Research Topics
| Kang NingSummaryAffiliation: National University of Singapore Country: Singapore Publications
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Detail Information
Publications
Algorithm for peptide sequencing by tandem mass spectrometry based on better preprocessing and anti-symmetric computational modelKang Ning
Department of Computer Science, National University of Singapore, Block S15, 3 Science Drive 2, Singapore 117543, Singapore
Comput Syst Bioinformatics Conf 6:19-30. 2007..We have also proposed a novel algorithm which incorporate preprocessing and new model for anti-symmetric issue, and experiments show that this algorithm has better performance on datasets examined...
Towards a better solution to the shortest common supersequence problem: the deposition and reduction algorithmKang Ning
Department of Computer Science, National University of Singapore, Science Drive, Singapore 117543, Singapore
BMC Bioinformatics 7:S12. 2006..Unfortunately, most do not work well on large SCS instances where there are many, long sequences...
On preprocessing and antisymmetry in de novo peptide sequencing: improving efficiency and accuracyKang Ning
Department of Computer Science, National University of Singapore, Block S15, 3 Science Drive 2, Singapore 117543, Singapore
J Bioinform Comput Biol 6:467-92. 2008..We integrate our findings on preprocessing and the antisymmetry problem with some current models for peptide sequencing. Experimental results show that our findings help to improve accuracies for de novo sequencing...
The distribution and deposition algorithm for multiple oligo nucleotide arraysKang Ning
Department of Computer Science, National University of Singapore, 3 Science Drive 2 117543, Singapore
Genome Inform 17:89-99. 2006..Two other algorithms were also proposed and used for comparison. Experiments show that our algorithm can effectively output short synthesis sequences for multiple arrays, and the algorithm is efficient...
PepSOM: an algorithm for peptide identification by tandem mass spectrometry based on SOMKang Ning
Department of Computer Science, School of Computing, National University of Singapore, 3 Science Drive 2, 117543, Singapore
Genome Inform 17:194-205. 2006..Experiments show that our algorithm is both fast and accurate in peptide identification...
An accurate and efficient algorithm for Peptide and ptm identification by tandem mass spectrometryKang Ning
Department of Computer Science, School of Computing, National University of Singapore, Computing 1, Singapore 117590
Genome Inform 19:119-30. 2007..Experiments showed that our algorithm is both fast and accurate for peptide identification. Experiments on spectra with simulated and real PTMs confirmed that our algorithm is accurate for identifying PTMs...
Using indirect protein-protein interactions for protein complex predictionHon Nian Chua
Graduate School of Integrated Sciences, National University of Singapore, Singapore
J Bioinform Comput Biol 6:435-66. 2008..Since no other information except the original PPI network is used, our approach would be very useful for protein complex prediction, especially for prediction of novel protein complexes...
MCL-CAw: a refinement of MCL for detecting yeast complexes from weighted PPI networks by incorporating core-attachment structureSriganesh Srihari
Department of Computer Science, National University of Singapore, Singapore
BMC Bioinformatics 11:504. 2010..However, MCL produces many noisy clusters, which either do not match known complexes or have additional proteins that reduce the accuracies of correctly predicted complexes...
Modeling and characterization of multi-charge mass spectra for peptide sequencingKet Fah Chong
Department of Computer Science, National University of Singapore, 3 Science Drive 2, Singapore 117543, Singapore
J Bioinform Comput Biol 4:1329-52. 2006..Evaluation on multi-charge spectra shows that our simple GBST algorithm outperforms Lutefisk and PepNovo, especially for the GPM spectra of charge three or more...
Using indirect protein-protein interactions for protein complex predicationHon Nian Chua
Graduate School of Integrated Sciences, National University of Singapore, Singapore
Comput Syst Bioinformatics Conf 6:97-109. 2007..Since no any other information except the original PPI network is used, our approach would be very useful for protein complex prediction, especially for prediction of novel protein complexes...
Refining Markov Clustering for protein complex prediction by incorporating core-attachment structureSriganesh Srihari
School of Computing, National University of Singapore, Singapore 117590, Singapore
Genome Inform 23:159-68. 2009..We also discuss several instances to show that our predicted complexes clearly adhere to the core-attachment structure as revealed by Gavin et al...
A post-processing method for optimizing synthesis strategy for oligonucleotide microarraysKang Ning
Department of Computer Science, National University of Singapore Singapore 117543
Nucleic Acids Res 33:e144. 2005....
The antibody preparation and expression of human PescadilloHao Zhang
Beijing Institute of Biotechnology, Beijing, 100850, China
Sci China C Life Sci 50:298-304. 2007..Taken together, these data suggest that Pescadillo may play important roles in the initiation and development of cancer and may be a potential target in cancer diagnosis and therapy...
