Anthony Y C Kuk

Summary

Affiliation: National University of Singapore
Country: Singapore

Publications

  1. ncbi request reprint Test of marginal compatibility and smoothing methods for exchangeable binary data with unequal cluster sizes
    Zhen Pang
    Department of Statistics and Applied Probability, National University of Singapore, Singapore
    Biometrics 63:218-27. 2007
  2. doi request reprint A fast collapsed data method for estimating haplotype frequencies from pooled genotype data with applications to the study of rare variants
    Anthony Y C Kuk
    Department of Statistics and Applied Probability, National University of Singapore, Singapore 117546, Singapore
    Stat Med 32:1343-60. 2013
  3. ncbi request reprint The estimation of SARS incubation distribution from serial interval data using a convolution likelihood
    Anthony Y C Kuk
    Department of Statistics and Applied Probability, National University of Singapore
    Stat Med 24:2525-37. 2005
  4. doi request reprint Computationally feasible estimation of haplotype frequencies from pooled DNA with and without Hardy-Weinberg equilibrium
    Anthony Y C Kuk
    Department of Statistics and Applied Probability, National University of Singapore, Singapore 117546
    Bioinformatics 25:379-86. 2009
  5. doi request reprint A study of the efficiency of pooling in haplotype estimation
    Anthony Y C Kuk
    Department of Statistics and Applied Probability, National University of Singapore, 117546 Singapore
    Bioinformatics 26:2556-63. 2010
  6. doi request reprint Recursive subsetting to identify patients in the STAR*D: a method to enhance the accuracy of early prediction of treatment outcome and to inform personalized care
    Anthony Y C Kuk
    Department of Statistics and Applied Probability, National University of Singapore, 6 Science Drive 2, Singapore 117546
    J Clin Psychiatry 71:1502-8. 2010
  7. pmc An EM algorithm based on an internal list for estimating haplotype distributions of rare variants from pooled genotype data
    Anthony Y C Kuk
    Department of Statistics and Applied Probability, National University of Singapore, Singapore, 117546, Singapore
    BMC Genet 14:82. 2013
  8. ncbi request reprint A stepwise likelihood ratio test procedure for rare variant selection in case-control studies
    Anthony Y C Kuk
    Department of Statistics and Applied Probability, National University of Singapore, Singapore, Singapore
    J Hum Genet 59:198-205. 2014
  9. ncbi request reprint Determination of the unknown age at first capture of western rock lobsters (Panulirus cygnus) by random effects model
    Yuk W Cheng
    Western Australian Centre of Excellence in Industrial Optimisation, Curtin University of Technology, Perth, Australia
    Biometrics 58:459-62. 2002

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Test of marginal compatibility and smoothing methods for exchangeable binary data with unequal cluster sizes
    Zhen Pang
    Department of Statistics and Applied Probability, National University of Singapore, Singapore
    Biometrics 63:218-27. 2007
    ..The proposed methods are illustrated using several data sets and the sampling and robustness properties of the resulting estimators are evaluated by simulations...
  2. doi request reprint A fast collapsed data method for estimating haplotype frequencies from pooled genotype data with applications to the study of rare variants
    Anthony Y C Kuk
    Department of Statistics and Applied Probability, National University of Singapore, Singapore 117546, Singapore
    Stat Med 32:1343-60. 2013
    ..This is more parsimonious than the 12 variants selected by a recently proposed covering method. From another set of 32 rare variants around the FAAH gene, we discover an interesting potential interaction between two of them...
  3. ncbi request reprint The estimation of SARS incubation distribution from serial interval data using a convolution likelihood
    Anthony Y C Kuk
    Department of Statistics and Applied Probability, National University of Singapore
    Stat Med 24:2525-37. 2005
    ..It is possible to obtain an even more efficient estimate by using the combined data but the improvement is not substantial...
  4. doi request reprint Computationally feasible estimation of haplotype frequencies from pooled DNA with and without Hardy-Weinberg equilibrium
    Anthony Y C Kuk
    Department of Statistics and Applied Probability, National University of Singapore, Singapore 117546
    Bioinformatics 25:379-86. 2009
    ..The resulting estimates are, however, not maximum likelihood estimates and hence not optimal. Furthermore, the assumption of Hardy-Weinberg equilibrium (HWE) made may not be realistic in practice...
  5. doi request reprint A study of the efficiency of pooling in haplotype estimation
    Anthony Y C Kuk
    Department of Statistics and Applied Probability, National University of Singapore, 117546 Singapore
    Bioinformatics 26:2556-63. 2010
    ..In fact, the limited evidence given so far is based on simulation studies with small numbers of loci. With rapid advance in technology, it is of interest to see if pooling is still efficient when the number of loci increases...
  6. doi request reprint Recursive subsetting to identify patients in the STAR*D: a method to enhance the accuracy of early prediction of treatment outcome and to inform personalized care
    Anthony Y C Kuk
    Department of Statistics and Applied Probability, National University of Singapore, 6 Science Drive 2, Singapore 117546
    J Clin Psychiatry 71:1502-8. 2010
    ..We explored the possibility of using baseline features and early symptom change to predict which patients will and which patients will not respond to treatment...
  7. pmc An EM algorithm based on an internal list for estimating haplotype distributions of rare variants from pooled genotype data
    Anthony Y C Kuk
    Department of Statistics and Applied Probability, National University of Singapore, Singapore, 117546, Singapore
    BMC Genet 14:82. 2013
    ..There is, however, the danger of using an incorrect list, and there may not be enough database information to form a list externally in some applications...
  8. ncbi request reprint A stepwise likelihood ratio test procedure for rare variant selection in case-control studies
    Anthony Y C Kuk
    Department of Statistics and Applied Probability, National University of Singapore, Singapore, Singapore
    J Hum Genet 59:198-205. 2014
    ..When the proposed procedure is applied to identify rare variants associated with obesity, it identifies one additional variant not picked up by existing methods...
  9. ncbi request reprint Determination of the unknown age at first capture of western rock lobsters (Panulirus cygnus) by random effects model
    Yuk W Cheng
    Western Australian Centre of Excellence in Industrial Optimisation, Curtin University of Technology, Perth, Australia
    Biometrics 58:459-62. 2002
    ..A comparison between this model and the Fabens growth equation is given. The proposed method is a flexible method and can be applied to fit different growth equations when the age at first capture is unknown...