sliwa
    Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, P O Bertsham, 2013, Johannesburg, South Africa
    Eur J Heart Fail 6:731-4. 2004
  18. doi request reprint Spectrum of heart disease and risk factors in a black urban population in South Africa (the Heart of Soweto Study): a cohort study
    Karen Sliwa
    Soweto Cardiovascular Research Unit, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg, South Africa
    Lancet 371:915-22. 2008
    ..We aimed to investigate the clinical range of disorders related to cardiovascular disease in patients presenting for the first time to a tertiary-care centre...
  19. ncbi request reprint Mortality in patients treated for tuberculous pericarditis in sub-Saharan Africa
    Bongani M Mayosi
    Department of Medicine, University of Cape Town
    S Afr Med J 98:36-40. 2008
    ..To determine the mortality rate and its predictors in patients with a presumptive diagnosis of tuberculous pericarditis in sub-Saharan Africa...
  20. ncbi request reprint Therapy of ischemic cardiomyopathy with the immunomodulating agent pentoxifylline: results of a randomized study
    Karen Sliwa
    Department of Cardiology, Chris Hani Baragwanath Hospital, Johannesburg, South Africa
    Circulation 109:750-5. 2004
    ..We also investigated the effect of therapy on levels of brain natriuretic peptide (NT-pro BNP), C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-alpha), and the marker of apoptosis, Fas/Apo-1...
  21. doi request reprint The clinical consequences and challenges of hypertension in urban-dwelling black Africans: insights from the Heart of Soweto Study
    Simon Stewart
    Soweto Cardiovascular Research Unit, Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg, Republic of South Africa
    Int J Cardiol 146:22-7. 2011
    ..There is a paucity of data to describe advanced forms of cardiovascular disease (CVD) in urban black Africans with hypertension (HT)...
  22. ncbi request reprint Outcome of subsequent pregnancy in patients with documented peripartum cardiomyopathy
    Karen Sliwa
    Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Bertsham 2013, Johannesburg, South Africa
    Am J Cardiol 93:1441-3, A10. 2004
    ..4 +/- 1.1 pg/ml at onset of subsequent pregnancy to 6.2 +/- 2.4 pg/ml at 1 month postpartum...
  23. ncbi request reprint Mapping the emergence of heart disease in a black, urban population in Africa: the Heart of Soweto Study
    Simon Stewart
    Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, BERTSHAM 2013 Johannesburg, Republic of South Africa
    Int J Cardiol 108:101-8. 2006
    ..The "Heart of Soweto Study" will systematically investigate the emergence of heart disease (HD) in a large urban population in South Africa...
  24. ncbi request reprint Predominance of heart failure in the Heart of Soweto Study cohort: emerging challenges for urban African communities
    Simon Stewart
    Soweto Cardiovascular Research Unit, Department of Cardiology, Chris Hani Baragwanath Hospital, Bertsham 2013, Johannesburg, South Africa
    Circulation 118:2360-7. 2008
    ..There is a paucity of data to describe the clinical characteristics of heart failure (HF) in urban African communities in epidemiological transition...
  25. ncbi request reprint Endotoxin-independent white cell cytokine production in haemodynamically stable patients with idiopathic dilated cardiomyopathy
    Richard Brooksbank
    Cardiovascular Pathophysiology Laboratory, School of Physiology, University of the Witwatersrand, Chris Hani Baragwanath Hospital and the National Health Laboratory Service, Johannesburg, South Africa
    Cardiovasc J S Afr 16:260-5. 2005
    ..In heart failure, increased circulating white cell tumour necrosis factor-alpha production could be attributed to elevated plasma endotoxin concentrations or an increase in white cell sensitivity to endotoxin...
  26. ncbi request reprint Effects of pentoxifylline on cytokine profiles and left ventricular performance in patients with decompensated congestive heart failure secondary to idiopathic dilated cardiomyopathy
    Karen Sliwa
    Heart Failure Research Unit, Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, P O Bertsham, 2013 Johannesburg, South Africa
    Am J Cardiol 90:1118-22. 2002
    ..05 compared with baseline and with placebo), effects that were not observed in the placebo-treated group. These data suggest that pentoxifylline may be a useful adjunct to conventional therapy in patients with severe heart failure...
  27. ncbi request reprint Sustained white cell cytokine activation in idiopathic dilated cardiomyopathy despite haemodynamic improvement with medical therapy
    Richard Brooksbank
    Cardiovascular Pathophysiology Research Unit, School of Physiology, University of the Witwatersrand, Chris Hani Baragwanath Hospital, South Africa
    Cardiovasc J S Afr 16:200-4. 2005
    ..These data suggest that mechanisms other than haemodynamic impairment and neurohumoral activation contribute to excess white cell TNF-alpha production in IDC...
  28. pmc Contribution of the human immunodeficiency virus/acquired immunodeficiency syndrome epidemic to de novo presentations of heart disease in the Heart of Soweto Study cohort
    Karen Sliwa
    Faculty of Health Sciences, Hatter Institute for Cardiovascular Research in Africa and IIDMM, University of Cape Town, Cape Town, South Africa
    Eur Heart J 33:866-74. 2012
    ..The Heart of Soweto Study provides a unique opportunity to identify the contribution of cardiac manifestations of this epidemic to de novo presentations of heart disease in an urban African community in epidemiological transition...
  29. doi request reprint Peripartum cardiomyopathy in Africa: challenges in diagnosis, prognosis, and therapy
    Kemi Tibazarwa
    Soweto Cardiovascular Research Unit, Chris Hani Baragwannath Hospital, The University of the Witwatersrand, Johannesburg, South Africa
    Prog Cardiovasc Dis 52:317-25. 2010
    ..New insights into the role of inflammatory, apoptotic, and other genetic pathways may improve prognosis through the early detection and more targeted treatment of PPCM...
  30. ncbi request reprint Effect of slow-release indapamide and perindopril compared with amlodipine on 24-hour blood pressure and left ventricular mass in hypertensive patients of African ancestry
    Elena N Libhaber
    Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, PO Bertsham, Johannesburg 2013, South Africa
    Am J Hypertens 17:428-32. 2004
    ....
  31. ncbi request reprint Peripartum cardiomyopathy
    Karen Sliwa
    Soweto Cardiovascular Research Unit, Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, P O Bertsham 2013, Johannesburg, South Africa
    Lancet 368:687-93. 2006
    ....
  32. ncbi request reprint Anaemia and renal function in heart failure due to idiopathic dilated cardiomyopathy
    Sally C Inglis
    Faculty of Health Sciences, University of Queensland, Brisbane, Australia, and Soweto Cardiovascular Research Unit, Department of Cardiology, Chris Hani Baragwanath Hospital, Johannesburg, Republic of South Africa
    Eur J Heart Fail 9:384-90. 2007
    ..Anaemia and renal dysfunction are common in patients with heart failure (HF). Most studies involve western cohorts with ischaemic aetiology receiving treatment likely to impair renal function...
  33. ncbi request reprint Readmission and death after an acute heart failure event: predictors and outcomes in sub-Saharan Africa: results from the THESUS-HF registry
    Karen Sliwa
    Department of Medicine, Faculty of Health Sciences, Hatter Institute for Cardiovascular Research in Africa and the Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    Eur Heart J 34:3151-9. 2013
    ..We sought to describe factors prognostic of re-admission and death in this developing population...
  34. ncbi request reprint EURObservational Research Programme: a worldwide registry on peripartum cardiomyopathy (PPCM) in conjunction with the Heart Failure Association of the European Society of Cardiology Working Group on PPCM
    Karen Sliwa
    Hatter Institute for Cardiovascular Research in Africa, University of Cape Town, South Africa
    Eur J Heart Fail 16:583-91. 2014
    ....
  35. doi request reprint A time bomb of cardiovascular risk factors in South Africa: results from the Heart of Soweto Study "Heart Awareness Days"
    Kemi Tibazarwa
    Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg, South Africa
    Int J Cardiol 132:233-9. 2009
    ..However, data to describe the risk factor profile of affected communities is limited...
  36. ncbi request reprint HIV and the heart: the impact of antiretroviral therapy: a global perspective
    Friedrich Thienemann
    Clinical Infectious Diseases Research Initiative, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Wolfson Pavilion, Room S3 03 Level 3, Anzio Road, Observatory, Cape Town 7925, South Africa
    Eur Heart J 34:3538-46. 2013
    ....
  37. ncbi request reprint Epidemiology and etiology of cardiomyopathy in Africa
    Karen Sliwa
    Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg, South Africa
    Circulation 112:3577-83. 2005
    ..The primary objective of this review was to summarize the current state of knowledge on the epidemiology and etiology of cardiomyopathy in people living in Africa and to identify new avenues for research...
  38. ncbi request reprint The addition of pentoxifylline to conventional therapy improves outcome in patients with peripartum cardiomyopathy
    Karen Sliwa
    Department of Cardiology, Baragwanath Hospital, University of the Witwatersrand, PO Bertsham 2013, Johannesburg, South Africa
    Eur J Heart Fail 4:305-9. 2002
    ..04) was the only independent predictor of outcome. In conclusion, the results of this study suggest that the addition of pentoxifylline to conventional treatment, improves outcome in patients with peripartum cardiomyopathy...
  39. doi request reprint Prognostic significance of ECG abnormalities for mortality risk in acute heart failure: insight from the Sub-Saharan Africa Survey of Heart Failure (THESUS-HF)
    Anastase Dzudie
    DOUALA General Hospital, Douala, and Buea Faculty of Health Sciences, Buea, Cameroon Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    J Card Fail 20:45-52. 2014
    ..The aim of this study was to assess the predictive utility of 12-lead electrocardiogram (ECG) abnormalities among Africans with acute heart failure (HF)...
  40. pmc Different lipid profiles according to ethnicity in the Heart of Soweto study cohort of de novo presentations of heart disease
    Karen Sliwa
    Hatter Institute for Cardiovascular Research in Africa and IIDMM, Faculty of Health Sciences, University of Cape Town, South Africa
    Cardiovasc J Afr 23:389-95. 2012
    ..Historically, sub-Saharan Africa has reported low levels of atherosclerotic cardiovascular disease (CVD). However as these populations undergo epidemiological transition, this may change...
  41. doi request reprint Recent advances in the epidemiology, pathogenesis and prognosis of acute heart failure and cardiomyopathy in Africa
    Karen Sliwa
    Hatter Institute for Cardiovascular Research in Africa, Department of Medicine, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa
    Heart 99:1317-22. 2013
    ..The key challenges of management of heart failure are the urgent need to increase the use of proven treatments by physicians, and the control of hypertension in primary care and at the population level...
  42. ncbi request reprint Cardiac amyloidosis presenting as pseudo-hypertrophic cardiomyopathy
    Alexander Papachan
    Department of Cardiology, Chris Hani Baragwanath Hospital, Johannesburg, South Africa
    Cardiovasc J S Afr 15:136-8. 2004
    ..While in most patients the two conditions are easily differentiated, we present in this report a case of amyloidosis that mimicked hypertrophic cardiomyopathy so closely that it required endomyocardial biopsy to establish the diagnosis...
  43. doi request reprint Peripartum cardiomyopathy: update 2012
    Katrin Bachelier-Walenta
    aKlinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar bDepartment of Cardiology und Angiology, Medizinische Hochschule Hannover, Hannover, Germany cFaculty of Health Sciences, Hatter Institute for Cardiovascular Research in Africa and IIDMM, University of Cape Town, Cape Town, South Africa
    Curr Opin Crit Care 19:397-403. 2013
    ..This review focuses on new data and aspects in terms of diagnosis, causes of disease, pharmacological therapy, and management of delivery in patients with PPCM...
  44. ncbi request reprint Elevated risk factors but low burden of heart disease in urban African primary care patients: a fundamental role for primary prevention
    Simon Stewart
    Preventative Health, Baker IDI Heart and Diabetes Institute, Melbourne, Australia
    Int J Cardiol 158:205-10. 2012
    ..Few data describe the case burden of heart disease and cardiovascular risk factors relative to other conditions in urban Africans seeking primary health care...
  45. pmc Antiphospholipid antibodies in black south africans with hiv and acute coronary syndromes: prevalence and clinical correlates
    Anthony C Becker
    Division of Cardiology, Chris Hani Baragwanath Hospital and University of the Witwatersrand, Johannesburg, South Africa
    BMC Res Notes 4:379. 2011
    ..abstract:..
  46. ncbi request reprint Predictors of hospitalisations for heart failure and mortality in patients with pulmonary hypertension associated with left heart disease: a systematic review
    Anastase Dzudie
    Douala General Hospital and Buea Faculty of Health Sciences, Douala, Cameroon Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    BMJ Open 4:e004843. 2014
    ..We conducted a systematic review to investigate the predictors of hospitalisations for heart failure and mortality in patients with PH-LHD...
  47. ncbi request reprint Current issues in the diagnosis and management of peripartum cardiomyopathy
    Olaf Forster
    University of the Witwatersrand, Johannesburg Division of Cardiology, Chris Hani Baragwanath Hospital Soweto Cardiovascular Research Unit, 2013 Soweto, South Africa
    Womens Health (Lond Engl) 2:587-96. 2006
    ....
  48. ncbi request reprint An aldosterone synthase gene variant is associated with improvement in left ventricular ejection fraction in dilated cardiomyopathy
    Armindo D Tiago
    Cardiovascular Genomics and Heart Failure Research Units, Department of Physiology, Chris Hani Baragwanath Hospital and the University of the Witwatersrand, Johannesburg, South Africa
    Cardiovasc Res 54:584-9. 2002
    ....
  49. ncbi request reprint Contemporary profile of acute heart failure in Southern Nigeria: data from the Abeokuta Heart Failure Clinical Registry
    Okechukwu S Ogah
    Division of Cardiology, Department of Medicine, University College Hospital, Ibadan, Nigeria Soweto Cardiovascular Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa Electronic address
    JACC Heart Fail 2:250-9. 2014
    ..The aim of this study was to determine the contemporary profile, clinical characteristics, and intrahospital outcomes of acute heart failure (AHF) in an African urban community...
  50. doi request reprint Incidence and prevalence of pregnancy-related heart disease
    Karen Sliwa
    Department of Medicine, Faculty of Health Sciences, Hatter Institute for Cardiovascular Research in Africa and IIDMM, University of Cape Town, Cape Town, South Africa
    Cardiovasc Res 101:554-60. 2014
    ..This review summarizes the current knowledge of the incidence and prevalence of pregnancy-related cardiovascular disease in women presenting pre- or post-partum. ..
  51. doi request reprint Relationship between left ventricular geometry and soluble ST2 in a cohort of hypertensive patients
    Dike B Ojji
    Cardiology Unit, Department of Medicine, University of Abuja Teaching Hospital, Gwagwalada, Abuja, Nigeria Department of Medicine, Faculty of Health Sciences, Hatter Institute for Cardiovascular Research in Africa, University of Cape Town, Cape Town, South Africa
    J Clin Hypertens (Greenwich) 15:899-904. 2013
    ..4±8.4 ng/mL vs 14.3±5.4 ng/mL, P<.002). Therefore, soluble ST2 level is not only affected by hypertensive LV, but may be a future biomarker in differentiating concentric hypertrophy from normal geometry in hypertension. ..
  52. pmc Feeding the emergence of advanced heart disease in Soweto: a nutritional survey of black African patients with heart failure
    Sandra Pretorius
    Soweto Cardiovascular Research Unit, Department of Cardiology, Chris Hani Baragwanath Hospital, University of Witwatersrand, Johannesburg, South Africa
    Cardiovasc J Afr 23:245-51. 2012
    ..To describe dietary habits and potential nutritional deficiencies in black African patients diagnosed with heart failure (HF)...
  53. doi request reprint Women's cardiovascular health in Africa
    Ana Olga Mocumbi
    Instituto Nacional de Saude, Maputo, Mozambique
    Heart 98:450-5. 2012
    ..It highlights the gaps in knowledge and the paucity of data in most of these aspects...
  54. pmc Clinical characteristics and initial management of patients with tuberculous pericarditis in the HIV era: the Investigation of the Management of Pericarditis in Africa (IMPI Africa) registry
    Bongani M Mayosi
    The Cardiac Clinic, Department of Medicine, University of Cape Town, E25 Groote Schuur Hospital, Observatory 7925, South Africa
    BMC Infect Dis 6:2. 2006
    ....
  55. ncbi request reprint Impact of pregnancy-related heart failure on humoral immunity: clinical relevance of G3-subclass immunoglobulins in peripartum cardiomyopathy
    Rahat S Warraich
    Department of Cardiothoracic Surgery, National Heart and Lung Institute, Imperial College School of Medicine, Royal Brompton and Harefield Trust, Harefield Hospital, Middlesex, England, UK
    Am Heart J 150:263-9. 2005
    ..Therefore, given that progressive gestation is associated with immunologic incompetence, we sought to study the relative impact of pregnancy-related onset of HF on humoral immunity...
  56. ncbi request reprint Contemporary use of adjunctive corticosteroids in tuberculous pericarditis
    Charles S Wiysonge
    Int J Cardiol 124:388-90. 2008
    ..These data provide a justification for the establishment of adequately powered randomised clinical trials to assess the effectiveness of adjunctive corticosteroids in patients with tuberculous pericarditis...
  57. ncbi request reprint A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy
    Denise Hilfiker-Kleiner
    Department of Cardiology and Angiology, MHH, 30625 Hannover, Germany
    Cell 128:589-600. 2007
    ..Thus, a biologically active derivative of the pregnancy hormone prolactin mediates PPCM, implying that inhibition of prolactin release may represent a novel therapeutic strategy for PPCM...