Gen Hua Yue

Summary

Affiliation: Temasek Life Sciences Laboratory
Country: Singapore

Publications

  1. ncbi request reprint The complete nucleotide sequence of the mitochondrial genome of Tetraodon nigroviridis
    Gen Hua Yue
    Molecular Population Genetics Group, Temasek Life Sciences Lab, 1 Research Link, National University of Singapore, Singapore
    DNA Seq 17:115-21. 2006
  2. doi request reprint The intestinal microbiome of fish under starvation
    Jun Hong Xia
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore 117604, Republic of Singapore
    BMC Genomics 15:266. 2014
  3. pmc Tracing Asian seabass individuals to single fish farms using microsatellites
    Gen Hua Yue
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore
    PLoS ONE 7:e52721. 2012
  4. pmc An approach for jatropha improvement using pleiotropic QTLs regulating plant growth and seed yield
    Fei Sun
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, 117604, Singapore, Singapore
    Biotechnol Biofuels 5:42. 2012
  5. pmc Evidence for female-biased dispersal in the protandrous hermaphroditic Asian Seabass, Lates calcarifer
    Gen Hua Yue
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Republic of Singapore
    PLoS ONE 7:e37976. 2012
  6. ncbi request reprint Mutation rate and pattern of microsatellites in common carp (Cyprinus carpio L.)
    G H Yue
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, Singapore, Singapore
    Genetica 129:329-31. 2007
  7. pmc Discovery of four natural clones in a crayfish species Procambarus clarkii
    G H Yue
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, 117604 Singapore
    Int J Biol Sci 4:279-82. 2008
  8. pmc Molecular evidence for high frequency of multiple paternity in a freshwater shrimp species Caridina ensifera
    Gen Hua Yue
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore
    PLoS ONE 5:e12721. 2010
  9. doi request reprint A new problem with cross-species amplification of microsatellites: generation of non-homologous products
    Gen Hua Yue
    Reproductive Genomics, Strategic Research Program, Temasek Life Sciences Laboratory, Singapore
    Dongwuxue Yanjiu 31:131-40. 2010
  10. pmc A simple and efficient method for isolating polymorphic microsatellites from cDNA
    Gen Hua Yue
    Molecular Population Genetics Group, Temasek Life Sciences Lab, 1 Research Link, National University of Singapore, 117604 Singapore
    BMC Genomics 10:125. 2009

Collaborators

Detail Information

Publications35

  1. ncbi request reprint The complete nucleotide sequence of the mitochondrial genome of Tetraodon nigroviridis
    Gen Hua Yue
    Molecular Population Genetics Group, Temasek Life Sciences Lab, 1 Research Link, National University of Singapore, Singapore
    DNA Seq 17:115-21. 2006
    ..The complete mtDNA sequence and SNPs in its control region will be useful in studying fish evolution, in differentiating different Tetraodon species and in analyzing genetic diversity within T. nigroviridis...
  2. doi request reprint The intestinal microbiome of fish under starvation
    Jun Hong Xia
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore 117604, Republic of Singapore
    BMC Genomics 15:266. 2014
    ..To address this shortcoming, we determined the microbial gene catalogue, and investigated changes in the microbial composition and host-microbe interactions in the intestine of Asian seabass in response to starvation...
  3. pmc Tracing Asian seabass individuals to single fish farms using microsatellites
    Gen Hua Yue
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore
    PLoS ONE 7:e52721. 2012
    ..By combining rapid DNA extraction, and high-throughput genotyping of selected microsatellites, it is possible to conduct routine genetic traceability with high accuracy in Asian seabass...
  4. pmc An approach for jatropha improvement using pleiotropic QTLs regulating plant growth and seed yield
    Fei Sun
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, 117604, Singapore, Singapore
    Biotechnol Biofuels 5:42. 2012
    ..abstract:..
  5. pmc Evidence for female-biased dispersal in the protandrous hermaphroditic Asian Seabass, Lates calcarifer
    Gen Hua Yue
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Republic of Singapore
    PLoS ONE 7:e37976. 2012
    ..Studies of dispersal using data from DNA markers and tagging-recapture in hermaphroditic fish species could enhance our understanding of patterns of dispersal in fish...
  6. ncbi request reprint Mutation rate and pattern of microsatellites in common carp (Cyprinus carpio L.)
    G H Yue
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, Singapore, Singapore
    Genetica 129:329-31. 2007
    ..52 x 10(-4) and 1.63 x 10(-3)). The change of allele size was between +2 to -5 repeat units, assuming that the mutation allele arose from the parental allele most similar in size to the mutant...
  7. pmc Discovery of four natural clones in a crayfish species Procambarus clarkii
    G H Yue
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, 117604 Singapore
    Int J Biol Sci 4:279-82. 2008
    ..Phylogenetic analysis using microsatellite genotypes suggests recent origin of the four clones. Sequencing a part of the mitochondrial gene Cox I confirmed that the four clones were from the species Procambarus clarkii...
  8. pmc Molecular evidence for high frequency of multiple paternity in a freshwater shrimp species Caridina ensifera
    Gen Hua Yue
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore
    PLoS ONE 5:e12721. 2010
    ..Due to its small body size and low fecundity, this species is an ideal species to study the occurrence and frequency of multiple paternity and to understand of how the low fecundity species persist and evolve...
  9. doi request reprint A new problem with cross-species amplification of microsatellites: generation of non-homologous products
    Gen Hua Yue
    Reproductive Genomics, Strategic Research Program, Temasek Life Sciences Laboratory, Singapore
    Dongwuxue Yanjiu 31:131-40. 2010
    ..Therefore, we propose that sequence analysis of cross-amplification products should be conducted prior to application of cross-species amplification of microsatellites...
  10. pmc A simple and efficient method for isolating polymorphic microsatellites from cDNA
    Gen Hua Yue
    Molecular Population Genetics Group, Temasek Life Sciences Lab, 1 Research Link, National University of Singapore, 117604 Singapore
    BMC Genomics 10:125. 2009
    ..We developed a simple and efficient method for isolation of microsatellites from cDNA in fish...
  11. pmc The complete mitochondrial genome of a basal teleost, the Asian arowana (Scleropages formosus, Osteoglossidae)
    Gen Hua Yue
    Reproductive Genomics Group, Temasek Life Sciences Laboratory, Singapore
    BMC Genomics 7:242. 2006
    ..In this paper, we report the complete mitochondrial genome sequence of Asian arowana, a basal bonytongue fish species, which belongs to the order of Osteoglossiformes...
  12. pmc A high-resolution linkage map for comparative genome analysis and QTL fine mapping in Asian seabass, Lates calcarifer
    Chun Ming Wang
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, National University of Singapore, Singapore
    BMC Genomics 12:174. 2011
    ..Here, we report a high-resolution linkage map with 790 microsatellites and SNPs, comparative analysis of synteny, fine-mapping of QTL and the identification of potential candidate genes for growth traits...
  13. pmc A consensus linkage map of the grass carp (Ctenopharyngodon idella) based on microsatellites and SNPs
    Jun Hong Xia
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, National University of Singapore, 117604 Republic of Singapore
    BMC Genomics 11:135. 2010
    ....
  14. pmc Construction of a BAC library and mapping BAC clones to the linkage map of Barramundi, Lates calcarifer
    Chun Ming Wang
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, 117604, Singapore
    BMC Genomics 9:139. 2008
    ..We reported herein a bacterial artificial chromosome (BAC) library and the mapping of BAC clones to the linkage map...
  15. pmc A microsatellite linkage map of Barramundi, Lates calcarifer
    Chun Ming Wang
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, National University of Singapore, 117604 Singapore, Republic of Singapore
    Genetics 175:907-15. 2007
    ..nigrovidiris. The map will not only enable the mapping of quantitative trait loci, but also provide new resources for understanding the evolution of fish genomes...
  16. pmc A microsatellite-based linkage map of salt tolerant tilapia (Oreochromis mossambicus x Oreochromis spp.) and mapping of sex-determining loci
    Feng Liu
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore
    BMC Genomics 14:58. 2013
    ..A linkage map is an essential framework for mapping QTL for important traits, positional cloning of genes and understanding of genome evolution...
  17. pmc A first generation microsatellite- and SNP-based linkage map of Jatropha
    Chun Ming Wang
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore
    PLoS ONE 6:e23632. 2011
    ..The first generation linkage map and the data of comparative mapping could lay a solid foundation for QTL mapping of agronomic traits, marker-assisted breeding and cloning genes responsible for phenotypic variation...
  18. pmc Whole genome scanning and association mapping identified a significant association between growth and a SNP in the IFABP-a gene of the Asian seabass
    Jun Hong Xia
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, 117604 Singapore, Singapore
    BMC Genomics 14:295. 2013
    ..We conducted QTL mapping for growth traits in an Asian seabass F(2) family with 359 individuals using 123 microsatellites and 22 SNPs, and performed association mapping in four populations with 881 individuals...
  19. pmc Isolation and identification of miRNAs in Jatropha curcas
    Chun Ming Wang
    Temasek Life Sciences Laboratory, National University of Singapore, Singapore
    Int J Biol Sci 8:418-29. 2012
    ..Four targets were identified for JcumiR004. By silencing JcumiR004 primary miRNA, expressions of the four target genes were up-regulated and oil composition were modulated significantly, indicating diverse functions of JcumiR004...
  20. pmc A genome scan for quantitative trait loci affecting growth-related traits in an F1 family of Asian seabass (Lates calcarifer)
    Chun Ming Wang
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, 117604, Singapore
    BMC Genomics 7:274. 2006
    ..The recent construction of a first generation linkage map of Asian seabass with 240 microsatellites provides a good opportunity to determine the number and position of QTL, and the magnitude of QTL effects with a genome scan...
  21. pmc Molecular parentage analysis is essential in breeding Asian seabass
    Peng Liu
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, National University of Singapore, Singapore
    PLoS ONE 7:e51142. 2012
    ..8-97.0%) and gene diversities (94.8-97.1%) were maintained. These observations suggest that a routine molecular parentage analysis is required to maintain both allelic and gene diversity in breeding Asian seabass...
  22. pmc Analysis of the Asian seabass transcriptome based on expressed sequence tags
    Jun Hong Xia
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, National University of Singapore
    DNA Res 18:513-22. 2011
    ..The unique EST sequences are being used in developing a cDNA microarray to examine global gene expression and will also facilitate future whole-genome sequence assembly and annotation of Asian seabass and comparative genomics...
  23. doi request reprint Mapping quantitative trait loci for omega-3 fatty acids in Asian seabass
    Jun Hong Xia
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Singapore
    Mar Biotechnol (NY) 16:1-9. 2014
    ....
  24. pmc Mapping QTLs for oil traits and eQTLs for oleosin genes in jatropha
    Peng Liu
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, National University of Singapore, Singapore
    BMC Plant Biol 11:132. 2011
    ..In this study, quantitative trait locus (QTL) and expression QTL analyses were applied to identify genetic factors that are relevant to seed oil traits in jatropha...
  25. pmc High prevalence of multiple paternity in the invasive crayfish species, Procambarus clarkii
    Gen Hua Yue
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, 117604 Republic of Singapore
    Int J Biol Sci 6:107-15. 2010
    ....
  26. doi request reprint Characterization of the LECT2 gene and its associations with resistance to the big belly disease in Asian seabass
    Gui Hong Fu
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, 117604 Singapore, Singapore
    Fish Shellfish Immunol 37:131-8. 2014
    ..The SNP markers in the gene associated with the resistance to bacterial pathogens may facilitate selecting Asian seabass resistant to bacterial diseases. ..
  27. pmc Analysis of stress-responsive transcriptome in the intestine of Asian seabass (Lates calcarifer) using RNA-seq
    Jun Hong Xia
    1Molecular Population Genetics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore117604, Singapore
    DNA Res 20:449-60. 2013
    ..This study is the first step towards the comprehensive understanding of the mechanisms underlying stress responses and supplies significant transcriptome resources for studying biological questions in non-model fish species. ..
  28. pmc Identification and analysis of immune-related transcriptome in Asian seabass Lates calcarifer
    Jun Hong Xia
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, National University of Singapore, 117604 Republic of Singapore
    BMC Genomics 11:356. 2010
    ....
  29. pmc Analysis of two lysozyme genes and antimicrobial functions of their recombinant proteins in Asian seabass
    Gui Hong Fu
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore
    PLoS ONE 8:e79743. 2013
    ..The SNP markers in the two genes associated with the resistance to bacterial pathogens may facilitate the selection of Asian seabass resistant to bacterial diseases. ..
  30. doi request reprint Molecular characterization and mapping of Fgf21 gene in a foodfish species asian seabass
    Le Wang
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore
    PLoS ONE 9:e90172. 2014
    ..These results not only provide important information of the functions of Fgf21, but also suggest that the SNP in this gene can be used as a marker in selecting fast-growing individuals of Asian seabass. ..
  31. pmc Identification and characterization of 63 MicroRNAs in the Asian seabass Lates calcarifer
    Jun Hong Xia
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Republic of Singapore
    PLoS ONE 6:e17537. 2011
    ..Here, we described an approach to identify conserved miRNAs and characterized their expression patterns in different tissues for the first time in a food fish species Asian seabass (Lates calcarifer)...
  32. pmc Identification of triploid individuals and clonal lines in Carassius auratus complex using microsatellites
    Zhiyi Bai
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, 117604 Singapore
    Int J Biol Sci 7:279-85. 2011
    ..A phylogenetic analysis of 94 individuals from China and Japan showed that triploid individuals and clonal lines have originated recurrently...
  33. pmc A first generation BAC-based physical map of the Asian seabass (Lates calcarifer)
    Jun Hong Xia
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore
    PLoS ONE 5:e11974. 2010
    ..A physical map is still lacking, although it is essential for positional cloning of genes located in quantitative trait loci (QTL) and assembly of whole genome sequences...
  34. ncbi request reprint A simple and affordable method for high-throughput DNA extraction from animal tissues for polymerase chain reaction
    Gen Hua Yue
    Reproductive Genomics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore 117604
    Electrophoresis 26:3081-3. 2005
    ....
  35. doi request reprint Eleven polymorphic microsatellites isolated from red swamp crayfish, Procambarus clarkii
    Ze Yuan Zhu
    Molecular Population Genetics Group, Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, 117604 Singapore
    Mol Ecol Resour 8:796-8. 2008
    ..All 11 markers were unlinked. These markers are being used to study the invasion routine, genetic diversity and population structure of the species P. clarkii...