Steven Graham

Summary

Affiliation: National University of Singapore
Country: Singapore

Publications

  1. pmc Effects of the Neurogranin Variant rs12807809 on Thalamocortical Morphology in Schizophrenia
    Jamie Yu Jin Thong
    Department of Bioengineering, National University of Singapore, Singapore
    PLoS ONE 8:e85603. 2013
  2. pmc Executive functions of six-year-old boys with normal birth weight and gestational age
    Desiree Yee Ling Phua
    Singapore Institute for Clinical Sciences, The Agency for Science, Technology and Research, Singapore, Singapore
    PLoS ONE 7:e36502. 2012
  3. pmc Regionally specific white matter disruptions of fornix and cingulum in schizophrenia
    Muhammad Farid Abdul-Rahman
    Division of Bioengineering, National University of Singapore, Singapore, Singapore
    PLoS ONE 6:e18652. 2011
  4. pmc Population differences in brain morphology and microstructure among Chinese, Malay, and Indian neonates
    Jordan Bai
    Department of Bioengineering, National University of Singapore, Singapore, Singapore
    PLoS ONE 7:e47816. 2012
  5. pmc CSF and brain structural imaging markers of the Alzheimer's pathological cascade
    Xianfeng Yang
    Department of Bioengineering, National University of Singapore, Singapore, Singapore
    PLoS ONE 7:e47406. 2012
  6. pmc Maternal anxiety and infants' hippocampal development: timing matters
    A Qiu
    1 Department of Bioengineering, National University of Singapore, Singapore 2 Clinical Imaging Research Centre, National University of Singapore, Singapore 3 Singapore Institute for Clinical Sciences, The Agency for Science, Technology and Research, Singapore
    Transl Psychiatry 3:e306. 2013
  7. pmc Age-related decline in associative learning in healthy Chinese adults
    Annie Lee
    Department of Biomedical Engineering, National University of Singapore, Singapore, Singapore
    PLoS ONE 8:e80648. 2013
  8. pmc Arcuate fasciculus abnormalities and their relationship with psychotic symptoms in schizophrenia
    Muhammad Farid Abdul-Rahman
    Division of Bioengineering, National University of Singapore, Singapore
    PLoS ONE 7:e29315. 2012
  9. ncbi request reprint Amygdala-hippocampal shape and cortical thickness abnormalities in first-episode schizophrenia and mania
    A Qiu
    Department of Bioengineering, National University of Singapore, Singapore
    Psychol Med 43:1353-63. 2013
  10. doi request reprint Morphology and microstructure of subcortical structures at birth: a large-scale Asian neonatal neuroimaging study
    Anqi Qiu
    Department of Bioengineering, National University of Singapore, Singapore
    Neuroimage 65:315-23. 2013

Collaborators

Detail Information

Publications34

  1. pmc Effects of the Neurogranin Variant rs12807809 on Thalamocortical Morphology in Schizophrenia
    Jamie Yu Jin Thong
    Department of Bioengineering, National University of Singapore, Singapore
    PLoS ONE 8:e85603. 2013
    ..These findings help to clarify underlying NRGN mediated pathophysiological mechanisms involving cortical-subcortical brain networks in schizophrenia. ..
  2. pmc Executive functions of six-year-old boys with normal birth weight and gestational age
    Desiree Yee Ling Phua
    Singapore Institute for Clinical Sciences, The Agency for Science, Technology and Research, Singapore, Singapore
    PLoS ONE 7:e36502. 2012
    ..Hence, even among boys born at term with normal birth weight, variations in fetal growth and maturity showed distinct effects on specific executive functions...
  3. pmc Regionally specific white matter disruptions of fornix and cingulum in schizophrenia
    Muhammad Farid Abdul-Rahman
    Division of Bioengineering, National University of Singapore, Singapore, Singapore
    PLoS ONE 6:e18652. 2011
    ....
  4. pmc Population differences in brain morphology and microstructure among Chinese, Malay, and Indian neonates
    Jordan Bai
    Department of Bioengineering, National University of Singapore, Singapore, Singapore
    PLoS ONE 7:e47816. 2012
    ..The population-related brain regions highlighted in our study are key anatomical substrates associated with sensorimotor functions...
  5. pmc CSF and brain structural imaging markers of the Alzheimer's pathological cascade
    Xianfeng Yang
    Department of Bioengineering, National University of Singapore, Singapore, Singapore
    PLoS ONE 7:e47406. 2012
    ..In particular, the volumetric information may be good for the early stage of AD, while morphological shapes should be considered as markers in the prediction of MCI conversion to AD together with the CSF markers...
  6. pmc Maternal anxiety and infants' hippocampal development: timing matters
    A Qiu
    1 Department of Bioengineering, National University of Singapore, Singapore 2 Clinical Imaging Research Centre, National University of Singapore, Singapore 3 Singapore Institute for Clinical Sciences, The Agency for Science, Technology and Research, Singapore
    Transl Psychiatry 3:e306. 2013
    ....
  7. pmc Age-related decline in associative learning in healthy Chinese adults
    Annie Lee
    Department of Biomedical Engineering, National University of Singapore, Singapore, Singapore
    PLoS ONE 8:e80648. 2013
    ..These results show that age effects on associative learning are independent of other cognitive processes involved in PAL. ..
  8. pmc Arcuate fasciculus abnormalities and their relationship with psychotic symptoms in schizophrenia
    Muhammad Farid Abdul-Rahman
    Division of Bioengineering, National University of Singapore, Singapore
    PLoS ONE 7:e29315. 2012
    ....
  9. ncbi request reprint Amygdala-hippocampal shape and cortical thickness abnormalities in first-episode schizophrenia and mania
    A Qiu
    Department of Bioengineering, National University of Singapore, Singapore
    Psychol Med 43:1353-63. 2013
    ..Method Structural magnetic resonance imaging (MRI) was performed on 28 FES patients, 28 FEM patients and 28 healthy control subjects who were matched for age, gender and handedness...
  10. doi request reprint Morphology and microstructure of subcortical structures at birth: a large-scale Asian neonatal neuroimaging study
    Anqi Qiu
    Department of Bioengineering, National University of Singapore, Singapore
    Neuroimage 65:315-23. 2013
    ....
  11. doi request reprint Inattention and hyperactivity predict alterations in specific neural circuits among 6-year-old boys
    Anqi Qiu
    National University of Singapore, 9 Engineering Drive 1, Singapore
    J Am Acad Child Adolesc Psychiatry 51:632-41. 2012
    ....
  12. pmc Principal component based diffeomorphic surface mapping
    Anqi Qiu
    Department of Bioengineering and Clinical Imaging Research Center, National University of Singapore, 117574 Singapore
    IEEE Trans Med Imaging 31:302-11. 2012
    ..We then validate the mapping accuracy and show robustness to outliers whose shape variation is not incorporated into the shape prior...
  13. ncbi request reprint Hippocampal-cortical structural connectivity disruptions in schizophrenia: an integrated perspective from hippocampal shape, cortical thickness, and integrity of white matter bundles
    Anqi Qiu
    Division of Bioengineering, National University of Singapore, Singapore
    Neuroimage 52:1181-9. 2010
    ..Our findings suggested that aberrant structural hippocampal-cortical connectivities may serve as a marker of the illness and provide further structural evidence to support the notion of schizophrenia as a disorder of brain connectivity...
  14. ncbi request reprint Basal ganglia shapes predict social, communication, and motor dysfunctions in boys with autism spectrum disorder
    Anqi Qiu
    Division of Bioengineering and Clinical Imaging Research Center, National University of Singapore and Singapore Institute for Clinical Sciences, Singapore
    J Am Acad Child Adolesc Psychiatry 49:539-51, 551.e1-4. 2010
    ..Our objective was to investigate basal ganglia shape abnormalities and their association with behavioral features of ASD, which may involve multiple frontal-subcortical circuits...
  15. pmc Surface-based analysis on shape and fractional anisotropy of white matter tracts in Alzheimer's disease
    Anqi Qiu
    Division of Bioengineering, National University of Singapore, Singapore, Singapore
    PLoS ONE 5:e9811. 2010
    ..Diffusion tensor imaging (DTI), which has been widely used in AD studies, obtains new insights into the white matter structure...
  16. pmc Atlas generation for subcortical and ventricular structures with its applications in shape analysis
    Anqi Qiu
    Division of Bioengineering, National University of Singapore, Singapore 117576
    IEEE Trans Image Process 19:1539-47. 2010
    ..In shape-based classification, the metric distances between subjects and each of within-class estimated atlases construct a shape feature space, which allows for performing a variety of classification algorithms to distinguish anatomies...
  17. pmc Basal ganglia volume and shape in children with attention deficit hyperactivity disorder
    Anqi Qiu
    Division of Bioengineering, National University of Singapore, 7 Engineering Dr 1, Block E3A 04 15, Singapore
    Am J Psychiatry 166:74-82. 2009
    ..To specify localization of these abnormalities, large deformation diffeomorphic metric mapping (LDDMM) was used to examine the effects of ADHD, sex, and their interaction on basal ganglia shapes...
  18. pmc APOE related hippocampal shape alteration in geriatric depression
    Anqi Qiu
    Division of Bioengineering, National University of Singapore, Singapore
    Neuroimage 44:620-6. 2009
    ..Thus, hippocampal shape abnormalities in late-onset depressed patients with one apoE E4 may indicate future conversion of this group to AD at higher risk than depressed patients without the apoE E4...
  19. pmc Parallel transport in diffeomorphisms distinguishes the time-dependent pattern of hippocampal surface deformation due to healthy aging and the dementia of the Alzheimer's type
    Anqi Qiu
    Division of Bioengineering, National University of Singapore, 7 Engineering Drive 1, Singapore, Singapore
    Neuroimage 40:68-76. 2008
    ..77 and 0.87, which were obtained in the same training set using the leave-one-out cross validation approach...
  20. pmc Time sequence diffeomorphic metric mapping and parallel transport track time-dependent shape changes
    Anqi Qiu
    Division of Bioengineering, National University of Singapore, Singapore
    Neuroimage 45:S51-60. 2009
    ....
  21. ncbi request reprint Multi-structure network shape analysis via normal surface momentum maps
    Anqi Qiu
    Division of Bioengineering, National University of Singapore, Singapore
    Neuroimage 42:1430-8. 2008
    ....
  22. pmc Regional shape abnormalities in mild cognitive impairment and Alzheimer's disease
    Anqi Qiu
    Division of Bioengineering, National University of Singapore, Singapore
    Neuroimage 45:656-61. 2009
    ..Although the locations of the shape abnormalities in MCI and AD are primarily within the mesial temporal region, analyses support distinct components of correlated shape variation that may help predict future MCI conversion...
  23. ncbi request reprint Intrinsic and extrinsic analysis in computational anatomy
    Anqi Qiu
    Division of Bioengineering, National University of Singapore, Singapore
    Neuroimage 39:1803-14. 2008
    ..Both methods show that the left cingulate gyrus tends to become thinner in schizophrenia relative to the healthy control population. However, the intrinsic method increases the statistical power...
  24. ncbi request reprint Combined analyses of thalamic volume, shape and white matter integrity in first-episode schizophrenia
    Anqi Qiu
    Division of Bioengineering, National University of Singapore, Singapore
    Neuroimage 47:1163-71. 2009
    ....
  25. pmc Neuroanatomical asymmetry patterns in individuals with schizophrenia and their non-psychotic siblings
    Anqi Qiu
    Division of Bioengineering, National University of Singapore, Singapore
    Neuroimage 47:1221-9. 2009
    ..These altered patterns of asymmetries are present in subjects with schizophrenia and their siblings, and therefore may represent a schizophrenia-related endophenotype...
  26. doi request reprint Birth weight and gestation influence striatal morphology and motor response in normal six-year-old boys
    Anqi Qiu
    Division of Bioengineering, National University of Singapore, Singapore, Singapore
    Neuroimage 59:1065-70. 2012
    ....
  27. ncbi request reprint Recognition memory for studied words is determined by cortical activation differences at encoding but not during retrieval
    Michael W L Chee
    Cognitive Neuroscience Laboratory, SingHealth Research Laboratories, Singapore, Singapore
    Neuroimage 22:1456-65. 2004
    ..This observation is consistent with a dual process account of episodic memory...
  28. doi request reprint Role of medial cortical, hippocampal and striatal interactions during cognitive set-shifting
    Steven Graham
    Functional Brain Imaging Lab, Department of Psychology, National University of Singapore, Block AS5, 04 16, 7 Arts Link, Singapore 117570, Singapore
    Neuroimage 45:1359-67. 2009
    ....
  29. pmc IQ-related fMRI differences during cognitive set shifting
    Steven Graham
    Functional Brain Imaging Lab, Department of Psychology, National University of Singapore, Singapore 117570
    Cereb Cortex 20:641-9. 2010
    ..One implication is that caution must be exercised when drawing conclusions from differences in activation between groups of individuals in whom IQ may differ (e.g., psychiatric vs. control samples)...
  30. doi request reprint Simultaneous backward conditioned inhibition and mediated conditioning
    Steven Graham
    Department of Psychology, National University of Singapore, Singapore 117570, USA
    J Exp Psychol Anim Behav Process 37:241-5. 2011
    ....
  31. doi request reprint The past tense debate: is phonological complexity the key to the puzzle?
    Tomasina M Oh
    Department of English Language and Literature, National University of Singapore, Singapore
    Neuroimage 57:271-80. 2011
    ..Temporal lobe regions and left hippocampus were among regions activated relatively more for irregular verb inflection. These latter findings suggest it may be premature to rule out a dual system account...
  32. ncbi request reprint Enhanced selective memory consolidation following post-learning pleasant and aversive arousal
    Denise Li Juan Liu
    Department of Psychology, National University of Singapore, Block AS4, 02 07, 9 Arts Link, Singapore 117570, Singapore
    Neurobiol Learn Mem 89:36-46. 2008
    ..The study has implications for the understanding of healthy and pathological cognitive-affective processes in humans...
  33. doi request reprint Reproducibility of brain tissue volumes in longitudinal studies: effects of changes in signal-to-noise ratio and scanner software
    Borys Shuter
    Department of Diagnostic Radiology, National University of Singapore, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
    Neuroimage 41:371-9. 2008
    ..It was concluded that SNR changes significantly influence SPM5-derived GM volumes. SNR may be influenced by scanner software upgrades and hardware condition and should be routinely assessed in studies of brain volume...
  34. ncbi request reprint Word frequency and subsequent memory effects studied using event-related fMRI
    Michael W L Chee
    Cognitive Neuroscience Laboratory, Singapore General Hospital, Singapore, 169611, Singapore
    Neuroimage 20:1042-51. 2003
    ..These findings suggest the specific brain regions where less commonly encountered words are processed in a manner that facilitates their subsequent recognition...