Mark I C Chen

Summary

Affiliation: Tan Tock Seng Hospital
Country: Singapore

Publications

  1. pmc Trends in parameterization, economics and host behaviour in influenza pandemic modelling: a review and reporting protocol
    Luis R Carrasco
    Department of Statistics and Applied Probability, National University of Singapore, Singapore, Singapore
    Emerg Themes Epidemiol 10:3. 2013
  2. ncbi request reprint Republished paper: Populations and partnerships: insights from metapopulation and pair models into the epidemiology of gonorrhoea and other sexually transmitted infections
    Mark I Chen
    Department of Clinical Epidemiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng 308433, Singapore
    Sex Transm Infect 86:iii63-69. 2010
  3. doi request reprint Populations and partnerships: insights from metapopulation and pair models into the epidemiology of gonorrhoea and other sexually transmitted infections
    Mark I Chen
    Department of Clinical Epidemiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng 308433, Singapore
    Sex Transm Infect 86:433-9. 2010
  4. pmc Risk factors for pandemic (H1N1) 2009 virus seroconversion among hospital staff, Singapore
    Mark I C Chen
    Department of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore
    Emerg Infect Dis 16:1554-61. 2010
  5. pmc Serological response in RT-PCR confirmed H1N1-2009 influenza a by hemagglutination inhibition and virus neutralization assays: an observational study
    Mark I Chen
    Clinical Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore
    PLoS ONE 5:e12474. 2010
  6. ncbi request reprint Factors influencing infection by pandemic influenza A(H1N1)pdm09 over three epidemic waves in Singapore
    Mark I C Chen
    Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore
    Influenza Other Respir Viruses 7:1380-9. 2013
  7. doi request reprint 2009 influenza A(H1N1) seroconversion rates and risk factors among distinct adult cohorts in Singapore
    Mark I C Chen
    Tan Tock Seng Hospital, Department of Clinical Epidemiology, 11 Jalan Tan Tock Seng, Singapore, 308433
    JAMA 303:1383-91. 2010
  8. ncbi request reprint Modelling the utility of body temperature readings from primary care consults for SARS surveillance in an army medical centre
    Mark I C Chen
    Department of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore
    Ann Acad Med Singapore 35:236-41. 2006
  9. pmc Improving the clinical diagnosis of influenza--a comparative analysis of new influenza A (H1N1) cases
    Adrian K Ong
    Department of Infectious Disease, Tan Tock Seng Hospital, Singapore
    PLoS ONE 4:e8453. 2009
  10. pmc Predictors of failed attendances in a multi-specialty outpatient centre using electronic databases
    Vernon J Lee
    Department of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore
    BMC Health Serv Res 5:51. 2005

Detail Information

Publications20

  1. pmc Trends in parameterization, economics and host behaviour in influenza pandemic modelling: a review and reporting protocol
    Luis R Carrasco
    Department of Statistics and Applied Probability, National University of Singapore, Singapore, Singapore
    Emerg Themes Epidemiol 10:3. 2013
    ..The volume of influenza pandemic modelling studies has increased dramatically in the last decade. Many models incorporate now sophisticated parameterization and validation techniques, economic analyses and the behaviour of individuals...
  2. ncbi request reprint Republished paper: Populations and partnerships: insights from metapopulation and pair models into the epidemiology of gonorrhoea and other sexually transmitted infections
    Mark I Chen
    Department of Clinical Epidemiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng 308433, Singapore
    Sex Transm Infect 86:iii63-69. 2010
    ..Models of sexually transmitted infection (STI) transmission can offer insights as to why gonorrhoea and other STIs are disproportionately concentrated in epidemiologically distinct subpopulations...
  3. doi request reprint Populations and partnerships: insights from metapopulation and pair models into the epidemiology of gonorrhoea and other sexually transmitted infections
    Mark I Chen
    Department of Clinical Epidemiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng 308433, Singapore
    Sex Transm Infect 86:433-9. 2010
    ..Models of sexually transmitted infection (STI) transmission can offer insights as to why gonorrhoea and other STIs are disproportionately concentrated in epidemiologically distinct subpopulations...
  4. pmc Risk factors for pandemic (H1N1) 2009 virus seroconversion among hospital staff, Singapore
    Mark I C Chen
    Department of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore
    Emerg Infect Dis 16:1554-61. 2010
    ..5, 95% CI 0.9-6.6) and larger household size (aOR 1.2, 95% CI 1.0-1.4) were of borderline significance. Our study suggests that seroconversion was associated with occupational and nonoccupational risk factors...
  5. pmc Serological response in RT-PCR confirmed H1N1-2009 influenza a by hemagglutination inhibition and virus neutralization assays: an observational study
    Mark I Chen
    Clinical Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore
    PLoS ONE 5:e12474. 2010
    ..We describe the serological response following H1N1-2009 influenza A infections confirmed by reverse-transcriptase polymerase chain reaction (RT-PCR)...
  6. ncbi request reprint Factors influencing infection by pandemic influenza A(H1N1)pdm09 over three epidemic waves in Singapore
    Mark I C Chen
    Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore
    Influenza Other Respir Viruses 7:1380-9. 2013
    ..Previous influenza pandemics had second and on occasion third waves in many countries that were at times more severe than the initial pandemic waves...
  7. doi request reprint 2009 influenza A(H1N1) seroconversion rates and risk factors among distinct adult cohorts in Singapore
    Mark I C Chen
    Tan Tock Seng Hospital, Department of Clinical Epidemiology, 11 Jalan Tan Tock Seng, Singapore, 308433
    JAMA 303:1383-91. 2010
    ..Singapore experienced a single epidemic wave of 2009 influenza A(H1N1) with epidemic activity starting in late June 2009 and peaking in early August before subsiding within a month...
  8. ncbi request reprint Modelling the utility of body temperature readings from primary care consults for SARS surveillance in an army medical centre
    Mark I C Chen
    Department of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore
    Ann Acad Med Singapore 35:236-41. 2006
    ..We model the detection limits of a potential system based on primary care consults for the detection of an outbreak of severe acute respiratory syndrome (SARS)...
  9. pmc Improving the clinical diagnosis of influenza--a comparative analysis of new influenza A (H1N1) cases
    Adrian K Ong
    Department of Infectious Disease, Tan Tock Seng Hospital, Singapore
    PLoS ONE 4:e8453. 2009
    ..To improve the accuracy of predicting influenza infection in an outpatient setting, we undertook a comparative analysis of H1N1(2009), seasonal influenza, and persons with acute respiratory illness (ARI) in an outpatient setting...
  10. pmc Predictors of failed attendances in a multi-specialty outpatient centre using electronic databases
    Vernon J Lee
    Department of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore
    BMC Health Serv Res 5:51. 2005
    ..The objective of this study is to show the factors in an existing electronic database that affect failed appointments and to develop a predictive probability model to increase the effectiveness of interventions...
  11. pmc Accuracy and user-acceptability of HIV self-testing using an oral fluid-based HIV rapid test
    Oon Tek Ng
    Department of Infectious Disease, Tan Tock Seng Hospital, Singapore
    PLoS ONE 7:e45168. 2012
    ..We assessed the accuracy of self-testing by untrained participants compared to healthcare worker (HCW) testing, participants' ability to interpret sample results and user-acceptability of self-tests in Singapore...
  12. doi request reprint Influenza disease burden in adults by subtypes following the initial epidemic of pandemic H1N1 in Singapore
    Mar K Win
    Department of Clinical Epidemiology, Communicable Disease Centre, Tan Tock Seng Hospital, Singapore
    Influenza Other Respir Viruses 5:e563-7. 2011
    ..As at the end of the third epidemic wave in Singapore, pH1N1 cases in hospital attendances were still markedly younger than cases of H3N2 or influenza B, with little evidence for any changes in severity...
  13. ncbi request reprint Understanding the super-spreading events of SARS in Singapore
    Mark I C Chen
    Communicable Diseases Centre, Tan Tock Seng Hospital, Singapore
    Ann Acad Med Singapore 35:390-4. 2006
    ..Clinical and environmental features surrounding the index cases involved were compared with cases in non- SSEs...
  14. pmc Clinical and epidemiological predictors of transmission in Severe Acute Respiratory Syndrome (SARS)
    Mark I C Chen
    Clinical Epidemiology, Communicable Disease Centre, Tan Tock Seng Hospital, Jalan Tan Tock Seng, Singapore
    BMC Infect Dis 6:151. 2006
    ..Only a minority of probable SARS cases caused transmission. We assess if any epidemiological or clinical factors in SARS index patients were associated with increased probability of transmission...
  15. pmc Exploring if day and time of admission is associated with average length of stay among inpatients from a tertiary hospital in Singapore: an analytic study based on routine admission data
    Arul Earnest
    Department of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore
    BMC Health Serv Res 6:6. 2006
    ..We investigated if day and time of admission is associated with LOS in Tan Tock Seng Hospital (TTSH), a 1,400 bed acute care tertiary hospital serving the central and northern regions of Singapore...
  16. pmc Using autoregressive integrated moving average (ARIMA) models to predict and monitor the number of beds occupied during a SARS outbreak in a tertiary hospital in Singapore
    Arul Earnest
    Department of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore
    BMC Health Serv Res 5:36. 2005
    ..The main objective of this study is to apply autoregressive integrated moving average (ARIMA) models to make real-time predictions on the number of beds occupied in Tan Tock Seng Hospital, during the recent SARS outbreak...
  17. pmc Influenza pandemics in Singapore, a tropical, globally connected city
    Vernon J Lee
    Tan Tock Seng Hospital, Singapore
    Emerg Infect Dis 13:1052-7. 2007
    ..With the increase in travel and trade, a future pandemic may reach a globally connected city early and spread worldwide. Preparedness and surveillance plans must be developed to include the megacities of the tropical world...
  18. pmc Effectiveness of neuraminidase inhibitors for preventing staff absenteeism during pandemic influenza
    Vernon J Lee
    Tan Tock Seng Hospital, Singapore
    Emerg Infect Dis 13:449-57. 2007
    ..Small investments in treatment and prophylaxis, if adequate and timely, can reduce absenteeism among essential staff...
  19. ncbi request reprint Twentieth century influenza pandemics in Singapore
    Vernon J Lee
    Department of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore
    Ann Acad Med Singapore 37:470-6. 2008
    ..Singapore was substantially affected by three 20th Century pandemics. This study describes the course of the pandemics, and the preventive measures adopted...
  20. pmc Economic analysis of pandemic influenza vaccination strategies in Singapore
    Vernon J Lee
    Center for Health Services Research, National University of Singapore, Singapore, Singapore
    PLoS ONE 4:e7108. 2009
    ..However, few studies have evaluated the cost-effectiveness of different vaccination strategies. This paper compares the economic outcomes of vaccination compared with treatment with antiviral agents alone, in Singapore...