W Q Sun

Summary

Affiliation: National University of Singapore
Country: Singapore

Publications

  1. ncbi Protein inactivation in amorphous sucrose and trehalose matrices: effects of phase separation and crystallization
    W Q Sun
    School of Biological Sciences, National University of Singapore, Singapore
    Biochim Biophys Acta 1425:235-44. 1998
  2. ncbi Protein stability in the amorphous carbohydrate matrix: relevance to anhydrobiosis
    W Q Sun
    Department of Biological Sciences, National University of Singapore, Singapore
    Biochim Biophys Acta 1425:245-54. 1998
  3. ncbi Stability of dry liposomes in sugar glasses
    W Q Sun
    Department of Botany, National University of Singapore, Singapore
    Biophys J 70:1769-76. 1996
  4. ncbi Effect of sucrose/raffinose mass ratios on the stability of co-lyophilized protein during storage above the Tg
    P Davidson
    Department of Biological Sciences, National University of Singapore, Singapore
    Pharm Res 18:474-9. 2001
  5. ncbi Effect of dextran molecular weight on protein stabilization during freeze-drying and storage
    W Q Sun
    Department of Biological Sciences, National University of Singapore
    Cryo Letters 22:285-92. 2001
  6. ncbi Dielectric relaxation of water and water-plasticized biomolecules in relation to cellular water organization, cytoplasmic viscosity, and desiccation tolerance in recalcitrant seed tissues
    W Q Sun
    Department of Biological Sciences, National University of Singapore, Kent Ridge Crescent, Singapore 119260
    Plant Physiol 124:1203-16. 2000

Collaborators

Detail Information

Publications6

  1. ncbi Protein inactivation in amorphous sucrose and trehalose matrices: effects of phase separation and crystallization
    W Q Sun
    School of Biological Sciences, National University of Singapore, Singapore
    Biochim Biophys Acta 1425:235-44. 1998
    ....
  2. ncbi Protein stability in the amorphous carbohydrate matrix: relevance to anhydrobiosis
    W Q Sun
    Department of Biological Sciences, National University of Singapore, Singapore
    Biochim Biophys Acta 1425:245-54. 1998
    ..These results indicate an important role of the glassy state in protein stabilization. Our data suggest an association between protein stability in intracellular glass and seed survival during storage...
  3. ncbi Stability of dry liposomes in sugar glasses
    W Q Sun
    Department of Botany, National University of Singapore, Singapore
    Biophys J 70:1769-76. 1996
    ..The half-life of solute retention in dry liposomes may be prolonged by storing dry liposomes at temperatures below the Tg and by increasing the Tg of the dry liposome preparation...
  4. ncbi Effect of sucrose/raffinose mass ratios on the stability of co-lyophilized protein during storage above the Tg
    P Davidson
    Department of Biological Sciences, National University of Singapore, Singapore
    Pharm Res 18:474-9. 2001
    ..Our data do not support the prediction from recent thermophysical studies that raffinose should be superior to sucrose and trehalose as a potential excipient or stabilizer...
  5. ncbi Effect of dextran molecular weight on protein stabilization during freeze-drying and storage
    W Q Sun
    Department of Biological Sciences, National University of Singapore
    Cryo Letters 22:285-92. 2001
    ..Dextran with an average molecular weight of 512 kD was again found to provide the best protection. Mechanisms that cause the differences in protein stability among different molecular weight dextrans remain unclear...
  6. ncbi Dielectric relaxation of water and water-plasticized biomolecules in relation to cellular water organization, cytoplasmic viscosity, and desiccation tolerance in recalcitrant seed tissues
    W Q Sun
    Department of Biological Sciences, National University of Singapore, Kent Ridge Crescent, Singapore 119260
    Plant Physiol 124:1203-16. 2000
    ..40 g/g dry weight, which was correlated with the great relaxation slowdown of water-plasticized biomolecules, supporting a role for viscosity in metabolic shutdown during dehydration...