Tien Yin Wong

Summary

Affiliation: National University of Singapore
Country: Singapore

Publications

  1. ncbi Accuracy of diabetic retinopathy screening by trained non-physician graders using non-mydriatic fundus camera
    Mayuri Bhargava
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
    Singapore Med J 53:715-9. 2012
  2. ncbi Retinal microvasculature as a model to study the manifestations of hypertension
    Carol Yim Lui Cheung
    Singapore Eye Research Institute, 11 Third Hospital Ave, Singapore 168751, Singapore
    Hypertension 60:1094-103. 2012
  3. ncbi Language barrier and its relationship to diabetes and diabetic retinopathy
    Yingfeng Zheng
    Singapore Eye Research Institute, Singapore National Eye Centre, 11 Third Hospital Ave, 05 00, Singapore, 168751, Singapore
    BMC Public Health 12:781. 2012
  4. ncbi Aspirin for the prevention of cognitive decline in the elderly: rationale and design of a neuro-vascular imaging study (ENVIS-ion)
    Christopher M Reid
    School of Public Health and Preventive Medicine, Monash University, Melbourne Australia
    BMC Neurol 12:3. 2012
  5. ncbi Early retinal arteriolar changes and peripheral neuropathy in diabetes
    Jie Ding
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
    Diabetes Care 35:1098-104. 2012
  6. ncbi Prevalence of and risk factors for age-related macular degeneration in a multiethnic Asian cohort
    Chui Ming Gemmy Cheung
    Singapore Eye Research Institute, Singapore National Eye Centre, National University of Singapore, Singapore
    Arch Ophthalmol 130:480-6. 2012
  7. ncbi Review of key findings from the Singapore Malay Eye Study (SiMES-1)
    M Rosman
    Singapore National Eye Centre, Singapore, Singapore
    Singapore Med J 53:82-7. 2012
  8. ncbi Computer-assisted measurement of retinal vessel diameters in the Beaver Dam Eye Study: methodology, correlation between eyes, and effect of refractive errors
    Tien Yin Wong
    Department of Ophthalmology, University of Wisconsin, Madison, Wisconsin, USA
    Ophthalmology 111:1183-90. 2004
  9. ncbi Systemic associations of retinal microvascular signs: a review of recent population-based studies
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne
    Ophthalmic Physiol Opt 25:195-204. 2005
  10. ncbi Estrogen replacement therapy and retinal vascular caliber
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia
    Ophthalmology 112:553-8. 2005

Detail Information

Publications117 found, 100 shown here

  1. ncbi Accuracy of diabetic retinopathy screening by trained non-physician graders using non-mydriatic fundus camera
    Mayuri Bhargava
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
    Singapore Med J 53:715-9. 2012
    ..We compared the agreement of diabetic retinopathy (DR) assessment between trained non-physician graders (NPGs) and family physicians (FPs) in a primary healthcare setting...
  2. ncbi Retinal microvasculature as a model to study the manifestations of hypertension
    Carol Yim Lui Cheung
    Singapore Eye Research Institute, 11 Third Hospital Ave, Singapore 168751, Singapore
    Hypertension 60:1094-103. 2012
    ....
  3. ncbi Language barrier and its relationship to diabetes and diabetic retinopathy
    Yingfeng Zheng
    Singapore Eye Research Institute, Singapore National Eye Centre, 11 Third Hospital Ave, 05 00, Singapore, 168751, Singapore
    BMC Public Health 12:781. 2012
    ..We examined the associations of English proficiency with type-2 diabetes (T2DM) and diabetic retinopathy (DR) in Asian Indians living in Singapore, an urban city where English is the predominant language of communication...
  4. ncbi Aspirin for the prevention of cognitive decline in the elderly: rationale and design of a neuro-vascular imaging study (ENVIS-ion)
    Christopher M Reid
    School of Public Health and Preventive Medicine, Monash University, Melbourne Australia
    BMC Neurol 12:3. 2012
    ....
  5. ncbi Early retinal arteriolar changes and peripheral neuropathy in diabetes
    Jie Ding
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
    Diabetes Care 35:1098-104. 2012
    ..To examine the association between early retinal arteriolar abnormalities and diabetic peripheral neuropathy (DPN)...
  6. ncbi Prevalence of and risk factors for age-related macular degeneration in a multiethnic Asian cohort
    Chui Ming Gemmy Cheung
    Singapore Eye Research Institute, Singapore National Eye Centre, National University of Singapore, Singapore
    Arch Ophthalmol 130:480-6. 2012
    ..To describe the prevalence of and risk factors for age-related macular degeneration (AMD) in a multiethnic Asian cohort of Chinese, Malay, and Indian persons...
  7. ncbi Review of key findings from the Singapore Malay Eye Study (SiMES-1)
    M Rosman
    Singapore National Eye Centre, Singapore, Singapore
    Singapore Med J 53:82-7. 2012
    ..This study highlights the key epidemiological findings from the Singapore Malay Eye Study (SiMES-1)...
  8. ncbi Computer-assisted measurement of retinal vessel diameters in the Beaver Dam Eye Study: methodology, correlation between eyes, and effect of refractive errors
    Tien Yin Wong
    Department of Ophthalmology, University of Wisconsin, Madison, Wisconsin, USA
    Ophthalmology 111:1183-90. 2004
    ....
  9. ncbi Systemic associations of retinal microvascular signs: a review of recent population-based studies
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne
    Ophthalmic Physiol Opt 25:195-204. 2005
    ....
  10. ncbi Estrogen replacement therapy and retinal vascular caliber
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia
    Ophthalmology 112:553-8. 2005
    ..It is unclear if estrogen replacement therapy (ERT) has an effect on the retinal circulation. In the current study, we examine the association of ERT, female reproductive factors, and retinal vascular caliber...
  11. ncbi Risk factors of acute endophthalmitis after cataract extraction: a case-control study in Asian eyes
    T Y Wong
    Department of Ophthalmology, National University of Singapore, 10 Kent Ridge Crescent, Singapore 119260, Republic of Singapore
    Br J Ophthalmol 88:29-31. 2004
    ..To describe risk factors of acute endophthalmitis after cataract extraction in an Asian population...
  12. ncbi Retinal arteriolar diameter and risk for hypertension
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, East Melbourne Victoria, Australia
    Ann Intern Med 140:248-55. 2004
    ..Narrowing of the small arterioles has been hypothesized to contribute to the pathogenesis of hypertension, but prospective clinical data are lacking...
  13. ncbi Is retinal photography useful in the measurement of stroke risk?
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria
    Lancet Neurol 3:179-83. 2004
    ..microvascular changes, the replication of these findings in other populations and in people with other cerebrovascular disorders, and the examination of the increased accuracy of stoke-risk stratification given by retinal photography..
  14. ncbi Cardiovascular risk factors for retinal vein occlusion and arteriolar emboli: the Atherosclerosis Risk in Communities & Cardiovascular Health studies
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia
    Ophthalmology 112:540-7. 2005
    ..To examine the associations of retinal vein occlusion and arteriolar emboli with cardiovascular disease...
  15. ncbi A prospective cohort study of retinal arteriolar narrowing and mortality
    Tien Yin Wong
    Department of Ophthalmology, University of Melbourne, Victoria, Australia
    Am J Epidemiol 159:819-25. 2004
    ....
  16. ncbi Associations between the metabolic syndrome and retinal microvascular signs: the Atherosclerosis Risk In Communities study
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia
    Invest Ophthalmol Vis Sci 45:2949-54. 2004
    ..To examine the cross-sectional relationship of the metabolic syndrome (hypertension, hyperglycemia, central obesity, and dyslipidemia) and retinal microvascular abnormalities in middle-aged men and women...
  17. ncbi Lipids and diabetic retinopathy
    Laurence S Lim
    Singapore Eye Research Institute, Singapore National Eye Centre, 11 Third Hospital Ave, 05 00, 168751, Singapore
    Expert Opin Biol Ther 12:93-105. 2012
    ..Second, the pathways by which lipid-lowering therapies act in preventing the retinal complications of diabetes need to be elucidated. Last, identifying the patient profile that would benefit most from treatment is essential...
  18. ncbi Retinal vessel diameters and their associations with age and blood pressure
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, Australia
    Invest Ophthalmol Vis Sci 44:4644-50. 2003
    ..To describe the cross-sectional relationship between retinal arteriolar and venular diameters with age and blood pressure...
  19. ncbi Retinal microvascular changes and MRI signs of cerebral atrophy in healthy, middle-aged people
    T Y Wong
    Singapore National Eye Center and National University of Singapore
    Neurology 61:806-11. 2003
    ..To examine the relation of retinal microvascular abnormalities and MRI signs of cerebral atrophy in healthy middle-aged people...
  20. ncbi Retinopathy and risk of congestive heart failure
    Tien Y Wong
    Centre for Eye Research Australia, University of Melbourne, Victoria, Australia
    JAMA 293:63-9. 2005
    ..The pathogenesis of CHF is uncertain, but microvascular disease has been hypothesized as a possible factor...
  21. ncbi Retinal arteriolar emboli: epidemiology and risk of stroke
    Tien Yin Wong
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin, USA
    Curr Opin Ophthalmol 13:142-6. 2002
    ..Whether carotid ultrasound and other vascular imaging studies should be performed routinely for all patients with asymptomatic retinal emboli remains uncertain...
  22. ncbi Retinal arteriolar narrowing and risk of diabetes mellitus in middle-aged persons
    Tien Yin Wong
    Department of Ophthalmology, National University of Singapore, 10 Kent Ridge Crescent, Singapore 119260
    JAMA 287:2528-33. 2002
    ..Microvascular processes have been hypothesized to play a role in the pathogenesis of type 2 diabetes mellitus, but prospective clinical data regarding this hypothesis are unavailable...
  23. ncbi Retinal microvascular abnormalities and cognitive impairment in middle-aged persons: the Atherosclerosis Risk in Communities Study
    Tien Yin Wong
    Department of Ophthalmology, University of Wisconsin, Madison, USA
    Stroke 33:1487-92. 2002
    ..Here, we examine the relation of retinal microvascular abnormalities with cognitive function in middle-aged persons free of stroke...
  24. ncbi Cerebral white matter lesions, retinopathy, and incident clinical stroke
    Tien Yin Wong
    Department of Ophthalmology, University of Wisconsin, Madison, USA
    JAMA 288:67-74. 2002
    ..White matter lesions (WMLs) detected on cerebral imaging scans have been hypothesized to have a microvascular etiology and to precede the development of clinical stroke. However, few clinical data are available to support these hypotheses...
  25. ncbi Refractive errors and 10-year incidence of age-related maculopathy
    Tien Yin Wong
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin, USA
    Invest Ophthalmol Vis Sci 43:2869-73. 2002
    ..To describe the relationship of refractive errors to the 10-year incidence of age-related maculopathy (ARM) in a defined white population...
  26. ncbi Is early age-related maculopathy related to cognitive function? The Atherosclerosis Risk in Communities Study
    Tien Yin Wong
    Singapore Eye Research Institute and Department of Ophthalmology, National University of Singapore, Singapore
    Am J Ophthalmol 134:828-35. 2002
    ..We describe the association between cognitive function and ARM in middle-aged persons...
  27. ncbi Retinal microvascular abnormalities and 10-year cardiovascular mortality: a population-based case-control study
    Tien Yin Wong
    Singapore National Eye Center and National University of Singapore, Singapore, Republic of Singapore
    Ophthalmology 110:933-40. 2003
    ..Retinal microvascular abnormalities reflect persistent arteriolar damage from hypertension and independently predict stroke. We examined their associations with long-term cardiovascular mortality...
  28. ncbi The prevalence and risk factors of retinal microvascular abnormalities in older persons: The Cardiovascular Health Study
    Tien Yin Wong
    Singapore Eye Research Institute, Singapore, Republic of Singapore
    Ophthalmology 110:658-66. 2003
    ..To describe the prevalence of retinal microvascular characteristics and their associations with atherosclerosis in elderly, nondiabetic persons...
  29. ncbi Refractive errors, axial ocular dimensions, and age-related cataracts: the Tanjong Pagar survey
    Tien Yin Wong
    Department of Ophthalmology, National University of Singapore, Singapore
    Invest Ophthalmol Vis Sci 44:1479-85. 2003
    ..To describe the relationship of refractive errors and axial ocular dimensions and age-related cataract...
  30. ncbi Racial differences in the prevalence of hypertensive retinopathy
    Tien Yin Wong
    Department of Ophthalmology, Singapore National Eye Center and National University of Singapore
    Hypertension 41:1086-91. 2003
    ....
  31. ncbi Retinal arteriolar narrowing and left ventricular remodeling: the multi-ethnic study of atherosclerosis
    Ning Cheung
    Centre for Eye Research Australia, University of Melbourne, Victoria, Australia
    J Am Coll Cardiol 50:48-55. 2007
    ..This study sought to examine the relationships of retinal vascular signs with left ventricular (LV) mass, volume, and concentric remodeling...
  32. ncbi Visual impairment, age-related eye diseases, and cognitive function: the Singapore Malay Eye study
    Shin Yeu Ong
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
    Arch Ophthalmol 130:895-900. 2012
    ..To describe the associations of visual impairment and major age-related eye diseases with cognitive function in an older Asian population...
  33. ncbi Distribution and determinants of ocular biometric parameters in an Asian population: the Singapore Malay eye study
    Laurence Shen Lim
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
    Invest Ophthalmol Vis Sci 51:103-9. 2010
    ..To examine the distribution and systemic determinants of ocular biometry as measured using partial laser interferometry in an adult Asian population...
  34. ncbi Evidence of retinal vascular narrowing in glaucomatous eyes in an Asian population
    Nishani Amerasinghe
    Singapore National Eye Centre, Singapore
    Invest Ophthalmol Vis Sci 49:5397-402. 2008
    ..To examine the relationship between retinal vascular caliber and glaucoma in an Asian population...
  35. ncbi BMI and retinal vascular caliber in children
    Ning Cheung
    Centre for Eye Research Australia, University of Melbourne, 32 Gisborne Street, Victoria 3002, Australia
    Obesity (Silver Spring) 15:209-15. 2007
    ..In adult populations, changes in retinal vascular caliber have been linked with obesity and metabolic syndrome. We examined the association of BMI and weight with retinal vascular caliber in children...
  36. ncbi Differential associations of myopia with major age-related eye diseases: the Singapore Indian Eye Study
    Chen Wei Pan
    Saw Swee Hock School of Public Health, National University of Singapore, Singapore
    Ophthalmology 120:284-91. 2013
    ..To determine the associations of myopia and axial length (AL) with major age-related eye diseases, including age-related macular degeneration (AMD), diabetic retinopathy (DR), age-related cataract, and primary open-angle glaucoma (POAG)...
  37. ncbi Effect of blood pressure on the retinal vasculature in a multi-ethnic Asian population
    V Swetha E Jeganathan
    Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia
    Hypertens Res 32:975-82. 2009
    ..0001); furthermore, the magnitude of this effect was similar across the three racial/ethnic groups. The effect of blood pressure on the retinal vasculature was similar across three major racial/ethnic groups in Asia...
  38. ncbi Relationship of axial length and retinal vascular caliber in children
    Ning Cheung
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia
    Am J Ophthalmol 144:658-662. 2007
    ..In this study, we re-examined this relationship in a cohort of children, while controlling for the effects of ocular magnification...
  39. ncbi The relationship of body fatness indices and retinal vascular caliber in children
    Ling Jun Li
    Department of Epidemiology and Public Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Int J Pediatr Obes 6:267-74. 2011
    ..To examine the association between body fatness indices and retinal vascular calibre in Singapore Chinese children...
  40. ncbi Smoking, socioeconomic factors, and age-related cataract: The Singapore Malay Eye study
    Renyi Wu
    Singapore Eye Research Institute, Singapore
    Arch Ophthalmol 128:1029-35. 2010
    ..To describe the relationship of smoking, sex, and socioeconomic factors with age-related cataract in Malay adults in Singapore...
  41. ncbi Subclinical atherosclerotic cardiovascular disease and early age-related macular degeneration in a multiracial cohort: the Multiethnic Study of Atherosclerosis
    Ronald Klein
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison 53726 2397, USA
    Arch Ophthalmol 125:534-43. 2007
    ..To investigate the relationship of subclinical atherosclerotic cardiovascular disease (CVD) and its risk factors with age-related macular degeneration (AMD) in the Multiethnic Study of Atherosclerosis...
  42. ncbi Are myopic eyes less likely to have diabetic retinopathy?
    Laurence Shen Lim
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Republic of Singapore
    Ophthalmology 117:524-30. 2010
    ..Eyes with myopia may be less likely to develop diabetic retinopathy (DR). The relationship between refractive error, ocular biometry, and DR therefore was investigated...
  43. ncbi Prevalence of refractive error in Singaporean Chinese children: the strabismus, amblyopia, and refractive error in young Singaporean Children (STARS) study
    Mohamed Dirani
    Singapore Eye Research Institute, Singapore
    Invest Ophthalmol Vis Sci 51:1348-55. 2010
    ..To determine the prevalence of refractive error types in Singaporean Chinese children aged 6 to 72 months...
  44. ncbi Retinal vascular tortuosity, blood pressure, and cardiovascular risk factors
    Carol Yim Lui Cheung
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
    Ophthalmology 118:812-8. 2011
    ..To examine the relationship of retinal vascular tortuosity to age, blood pressure, and other cardiovascular risk factors...
  45. ncbi Retinal arteriolar narrowing and risk of coronary heart disease in men and women. The Atherosclerosis Risk in Communities Study
    Tien Yin Wong
    Department of Ophthalmology, National University of Singapore, 10 Kent Ridge Crescent, Singapore 119260
    JAMA 287:1153-9. 2002
    ..Microvascular processes have been hypothesized to play a greater role in the development of coronary heart disease (CHD) in women than in men; however, prospective clinical data are limited...
  46. ncbi Relationship of retinal vascular caliber with diabetes and retinopathy: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Thanh Tan Nguyen
    Centre for Eye Research Australia, University of Melbourne, 32 Gisborne Street, Victoria 3002, Australia
    Diabetes Care 31:544-9. 2008
    ..To examine the relationship of retinal vascular caliber with diabetes, glycemia, and diabetic retinopathy...
  47. ncbi Myopia and cognitive dysfunction: the singapore malay eye study
    Shin Yeu Ong
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
    Invest Ophthalmol Vis Sci 54:799-803. 2013
    ..To investigate a possible relationship between refractive error and cognitive function...
  48. ncbi The association between socioeconomic status and overweight/obesity in a Malay population in Singapore
    Charumathi Sabanayagam
    Department of Community, Occupational, and Family Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Asia Pac J Public Health 21:487-96. 2009
    ..05 for all SES variables). Lower SES was positively associated with overweight/obesity in Malay women, and the association was in the opposite direction in Malay men...
  49. ncbi Differential association of retinal arteriolar and venular caliber with diabetes and retinopathy
    Andrew S H Tsai
    Singapore Eye Research Institute, Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore 168751, Singapore
    Diabetes Res Clin Pract 94:291-8. 2011
    ..To describe the relationship of retinal arteriolar and venular caliber with diabetes, retinopathy and hyperglycemia, in an Asian Indian population...
  50. ncbi Diabetic retinopathy in a multi-ethnic cohort in the United States
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, 32 Gisborne Street, Melbourne, Victoria 3002, Australia
    Am J Ophthalmol 141:446-455. 2006
    ..To describe the prevalence and risk factors of diabetic retinopathy in a multi-ethnic US population of whites, blacks, hispanics, and chinese...
  51. ncbi Prevalence and risk factors of retinopathy in an Asian population without diabetes: the Singapore Malay Eye Study
    V Swetha E Jeganathan
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia
    Arch Ophthalmol 128:40-5. 2010
    ..To describe the prevalence and risk factors of retinopathy in an Asian population without diabetes...
  52. ncbi FTO variants are associated with obesity in the Chinese and Malay populations in Singapore
    Jonathan T Tan
    Center for Molecular Epidemiology, National University of Singapore, Singapore, Singapore
    Diabetes 57:2851-7. 2008
    ..The aim of this study was to examine the effects of FTO variants on obesity and type 2 diabetes in Southeast Asian populations...
  53. ncbi Traditional and novel cardiovascular risk factors for retinal vein occlusion: the multiethnic study of atherosclerosis
    Ning Cheung
    Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, University of Melbourne, East Melbourne, Victoria, Australia
    Invest Ophthalmol Vis Sci 49:4297-302. 2008
    ..To describe the prevalence of retinal vein occlusion (RVO) and its association with cardiovascular, inflammatory, and hematologic risk factors in a multiethnic cohort...
  54. ncbi Influence of intraocular pressure on retinal vascular caliber measurements in children
    Kristin de Haseth
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia
    Am J Ophthalmol 143:1040-2. 2007
    ..To determine whether intraocular pressure (IOP) influences retinal vascular caliber in young children, in order to provide a better understanding of its physiological determinants...
  55. ncbi Prevalence of diabetes mellitus, glycemic control, and associated factors in a Malay population in Singapore
    Charumathi Sabanayagam
    Department of Community, Occupational, and Family Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Asia Pac J Public Health 21:385-98. 2009
    ..Nearly 1 in 5 middle-aged Malay adults living in a developed Asian society had diabetes mellitus and a substantial proportion had suboptimal glycemic control...
  56. ncbi Quantitative retinal venular caliber and risk of cardiovascular disease in older persons: the cardiovascular health study
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, Victoria, Australia
    Arch Intern Med 166:2388-94. 2006
    ..Small vessel disease may contribute to the risk of cardiovascular disease in older persons. We describe the relation of retinal vascular caliber to incident coronary heart disease (CHD) and stroke in elderly persons...
  57. ncbi Distribution and associations of retinal vascular caliber with ethnicity, gender, and birth parameters in young children
    Ning Cheung
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia
    Invest Ophthalmol Vis Sci 48:1018-24. 2007
    ..To describe the distribution of retinal vascular calibers and their associations with ethnicity, gender, and birth parameters in children...
  58. ncbi Corneal biomechanical properties and retinal vascular caliber in children
    Laurence Lim
    Singapore Eye Research Institute, Singapore
    Invest Ophthalmol Vis Sci 50:121-5. 2009
    ..To examine the relationship between corneal biomechanical properties and retinal vascular caliber in Singaporean children in a cross-sectional study of 257 healthy subjects from the Singapore Cohort Study of Risk Factors for Myopia...
  59. ncbi Retinal vascular fractal dimension and its relationship with cardiovascular and ocular risk factors
    Carol Y Cheung
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
    Am J Ophthalmol 154:663-674.e1. 2012
    ..To examine the influence of a range of cardiovascular risk factors and ocular conditions on retinal vascular fractal dimension in the Singapore Malay Eye Study...
  60. ncbi Peripheral artery disease and glaucoma: the singapore malay eye study
    V Swetha E Jeganathan
    Centre for Eye Research Australia, University of Melbourne, Victoria, Australia
    Arch Ophthalmol 127:888-93. 2009
    ..To examine the relationship between peripheral artery disease (PAD) and glaucoma...
  61. ncbi Influence of refractive error on optic disc topographic parameters: the singapore malay eye study
    Ren Yi Wu
    Singapore Eye Research Institute and Singapore National Eye Center, Singapore, Republic of Singapore
    Am J Ophthalmol 152:81-6. 2011
    ..To examine the relationship between refractive error and optic disc topographic parameters and retinal nerve fiber layer (RNFL) thickness...
  62. ncbi Association of narrow angles with anterior chamber area and volume measured with anterior-segment optical coherence tomography
    Ren Yi Wu
    Singapore National Eye Centre, 11 Third Hospital Ave, Singapore 168751
    Arch Ophthalmol 129:569-74. 2011
    ..To describe the measurement of anterior chamber area and anterior chamber volume by anterior-segment optical coherence tomography and to investigate the association of these parameters with the presence of narrow angles...
  63. ncbi A new method to measure peripheral retinal vascular caliber over an extended area
    Carol Yim Lui Cheung
    Singapore Eye Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Microcirculation 17:495-503. 2010
    ..To describe a new computer-assisted method to measure retinal vascular caliber over an extended area of the fundus...
  64. ncbi Determinants of angle closure in older Singaporeans
    Raghavan Lavanya
    Department of Glaucoma, Singapore National Eye Center and Eye Research Institute, 11 Third Hospital Ave, Singapore 168751
    Arch Ophthalmol 126:686-91. 2008
    ..To investigate systemic and ocular risk factors for angle closure (AC) in older Singaporeans and to determine if these risk factors are different in men vs women and in Chinese vs non-Chinese persons...
  65. ncbi Blood pressure and retinal microvascular characteristics during pregnancy: Growing Up in Singapore Towards Healthy Outcomes (GUSTO) Study
    Ling Jun Li
    Saw Swee Hock School of Public Health, National University of Singapore, Singapore
    Hypertension 60:223-30. 2012
    ..Elevated blood pressure is associated with a range of retinal arteriolar changes in pregnant women, providing evidence for an impact of blood pressure on the microcirculation during pregnancy...
  66. ncbi Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism
    Qiao Fan
    School of Public Health, National University of Singapore, Singapore, Singapore
    PLoS Genet 7:e1002402. 2011
    ..This highlights the potential role of variants in PDGFRA in the genetic etiology of corneal astigmatism across diverse Asian populations...
  67. ncbi Prevalence and risk factors for refractive errors in Indians: the Singapore Indian Eye Study (SINDI)
    Chen Wei Pan
    Department of Epidemiology and Public Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Invest Ophthalmol Vis Sci 52:3166-73. 2011
    ..To determine the prevalence and risk factors for refractive errors in middle-aged to elderly Singaporeans of Indian ethnicity...
  68. ncbi Literacy is an independent risk factor for vision impairment and poor visual functioning
    Yingfeng Zheng
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
    Invest Ophthalmol Vis Sci 52:7634-9. 2011
    ..The authors therefore investigated the independent contribution of limited literacy on visual impairment and visual function in a large eye survey in Singapore...
  69. ncbi Relation of age-related cataract with obesity and obesity genes in an Asian population
    Laurence S Lim
    Singapore Eye Research Institute, Singapore
    Am J Epidemiol 169:1267-74. 2009
    ..30, 95% CI: 1.08, 1.55). These results do not support a causal association between obesity and cortical or PSC cataract. The FTO gene may be involved in the pathogenesis of nuclear cataract...
  70. ncbi Retinal microvascular caliber and chronic kidney disease in an Asian population
    Charumathi Sabanayagam
    Department of Community, Occupational, and Family Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Am J Epidemiol 169:625-32. 2009
    ..Retinal venular diameter was not associated with chronic kidney disease. These data suggest that retinal arteriolar narrowing is associated with chronic kidney disease, independent of diabetes and hypertension...
  71. ncbi Age-related macular degeneration and risk for stroke
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, Australia
    Ann Intern Med 145:98-106. 2006
    ..Age-related macular degeneration (AMD) affects 7 million persons 40 years of age and older in the United States. Risk factors for the disease are similar to those for stroke...
  72. ncbi Corneal arcus is a sign of cardiovascular disease, even in low-risk persons
    Marcus Ang
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Republic of Singapore
    Am J Ophthalmol 152:864-71.e1. 2011
    ..To examine the association of corneal arcus to cardiovascular disease (CVD) in an adult, ethnic Indian population...
  73. ncbi C-reactive protein, body mass index, and diabetic retinopathy
    Laurence Shen Lim
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
    Invest Ophthalmol Vis Sci 51:4458-63. 2010
    ..The purpose of this study was to determine the relationship between CRP, BMI, and existing DR...
  74. ncbi Prevalence of age-related macular degeneration in 4 racial/ethnic groups in the multi-ethnic study of atherosclerosis
    Ronald Klein
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin 53726 2336, USA
    Ophthalmology 113:373-80. 2006
    ..To describe the prevalence of age-related macular degeneration (AMD) in 4 racial/ethnic groups (white, black, Hispanic, and Chinese) that participated in the second examination of the Multi-ethnic Study of Atherosclerosis (MESA)...
  75. ncbi Retinal arteriolar caliber predicts incident retinopathy: the Australian Diabetes, Obesity and Lifestyle (AusDiab) study
    Sophie Louise Rogers
    Centre for Eye Research, University of Melbourne, 32 Gisborne St, Victoria 3002, Australia
    Diabetes Care 31:761-3. 2008
    ..Venular caliber did not predict incident retinopathy. Our findings suggest that retinal arteriolar dilatation is a specific sign of diabetic microvascular dysfunction and may be a preclinical marker of diabetic retinopathy...
  76. ncbi Cardiovascular risk factors, inflammation, and corneal arcus: the singapore malay eye study
    Renyi Wu
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
    Am J Ophthalmol 150:581-587.e1. 2010
    ..To examine the relationship of corneal arcus with cardiovascular risk factors and inflammation in Malay adults living in Singapore...
  77. ncbi Relationship of ocular biometry and retinal vascular caliber in preschoolers
    Ling Jun Li
    Department of Epidemiology and Public Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Invest Ophthalmol Vis Sci 52:9561-6. 2011
    ..To systematically examine the association between ocular biometry and retinal vascular caliber in Singapore Chinese preschoolers aged 48 to 72 months...
  78. ncbi Relationship of retinal vascular caliber with optic disc diameter in children
    Ning Cheung
    Centre for Eye Research Australia, University of Melbourne, Victoria, Australia
    Invest Ophthalmol Vis Sci 48:4945-8. 2007
    ..To describe the relationships of retinal vascular caliber to optic disc diameter in children...
  79. ncbi C-reactive protein and age-related macular degeneration and cataract: the singapore malay eye study
    Pui Yi Boey
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
    Invest Ophthalmol Vis Sci 51:1880-5. 2010
    ..In persons without diabetes, higher CRP was associated with AMD. These data suggest only a weak link between systemic inflammation and AMD and cataract in Asian people...
  80. ncbi Effect of corneal arcus on central corneal thickness, intraocular pressure, and primary open-angle glaucoma: the Singapore Malay Eye Study
    Renyi Wu
    Singapore Eye Research Institute, Singapore
    Arch Ophthalmol 128:1455-61. 2010
    ..To examine the association of corneal arcus with central corneal thickness (CCT), intraocular pressure (IOP), and the prevalence of primary open-angle glaucoma...
  81. ncbi Are obesity and anthropometry risk factors for diabetic retinopathy? The diabetes management project
    Mohamed Dirani
    Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia
    Invest Ophthalmol Vis Sci 52:4416-21. 2011
    ..To investigate the relationship between anthropometric parameters and diabetic retinopathy (DR) in adults with diabetes...
  82. ncbi Fractal analysis of retinal microvasculature and coronary heart disease mortality
    Gerald Liew
    Centre for Vision Research, Department of Ophthalmology, University of Sydney, Sydney, NSW, Australia
    Eur Heart J 32:422-9. 2011
    ..Fractal analysis provides a global assessment of vascular network architecture. We examined the relationship of retinal vascular fractal dimension (D(f)) with coronary heart disease (CHD) mortality...
  83. ncbi Is there a clear threshold for fasting plasma glucose that differentiates between those with and without neuropathy and chronic kidney disease?: the Singapore Prospective Study Program
    Ei Ei Khaing Nang
    Department of Community, Occupational and Family Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Am J Epidemiol 169:1454-62. 2009
    ..Ascertaining these individuals may require development and application of novel screening strategies...
  84. ncbi Hypertensive retinopathy signs as risk indicators of cardiovascular morbidity and mortality
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, 32 Gisborne Street, East Melbourne 3002, Australia
    Br Med Bull 73:57-70. 2005
    ..These data support the concept that an assessment of retinal vascular changes may provide further information for vascular risk stratification in persons with hypertension...
  85. ncbi Retinal vascular caliber, cardiovascular risk factors, and inflammation: the multi-ethnic study of atherosclerosis (MESA)
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia
    Invest Ophthalmol Vis Sci 47:2341-50. 2006
    ..To describe the relationship of retinal arteriolar and venular caliber with cardiovascular risk factors, including inflammatory biomarkers, in a multiethnic population of whites, blacks, Hispanics, and Chinese...
  86. ncbi Revised formulas for summarizing retinal vessel diameters
    Michael D Knudtson
    Department of Ophthalmology, University of Wisconsin, Madison, WI 53726, USA
    Curr Eye Res 27:143-9. 2003
    ....
  87. ncbi Does refractive error influence the association of blood pressure and retinal vessel diameters? The Blue Mountains Eye Study
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, East Melbourne
    Am J Ophthalmol 137:1050-5. 2004
    ..To determine if refractive errors influence the association of blood pressure and retinal vessel diameters...
  88. ncbi Systemic markers of inflammation, endothelial dysfunction, and age-related maculopathy
    Ronald Klein
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School Madison, 53726, USA
    Am J Ophthalmol 140:35-44. 2005
    ..To examine the association of systemic markers of inflammatory disease and endothelial dysfunction with age-related maculopathy (ARM)...
  89. ncbi Early age-related macular degeneration, cognitive function, and dementia: the Cardiovascular Health Study
    Michelle L Baker
    Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, Australia
    Arch Ophthalmol 127:667-73. 2009
    ..To describe the association of cognitive function and dementia with early age-related macular degeneration (AMD) in older individuals...
  90. ncbi Ocular component growth curves among Singaporean children with different refractive error status
    Hwee Bee Wong
    Health Services Research and Evaluation Division, Ministry of Health, Singapore, Republic of Singapore
    Invest Ophthalmol Vis Sci 51:1341-7. 2010
    ..To describe and compare ocular component growth curves among different refractive error groups in Singaporean children...
  91. ncbi Prevalence and risk factors for refractive errors in the Singapore Malay Eye Survey
    Seang Mei Saw
    Department of Community, Occupational and Family Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Ophthalmology 115:1713-9. 2008
    ..To describe the prevalence and risk factors for myopia and other refractive errors in an urban Malay population in Singapore...
  92. ncbi Retinal vessel caliber and peripheral neuropathy in diabetic participants
    Charumathi Sabanayagam
    Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Microcirculation 17:297-302. 2010
    ..Retinal vascular caliber changes predict diabetic microvascular complications such as retinopathy, and nephropathy. However, the association between retinal vasculature and peripheral neuropathy is not well studied...
  93. ncbi C-reactive protein and retinal microvascular caliber in a multiethnic asian population
    Carol Yim-Lui Cheung
    Singapore Eye Research Institute, 11 Third Hospital Avenue, Singapore, Singapore
    Am J Epidemiol 171:206-13. 2010
    ....
  94. ncbi Retinal microvascular abnormalities and age-related hearing loss: the Blue Mountains hearing study
    Gerald Liew
    Department of Ophthalmology, Centre for Vision Research, University of Sydney, Australia
    Ear Hear 28:394-401. 2007
    ..Microvascular disease may contribute to hearing loss. We tested this hypothesis by examining the relation of retinal microvascular abnormalities and hearing loss...
  95. ncbi Measurement of retinal vascular caliber: issues and alternatives to using the arteriole to venule ratio
    Gerald Liew
    Centre for Vision Research, Department of Ophthalmology, Westmead Millennium Instiute, University of Sydney, Sydney, Australia
    Invest Ophthalmol Vis Sci 48:52-7. 2007
    ....
  96. ncbi Relationship of retinal vascular tortuosity with the neuroretinal rim: the singapore malay eye study
    Victor Koh
    Singapore Eye Research Institute, Singapore National Eye Center, Singapore
    Invest Ophthalmol Vis Sci 51:3736-41. 2010
    ..Straighter retinal vessels were significantly associated with a thinning neuroretinal rim. These findings may provide additional insights into the geometric retinal vascular changes seen in early glaucomatous optic neuropathy...
  97. ncbi Prospective cohort study of retinal vessel diameters and risk of hypertension
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, Victoria 3002, Australia
    BMJ 329:79. 2004
    ..To examine the relation between diameters of the retinal arterioles and 10 year incidence of hypertension...
  98. ncbi Retinal microvascular signs, cognitive function, and dementia in older persons: the Cardiovascular Health Study
    Michelle L Baker
    Centre for Eye Research Australia, University of Melbourne, East Melbourne Victoria, Australia
    Stroke 38:2041-7. 2007
    ..Cerebral microvascular disease may be a risk factor for the development of dementia in elderly persons. We describe the association of retinal microvascular signs with cognitive function and dementia among older individuals...
  99. ncbi A cohort study of incident myopia in Singaporean children
    Seang Mei Saw
    Department of Community, Occupational, and Family Medicine, National University of Singapore, Singapore
    Invest Ophthalmol Vis Sci 47:1839-44. 2006
    ..To determine the risk factors of incident myopia in a school-based cohort study in Singaporean children...
  100. ncbi Association between body mass index and chronic kidney disease in men and women: population-based study of Malay adults in Singapore
    Anoop Shankar
    Department of Community, Occupational, and Family Medicine, Singapore General Hospital, Singapore
    Nephrol Dial Transplant 23:1910-8. 2008
    ..In this context, we examined the relationship between BMI and CKD, by gender, in a study of Malay adults from Singapore...
  101. ncbi Risk factors for contact lens-related fusarium keratitis: a case-control study in Singapore
    Seang Mei Saw
    Department of Community, Occupational, and Family Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 16 Medical Drive, Singapore 117597, Republic of Singapore
    Arch Ophthalmol 125:611-7. 2007
    ..To evaluate the specific contact lens-related or other factors that may contribute to the outbreak of Fusarium keratitis...