Research Topics

Shunsuke Chiba

Summary

Affiliation: Nanyang Technological University
Country: Singapore

Publications

  1. Ariyasu S, Too P, Mu J, Goh C, Ding Y, Tnay Y, et al. Glycopeptide antibiotic analogs for selective inactivation and two-photon imaging of vancomycin-resistant strains. Chem Commun (Camb). 2016;52:4667-70 pubmed publisher
    ..Moreover, this theranostic analog can be also applied for selective two-photon fluorescence imaging of Gram (+) bacteria. ..
  2. Lonca G, Tejo C, Chan H, Chiba S, Gagosz F. Gold(i)-catalyzed 6-endo-dig azide-yne cyclization: efficient access to 2H-1,3-oxazines. Chem Commun (Camb). 2017;53:736-739 pubmed publisher
    ..Molecular transformations of the as-prepared 2H-1,3-oxazines were also investigated. ..
  3. Zhu X, Chiba S. Copper-catalyzed oxidative carbon-heteroatom bond formation: a recent update. Chem Soc Rev. 2016;45:4504-23 pubmed publisher
    ..This review updates recent advances in Cu-catalyzed (anaerobic) oxidative carbon-heteroatom bond formation on sp(3)- and sp(2)-C-H bonds as well as alkenes, classified according to the types of stoichiometric oxidants. ..
  4. Chen H, Kaga A, Chiba S. anti-Selective aminofluorination of alkenes with amidines mediated by hypervalent iodine(iii) reagents. Org Biomol Chem. 2016;14:5481-5 pubmed publisher
    ..Further reductive ring-opening of the 2-imidazoline moiety could deliver highly functionalized 3-fluoropropane-1,2-diamine derivatives. ..
  5. Kaga A, Peng X, Hirao H, Chiba S. Diastereo-Divergent Synthesis of Saturated Azaheterocycles Enabled by tBuOK-Mediated Hydroamination of Alkenyl Hydrazones. Chemistry. 2015;21:19112-8 pubmed publisher
    ..By contrast, 2,5-trans selectivity was observed when an isopropyl group was used as the substituent on hydrazones. An unusual 2,6-trans selectivity in piperidine formation was also realized using the present strategy. ..
  6. Zhu X, Chiba S. Construction of 1-pyrroline skeletons by Lewis acid-mediated conjugate addition of vinyl azides. Chem Commun (Camb). 2016;52:2473-6 pubmed publisher
    ..The reactions of vinyl azides with 3-alkylidene-2-oxoindolines afford 3',4'-dihydrospiro[indoline-3,2'-pyrrol]-2-ones in a diastereoselective fashion, whereas those with dimethyl 2-alkylidenemalonates provide 4,5-dihydro-3H-pyrroles. ..
  7. Too P, Chan G, Tnay Y, Hirao H, Chiba S. Hydride Reduction by a Sodium Hydride-Iodide Composite. Angew Chem Int Ed Engl. 2016;55:3719-23 pubmed publisher
    ..This remarkably simple protocol endows NaH with unprecedented and unique hydride-donor chemical reactivity. ..
  8. Tejo C, Pang J, Ong D, Oi M, Uchiyama M, Takita R, et al. Dearylation of arylphosphine oxides using a sodium hydride-iodide composite. Chem Commun (Camb). 2018;54:1782-1785 pubmed publisher
    ..The transient sodium phosphinite could be functionalized with a range of electrophiles in a one-pot fashion. ..

Detail Information

Publications8

  1. Ariyasu S, Too P, Mu J, Goh C, Ding Y, Tnay Y, et al. Glycopeptide antibiotic analogs for selective inactivation and two-photon imaging of vancomycin-resistant strains. Chem Commun (Camb). 2016;52:4667-70 pubmed publisher
    ..Moreover, this theranostic analog can be also applied for selective two-photon fluorescence imaging of Gram (+) bacteria. ..
  2. Lonca G, Tejo C, Chan H, Chiba S, Gagosz F. Gold(i)-catalyzed 6-endo-dig azide-yne cyclization: efficient access to 2H-1,3-oxazines. Chem Commun (Camb). 2017;53:736-739 pubmed publisher
    ..Molecular transformations of the as-prepared 2H-1,3-oxazines were also investigated. ..
  3. Zhu X, Chiba S. Copper-catalyzed oxidative carbon-heteroatom bond formation: a recent update. Chem Soc Rev. 2016;45:4504-23 pubmed publisher
    ..This review updates recent advances in Cu-catalyzed (anaerobic) oxidative carbon-heteroatom bond formation on sp(3)- and sp(2)-C-H bonds as well as alkenes, classified according to the types of stoichiometric oxidants. ..
  4. Chen H, Kaga A, Chiba S. anti-Selective aminofluorination of alkenes with amidines mediated by hypervalent iodine(iii) reagents. Org Biomol Chem. 2016;14:5481-5 pubmed publisher
    ..Further reductive ring-opening of the 2-imidazoline moiety could deliver highly functionalized 3-fluoropropane-1,2-diamine derivatives. ..
  5. Kaga A, Peng X, Hirao H, Chiba S. Diastereo-Divergent Synthesis of Saturated Azaheterocycles Enabled by tBuOK-Mediated Hydroamination of Alkenyl Hydrazones. Chemistry. 2015;21:19112-8 pubmed publisher
    ..By contrast, 2,5-trans selectivity was observed when an isopropyl group was used as the substituent on hydrazones. An unusual 2,6-trans selectivity in piperidine formation was also realized using the present strategy. ..
  6. Zhu X, Chiba S. Construction of 1-pyrroline skeletons by Lewis acid-mediated conjugate addition of vinyl azides. Chem Commun (Camb). 2016;52:2473-6 pubmed publisher
    ..The reactions of vinyl azides with 3-alkylidene-2-oxoindolines afford 3',4'-dihydrospiro[indoline-3,2'-pyrrol]-2-ones in a diastereoselective fashion, whereas those with dimethyl 2-alkylidenemalonates provide 4,5-dihydro-3H-pyrroles. ..
  7. Too P, Chan G, Tnay Y, Hirao H, Chiba S. Hydride Reduction by a Sodium Hydride-Iodide Composite. Angew Chem Int Ed Engl. 2016;55:3719-23 pubmed publisher
    ..This remarkably simple protocol endows NaH with unprecedented and unique hydride-donor chemical reactivity. ..
  8. Tejo C, Pang J, Ong D, Oi M, Uchiyama M, Takita R, et al. Dearylation of arylphosphine oxides using a sodium hydride-iodide composite. Chem Commun (Camb). 2018;54:1782-1785 pubmed publisher
    ..The transient sodium phosphinite could be functionalized with a range of electrophiles in a one-pot fashion. ..