Adeline Seow

Summary

Affiliation: National University of Singapore
Country: Singapore

Publications

  1. ncbi Fumes from meat cooking and lung cancer risk in Chinese women
    A Seow
    Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore
    Cancer Epidemiol Biomarkers Prev 9:1215-21. 2000
  2. ncbi Diabetes mellitus and risk of colorectal cancer in the Singapore Chinese Health Study
    Adeline Seow
    Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore
    J Natl Cancer Inst 98:135-8. 2006
  3. ncbi Joint effect of asthma/atopy and an IL-6 gene polymorphism on lung cancer risk among lifetime non-smoking Chinese women
    Adeline Seow
    Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore
    Carcinogenesis 27:1240-4. 2006
  4. ncbi Effect of glutathione-S-transferase polymorphisms on the cancer preventive potential of isothiocyanates: an epidemiological perspective
    Adeline Seow
    Department of Community, Occupational and Family Medicine, National University of Singapore, 16 Medical Drive, MD3, Singapore 117597, Singapore
    Mutat Res 592:58-67. 2005
  5. ncbi Dietary isothiocyanates, glutathione S-transferase polymorphisms and colorectal cancer risk in the Singapore Chinese Health Study
    Adeline Seow
    Department of Community, Occupational and Family Medicine, Faculty of Medicine, National University of Singapore, Singapore
    Carcinogenesis 23:2055-61. 2002
  6. ncbi Food groups and the risk of colorectal carcinoma in an Asian population
    Adeline Seow
    Department of Community, Occupational, and Family Medicine, National University of Singapore, Singapore
    Cancer 95:2390-6. 2002
  7. ncbi Diet, reproductive factors and lung cancer risk among Chinese women in Singapore: evidence for a protective effect of soy in nonsmokers
    Adeline Seow
    Department of Community, Occupational and Family Medicine, Faculty of Medicine MD3, National University of Singapore, 16 Medical Drive, 117597 Singapore
    Int J Cancer 97:365-71. 2002
  8. doi Female reproductive factors, gene polymorphisms in the estrogen metabolism pathway, and risk of lung cancer in Chinese women
    Wei Yen Lim
    Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore
    Am J Epidemiol 175:492-503. 2012
  9. doi Aspirin and non-aspirin non-steroidal anti-inflammatory drug use and risk of lung cancer
    Wei Yen Lim
    Saw Swee Hock School of Public Health, National University of Singapore, MD3, 16 Medical Drive, Singapore 117597, Singapore wei yen
    Lung Cancer 77:246-51. 2012
  10. ncbi Angiotensin I-converting enzyme (ACE) gene polymorphism and breast cancer risk among Chinese women in Singapore
    Woon Puay Koh
    Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore 117597
    Cancer Res 63:573-8. 2003

Detail Information

Publications32

  1. ncbi Fumes from meat cooking and lung cancer risk in Chinese women
    A Seow
    Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore
    Cancer Epidemiol Biomarkers Prev 9:1215-21. 2000
    ..Further studies in different settings are warranted to examine this possibility, which may also help to explain the higher risk observed among women smokers compared with men...
  2. ncbi Diabetes mellitus and risk of colorectal cancer in the Singapore Chinese Health Study
    Adeline Seow
    Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore
    J Natl Cancer Inst 98:135-8. 2006
    ..Our results support the hypothesis that hyperinsulinemia may play a role in colorectal carcinogenesis, even in a relatively lean population...
  3. ncbi Joint effect of asthma/atopy and an IL-6 gene polymorphism on lung cancer risk among lifetime non-smoking Chinese women
    Adeline Seow
    Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore
    Carcinogenesis 27:1240-4. 2006
    ..05). Our findings are consistent with the role of chronic inflammation as an aetiologic factor among non-smoking Asian women, and suggest that asthma/atopy is a risk marker for susceptibility to the development of lung cancer...
  4. ncbi Effect of glutathione-S-transferase polymorphisms on the cancer preventive potential of isothiocyanates: an epidemiological perspective
    Adeline Seow
    Department of Community, Occupational and Family Medicine, National University of Singapore, 16 Medical Drive, MD3, Singapore 117597, Singapore
    Mutat Res 592:58-67. 2005
    ....
  5. ncbi Dietary isothiocyanates, glutathione S-transferase polymorphisms and colorectal cancer risk in the Singapore Chinese Health Study
    Adeline Seow
    Department of Community, Occupational and Family Medicine, Faculty of Medicine, National University of Singapore, Singapore
    Carcinogenesis 23:2055-61. 2002
    ..Further, this gene-diet interaction may be important in studies evaluating the effect of risk-enhancing compounds in the colorectum...
  6. ncbi Food groups and the risk of colorectal carcinoma in an Asian population
    Adeline Seow
    Department of Community, Occupational, and Family Medicine, National University of Singapore, Singapore
    Cancer 95:2390-6. 2002
    ..It has long been known that dietary factors play a role in the risk of this disease, although studies in Asian populations, with their unique dietary intake, have been few...
  7. ncbi Diet, reproductive factors and lung cancer risk among Chinese women in Singapore: evidence for a protective effect of soy in nonsmokers
    Adeline Seow
    Department of Community, Occupational and Family Medicine, Faculty of Medicine MD3, National University of Singapore, 16 Medical Drive, 117597 Singapore
    Int J Cancer 97:365-71. 2002
    ..These findings are consistent with other evidence suggesting an involvement of estrogen-related pathways in lung cancer among non-smoking women...
  8. doi Female reproductive factors, gene polymorphisms in the estrogen metabolism pathway, and risk of lung cancer in Chinese women
    Wei Yen Lim
    Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore
    Am J Epidemiol 175:492-503. 2012
    ..G/G, OR = 1.46, 95% CI: 1.12, 1.90) but not in ever smokers. No associations were seen with other polymorphisms. These results support a risk-enhancing role of estrogens in lung carcinogenesis among never smokers...
  9. doi Aspirin and non-aspirin non-steroidal anti-inflammatory drug use and risk of lung cancer
    Wei Yen Lim
    Saw Swee Hock School of Public Health, National University of Singapore, MD3, 16 Medical Drive, Singapore 117597, Singapore wei yen
    Lung Cancer 77:246-51. 2012
    ..Our results suggest that aspirin consumption may reduce lung cancer risk in Asian women and are consistent with current understanding of the role of cyclooxygenase in lung carcinogenesis...
  10. ncbi Angiotensin I-converting enzyme (ACE) gene polymorphism and breast cancer risk among Chinese women in Singapore
    Woon Puay Koh
    Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore 117597
    Cancer Res 63:573-8. 2003
    ..27-0.81). Our findings support experimental data implicating ACE and angiotensin II in breast cancer, and suggest that the renin-angiotensin system may serve as a therapeutic target for breast cancer treatment and prevention...
  11. ncbi CYP1A1 polymorphisms and risk of lung cancer in non-smoking Chinese women: influence of environmental tobacco smoke exposure and GSTM1/T1 genetic variation
    Daniel P K Ng
    Department of Community, Occupational and Family Medicine, National University of Singapore, 16 Medical Drive MD3, Singapore 117597
    Cancer Causes Control 16:399-405. 2005
    ..We examined whether polymorphisms of CYP1A1, which plays a role in the metabolic activation of polycyclic aromatic hydrocarbons (PAHs), confer an increased risk of lung cancer in lifetime non-smoking Chinese women...
  12. pmc Reproductive variables, soy intake, and lung cancer risk among nonsmoking women in the Singapore Chinese Health Study
    Adeline Seow
    Department of Community, Occupational, and Family Medicine, Yong Loo Lin School of Medicine, 16 Medical Drive, MD3, National University of Singapore 117597, Singapore
    Cancer Epidemiol Biomarkers Prev 18:821-7. 2009
    ..021). These findings add support for the role of hormonal factors in the etiology of lung cancer among nonsmoking women, and are consistent with emerging experimental evidence in this regard...
  13. doi Polymorphisms in inflammatory pathway genes, host factors and lung cancer risk in Chinese female never-smokers
    Wei Yen Lim
    Department of Epidemiology and Public Health National University of Singapore, and Department of Pathology, Tan Tock Seng Hospital, Singapore, Singapore
    Carcinogenesis 32:522-9. 2011
    ..47). Our results suggest that the effect of inflammatory medical conditions on lung cancer in never-smokers is modulated by host genetic susceptibility and will need to be confirmed in other studies conducted in similar populations...
  14. ncbi Dietary exposure to heterocyclic amines in a Chinese population
    Kin Yoke Wong
    Department of Community, Occupational and Family Medicine, Faculty of Medicine, National University of Singapore, Singapore
    Nutr Cancer 52:147-55. 2005
    ..Seven specific meat-cooking method combinations contributed 90.1% of this intake, namely, pan-fried fish, pork, and chicken, deep-fried chicken as well as fish, roasted/barbecued pork, and grilled minced beef...
  15. pmc Chronic rhinosinusitis and risk of lung cancer in the Singapore Chinese Health Study
    Woon Puay Koh
    Department of Community, Occupational and Family Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Int J Cancer 123:1398-402. 2008
    ..11; 95% CI = 0.90-1.36). Chronic rhinosinusitis may be a marker of pan-airway inflammation and its association with lung cancer risk provides evidence linking inflammation to lung carcinogenesis, especially among women...
  16. ncbi Do younger female breast cancer patients have a poorer prognosis? Results from a population-based survival analysis
    Kee Seng Chia
    Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore
    Int J Cancer 108:761-5. 2004
    ..In patients with distant metastases, those younger than 35 years of age had the lowest excess risk of death. At the population level, younger women (< 45 years) with breast cancer in Singapore have higher relative survival rates...
  17. doi Biomass fuels and lung cancer
    Wei Yen Lim
    Saw Swee Hock School of Public Health, National University of Singapore, Singapore
    Respirology 17:20-31. 2012
    ....
  18. ncbi Opposing trends in incidence of esophageal squamous cell carcinoma and adenocarcinoma in a multi-ethnic Asian country
    Mark L Fernandes
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Am J Gastroenterol 101:1430-6. 2006
    ..To describe the incidence trends in esophageal squamous cell carcinoma (SCC) and adenocarcinoma among the three major ethnic groups in Singapore from 1968 to 2002...
  19. pmc Lung cancer in Chinese women: evidence for an interaction between tobacco smoking and exposure to inhalants in the indoor environment
    Li Tang
    Department of Epidemiology and Public Health, National University of Singapore, Singapore
    Environ Health Perspect 118:1257-60. 2010
    ....
  20. ncbi Improving adherence to regular pap smear screening among Asian women: a population-based study in Singapore
    Jeannette Lee
    Department of Community, Occupational and Family Medicine, Faculty of Medicine, National University of Singapore
    Health Educ Behav 29:207-18. 2002
    ..One third of women who have ever had a smear do not return for regular screening. Appropriate windows of opportunity in contact between women and the health care services should be used to convey the importance of adherence to screening...
  21. ncbi Population-based survival analysis of colorectal cancer patients in Singapore, 1968-1992
    Wen Bo Du
    Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore
    Int J Cancer 99:460-5. 2002
    ..Our study shows a unique changing pattern of survival experience for colorectal patients from a country undergoing rapid economic development...
  22. doi Sun exposure and risk of lymphoid neoplasms in Singapore
    Kin Yoke Wong
    Saw Swee Hock School of Public Health, National University of Singapore, Singapore
    Cancer Causes Control 23:1055-64. 2012
    ..We evaluated the association between personal outdoor sun exposure and risk of malignant lymphomas in Singapore...
  23. ncbi Graduate public health education--Singapore's contribution to strengthening capacity in the region and beyond
    Meng Kin Lim
    Department of Community, Occupational and Family Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 16 Medical Drive, Singapore
    Ann Acad Med Singapore 37:1046-50. 2008
    ..It also discusses the role Singapore can continue to play in addressing global inequities in access to public health education and in strengthening public health capacity in the region and beyond...
  24. doi CYP1A1, GSTM1, and GSTT1 polymorphisms, smoking, and lung cancer risk in a pooled analysis among Asian populations
    Kyoung Mu Lee
    Department of Preventive Medicine, Seoul National University College of Medicine, 28 Yongon Dong, Chongno Gu, Seoul 110 799, Korea
    Cancer Epidemiol Biomarkers Prev 17:1120-6. 2008
    ..However, further investigation is warranted considering the relatively small sample size when subgroup analyses were done and the lack of environmental exposure data other than smoking...
  25. ncbi Mammographic parenchymal patterns and self-reported soy intake in Singapore Chinese women
    Rupert W Jakes
    National Medical Research Council Clinical Trials and Epidemiology Research Unit, Singapore 169039
    Cancer Epidemiol Biomarkers Prev 11:608-13. 2002
    ..20-0.98). The association between high soy intake and a reduced risk of mammographic parenchymal patterns that are associated with high breast cancer risk may have important implications in breast cancer prevention...
  26. ncbi HSD17B1 and CYP17 polymorphisms and breast cancer risk among Chinese women in Singapore
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA
    Int J Cancer 104:450-7. 2003
    ..41, 95% CI=1.56-3.72; RR=4.39, 95% CI=1.71-11.30, respectively). The latter gene-parity effects were especially pronounced in postmenopausal women...
  27. ncbi Vitamin D receptor start codon polymorphism and colorectal cancer risk: effect modification by dietary calcium and fat in Singapore Chinese
    Hui Lee Wong
    USC Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA
    Carcinogenesis 24:1091-5. 2003
    ..5-fold increased risk that was statistically significant. There was little evidence of a VDR genotype-colorectal cancer association among subjects with higher than median values of either dietary fat or calcium...
  28. ncbi Determinants of circulating insulin-like growth factor I and insulin-like growth factor binding protein 3 concentrations in a cohort of Singapore men and women
    Nicole M Probst-Hensch
    University Hospital Zurich, Cancer Registry Z├╝rich, Zurich, Switzerland
    Cancer Epidemiol Biomarkers Prev 12:739-46. 2003
    ..The results of this study lend additional support to the hypothesis that circulating IGF-I concentrations increase the risk of prostate, bladder, colorectal, and breast cancer...
  29. ncbi Lack of association between chronic Chlamydophila pneumoniae infection and lung cancer among nonsmoking Chinese women in Singapore
    Woon Puay Koh
    Int J Cancer 114:502-4. 2005
  30. doi Changing patterns of Hodgkin lymphoma incidence in Singapore
    Henrik Hjalgrim
    Department of Epidemiology Research, Statens Serum Institut, Denmark
    Int J Cancer 123:716-9. 2008
    ....
  31. ncbi Soy intake and other lifestyle determinants of serum estrogen levels among postmenopausal Chinese women in Singapore
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90089, USA
    Cancer Epidemiol Biomarkers Prev 11:844-51. 2002
    ..Current smokers showed significantly higher E(2) levels (28%) than nonsmokers (P = 0.04). These findings are discussed in relation to the recent doubling of breast cancer incidence among Chinese women in Singapore...
  32. ncbi Population-based survival for cervical cancer in Singapore, 1968-1992
    Hao Wang
    Singapore Cancer Registry, Department of Pathology, Singapore
    Am J Obstet Gynecol 188:324-9. 2003
    ..The aim of this study was to describe the cervical cancer survival rates in Singapore during the period of 1968 through 1992 using population-based data...