Rajeev K Singla
Igoli J, Gray A, Clements C, Kantheti P, Singla R. Antitrypanosomal activity & docking studies of isolated constituents from the lichen Cetraria islandica: possibly multifunctional scaffolds. Curr Top Med Chem. 2014;14:1014-21 pubmed
..Hydrophobicity played a significant role in their antitrypanosomal activity. ..
Igoli N, Clements C, Singla R, Igoli J, Uche N, Gray A. Antitrypanosomal activity & docking studies of components of Crateva adansonii DC leaves: novel multifunctional scaffolds. Curr Top Med Chem. 2014;14:981-90 pubmed
Pokuri S, Singla R, Bhat V, Shenoy G. Insights on the antioxidant potential of 1, 2, 4-triazoles: synthesis, screening & QSAR studies. Curr Drug Metab. 2014;15:389-97 pubmed
..The 2D-QSAR models correlate with the in vitro results and explain the salient structural features predominant in the molecules responsible for antioxidant activity. ..
Gundamaraju R, Singla R, Vemuri R, Sekaran S. Functional correlation of medicinal chemistry and Entamoeba histolytica treatment: an emphasis on the past, present and future chemotherapy. Mini Rev Med Chem. 2015;15:211-9 pubmed
Singla R. Homology modeling of MDR1 gene MDR1_ENTHI of E. histolytica & its molecular docking with anti-entamoeba histolytica agents. Curr Top Med Chem. 2015;15:980-9 pubmed
..Henceforth, none of the molecules will probably be effective for the multidrug resistant strains of E. histolytica. ..
Singla R. Editorial: in silico drug design and medicinal chemistry). Curr Top Med Chem. 2015;15:971-2 pubmed
..Articles will be a treasure box consisting of employment of computational methods for unprecedented molecules. The issue will be sure an endorsement for international readership and researchers. ..
Singla R, Bhat G V. QSAR model for predicting the fungicidal action of 1,2,4-triazole derivatives against Candida albicans. J Enzyme Inhib Med Chem. 2010;25:696-701 pubmed publisher
..The model is not only able to predict the activity of new compounds but also explains the important region in the molecules in a quantitative manner. ..