Chi Hang Lee

Summary

Affiliation: National University of Singapore
Country: Singapore

Publications

  1. ncbi request reprint Relation between door-to-balloon time and microvascular perfusion as evaluated by myocardial blush grade, corrected TIMI frame count, and ST-segment resolution in treatment of acute myocardial infarction
    Chi Hang Lee
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Interv Cardiol 22:437-43. 2009
  2. ncbi request reprint Pulmonary embolism as a cause of unexplained sinus tachycardia after right ventricular myocardial infarction
    JingPing Lin
    Cardiac Department, National University Heart Centre, 1E Kent Ridge Road, National University Health System Tower Block, Level 9, Singapore 119228
    Singapore Med J 54:e199-200. 2013
  3. doi request reprint Immigrant status and disparities in health care delivery in patients with myocardial infarction
    Chi Hang Lee
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Int J Cardiol 166:696-701. 2013
  4. doi request reprint Adiponectin profile in Asian patients undergoing coronary revascularization and its association with plaque vulnerability: IDEAS-ADIPO study
    Chi Hang Lee
    Department of Medicine, National University of Singapore, Singapore
    Obesity (Silver Spring) 20:2451-7. 2012
  5. doi request reprint Intravascular ultrasound guided percutaneous coronary intervention: a practical approach
    Chi Hang Lee
    Cardiac Department, National University Heart Centre, Singapore
    J Interv Cardiol 25:86-94. 2012
  6. doi request reprint Correlation between high density lipoprotein-cholesterol and remodeling index in patients with coronary artery disease: IDEAS (IVUS diagnostic evaluation of atherosclerosis in Singapore)-HDL study
    Chi Hang Lee
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Kent Ridge, Singapore
    Int J Cardiovasc Imaging 28:33-41. 2012
  7. doi request reprint Microvascular obstruction after percutaneous coronary intervention
    Chi Hang Lee
    Cardiac Department, National University Heart Center, National University of Singapore, 5, Lower Kent Ridge Road, Singapore 119074
    Catheter Cardiovasc Interv 75:369-77. 2010
  8. ncbi request reprint Procedure-related myonecrosis after bare and drug-eluting stent implantation
    Chi Hang Lee
    Cardiac Department, National University Heart Center, 5 Lower Kent Ridge Road, Singapore
    Asian Cardiovasc Thorac Ann 18:272-8. 2010
  9. doi request reprint Obstructive sleep apnea in patients admitted for acute myocardial infarction. Prevalence, predictors, and effect on microvascular perfusion
    Chi Hang Lee
    Departments of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Chest 135:1488-95. 2009
  10. ncbi request reprint Long-term safety and efficacy are observed after implantation of Zotarolimus-Eluting stent in real-world clinical practice
    Chi Hang Lee
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    EuroIntervention 4:338-44. 2008

Collaborators

Detail Information

Publications48

  1. ncbi request reprint Relation between door-to-balloon time and microvascular perfusion as evaluated by myocardial blush grade, corrected TIMI frame count, and ST-segment resolution in treatment of acute myocardial infarction
    Chi Hang Lee
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Interv Cardiol 22:437-43. 2009
    ..We sought to compare microvascular perfusion in patients who had undergone primary percutaneous coronary intervention with door-to-balloon time < or =90 minute versus >90 minutes...
  2. ncbi request reprint Pulmonary embolism as a cause of unexplained sinus tachycardia after right ventricular myocardial infarction
    JingPing Lin
    Cardiac Department, National University Heart Centre, 1E Kent Ridge Road, National University Health System Tower Block, Level 9, Singapore 119228
    Singapore Med J 54:e199-200. 2013
    ..A high index of suspicion is warranted in order to detect this potentially lethal complication. ..
  3. doi request reprint Immigrant status and disparities in health care delivery in patients with myocardial infarction
    Chi Hang Lee
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Int J Cardiol 166:696-701. 2013
    ..We investigated the differences in socioeconomic status and quality health care between Singapore-born citizens and immigrants presenting with ST-segment elevation myocardial infarction (STEMI)...
  4. doi request reprint Adiponectin profile in Asian patients undergoing coronary revascularization and its association with plaque vulnerability: IDEAS-ADIPO study
    Chi Hang Lee
    Department of Medicine, National University of Singapore, Singapore
    Obesity (Silver Spring) 20:2451-7. 2012
    ..Increased serum adiponectin levels were independently associated with increased culprit lesion NC burden, suggesting a role for adiponectin in modulating coronary plaque vulnerability...
  5. doi request reprint Intravascular ultrasound guided percutaneous coronary intervention: a practical approach
    Chi Hang Lee
    Cardiac Department, National University Heart Centre, Singapore
    J Interv Cardiol 25:86-94. 2012
    ..The roles of IVUS in PCI are likely to undergo revolutionary change in the era of plaque characterization and drug-eluting stents...
  6. doi request reprint Correlation between high density lipoprotein-cholesterol and remodeling index in patients with coronary artery disease: IDEAS (IVUS diagnostic evaluation of atherosclerosis in Singapore)-HDL study
    Chi Hang Lee
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Kent Ridge, Singapore
    Int J Cardiovasc Imaging 28:33-41. 2012
    ..023), but not in diabetic, patients (P = 0.707). We found a negative correlation between HDL-cholesterol level and remodeling index. Diabetic status may have an influence on the observed relationship...
  7. doi request reprint Microvascular obstruction after percutaneous coronary intervention
    Chi Hang Lee
    Cardiac Department, National University Heart Center, National University of Singapore, 5, Lower Kent Ridge Road, Singapore 119074
    Catheter Cardiovasc Interv 75:369-77. 2010
    ....
  8. ncbi request reprint Procedure-related myonecrosis after bare and drug-eluting stent implantation
    Chi Hang Lee
    Cardiac Department, National University Heart Center, 5 Lower Kent Ridge Road, Singapore
    Asian Cardiovasc Thorac Ann 18:272-8. 2010
    ..In this study, bare metal stents and the 4 drug-eluting stents were associated with similar low incidences of myonecrosis, myocardial infarction, and large myocardial infarction...
  9. doi request reprint Obstructive sleep apnea in patients admitted for acute myocardial infarction. Prevalence, predictors, and effect on microvascular perfusion
    Chi Hang Lee
    Departments of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Chest 135:1488-95. 2009
    ....
  10. ncbi request reprint Long-term safety and efficacy are observed after implantation of Zotarolimus-Eluting stent in real-world clinical practice
    Chi Hang Lee
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    EuroIntervention 4:338-44. 2008
    ..Zotarolimus-eluting stents (ZESs) have been shown to be safe and effective in randomised trials. We sought to report the clinical outcomes after implantation of ZES in real-world clinical practice...
  11. doi request reprint An intravascular ultrasound study of Cypher, Taxus, and endeavor stents on relation between neointimal proliferation and residual plaque burden
    Chi Hang Lee
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Interv Cardiol 21:519-27. 2008
    ..We investigated the relation between residual plaque burden and neointimal proliferation after drug-eluting stent (DES) implantation...
  12. doi request reprint Shortening of median door-to-balloon time in primary percutaneous coronary intervention in Singapore by simple and inexpensive operational measures: clinical practice improvement program
    Chi Hang Lee
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Interv Cardiol 21:414-23. 2008
    ..Primary percutaneous coronary intervention is the standard reperfusion strategy for ST-segment elevation myocardial infarction in our center. We aimed to shorten the median door-to-balloon time from over 100 minutes to 90 minutes or less...
  13. ncbi request reprint Angiographic no-reflow and six-month mortality in elderly (>/= 75 years old) Asian patients undergoing primary percutaneous coronary intervention: A single center experience from 1998 to 2007
    Chi Hang Lee
    Department of Medicine, National University of Singapore, Singapore
    Acute Card Care 12:63-9. 2010
    ..We sought to report the incidence of angiographic no-reflow and clinical outcomes of elderly patients who have undergone primary percutaneous coronary intervention at a tertiary institution in Singapore over a period of 10 years...
  14. doi request reprint New set of intravascular ultrasound-derived anatomic criteria for defining functionally significant stenoses in small coronary arteries (results from Intravascular Ultrasound Diagnostic Evaluation of Atherosclerosis in Singapore [IDEAS] study)
    Chi Hang Lee
    Department of Medicine, National University of Singapore Yong Loo Lin School of Medicine, Singapore
    Am J Cardiol 105:1378-84. 2010
    ..A minimal lumen area of < or =2.0 mm(2), plaque burden of > or =80%, and lesion length of > or =20 mm predicted a FFR of <0.75 with good sensitivity and specificity...
  15. pmc Severe obstructive sleep apnea and outcomes following myocardial infarction
    Chi Hang Lee
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Clin Sleep Med 7:616-21. 2011
    ..We hypothesized that severe OSA was associated with lower event-free survival rate after ST-segment elevation myocardial infarction (STEMI)...
  16. ncbi request reprint Acute myocardial infarction in young Asian women: a comparative study on Chinese, Malay and Indian ethnic groups
    C B Xie
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, Level 10 NUHS Tower Block, Kent Ridge Road, Singapore 119228
    Singapore Med J 52:835-9. 2011
    ..We present a comprehensive overview of the clinical characteristics of young Asian women with AMI and a comparative analysis among Chinese, Malay and Indian women in a multi-ethnic Asian country...
  17. pmc The relative impact of obstructive sleep apnea and hypertension on the structural and functional changes of the thoracic aorta
    Li Ching Lee
    Cardiac Department, National University Hospital, Singapore, National University Health System, Singapore
    Sleep 33:1173-6. 2010
    ..We aimed to investigate the relative impact of OSA and hypertension on the structural and functional changes of the thoracic aorta...
  18. ncbi request reprint Use of endothelial progenitor cell capture stent (Genous Bio-Engineered R Stent) during primary percutaneous coronary intervention in acute myocardial infarction: intermediate- to long-term clinical follow-up
    Melissa Co
    Cardiac Department, National University Hospital, Singapore, Singapore
    Am Heart J 155:128-32. 2008
    ..We assessed the use of the endothelial progenitor cell (EPC) capture stent in primary percutaneous intervention in ST-elevation myocardial infarction (STEMI)...
  19. doi request reprint Effectiveness and safety of the genous endothelial progenitor cell-capture stent in acute ST-elevation myocardial infarction
    Adrian F Low
    National University Heart Centre, Singapore
    Am J Cardiol 108:202-5. 2011
    ..In conclusion, implantation of the EPC-capture stent during primary angioplasty is associated with a favorable late clinical outcome but with higher than anticipated angiographic late loss...
  20. ncbi request reprint Incidence, predictors, and outcomes of device failure of X-sizer thrombectomy: real-world experience of 200 cases in 5 years
    Chi Hang Lee
    The Heart Institute, Singapore, Singapore
    Am Heart J 153:14.e13-9. 2007
    ..However, patient and lesion subsets were highly selected, and extrapolation of the results to daily practice is problematic...
  21. doi request reprint Clinical predictors of stent thrombosis in the "real world" drug-eluting stent era
    Eduardo L Tin-Hay
    Cardiac Department, National University Hospital, 5 Lower Kent Ridge Road, 119074, Singapore
    Int J Cardiol 145:422-5. 2010
    ..There is however an increased concern with the safety of DES with regard to stent thrombosis (ST). We examined the incidence of ST among patients who received DES and determined the clinical predictors...
  22. ncbi request reprint Procedural success and 30 day outcomes between CYPHER and TAXUS stent implantation for the treatment of bifurcation lesions--a single-center experience
    Chi Hang Lee
    Cardiac Department, National University Hospital, Singapore
    J Invasive Cardiol 18:39-42. 2006
    ..In this registry study, we sought to investigate the procedural success and 30-day outcomes of the patients who were treated with either the CYPHER or TAXUS stents for de novo bifurcation lesions...
  23. ncbi request reprint Inverse relation between diastolic blood pressure and long-term outcomes in patients undergoing pharmacoinvasive therapy for myocardial infarction: the J-shaped relation in the contemporary era of revascularisation
    Chi Hang Lee
    Cardiac Department, National University Hospital, The Heart Institute, Singapore
    J Cardiovasc Med (Hagerstown) 7:806-11. 2006
    ..We sought to re-evaluate this J-shaped relation in the era of pharmacoinvasive therapy...
  24. ncbi request reprint Clinical characteristics and prognostic importance of mild-to-moderate noninfarct-related coronary artery disease in patients with first ST-elevation myocardial infarction
    Wern Miin Soo
    Cardiac Department, National University Heart Centre, NUHS Tower Block, Level 9, 1E Kent Ridge Road, Singapore 119228, Singapore
    Coron Artery Dis 22:55-8. 2011
    ..However, there are limited data on patients with angiographically mild-to-moderate (< 70%) noninfarct-related artery (IRA) stenoses...
  25. ncbi request reprint The influence of timing of polysomnography on diagnosis of obstructive sleep apnea in patients presenting with acute myocardial infarction and stable coronary artery disease
    Ting Ting Low
    Department of Cardiology, National University Heart Centre, Singapore
    Sleep Med 14:985-90. 2013
    ..We aimed to determine if timing of polysomnography (PSG) influences the diagnosis of obstructive sleep apnea (OSA) in acute myocardial infarction (AMI) or stable coronary artery disease (CAD)...
  26. ncbi request reprint Pretreatment with intracoronary adenosine reduces the incidence of myonecrosis after non-urgent percutaneous coronary intervention: a prospective randomized study
    Chi Hang Lee
    Cardiac Department, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074
    Eur Heart J 28:19-25. 2007
    ..We sought to investigate the effect of adenosine pretreatment on the incidence of myonecrosis after non-urgent percutaneous coronary intervention (PCI)...
  27. doi request reprint Angiographic and platelet reactivity outcomes with prasugrel 60 mg pretreatment and clopidogrel 600 mg pretreatment in primary percutaneous coronary intervention
    Yiding Li
    Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
    J Thromb Thrombolysis 34:499-505. 2012
    ..The very high frequency of high on-clopidogrel platelet reactivity with 600 mg of clopidogrel in this Asian STEMI cohort deserves further study...
  28. ncbi request reprint Impact of reversibility of no reflow phenomenon on 30-day mortality following percutaneous revascularization for acute myocardial infarction-insights from a 1,328 patient registry
    Chi Hang Lee
    Cardiac Department, National University Hospital, The Heart Institute, Singapore
    J Interv Cardiol 18:261-6. 2005
    ..Occurrence of no reflow phenomenon during percutaneous coronary intervention (PCI) is associated with increased mortality. Although intracoronary medications can improve coronary flow, the effect on mortality is not known...
  29. ncbi request reprint Predictors of survival after contemporary percutaneous coronary revascularization for acute myocardial infarction in the real world
    Chi Hang Lee
    Cardiac Department, National University Hospital, Level 3, Main Building 5, Lower Kent Ridge Road, Singapore, 119074
    J Invasive Cardiol 16:627-31. 2004
    ..Among patients with cardiogenic shock, similar mortality was observed in patients with anterior myocardial infarction (MI) or inferior MI with/without right ventricle involvement...
  30. ncbi request reprint Reperfusion strategy and mortality in ST-elevation myocardial infarction among patients with and without impaired renal function
    Mark Y Chan
    National University Heart Centre, Singapore, Singapore
    Ann Acad Med Singapore 39:179-84. 2010
    ..Whether this benefit extends to patients with impaired renal function is uncertain...
  31. ncbi request reprint Everolimus-eluting bioresorbable vascular scaffold (BVS) implantation in patients with ST-segment elevation myocardial infarction (STEMI)
    Takashi Kajiya
    Cardiac Department, National University Heart Centre Singapore, Singapore
    EuroIntervention 9:501-4. 2013
    ..We assessed the safety and impact of BVS in the setting of primary percutaneous coronary intervention (PCI) in patients presenting with STEMI to our institution...
  32. ncbi request reprint A single-center experience of transitioning from a routine transfemoral to a transradial intervention approach in ST-elevation myocardial infarction: Impact on door-to-balloon time and clinical outcomes
    Takashi Kajiya
    Cardiac Department, National University Heart Centre Singapore, Singapore
    J Cardiol 62:12-7. 2013
    ..Because of the greater technical complexity of TRI, a potential compromise in door-to-balloon (DTB) time remains a major concern of centers adopting TRI for STEMI...
  33. ncbi request reprint Lethal presentations of coronary artery spasm after an event-free period of six years following initial diagnosis
    Chi Hang Lee
    Interventional Cardiologist, Cardiology Department, National University Hospital, Level 3, Main Building, 5, Lower Kent Ridge Road, 119074, Singapore
    J Invasive Cardiol 20:E30-2. 2008
    ..In view of the recurrent coronary artery spasm causing myocardial infarction and ventricular fibrillation, an implantable cardioverter defibrillator was implanted. The patient was well at 2-month follow up...
  34. doi request reprint CYP2C19 and PON1 polymorphisms regulating clopidogrel bioactivation in Chinese, Malay and Indian subjects
    Mark Y Chan
    National University Heart Centre, 1E Kent Ridge Road, Singapore 119228, Singapore
    Pharmacogenomics 13:533-42. 2012
    ....
  35. ncbi request reprint Impact of glycemic control on occurrence of no-reflow and 30-day outcomes in diabetic patients undergoing primary angioplasty for myocardial infarction
    Chi Hang Lee
    Cardiac Department, National University Hospital, Level 3, Main Building, 5 Lower Kent Ridge Road, Singapore 119074
    J Invasive Cardiol 17:422-6. 2005
    ..695) rates similar to the suboptimal glycemic control group. Among diabetic patients undergoing primary angioplasty, optimal glycemic control was not associated with a lesser occurrence of no-reflow or better 30-day outcomes...
  36. ncbi request reprint Safety of combination therapy with milrinone and esmolol for heart protection during percutaneous coronary intervention in acute myocardial infarction
    Kian Keong Poh
    Cardiac Department, National University Heart Center, National University Health System, 1E Kent Ridge Rd, NUHS Tower Block, Level 9, Singapore, 19228, Singapore
    Eur J Clin Pharmacol 70:527-30. 2014
    ..The present study tested the safety of combination therapy of milrinone and esmolol (M + E) in patients with AMI...
  37. doi request reprint Myocardial infarction in singapore: ethnic variation in evidence-based therapy and its association with socioeconomic status, social network size and perceived stress level
    Thet Hein
    Cardiac Department, National University Heart Centre, Singapore Electronic address
    Heart Lung Circ 22:1011-7. 2013
    ..We also examined its association with socioeconomic level and social network size and the influence on psychological stress level...
  38. doi request reprint Clinical experience of StarClose vascular closure device in patients with first and recurrent femoral punctures
    Edgar Lik Wui Tay
    Cardiac Department, National University Hospital, Singapore
    J Interv Cardiol 21:67-73. 2008
    ..We present our clinical experience of StarClose in patients undergoing coronary interventions, including its use in patients after repeated puncture of the same femoral access site...
  39. ncbi request reprint Update on drug-eluting stents for prevention of restenosis
    Chi Hang Lee
    Cardiac Department, National University Hospital, Singapore
    Asian Cardiovasc Thorac Ann 14:75-82. 2006
    ..Results including cost-benefit analyses are expected to have a tremendous impact on the practice of interventional cardiology in the next decade...
  40. ncbi request reprint Free coronary perforation after X-Sizer thrombectomy: experience of two cases and review of the literature
    Chi Hang Lee
    Cardiac Department, National University Hospital, Level 3, Main Building, Lower Kent Ridge Road, Singapore 119074
    J Invasive Cardiol 17:445-8. 2005
  41. ncbi request reprint Determination of the severity of underlying lesions in acute myocardial infarction on the basis of collateral vessel development
    Vanessa Khoo
    aDepartment of Cardiology, National University Heart Centre bBiostatistics Unit, National University Health System cDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
    Coron Artery Dis 25:493-7. 2014
    ..Because the development of collateral vessels is an indication of ischemia, their presence was used as a surrogate marker for the existence of a high-grade lesion...
  42. ncbi request reprint Direct stenting compared to conventional stenting in Diabetic Patients Undergoing Elective Angioplasty for Coronary Artery Disease (DECIDE): a multicenter, open label, randomized, controlled efficacy study
    Huay Cheem Tan
    Cardiac Department, National University Hospital, Level 3, Main Building, 5 Lower Kent Ridge Road, Singapore 119074
    Am Heart J 148:1007-11. 2004
    ..Whether DS confers benefit in diabetic patients, who have been shown to have high restenosis risk after stent implantation, remains unknown...
  43. ncbi request reprint Prognostic implication of obstructive sleep apnea diagnosed by post-discharge sleep study in patients presenting with acute coronary syndrome
    Germaine Loo
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Sleep Med 15:631-6. 2014
    ..We aimed to determine the prognostic implications of obstructive sleep apnea (OSA) diagnosed during the recovery phase of acute coronary syndrome (ACS)...
  44. pmc Excessive daytime sleepiness is associated with longer culprit lesion and adverse outcomes in patients with coronary artery disease
    Chi Hang Lee
    Department of Cardiology, National University Heart Centre, Singapore Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, Singapore
    J Clin Sleep Med 9:1267-72. 2013
    ..We assessed whether excessive daytime sleepiness was associated with coronary plaque phenotype and subsequent adverse cardiovascular events...
  45. doi request reprint Endothelial progenitor cell capture stent: safety and effectiveness
    Rishi Sethi
    Cardiac Department, National University Heart Centre, Singapore
    J Interv Cardiol 25:493-500. 2012
    ..Data from animal studies have been encouraging. The first-in-man study of the Combo stent has been completed and results were presented...
  46. ncbi request reprint Safety and feasibility of X-sizer-facilitated rescue percutaneous coronary intervention: a preliminary experience
    Chi Hang Lee
    Cardiac Department, National University Hospital, Singapore
    J Invasive Cardiol 17:1-4. 2005
    ..In conclusion, X-Sizer-facilitated rescue PCI was safe and feasible. The outcomes of patients who underwent X-Sizer-facilitated rescue PCI were similar to those who underwent X-Sizer-facilitated primary PCI...
  47. ncbi request reprint Incidence and predictors of side-branch compromise in primary percutaneous coronary intervention for acute myocardial infarction
    Valerie Khoo
    National University Hospital Cardiac Department, Level 3, Main Building, National University Hospital, 5, Lower Kent Ridge Road, Singapore
    J Invasive Cardiol 26:297-302. 2014
    ..We aimed to determine the incidence and predictors of side-branch compromise (SBC) in patients who underwent primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI)...
  48. ncbi request reprint Acute myocardial infarction in pregnant women
    Chin Leng Poh
    National University Heart Centre, National University of Singapore, Singapore
    Ann Acad Med Singapore 39:247-53. 2010
    ..This paper serves to review available literature regarding an extensive range of management issues that directly impact on maternal and fetal outcomes...