Tien Yin Wong


Affiliation: National University of Singapore
Country: Singapore


  1. Wong T, Ferreira A, Hughes R, Carter G, Mitchell P. Epidemiology and disease burden of pathologic myopia and myopic choroidal neovascularization: an evidence-based systematic review. Am J Ophthalmol. 2014;157:9-25.e12 pubmed publisher
    ..Of these, a substantial proportion of patients develop myopic CNV, which mostly causes a significant progressive decrease in visual acuity. This condition should therefore be a target for new treatment strategies. ..
  2. Nusinovici S, Sabanayagam C, Teo B, Tan G, Wong T. Vision Impairment in CKD Patients: Epidemiology, Mechanisms, Differential Diagnoses, and Prevention. Am J Kidney Dis. 2019;: pubmed publisher
    ..Interdisciplinary collaboration between nephrologists and ophthalmologists will ensure enhanced and appropriate management of patients with CKD. ..
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    Wong T, Foster P, Johnson G, Seah S. Refractive errors, axial ocular dimensions, and age-related cataracts: the Tanjong Pagar survey. Invest Ophthalmol Vis Sci. 2003;44:1479-85 pubmed
    ..Posterior subcapsular cataract is also associated with deeper anterior chamber, thinner lens, and longer vitreous chamber, with vitreous chamber depth explaining most of the association between posterior subcapsular cataract and myopia. ..
  4. Sabanayagam C, Banu R, Chee M, Lee R, Wang Y, Tan G, et al. Incidence and progression of diabetic retinopathy: a systematic review. Lancet Diabetes Endocrinol. 2019;7:140-149 pubmed publisher
    ..Our data is useful for conceptualisation and development of major public health strategies such as screening programmes for diabetic retinopathy. ..
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    Wong T, Mosley T, Klein R, Klein B, Sharrett A, Couper D, et al. Retinal microvascular changes and MRI signs of cerebral atrophy in healthy, middle-aged people. Neurology. 2003;61:806-11 pubmed
    ..This finding is compatible with the hypothesis that microvascular characteristics may influence the development of cerebral atrophic changes. ..
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    Wong T, Knudtson M, Klein R, Klein B, Hubbard L. A prospective cohort study of retinal arteriolar narrowing and mortality. Am J Epidemiol. 2004;159:819-25 pubmed
  7. Sabanayagam C, Lye W, Klein R, Klein B, Cotch M, Wang J, et al. Retinal microvascular calibre and risk of diabetes mellitus: a systematic review and participant-level meta-analysis. Diabetologia. 2015;58:2476-85 pubmed publisher
    ..Knowledge of pathological mechanisms underlying wider retinal venule may provide further insights concerning microvascular alterations in diabetes. ..
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    Wong T, Klein R, Sharrett A, Schmidt M, Pankow J, Couper D, et al. Retinal arteriolar narrowing and risk of diabetes mellitus in middle-aged persons. JAMA. 2002;287:2528-33 pubmed
    ..Retinal arteriolar narrowing is independently associated with risk of diabetes, supporting a microvascular role in the development of clinical diabetes. ..
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    Wong T, McIntosh R. Systemic associations of retinal microvascular signs: a review of recent population-based studies. Ophthalmic Physiol Opt. 2005;25:195-204 pubmed

More Information


  1. Wong T, Scott I. Clinical practice. Retinal-vein occlusion. N Engl J Med. 2010;363:2135-44 pubmed publisher
  2. Lim L, Cheung C, Mitchell P, Wong T. Emerging evidence concerning systemic safety of anti-VEGF agents--should ophthalmologists be concerned?. Am J Ophthalmol. 2011;152:329-331 pubmed publisher
  3. Lim L, Cheung C, Sabanayagam C, Lim S, Tai E, Huang L, et al. Structural changes in the retinal microvasculature and renal function. Invest Ophthalmol Vis Sci. 2013;54:2970-6 pubmed publisher
    ..Quantitative changes of the retinal vascular geometry and qualitative changes in the vessel architecture are associated with markers of renal dysfunction and damage. ..
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    Wong T, Klein R, Klein B, Meuer S, Hubbard L. Retinal vessel diameters and their associations with age and blood pressure. Invest Ophthalmol Vis Sci. 2003;44:4644-50 pubmed
    ..To describe the cross-sectional relationship between retinal arteriolar and venular diameters with age and blood pressure...
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    Wong T, Larsen E, Klein R, Mitchell P, Couper D, Klein B, et al. Cardiovascular risk factors for retinal vein occlusion and arteriolar emboli: the Atherosclerosis Risk in Communities & Cardiovascular Health studies. Ophthalmology. 2005;112:540-7 pubmed
    ..To examine the associations of retinal vein occlusion and arteriolar emboli with cardiovascular disease...