Yin Bin Cheung

..The aim is to convince both parties the importance of a truly collaborative effort...

..This may translate into differences in discriminative ability and sample size requirement...

..The reasons and implications of the absence of an order effect are discussed. We conclude that presentation order is unlikely to alter the responses to the two HRQoL instruments...

..To assess the relation between birthweight and psychological distress as measured by the Malaise Inventory in adult twins...

..All of the definitions are valid when used and interpreted correctly. The choice of which definition to adopt depends on the specific issues one attempts to address. Calls for abandoning the conventional definitions are not justified...

..Furthermore, bilingual and monolingual persons may differ in cognition and responses to questionnaires...

..The shortening of established health-related quality of life instruments should be considered in order to reduce the burden of having patients to answer lengthy questionnaires...

..We modified its visual analogue scale (VAS) to an ordered categorical scale and changed some of the wording in the instrument. This study examined the measurement properties of the modified FLIC...

..It is concluded that the shortening of established health-related quality of life instruments is viable in oncology research...

..The relative survival approach agrees with the Cox model with age as the time scale. We maintain that a careful clarification of research purpose and a careful choice of methods are necessary...

..To test the hypothesis that birth weight for gestational age and weight gain in early childhood have a long term association with psychological distress in adults...

..The results support the hypothesis of a biological link between perinatal factors and psychological distress in adults. The strengths of the associations were compared with those between the outcome and adult correlates...

..Previous studies of its factor structure were often based on samples of young persons and on exploratory factor analysis techniques. The results varied from suggesting one to three factors...

..The usual approach of recording and analysing the milestone as a binary outcome, such as whether the child can build a tower of three cubes, may leave out important information...

..037) relation between birth weight and mental health than an ordinary probit regression model (P = 0.170). Interpretation and practical considerations are discussed...

..The median PFS was 8 months and median OS was 17 months. The regimen was tolerable, with a 21% grade 3/4 neutropenia rate and 38% grade 2/3 esophagitis rate...

..The objective of the current study was to assess the efficacy of a 3-drug combination followed by maintenance treatment in patients with metastatic NPC...

..Across all stages HPV and EBV staining was absent from all tissues examined. It is unlikely that HPV or EBV is an important etiological agent in adenocarcinoma of the lung, even among the never-smokers...

..We aimed to assess the expression of female hormone receptors in East-Asian lung adenocarcinomas, their correlation with EGFR mutations, and prognostic significance...

..The survival and epidemiology of small-cell lung cancer (SCLC) in Singapore has not been described. We aim to present the characteristics as well as determine the survival outcome and important prognostic factors for SCLC patients...

..We aimed to evaluate tolerability and efficacy of three single-agent regimens in these patients...

..05-5.31; p=0.037) compared to the men. Our findings suggest that cumulative smoking exposure in terms of pack-years smoked is an important determining factor for the preferred development of SCLC among smokers...

..It is increasingly being recognized that never-smokers can be afflicted with non-small-cell lung cancer (NSCLC). We aim to assess survival differences between smokers and never-smokers with NSCLC...

..We postulate a possible pathophysiology for the association between breast edema and malignant pleural effusion. The principle of management when one encounters similar cases would be to treat the underlying pleural effusion...

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..In this paper, we review the pemetrexed-gemcitabine combination in the treatment of NSCLC patients with regards to the rationale, clinical activity as well as the future directions for this new 2-drug combination...

..Unless we eliminate tobacco smoking completely, lung cancer will continue its wrath into the 21st century...