Kuleesha Y, Puah W, Lin F, Wasser M. FMAj: a tool for high content analysis of muscle dynamics in Drosophila metamorphosis. BMC Bioinformatics. 2014;15 Suppl 16:S6 pubmed publisher
..Extending our approach to a genome-wide scale has the potential to identify new genes involved in muscle size regulation. ..
Kriston Vizi J, Thong N, Poh C, Yee K, Ling J, Kraut R, et al
. Gebiss: an ImageJ plugin for the specification of ground truth and the performance evaluation of 3D segmentation algorithms. BMC Bioinformatics. 2011;12:232 pubmed publisher
..Gebiss was developed as a cross-platform ImageJ plugin and is freely available on the web at http://imaging.bii.a-star.edu.sg/projects/gebiss/. ..
Du T, Puah W, Wasser M. Cell cycle phase classification in 3D in vivo microscopy of Drosophila embryogenesis. BMC Bioinformatics. 2011;12 Suppl 13:S18 pubmed publisher
..Cell cycle classification in live animals can be used for automated phenotyping and to improve the performance of automated cell tracking. ..
Chinta R, Tan J, Wasser M. The study of muscle remodeling in Drosophila metamorphosis using in vivo microscopy and bioimage informatics. BMC Bioinformatics. 2012;13 Suppl 17:S14 pubmed publisher
..Our methodology can easily be scaled up for genome-wide genetic screens using readily available resources for RNAi based gene silencing in Drosophila and other animal models. ..
Wasser M, Chia W. The extrachromosomal East protein of Drosophila can associate with polytene chromosomes and regulate gene expression. PLoS ONE. 2007;2:e412 pubmed
..We propose that EAST acts as an ion sensor that modulates gene expression in response to changing intracellular ion concentrations. ..
Wasser M, Bte Osman Z, Chia W. EAST and Chromator control the destruction and remodeling of muscles during Drosophila metamorphosis. Dev Biol. 2007;307:380-93 pubmed
..Overexpression of EAST-GFP can prevent the disintegration of polytene chromosomes during programmed cell death. We propose that Chro activates and east inhibits processes and genes involved in tissue destruction and remodeling. ..