Pratibha Singhi

..Prevention of CNS infections is the only definitive way forward to reduce the burden of epilepsy in developing countries...

..We report a rare nonepileptic manifestation of neurocysticercosis: midbrain neurocysticercosis presenting as sudden-onset ptosis in 2 children. To our knowledge, this has not been reported previously in children...

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..Extraparenchymal NCC has a guarded prognosis but it is rare in children. In endemic areas NCC must be considered in the differential diagnosis of seizures and various other neurological disorders...

..When pharmacological coma is initiated, the child needs to be shifted to pediatric intensive care unit for proper monitoring and titration of medications...

..A combination of albendazole and praziquantel was more effective than albendazole alone in destroying Taenia cysts in an animal model. There are no such studies in humans...

..Children in the corticosteroid group had significantly more seizure recurrences while on antiepilepsy drugs...

..Weight loss, decreased concentration in school, sedation, and parasthesias were important side effects with topiramate. Most of these side effects were mild to moderate and were not significant enough to cause dropout from the study...

..Neurocysticercosis must be considered in the differential diagnosis of seizures and a wide variety of neurologic disorders, particularly in endemic areas...

..Short-term hyperventilation (to achieve PCO(2) ≈ 30 mm Hg) using bag ventilation can be resorted to if signs of impending herniation are present...

..To study the long-term neurological and developmental outcome and the clinical and laboratory predictors of sequelae in children with acute bacterial meningitis (ABM)...

..In India WS is often diagnosed late because of lack of awareness. Adverse perinatal events are important etiological factors. Non-affordability of ACTH and Vigabatrin prompts the use of prednisolone in most cases...

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..To determine the extent to which the developmental profile of children less than 4 years can help in distinguishing children with autism from children with developmental delay...

..Risperidone improved global functioning and social responsiveness while reducing hyperactivity and aggression in children with autism and was well tolerated...

..It assesses whether the extent of agreement between informants improves by making the ADHD criteria more flexible...

..6%) and diplegia (15.8%). Epilepsy in cerebral palsy is seen in about one third of cases; it is often severe and difficult to control particularly in children with mental retardation...

..Observations in small, uncontrolled clinical trials that short course therapy is as effective as longer regimens must be tested by proper trials...

..However, stroke following intraoral trauma is rare. A high index of suspicion of neurological complications following apparently asymptomatic oral trauma helps to identify this peculiar form of childhood stroke...

..It is concluded that intravenous sodium valproate is an effective alternative to diazepam infusion in controlling refractory status epilepticus in children and is free of respiratory depression and hypotension...

..To examine the quality of life of children with epilepsy and to identify the demographic, disease related, and behavioral and emotional functioning variables in the prediction of quality of life of children with epilepsy...

..Whereas Botulinum toxin can be a valuable adjunct in select cases, it should not be projected as a panacea for children with spastic cerebral palsy...

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..Irrespective of the cause, generalized weakness frequently affects respiratory and bulbar function. Such children need careful monitoring and respiratory support...

..To assess diagnostic stability of initial autism spectrum disorder (ASD) diagnosed in children three years or less...

..The low-positive predictive value would lead to over referrals but a large number of these children would benefit from medical attention...

..A simple practical approach to diagnosing and treating children with Bell's palsy is suggested...

..Concerns both about over-diagnosis and under-diagnosis have been expressed in the literature. Management emphasizing parental counseling, behavior management strategies, and appropriate pharmacotherapy is recommended...

..The outcome depends on the underlying etiology, age, rapidity of SE and adequacy of care. Adherence to a time-framed protocol in the emergency department helps in improving the final outcome...