Erle C H Lim

Summary

Affiliation: National University of Singapore
Country: Singapore

Publications

  1. ncbi request reprint Take a bao if you are not superstitious
    Erle C H Lim
    Yong Loo Lin School of Medicine, National University of Singapore
    Ann Acad Med Singapore 36:217-20. 2007
  2. ncbi request reprint Topical botulinum toxin to treat hyperhidrosis? No sweat!
    Erle C H Lim
    Division of Neurology, Yong Loo Lin School of Medicine, National University of Singapore National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
    Med Hypotheses 67:27-32. 2006
  3. doi request reprint In-house medical education: redefining tele-education
    Erle C H Lim
    Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Teach Learn Med 20:193-5. 2008
  4. ncbi request reprint Can botulinum toxin put the restless legs syndrome to rest?
    Erle C H Lim
    Yong Loo Lin School of Medicine, National University of Singapore, Singapore, National University Hospital, Singapore
    Med Hypotheses 69:497-501. 2007
  5. doi request reprint Overcoming preconceptions and perceived barriers to medical communication using a 'dual role-play' training course
    E C H Lim
    Yong Loo Lin School of Medicine and Department of Medicine, Division of Neurology, National University Hospital, Singapore
    Intern Med J 38:708-13. 2008
  6. ncbi request reprint Stop! In the name of love! (Before you fail, not pass!)
    Erle C H Lim
    Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Teach Learn Med 19:198-9. 2007
  7. doi request reprint Oxidative damage in Parkinson disease: Measurement using accurate biomarkers
    Raymond C S Seet
    Department of Medicine, National University of Singapore, Singapore
    Free Radic Biol Med 48:560-6. 2010
  8. doi request reprint Oxidative damage in ischemic stroke revealed using multiple biomarkers
    Raymond C S Seet
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Stroke 42:2326-9. 2011
  9. doi request reprint Oral zinc supplementation does not improve oxidative stress or vascular function in patients with type 2 diabetes with normal zinc levels
    Raymond C S Seet
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Atherosclerosis 219:231-9. 2011
  10. pmc Markers of oxidative damage are not elevated in otherwise healthy individuals with the metabolic syndrome
    Raymond C S Seet
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Diabetes Care 33:1140-2. 2010

Collaborators

Detail Information

Publications63

  1. ncbi request reprint Take a bao if you are not superstitious
    Erle C H Lim
    Yong Loo Lin School of Medicine, National University of Singapore
    Ann Acad Med Singapore 36:217-20. 2007
    ..Singaporeans are superstitious, and medical staff are no exception to the rule. We conducted a survey to determine the prevalence of superstitious beliefs and practices amongst doctors, nurses and medical students in Singapore...
  2. ncbi request reprint Topical botulinum toxin to treat hyperhidrosis? No sweat!
    Erle C H Lim
    Division of Neurology, Yong Loo Lin School of Medicine, National University of Singapore National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
    Med Hypotheses 67:27-32. 2006
    ..We examine the rationale and feasibility for such a treatment modality and route of administration...
  3. doi request reprint In-house medical education: redefining tele-education
    Erle C H Lim
    Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Teach Learn Med 20:193-5. 2008
    ....
  4. ncbi request reprint Can botulinum toxin put the restless legs syndrome to rest?
    Erle C H Lim
    Yong Loo Lin School of Medicine, National University of Singapore, Singapore, National University Hospital, Singapore
    Med Hypotheses 69:497-501. 2007
    ..We postulate that BTX can be injected subcutaneously to the lower limbs to effect amelioration of the symptoms of RLS...
  5. doi request reprint Overcoming preconceptions and perceived barriers to medical communication using a 'dual role-play' training course
    E C H Lim
    Yong Loo Lin School of Medicine and Department of Medicine, Division of Neurology, National University Hospital, Singapore
    Intern Med J 38:708-13. 2008
    ..The aim of the study was to assess the usefulness of a DRP communication course for physicians and to identify factors that inhibit effective medical communication...
  6. ncbi request reprint Stop! In the name of love! (Before you fail, not pass!)
    Erle C H Lim
    Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Teach Learn Med 19:198-9. 2007
  7. doi request reprint Oxidative damage in Parkinson disease: Measurement using accurate biomarkers
    Raymond C S Seet
    Department of Medicine, National University of Singapore, Singapore
    Free Radic Biol Med 48:560-6. 2010
    ..305, p= 0.023) and plasma total HETEs (r= -0.285, p= 0.043). Oxidative damage markers are systemically elevated in PD, which may give clues about the relation of oxidative damage to the onset and progression of PD...
  8. doi request reprint Oxidative damage in ischemic stroke revealed using multiple biomarkers
    Raymond C S Seet
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Stroke 42:2326-9. 2011
    ..We investigated changes in oxidative damage after ischemic stroke using multiple biomarkers...
  9. doi request reprint Oral zinc supplementation does not improve oxidative stress or vascular function in patients with type 2 diabetes with normal zinc levels
    Raymond C S Seet
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Atherosclerosis 219:231-9. 2011
    ..We aimed to assess the effects of zinc supplementation using a range of reliable biomarkers of oxidative damage and vascular function in patients with type 2 diabetes...
  10. pmc Markers of oxidative damage are not elevated in otherwise healthy individuals with the metabolic syndrome
    Raymond C S Seet
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Diabetes Care 33:1140-2. 2010
    ..The role of oxidative damage in the pathogenesis of metabolic syndrome is poorly understood...
  11. doi request reprint Biomarkers of oxidative damage in cigarette smokers: which biomarkers might reflect acute versus chronic oxidative stress?
    Raymond C S Seet
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Free Radic Biol Med 50:1787-93. 2011
    ..Thus, different biomarkers do not measure identical aspects of oxidative stress...
  12. doi request reprint Can demographic and admission laboratory variables be useful to identify long-stay patients with acute ischemic stroke? A hospital-based cohort study in Singapore
    Raymond C S Seet
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
    Neurol Sci 30:275-80. 2009
    ..70, sensitivity 68%, specificity 80%, positive-predictive value 39% and negative-predictive value 95%. Application of this information may assist physicians to triage patients at risk of severe stroke for early therapy and care...
  13. ncbi request reprint Computer-based versus pen-and-paper testing: students' perception
    Erle C H Lim
    Department of Medicine, National University of Singapore, Singapore
    Ann Acad Med Singapore 35:599-603. 2006
    ..Since 2004, our medical school has utilised CBT to conduct 2 papers for the third- and final-year assessments - Paper 3, with 30 multiple choice questions featuring clinical vignettes, and the modified essay question (MEQ) paper...
  14. ncbi request reprint Cyclooxygenase-1 mediated platelet reactivity in young male smokers
    Wai Mun Loke
    1Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Clin Appl Thromb Hemost 20:371-7. 2014
    ..The purpose of this study is to investigate the acute and chronic effects of cigarette smoking on cyclooxygenase- 1(COX-1)-mediated platelet reactivity among cigarette smokers...
  15. doi request reprint Acute effects of cigarette smoking on insulin resistance and arterial stiffness in young adults
    Raymond C S Seet
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 1E, NUHS Tower Block, Kent Ridge Road, Singapore 119228, Singapore
    Atherosclerosis 224:195-200. 2012
    ..The purpose of the study was to evaluate the acute effects of cigarette smoking on insulin resistance and arterial stiffness in a cohort of young healthy adults...
  16. doi request reprint Orofacial dystonia triggered by mouth closure
    Chong Han Pek
    National University Health System, National University of Singapore, Singapore
    Clin Neurol Neurosurg 112:79-81. 2010
    ..Injection of BTX produced complete resolution of task-specific dystonia for 4.5 months...
  17. ncbi request reprint Where has all the botox gone? (how) will we ever learn... using monoclonal antibodies to track botulinum toxin
    Erle C H Lim
    Division of Neurology, Yong Loo Lin School of Medicine, National University of Singapore National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
    Med Hypotheses 67:440-6. 2006
    ..e. unaltered) BTX...
  18. ncbi request reprint Does high-dose coenzyme q10 improve oxidative damage and clinical outcomes in Parkinson's disease?
    Raymond Chee Seong Seet
    1 Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
    Antioxid Redox Signal 21:211-7. 2014
    ..These results lead to the hypothesis that the therapeutic response to CoQ10 depends on baseline levels of ubiquinol and whether the dosage of CoQ10 used can ameliorate the burden of oxidative damage. Antioxid. Redox Signal. 21: 211-217. ..
  19. doi request reprint Accurate targeting of botulinum toxin injections: how to and why
    Erle C H Lim
    Division of Neurology, National University Hospital, National University Health System, National University of Singapore, Singapore
    Parkinsonism Relat Disord 17:S34-9. 2011
    ..Finally, electrical-stimulation EMG or U/S (or a combination of both) would be most suitable when injecting the forearm muscles for spasticity or writer's cramps...
  20. ncbi request reprint Harnessing the IT factor in medical education
    Erle C H Lim
    Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Ann Acad Med Singapore 37:1051-4. 2008
    ..We describe several pedagogical initiatives that we have undertaken at our university school of medicine...
  21. doi request reprint Relationship between circulating vascular endothelial growth factor and its soluble receptors in adults with dengue virus infection: a case-control study
    Raymond C S Seet
    Department of Medicine, Yong Loo Lin School of Medicine, National University, and Department of Medicine, National University Hospital, Singapore
    Int J Infect Dis 13:e248-53. 2009
    ..We performed a case-control study to assess the relationship between vascular endothelial growth factor (VEGF) and its soluble receptors (sVEGFR-1 and 2) in adult patients with dengue fever (DF) and dengue hemorrhagic fever (DHF)...
  22. pmc Augmentation of 5-lipoxygenase activity and expression during dengue serotype-2 infection
    Wai Mun Loke
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 1E, NUHS Tower Block, Kent Ridge Road, Singapore
    Virol J 10:322. 2013
    ..In vitro studies were performed to examine the effects of live and heat-inactivated DENV-2 on the activities and expression of 5-lipoxygenase in human neutrophils...
  23. doi request reprint Oxidative damage in dengue fever
    Raymond C S Seet
    Department of Medicine, Yong Loo Lin School of Medicine, National University Hospital, Singapore 119074
    Free Radic Biol Med 47:375-80. 2009
    ..01). Markers of oxidative damage are altered during the various stages of dengue infection...
  24. ncbi request reprint Botulinum toxin: a novel therapeutic option for bronchial asthma?
    Erle C H Lim
    Yong Loo Lin School of Medicine, National University of Singapore, Division of Neurology, National University Hospital, Singapore
    Med Hypotheses 66:915-9. 2006
    ..We explore the possibility that administration of botulinum toxin may achieve the same effect in bronchial asthma and examine the evidence to support this hypothesis...
  25. doi request reprint Novel chloride channel mutations leading to mild myotonia among Chinese
    Jean Marc Burgunder
    Division of Neurology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Neuromuscul Disord 18:633-40. 2008
    ..Our data suggest that myotonia congenita caused by CLCN1 mutations in Chinese have similar variable features to those found in the West...
  26. pmc A woman with progressive ataxia and hemiparesis on the right side: where's the lesion?
    Jing Hui Yik
    Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    CMAJ 177:247-8. 2007
  27. ncbi request reprint A core skills simulation module
    Erle C H Lim
    National University of Singapore, c o Division of Neurology, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
    Med Educ 40:1135-6. 2006
  28. ncbi request reprint Images in neuroscience. Slowly progressive hemiparesis
    Erle C H Lim
    Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Clin Neurosci 14:966-7, 1007-8. 2007
  29. ncbi request reprint Acceptability of medical students by patients from private and public family practices and specialist outpatient clinics
    Gerald C H Koh
    Department of Epidemiology and Public Health, National University of Singapore, Singapore
    Ann Acad Med Singapore 39:555-10. 2010
    ..We studied patient acceptability of medical student teaching in private and public family practices and public hospital specialist outpatient clinics in Singapore, and before and after an actual medical student teaching consultation...
  30. ncbi request reprint Botulinum toxin-A injections for spastic toe clawing
    Erle C H Lim
    Division of Neurology, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
    Parkinsonism Relat Disord 12:43-7. 2006
    ....
  31. ncbi request reprint Post-infectious fatigue syndrome in dengue infection
    Raymond C S Seet
    Department of Medicine, Yong Loo Lin School of Medicine, National University Singapore, Singapore
    J Clin Virol 38:1-6. 2007
    ..We prospectively studied the incidence and factors associated with fatigue in a cohort of patients following dengue infection...
  32. pmc A case of intermittent ataxia associated with migraine headaches
    Raymond C S Seet
    Yong Loo Lin School of Medicine, National University of Singapore, Department of Medicine, National University Hospital, Singapore
    CMAJ 177:565-7. 2007
  33. doi request reprint Use of botulinum toxin in the neurology clinic
    Erle C H Lim
    Division of Neurology, National University Health System, National University of Singapore, 1E, NUHS Tower Block, Kent Ridge Road, Singapore 119228
    Nat Rev Neurol 6:624-36. 2010
    ..Important practical aspects, such as the reconstitution of BoNT, dosing, and methods of administration, are also addressed...
  34. doi request reprint Biomarkers of oxidative damage are elevated among individuals with high cardiovascular risk: refining subject selection strategies for antioxidant trials
    Raymond C S Seet
    Department of Medicine, National University Health System, Kent Ridge Road, Singapore
    Free Radic Res 47:283-90. 2013
    ..Cardiovascular risk scores are useful to identify individuals with high burden of oxidative damage who may benefit from antioxidant therapy...
  35. ncbi request reprint Spindle coma from acute midbrain infarction
    Raymond C S Seet
    Division of Neurology, National University Hospital, Singapore
    Neurology 64:2159-60. 2005
  36. ncbi request reprint Images in cardiovascular medicine. Hypertensive brainstem encephalopathy
    Raymond C S Seet
    Department of Medicine, Yong Loo Lin School of Medicine, National University, Singapore
    Circulation 115:e310-1. 2007
  37. ncbi request reprint Symptoms and risk factors of ocular complications following dengue infection
    Raymond C S Seet
    Department of Medicine, Yong Loo Lin School of Medicine, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
    J Clin Virol 38:101-5. 2007
    ..Dengue infection can result in severe ocular complications. We prospectively studied the range of ocular symptoms in a cohort of patients with dengue infection...
  38. pmc Holiday review. Duty of care to the undiagnosed patient: ethical imperative, or just a load of Hogwarts?
    Erle C H Lim
    National University Hospital, Singapore
    CMAJ 175:1557-9. 2006
    ..As long as the intent is beneficent, healers or even the wizard or muggle on the street may intervene and render aid to the afflicted...
  39. ncbi request reprint Too many cooks spoil the broth
    Erle C H Lim
    Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Acad Med 82:474. 2007
  40. ncbi request reprint The challenges of "continuing medical education" in a pandemic era
    Erle C H Lim
    Department of Medicine, National University Health System, National University of Singapore, Singapore
    Ann Acad Med Singapore 38:724-6. 2009
    ....
  41. ncbi request reprint Generalised myoclonus evolving into epilepsia partialis continua due to a cingulate gyrus lesion: case report and review of the literature
    Erle C H Lim
    Division of Neurology, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
    Parkinsonism Relat Disord 10:447-9. 2004
    ..The lack of clear declarative clinical and EEG features highlights the melding of the fields of epileptology and movement disorders...
  42. ncbi request reprint Symptomatic segmental dystonia from a cavernous angioma in the centrum semiovale
    Raymond C S Seet
    Division of Neurology, National University Hospital, 5 Lower Kent Ridge Road, Singapore, Singapore 119074
    Parkinsonism Relat Disord 11:65-7. 2005
    ..This interesting case illustrates how an uncomplicated cavernous angioma can rarely cause segmental dystonia and highlights the importance of neuroimaging in patients with late-onset movement disorders...
  43. ncbi request reprint Close temporal association of bronchial asthma and ischemic colitis--case report and review of the literature
    Raymond C S Seet
    Department of Medicine, National University Hospital, Singapore 119074, Singapore
    Respir Med 99:250-3. 2005
    ..The complex interaction of smooth muscle tone and autonomic nervous system in the etiopathogenesis of bronchial asthma and ischemic colitis is discussed. Further studies should be undertaken to clarify this association...
  44. ncbi request reprint Graves' disease associated with spasmodic truncal flexion
    Lih Ming Loh
    Department of Endocrinology, Singapore General Hospital, Singapore, Singapore
    Parkinsonism Relat Disord 11:117-9. 2005
    ..MRI of the brain and thoracic spine were unremarkable. Thyrotoxicosis is known to cause chorea and tremors, and has rarely been described in association with myoclonus...
  45. ncbi request reprint Frequency of provocative factors in epileptic patients admitted for seizures: a prospective study in Singapore
    Joo Hui Tan
    Division of Neurology, Department of Medicine, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
    Seizure 14:464-9. 2005
    ..Patient education involving epilepsy nurse educators may play an important role in decreasing seizure occurrence and possibly unnecessary hospital admissions...
  46. ncbi request reprint Interesting in- and outpatient attendances at Hogwarts Infirmary and St Mungo's Hospital for magical maladies
    Erle C H Lim
    Division of Neurology, National University Hospital, Singapore
    Ann Acad Med Singapore 35:127-9. 2006
    ..We also provide a basic glossary of magical ailments, and describe their muggle corollaries. Further studies will hopefully result in the development of immunity against the unforgivable curses...
  47. ncbi request reprint Neurological localisation course for postgraduate candidates
    Erle C H Lim
    Division of Neurology, National University Hospital, Singapore
    Med Educ 40:487-8. 2006
  48. ncbi request reprint Blurred vision and dizziness. Ocular flutter
    Raymond C S Seet
    Division of Neurology, National University Hospital, 5 Lower Kent Ridge Road, 119074 Singapore
    J Clin Neurosci 13:356, 404. 2006
  49. ncbi request reprint Acute transverse myelitis following dengue virus infection
    Raymond C S Seet
    Division of Neurology, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
    J Clin Virol 35:310-2. 2006
    ..Further studies need to be performed to elucidate the mechanisms of spinal neurological damage in dengue...
  50. ncbi request reprint Is there a place for placebo in management of psychogenic movement disorders?
    Erle C H Lim
    Division of Neurology, Department of Medicine, National University Hospital, Singapore
    Ann Acad Med Singapore 36:208-10. 2007
    ..Empathy and a non-judgmental manner are essential in dealing with patients, and a neurobiological explanation of the symptoms may help to foster trust, acceptance, understanding and recovery...
  51. ncbi request reprint Images in neuroscience. The slow and clumsy motor cyclist
    Erle C H Lim
    Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Clin Neurosci 14:757, 810. 2007
  52. ncbi request reprint Headaches amongst pool players
    Raymond C S Seet
    Division of Neurology, National University Hospital, Singapore
    Headache 47:270-4. 2007
    ..Pool-players' headache is a newly described entity. We studied the prevalence and risk factors for the development of headaches amongst pool players...
  53. ncbi request reprint Familiarity breeds comprehension: going with what you know
    Erle C H Lim
    Division of Neurology, National University Hospital of Singapore, Singapore
    Acad Med 81:270. 2006
  54. ncbi request reprint Facial paraesthesia
    Raymond C S Seet
    Division of Neurology, National University Hospital, 5 Lower Kent Ridge Road, 119074, Singapore
    J Clin Neurosci 13:102, 150. 2006
  55. ncbi request reprint Images in neuroscience. Cavernous angioma
    Rahul Rathakrishnan
    Division of Neurology, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
    J Clin Neurosci 14:133,188. 2007
  56. pmc Through the looking glass: persistent mirror movements
    Erle C H Lim
    Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    CMAJ 176:619. 2007
  57. ncbi request reprint Diagnosing carpal tunnel syndrome--clinical criteria and ancillary tests
    Einar P Wilder-Smith
    Neurophysiological Section, National University Hospital, Singapore
    Nat Clin Pract Neurol 2:366-74. 2006
    ..Supplementary tests of small nerve fiber function and measurement of intracarpal pressure might, in the future, improve early recognition of CTS, especially in the absence of well-defined symptoms...
  58. pmc Using videotaped vignettes to teach medical students to perform the neurologic examination
    Erle C H Lim
    J Gen Intern Med 21:101. 2006
  59. ncbi request reprint Another injection-free method to effect analgesia when injecting botulinum toxin for palmar hyperhidrosis: cryoanalgesia
    Erle C H Lim
    Dermatol Online J 13:25. 2007
  60. ncbi request reprint Botulinum toxin, Quo Vadis?
    Erle C H Lim
    Med Hypotheses 69:718-23. 2007
    ..In this editorial, we discuss reports of new therapeutic indications of BTX, and propose new areas for research...
  61. pmc What is the place for placebo in the management of psychogenic disease?
    Erle C H Lim
    J R Soc Med 100:60-1. 2007
  62. ncbi request reprint Intravenous use of buprenorphine tablets associated with rhabdomyolysis and compressive sciatic neuropathy
    Raymond C S Seet
    Ann Emerg Med 47:396-7. 2006
  63. pmc The permissible use of placebo
    Erle C H Lim
    J R Soc Med 100:396. 2007