Research Topics
Genomes and GenesSpecies | Aileen WeeSummaryAffiliation: National University of Singapore Country: Singapore Publications
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Detail Information
Publications
Highly well differentiated hepatocellular carcinoma and benign hepatocellular lesions. Can they be distinguished on fine needle aspiration biopsy?Aileen Wee
Department of Pathology, National University Hospital, National University of Singapore, Singapore, Republic of Singapore
Acta Cytol 47:16-26. 2003..To determine whether highly well differentiated hepatocellular carcinoma can be distinguished from benign hepatocellular lesions on fine needle aspiration biopsy (FNAB)...
Diagnostic utility of immunohistochemistry in hepatocellular carcinoma, its variants and their mimicsAileen Wee
Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, National University Hospital, 5 Lower Kent Ridge Road, Singapore, 119074, Singapore
Appl Immunohistochem Mol Morphol 14:266-72. 2006..AFP, pCEA/CD10, and CD34 are useful for ascertainment of malignancy in hepatocellular nodules; HepPar1 and cytokeratins to be included if histogenesis is the issue. IHC results should be interpreted in the larger context of the case...
alpha-Fetoprotein-producing liver carcinomas of primary extrahepatic originAileen Wee
Department of Pathology, National University Hospital, National University of Singapore, Singapore, Republic of Singapore
Acta Cytol 47:799-808. 2003..This would create diagnostic problems in hepatic fine needle aspiration biopsies (FNABs) from patients with elevated serum AFP. Apart from HCC, its variants and germ cell tumors, one must consider metastatic AFP-producing carcinomas...
A randomized controlled pilot study of Pentoxifylline in patients with non-alcoholic steatohepatitis (NASH)Yin Mei Lee
Department of Gastroenterology Hepatology, National University Hospital, 5 Lower Kent Ridge Road, Singapore, 119074, Singapore
Hepatol Int 2:196-201. 2008..Tumor necrosis factor-alpha (TNF-alpha) is implicated in non-alcoholic steatohepatitis (NASH). Pentoxifylline inhibits TNF-alpha. We wanted to evaluate the efficacy of Pentoxifylline on NASH patients...
Prevalence and clinical associations of posttransplant fatty liver diseaseLee Guan Lim
Department of Gastroenterology and Hepatology, National University Hospital, Singapore, Singapore
Liver Int 27:76-80. 2007..The literature on posttransplant NAFLD is limited. We aimed to study the prevalence of posttransplant NAFLD in patients transplanted for non-NAFLD-related liver diseases...
Primary biliary cirrhosis in Singapore: evaluation of demography, prognostic factors and natural course in a multi-ethnic populationReuben Km Wong
Department of Gastroenterology and Hepatology, National University Hospital, Singapore
J Gastroenterol Hepatol 23:599-605. 2008..Primary biliary cirrhosis (PBC) is infrequent in Asians. Among Asian patients with PBC, information on natural course is scarce. The aim of this study was to study the clinical course and prognosticators among Asians with PBC...
A randomized, placebo-controlled trial of thymosin-alpha1 and lymphoblastoid interferon for HBeAg-positive chronic hepatitis BSeng Gee Lim
Department of Gastroenterology and Hepatology, National University Hospital, Singapore
Antivir Ther 11:245-53. 2006..8% improvement in HBeAg loss rates using combination therapy over interferon monotherapy. This could clinically indicate a potential important difference that would need confirmation in subsequent trials...
Primary malignant melanoma of the esophagus with multiple esophageal lesionsKhek Yu Ho
Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
Nat Clin Pract Gastroenterol Hepatol 4:171-4. 2007..A 48-year-old Chinese woman presented with a 2-month history of progressive dysphagia for solids, and (less frequently) liquids. She had minimal weight loss and no family history of cancer...
Flexible chitin films as potential wound-dressing materials: wound model studiesNealda Leila Binte Muhammad Yusof
Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543
J Biomed Mater Res A 66:224-32. 2003..Based on histological examination, wound sites dressed with the chitin films stabilized and healed faster, and appeared stronger than those dressed with Opsite trade mark and gauze dressings after 7 days of healing...
Non-invasive models for predicting histology in patients with chronic hepatitis BChun Tao Wai
Department of Medicine, National University Hospital, Singapore
Liver Int 26:666-72. 2006..We aimed to evaluate non-invasive markers for diagnosing significant fibrosis/cirrhosis in patients with CHB, and to evaluate accuracy of models from CHC in CHB patients...
Placental metastases from pancreatic adenocarcinoma in pregnancyLin Lin Su
Department of Obstetrics and Gynecology, National University Hospital, Singapore
Acta Obstet Gynecol Scand 85:626-7. 2006
Impact of new legislation on presumed consent on organ donation on liver transplant in Singapore: a preliminary analysisHow-Cheng Low
Department of Gastroenterology and Hepatology, National University Hospital, Singapore
Transplantation 82:1234-7. 2006..Although the revised legislation helped improve the availability of deceased donor organs moderately, other nonlegislative, supplementary measures are needed to further improve the low organ donation rate...
CCAAT/enhancer binding protein alpha knock-in mice exhibit early liver glycogen storage and reduced susceptibility to hepatocellular carcinomaEe Hong Tan
Department of Physiology, National University of Singapore, Singapore
Cancer Res 65:10330-7. 2005..Our data establish that controlled C/EBPalpha production can inhibit liver tumor growth in vivo...
Diffuse uterine adenomatoid tumor in an immunosuppressed renal transplant recipientChee Leong Cheng
Department of Pathology, National University Hospital, Singapore, Republic of Singapore
Int J Gynecol Pathol 22:198-201. 2003..The relationship between immunosuppression and diffuse adenomatoid tumors is discussed...
Hydroxyapatite-chitin materials as potential tissue engineered bone substitutesZigang Ge
Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore
Biomaterials 25:1049-58. 2004..This study demonstrates the potential of HA-chitin matrixes as a good substrate candidate for tissue engineered bone substitute...
Chitosan-alginate PEC membrane as a wound dressing: Assessment of incisional wound healingLishan Wang
Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543
J Biomed Mater Res 63:610-8. 2002..On the basis of its biocompatibility and wound-healing efficacy, the chitosan-alginate PEC membrane can be considered for wound-dressing applications...
