Anselm Mak

Summary

Affiliation: National University of Singapore
Country: Singapore

Publications

  1. doi request reprint Global trends, potential mechanisms and early detection of organ damage in SLE
    Anselm Mak
    Division of Rheumatology, Department of Medicine, University Medicine Cluster, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Level 10, NUHS Tower Block, Singapore 119228
    Nat Rev Rheumatol 9:301-10. 2013
  2. doi request reprint Serum tumour necrosis factor-alpha is associated with poor health-related quality of life and depressive symptoms in patients with systemic lupus erythematosus
    A Mak
    Division of Rheumatology, Department of Medicine, University Medicine Cluster, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Lupus 22:254-61. 2013
  3. doi request reprint Significantly higher estimated 10-year probability of fracture in lupus patients with bone mineral density comparable to that of healthy individuals
    Anselm Mak
    Division of Rheumatology, Department of Medicine, National University Hospital, University Medicine Cluster, Yong Loo Lin School of Medicine, National University of Singapore, Level 10, NUHS Tower Block, 1E Kent Ridge Road, Singapore 119228, Singapore
    Rheumatol Int 33:299-307. 2013
  4. doi request reprint Global trend of survival and damage of systemic lupus erythematosus: meta-analysis and meta-regression of observational studies from the 1950s to 2000s
    Anselm Mak
    Division of Rheumatology, Department of Medicine, University Medicine Cluster, National University of Singapore, Singapore
    Semin Arthritis Rheum 41:830-9. 2012
  5. doi request reprint A prospective functional MRI study for executive function in patients with systemic lupus erythematosus without neuropsychiatric symptoms
    Anselm Mak
    Division of Rheumatology, Department of Medicine, University Medicine Cluster, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Semin Arthritis Rheum 41:849-58. 2012
  6. doi request reprint The economic burden of systemic lupus erythematosus in Asia: the current state
    A Mak
    Division of Rheumatology, Department of Medicine, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Lupus 19:1442-6. 2010
  7. doi request reprint Meta-analysis in medicine: an introduction
    Anselm Mak
    Division of Rheumatology, Department of Medicine, University Medical Cluster, Yong Loo Lin School of Medicine, National University of Singapore, Singapore City, Singapore
    Int J Rheum Dis 13:101-4. 2010
  8. doi request reprint Combination of heparin and aspirin is superior to aspirin alone in enhancing live births in patients with recurrent pregnancy loss and positive anti-phospholipid antibodies: a meta-analysis of randomized controlled trials and meta-regression
    Anselm Mak
    Department of Medicine, Division of Rheumatology, University Medical Cluster, National University Health System, Yong Loo Lin School of Medicine, Singapore
    Rheumatology (Oxford) 49:281-8. 2010
  9. pmc Bisphosphonates and atrial fibrillation: Bayesian meta-analyses of randomized controlled trials and observational studies
    Anselm Mak
    Division of Rheumatology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    BMC Musculoskelet Disord 10:113. 2009
  10. doi request reprint Mycophenolate mofetil is as efficacious as, but safer than, cyclophosphamide in the treatment of proliferative lupus nephritis: a meta-analysis and meta-regression
    Anselm Mak
    Division of Rheumatology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Rheumatology (Oxford) 48:944-52. 2009

Detail Information

Publications34

  1. doi request reprint Global trends, potential mechanisms and early detection of organ damage in SLE
    Anselm Mak
    Division of Rheumatology, Department of Medicine, University Medicine Cluster, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Level 10, NUHS Tower Block, Singapore 119228
    Nat Rev Rheumatol 9:301-10. 2013
    ....
  2. doi request reprint Serum tumour necrosis factor-alpha is associated with poor health-related quality of life and depressive symptoms in patients with systemic lupus erythematosus
    A Mak
    Division of Rheumatology, Department of Medicine, University Medicine Cluster, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Lupus 22:254-61. 2013
    ..We aim to explore potential relationships between lupus-related proinflammatory cytokines, HRQoL and depressive symptoms in patients with SLE...
  3. doi request reprint Significantly higher estimated 10-year probability of fracture in lupus patients with bone mineral density comparable to that of healthy individuals
    Anselm Mak
    Division of Rheumatology, Department of Medicine, National University Hospital, University Medicine Cluster, Yong Loo Lin School of Medicine, National University of Singapore, Level 10, NUHS Tower Block, 1E Kent Ridge Road, Singapore 119228, Singapore
    Rheumatol Int 33:299-307. 2013
    ..Advanced age, lower hip BMD, cumulative glucocorticoid and higher anti-dsDNA level independently predicted higher 10-year fracture risk amongst SLE patients...
  4. doi request reprint Global trend of survival and damage of systemic lupus erythematosus: meta-analysis and meta-regression of observational studies from the 1950s to 2000s
    Anselm Mak
    Division of Rheumatology, Department of Medicine, University Medicine Cluster, National University of Singapore, Singapore
    Semin Arthritis Rheum 41:830-9. 2012
    ..To assess systemically with meta-analysis the trend of survival and its determinants, which are hindering further improvement of survival of patients with systemic lupus erythematosus (SLE) over the past 5 decades...
  5. doi request reprint A prospective functional MRI study for executive function in patients with systemic lupus erythematosus without neuropsychiatric symptoms
    Anselm Mak
    Division of Rheumatology, Department of Medicine, University Medicine Cluster, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Semin Arthritis Rheum 41:849-58. 2012
    ..To study the functional brain activation signals before and after sufficient disease control in patients with systemic lupus erythematosus (SLE) without clinical neuropsychiatric symptoms...
  6. doi request reprint The economic burden of systemic lupus erythematosus in Asia: the current state
    A Mak
    Division of Rheumatology, Department of Medicine, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Lupus 19:1442-6. 2010
    ..In this paper, we review the current state of cost-of-illness research on lupus in Asia and analyze the reasons why such studies are urgently required in the Asia Pacific region...
  7. doi request reprint Meta-analysis in medicine: an introduction
    Anselm Mak
    Division of Rheumatology, Department of Medicine, University Medical Cluster, Yong Loo Lin School of Medicine, National University of Singapore, Singapore City, Singapore
    Int J Rheum Dis 13:101-4. 2010
    ..Important terminology related to meta-analysis, the systematic ways to critically appraise, and finally the preferred methodology of conducting meta-analysis will be covered in the subsequent three reviews of this mini-series...
  8. doi request reprint Combination of heparin and aspirin is superior to aspirin alone in enhancing live births in patients with recurrent pregnancy loss and positive anti-phospholipid antibodies: a meta-analysis of randomized controlled trials and meta-regression
    Anselm Mak
    Department of Medicine, Division of Rheumatology, University Medical Cluster, National University Health System, Yong Loo Lin School of Medicine, Singapore
    Rheumatology (Oxford) 49:281-8. 2010
    ..We performed a meta-analysis of randomized controlled trials (RCTs) to assess whether this combination works better than aspirin alone...
  9. pmc Bisphosphonates and atrial fibrillation: Bayesian meta-analyses of randomized controlled trials and observational studies
    Anselm Mak
    Division of Rheumatology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    BMC Musculoskelet Disord 10:113. 2009
    ..We performed a Bayesian meta-analysis to address the possible association between the occurrence of AF and bisphosphonate use and estimated the posterior probability of development of AF with bisphosphonate use...
  10. doi request reprint Mycophenolate mofetil is as efficacious as, but safer than, cyclophosphamide in the treatment of proliferative lupus nephritis: a meta-analysis and meta-regression
    Anselm Mak
    Division of Rheumatology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Rheumatology (Oxford) 48:944-52. 2009
    ..An updated meta-analysis is therefore required...
  11. ncbi request reprint Lumbar spine bone mineral density predicts endothelial reactivity in patients with systemic lupus erythematosus
    A Mak
    National University of Singapore
    Clin Exp Rheumatol 29:261-8. 2011
    ..To explore whether endothelial function is related to bone mineral density (BMD) in patients with systemic lupus erythematosus (SLE)...
  12. doi request reprint Atherogenic serum lipid profile is an independent predictor for gouty flares in patients with gouty arthropathy
    A Mak
    Department of Medicine, Division of Rheumatology, National University Hospital, National University of Singapore, 5 Lower Kent Ridge Road, Singapore 119074
    Rheumatology (Oxford) 48:262-5. 2009
    ..While prevalent in patients with gout, whether atherogenic lipid profile is associated with gouty flares is unknown. This study aims to investigate whether atherogenic serum lipid predicts gouty flares in patients with gout...
  13. ncbi request reprint Neuropsychiatric lupus and reversible posterior leucoencephalopathy syndrome: a challenging clinical dilemma
    A Mak
    Division of Rheumatology, Department of Medicine, National University Hospital, National University of Singapore, 5 Lower Kent Ridge Road, Singapore 119074
    Rheumatology (Oxford) 47:256-62. 2008
    ..Such treatment strategy ensures a very high chance of total neurological recovery in lupus patients with RPLS...
  14. doi request reprint Damage accrual, cumulative glucocorticoid dose and depression predict anxiety in patients with systemic lupus erythematosus
    Anselm Mak
    Division of Rheumatology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
    Clin Rheumatol 30:795-803. 2011
    ..Logistic regression model showed that higher damage accrual, higher cumulative glucocorticoid dose, depression and fewer regular medications predicted anxiety in SLE patients, with an accuracy of 90% by the ROC analysis...
  15. doi request reprint Clinical and psychosocial factors associated with depression and anxiety in Singaporean patients with rheumatoid arthritis
    Roger C M Ho
    Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Int J Rheum Dis 14:37-47. 2011
    ..To assess the frequency of, and factors associated with, depression and anxiety in Singaporean patients with rheumatoid arthritis (RA)...
  16. doi request reprint How to critically appraise and apply meta-analyses in clinical practice
    Roger C M Ho
    Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Int J Rheum Dis 13:294-9. 2010
    ..Prompted by a clinical question, we critically appraised a meta-analysis of efficacy and safety of mycophenolate mofetil (MMF) versus cyclophosphamide (CYC) in the treatment of proliferative lupus nephritis...
  17. doi request reprint Prevalence of anxiety and depressive symptoms in adolescents with asthma: a meta-analysis and meta-regression
    Yanxia Lu
    Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Pediatr Allergy Immunol 23:707-15. 2012
    ....
  18. doi request reprint The role of interleukin (IL)-17 in anxiety and depression of patients with rheumatoid arthritis
    Yang Liu
    Department of Psychological Medicine, University Medicine Cluster, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Int J Rheum Dis 15:183-7. 2012
    ..We used rheumatoid arthritis (RA) as an inflammatory disease model to explore such relationships...
  19. doi request reprint Is high homocysteine level a risk factor for cognitive decline in elderly? A systematic review, meta-analysis, and meta-regression
    Roger C M Ho
    Department of Psychological Medicine, Yong Loo Lin School of Medicine, Singapore
    Am J Geriatr Psychiatry 19:607-17. 2011
    ..It remains unclear whether the findings can be generalized across studies...
  20. doi request reprint Prevalence of depressive symptoms in patients with chronic obstructive pulmonary disease: a systematic review, meta-analysis and meta-regression
    Melvyn W B Zhang
    Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Gen Hosp Psychiatry 33:217-23. 2011
    ....
  21. doi request reprint Interleukin (IL)-6, tumour necrosis factor alpha (TNF-α) and soluble interleukin-2 receptors (sIL-2R) are elevated in patients with major depressive disorder: a meta-analysis and meta-regression
    Yang Liu
    Department of Psychological Medicine, University Medicine Cluster, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Affect Disord 139:230-9. 2012
    ....
  22. doi request reprint Conducting a meta-analysis: basics and good practices
    Mike W L Cheung
    Department of Psychology, Faculty of Arts and Social Sciences, National University of Singapore, Singapore
    Int J Rheum Dis 15:129-35. 2012
    ..Next, a real data set from a published meta-analysis will be used to illustrate the procedures and interpretations. Last, software packages that may be used to conduct meta-analyses will be highlighted...
  23. doi request reprint Cutaneous complications among i.v. buprenorphine users
    Roger C M Ho
    Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Dermatol 36:22-9. 2009
    ..A high index of suspicion coupled with a correct choice of antibiotics based on local bacteriological surveillance is necessary in an attempt to reduce cutaneous complications and length of hospitalization...
  24. doi request reprint Pulmonary hypertension in first episode infective endocarditis among intravenous buprenorphine users: case report
    Roger C M Ho
    Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Am J Drug Alcohol Abuse 35:199-202. 2009
    ....
  25. doi request reprint The effect of severity of depressive disorder on economic burden in a university hospital in Singapore
    Roger C M Ho
    Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 5 Lower Kent Ridge Road, 119074, Singapore
    Expert Rev Pharmacoecon Outcomes Res 13:549-59. 2013
    ..Depressive disorder is treatable but costly, thus influencing quality of life of people. Aim: Determine direct and indirect costs incurred by depressive disorder in Singapore...
  26. doi request reprint The influence of childhood atopic dermatitis on health of mothers, and its impact on Asian families
    Roger C M Ho
    Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Pediatr Allergy Immunol 21:501-7. 2010
    ..Further research will be welcomed as the results of this study mainly applied to Asian society which could be different to populations from other geographic areas...
  27. doi request reprint Endothelium-dependent but not endothelium-independent flow-mediated dilation is significantly reduced in patients with systemic lupus erythematosus without vascular events: a metaanalysis and metaregression
    Anselm Mak
    Division of Rheumatology, Department of Medicine, University Medicine Cluster, National University Health System, National University of Singapore, Singapore
    J Rheumatol 38:1296-303. 2011
    ....
  28. doi request reprint Polymorphisms of the serotonin transporter gene and post-stroke depression: a meta-analysis
    Kwok Kei Mak
    Department of Community Medicine and School of Public Health, University of Hong Kong, Hong Kong
    J Neurol Neurosurg Psychiatry 84:322-8. 2013
    ....
  29. doi request reprint Intracellular tubulo-reticular structures of peripheral blood mononuclear cells as an ultra-structural marker of disease activity in systemic lupus erythematosus: a pilot study
    Anselm Mak
    Division of Rheumatology, Department of Medicine, University Medicine Cluster, Singapore City, Singapore
    Int J Rheum Dis 16:692-7. 2013
    ..We aim to explore whether TRS formation in the peripheral blood mononuclear cells (PBMCs) of patients with systemic lupus erythematosus (SLE) correlates with more active disease where physiological stress prevails...
  30. ncbi request reprint Research on psychoneuroimmunology: does stress influence immunity and cause coronary artery disease?
    Roger C M Ho
    Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Ann Acad Med Singapore 39:191-6. 2010
    ..This paper also highlights potential research areas and implications of early detection of immunological changes and cardiovascular risk in people under high psychological stress...
  31. ncbi request reprint Renal damage in systemic lupus erythematosus: a comparative analysis of different age groups
    A Mak
    Department of Medicine and Geriatrics, Tuen Mun Hospital, Tsing Chung Koon Road, Hong Kong SAR
    Lupus 16:28-34. 2007
    ..Late onset SLE patients had accrued more renal damage but age did not correlate with renal damage after adjustment for various clinical parameters...
  32. pmc Mycophenolate mofetil for lupus related myelopathy
    C C Mok
    Ann Rheum Dis 65:971-3. 2006
  33. ncbi request reprint Mycophenolate mofetil for refractory haemolytic anemia in systemic lupus erythematosus
    A Mak
    Department of Medicine, Tuen Mun Hospital, New Territories, Hong Kong SAR, China
    Lupus 14:856-8. 2005
    ..The mechanisms of action of MMF are briefly reviewed...
  34. ncbi request reprint Bone mineral density in postmenopausal Chinese patients with systemic lupus erythematosus
    C C Mok
    Department of Medicine, Tuen Mun Hospital, New Territories, Hong Kong, SAR, China
    Lupus 14:106-12. 2005
    ..Active intervention should be considered. The protective role of HCQ has to be confirmed with further studies...