Afef Slimani

Summary

Publications

  1. doi request reprint Effect of mutations in LDLR and PCSK9 genes on phenotypic variability in Tunisian familial hypercholesterolemia patients
    Afef Slimani
    Research Unit of Genetic and Biological Factors of Atherosclerosis, Faculty of Medicine, Monastir 5000, Tunisia
    Atherosclerosis 222:158-66. 2012
  2. pmc Hsp70-2 gene polymorphism: susceptibility implication in Tunisian patients with coronary artery disease
    Mohamed Yahia Hrira
    Laboratory of Biochemistry CHU Hached, Sousse, Tunisia
    Diagn Pathol 7:88. 2012
  3. doi request reprint Genomic characterization of two deletions in the LDLR gene in Tunisian patients with familial hypercholesterolemia
    Awatef Jelassi
    Research Unit of Genetic and Biologic Factors of Atherosclerosis, Faculty of Medicine, Monastir, University of Monastir, Tunisia
    Clin Chim Acta 414:146-51. 2012
  4. doi request reprint Matrix metalloproteinase-1 and matrix metalloproteinase-12 gene polymorphisms and the outcome of coronary artery disease
    Imen Jguirim-Souissi
    Unit of Research, Genetic and Biologic Factors of Atherosclerosis, Faculty of Medicine, Monastir, Tunisia
    Coron Artery Dis 22:388-93. 2011
  5. doi request reprint Moderate phenotypic expression of familial hypercholesterolemia in Tunisia
    Awatef Jelassi
    Research Unit of Genetic and Biological Factors of Atherosclerosis, Faculty of Medicine, Monastir, Tunisia
    Clin Chim Acta 411:735-8. 2010

Collaborators

  • Catherine Boileau
  • Marianne Abifadel
  • Imen Jguirim-Souissi
  • Awatef Jelassi
  • Mohamed Yahia Hrira
  • Mohamed Najah
  • Mathilde Varret
  • Mohamed Naceur Slimane
  • Imen Jguirim
  • Faouzi Addad
  • Habib Mosbah
  • Henda Chahed
  • Jawher Mzid
  • Latifa Chkioua
  • Hamda Ben Khaldoun
  • Jean Pierre Rabes
  • Salima Ferchichi
  • Abdelhedi Miled
  • Samir M'rabet
  • Mustapha Rouis
  • Lamia Boughamoura
  • Jawhar Mzid
  • Abdelmajid Abid
  • Fawzi Maatouk
  • Moncef Fkih

Detail Information

Publications5

  1. doi request reprint Effect of mutations in LDLR and PCSK9 genes on phenotypic variability in Tunisian familial hypercholesterolemia patients
    Afef Slimani
    Research Unit of Genetic and Biological Factors of Atherosclerosis, Faculty of Medicine, Monastir 5000, Tunisia
    Atherosclerosis 222:158-66. 2012
    ..ADH subjects carrying a mutation in LDLR present highly variable plasma LDL-cholesterol (LDL-C). This variability might be due to environmental factors or the effect of some modifying genes such as PCSK9 and APOE...
  2. pmc Hsp70-2 gene polymorphism: susceptibility implication in Tunisian patients with coronary artery disease
    Mohamed Yahia Hrira
    Laboratory of Biochemistry CHU Hached, Sousse, Tunisia
    Diagn Pathol 7:88. 2012
    ..Heat shock protein genes are involved in the progress of CAD. This implies that genetic variants of Hsp70-2 genes might contribute to the development of the CAD...
  3. doi request reprint Genomic characterization of two deletions in the LDLR gene in Tunisian patients with familial hypercholesterolemia
    Awatef Jelassi
    Research Unit of Genetic and Biologic Factors of Atherosclerosis, Faculty of Medicine, Monastir, University of Monastir, Tunisia
    Clin Chim Acta 414:146-51. 2012
    ..These two large rearrangements in the LDLR gene are the first to be described in the Tunisian population, increasing the spectrum of ADH-causative mutations...
  4. doi request reprint Matrix metalloproteinase-1 and matrix metalloproteinase-12 gene polymorphisms and the outcome of coronary artery disease
    Imen Jguirim-Souissi
    Unit of Research, Genetic and Biologic Factors of Atherosclerosis, Faculty of Medicine, Monastir, Tunisia
    Coron Artery Dis 22:388-93. 2011
    ..In this study, we investigated the association between matrix metalloproteinase-1 (MMP-1) G-1607GG, MMP-12 A-82G and MMP-12 A1082G genotypes and haplotypes and the prognosis of coronary artery disease (CAD)...
  5. doi request reprint Moderate phenotypic expression of familial hypercholesterolemia in Tunisia
    Awatef Jelassi
    Research Unit of Genetic and Biological Factors of Atherosclerosis, Faculty of Medicine, Monastir, Tunisia
    Clin Chim Acta 411:735-8. 2010
    ..Xanthomas and coronary heart diseases (CHD) at an early age are the major clinical manifestations of the disease...