Alex T H Sia

Summary

Affiliation: KK Women's and Children's Hospital
Country: Singapore

Publications

  1. ncbi request reprint Automated intermittent epidural boluses improve analgesia induced by intrathecal fentanyl during labour
    Sebastian M H Chua
    Department of Anaesthesia, Singapore General Hospital, Singapore
    Can J Anaesth 51:581-5. 2004
  2. pmc Ethnicity and OPRM variant independently predict pain perception and patient-controlled analgesia usage for post-operative pain
    Ene Choo Tan
    KK Research Centre, KK Women s and Children s Hospital, Singapore
    Mol Pain 5:32. 2009
  3. doi request reprint The ongoing challenges of regional and general anaesthesia in obstetrics
    Alex T H Sia
    Department of Anaesthesia, KK Women s and Children s Hospital, Singapore
    Best Pract Res Clin Obstet Gynaecol 24:303-12. 2010
  4. ncbi request reprint The influence of ATP-binding cassette sub-family B member -1 (ABCB1) genetic polymorphisms on acute and chronic pain after intrathecal morphine for caesarean section: a prospective cohort study
    A T Sia
    KK Research Centre, Department of Women s Anaesthesia, KK Women s and Children s Hospital, Singapore
    Int J Obstet Anesth 19:254-60. 2010
  5. ncbi request reprint A118G single nucleotide polymorphism of human mu-opioid receptor gene influences pain perception and patient-controlled intravenous morphine consumption after intrathecal morphine for postcesarean analgesia
    Alex T Sia
    Department of Women s Anaesthesia, KK Women s and Children s Hospital, 100 Bukit Timah Road, Singapore
    Anesthesiology 109:520-6. 2008
  6. ncbi request reprint A randomized comparison of low doses of hyperbaric bupivacaine in combined spinal-epidural anesthesia for cesarean delivery
    Serene Leo
    Department of Women s Anaesthesia, Kandang Kerbau Women s and Children s Hospital, Singapore
    Anesth Analg 109:1600-5. 2009
  7. ncbi request reprint 0.2% Ropivacaine and levobupivacaine provide equally effective epidural labour analgesia
    Mia Supandji
    Department of Anesthesia O and G, KK Women and Children Hospital, 100 Bukit Timah Road, Singapore
    Can J Anaesth 51:918-22. 2004
  8. ncbi request reprint Hyperbaric bupivacaine 2.5 mg prolongs analgesia compared with plain bupivacaine when added to intrathecal fentanyl 25 microg in advanced labor
    Wendy H L Teoh
    Department of Anesthesia, KK Women s and Children s Hospital, Singapore
    Anesth Analg 97:873-7. 2003
  9. doi request reprint Failure of augmentation of labor epidural analgesia for intrapartum cesarean delivery: a retrospective review
    Shuying Lee
    Department of Women s Anesthesia, KK Women s and Children s Hospital, Singapore, Republic of Singapore
    Anesth Analg 108:252-4. 2009
  10. ncbi request reprint Ethnic differences in pain perception and patient-controlled analgesia usage for postoperative pain
    Ene Choo Tan
    KK Research Centre, KK Women s and Children s Hospital, and the Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Pain 9:849-55. 2008

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Automated intermittent epidural boluses improve analgesia induced by intrathecal fentanyl during labour
    Sebastian M H Chua
    Department of Anaesthesia, Singapore General Hospital, Singapore
    Can J Anaesth 51:581-5. 2004
    ..We compared the efficacy of epidural continual intermittent boluses (CIB) with a continuous epidural infusion (CEI) in prolonging labour analgesia induced by the combined spinal epidural (CSE) technique...
  2. pmc Ethnicity and OPRM variant independently predict pain perception and patient-controlled analgesia usage for post-operative pain
    Ene Choo Tan
    KK Research Centre, KK Women s and Children s Hospital, Singapore
    Mol Pain 5:32. 2009
    ....
  3. doi request reprint The ongoing challenges of regional and general anaesthesia in obstetrics
    Alex T H Sia
    Department of Anaesthesia, KK Women s and Children s Hospital, Singapore
    Best Pract Res Clin Obstet Gynaecol 24:303-12. 2010
    ..The need for involvement of a multidisciplinary team, good communication and challenges surrounding the provision of anaesthesia to such patients are discussed...
  4. ncbi request reprint The influence of ATP-binding cassette sub-family B member -1 (ABCB1) genetic polymorphisms on acute and chronic pain after intrathecal morphine for caesarean section: a prospective cohort study
    A T Sia
    KK Research Centre, Department of Women s Anaesthesia, KK Women s and Children s Hospital, Singapore
    Int J Obstet Anesth 19:254-60. 2010
    ..We investigated the effect of ABCB1 gene polymorphisms on analgesia and the development of persistent pain in post caesarean patients...
  5. ncbi request reprint A118G single nucleotide polymorphism of human mu-opioid receptor gene influences pain perception and patient-controlled intravenous morphine consumption after intrathecal morphine for postcesarean analgesia
    Alex T Sia
    Department of Women s Anaesthesia, KK Women s and Children s Hospital, 100 Bukit Timah Road, Singapore
    Anesthesiology 109:520-6. 2008
    ..The purpose of this study was to investigate whether this polymorphism contributes to the variability in response to morphine for postcesarean analgesia...
  6. ncbi request reprint A randomized comparison of low doses of hyperbaric bupivacaine in combined spinal-epidural anesthesia for cesarean delivery
    Serene Leo
    Department of Women s Anaesthesia, Kandang Kerbau Women s and Children s Hospital, Singapore
    Anesth Analg 109:1600-5. 2009
    ....
  7. ncbi request reprint 0.2% Ropivacaine and levobupivacaine provide equally effective epidural labour analgesia
    Mia Supandji
    Department of Anesthesia O and G, KK Women and Children Hospital, 100 Bukit Timah Road, Singapore
    Can J Anaesth 51:918-22. 2004
    ..To compare the duration of epidural analgesia induced by levobupivacaine and ropivacaine at clinically relevant doses...
  8. ncbi request reprint Hyperbaric bupivacaine 2.5 mg prolongs analgesia compared with plain bupivacaine when added to intrathecal fentanyl 25 microg in advanced labor
    Wendy H L Teoh
    Department of Anesthesia, KK Women s and Children s Hospital, Singapore
    Anesth Analg 97:873-7. 2003
    ..05). The side-effect profile was similar. Under these circumstances, hyperbaric bupivacaine conferred an increased duration of IT analgesia compared with plain bupivacaine...
  9. doi request reprint Failure of augmentation of labor epidural analgesia for intrapartum cesarean delivery: a retrospective review
    Shuying Lee
    Department of Women s Anesthesia, KK Women s and Children s Hospital, Singapore, Republic of Singapore
    Anesth Analg 108:252-4. 2009
    ..001), >or=2 episodes of breakthrough pain during labor (P < 0.001) and prolonged duration of neuraxial labor analgesia (P = 0.02)...
  10. ncbi request reprint Ethnic differences in pain perception and patient-controlled analgesia usage for postoperative pain
    Ene Choo Tan
    KK Research Centre, KK Women s and Children s Hospital, and the Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Pain 9:849-55. 2008
    ..The ethnic differences in pain score and morphine self-administration persisted after controlling for age, body mass index, and duration of operation...
  11. ncbi request reprint Combined spinal epidural analgesia for labor with and without 3 ml of 1.5% epidural lidocaine
    Yvonne Lim
    Department of Anesthesia, KK Women s and Children s Hospital, Singapore, Singapore
    Med Sci Monit 13:CR9-13. 2007
    ..5% lidocaine injected immediately after the initiation of combined spinal epidural analgesia and followed by a continuous epidural infusion would prolong the duration of analgesia and decrease the incidence of breakthrough pain...
  12. ncbi request reprint Comparison of intrathecal levobupivacaine with and without fentanyl in combined spinal epidural for labor analgesia
    Yvonne Lim
    Department of Anesthesia O and G, KK Women s and Children s Hospital, Singapore, Singapore
    Med Sci Monit 10:PI87-91. 2004
    ..We wished to determine if addition of IT fentanyl to IT levobupivacaine in combined spinal epidural (CSE) could prolong obstetric analgesia when epidural infusion is initiated promptly...
  13. doi request reprint Colloid preload versus coload for spinal anesthesia for cesarean delivery: the effects on maternal cardiac output
    Wendy H L Teoh
    Department of Women s Anesthesia, KK Women s and Children s Hospital, Singapore
    Anesth Analg 108:1592-8. 2009
    ..4 [Voluven 6%]) and an identical coload on maternal CO and the incidence of hypotension after spinal anesthesia for cesarean delivery. Secondary outcomes studied were neonatal acid- base status and predelivery vasopressor requirements...
  14. ncbi request reprint A comparison of median effective doses of intrathecal levobupivacaine and ropivacaine for labor analgesia
    Alex T Sia
    Department of Anesthesia, KK Women s and Children s Hospital, Singapore
    Anesthesiology 102:651-6. 2005
    ..The study was designed to determine and compare the median effective doses (MEDs) of intrathecal ropivacaine with levobupivacaine for labor analgesia...
  15. ncbi request reprint A comparison of a basal infusion with automated mandatory boluses in parturient-controlled epidural analgesia during labor
    Alex T Sia
    Department of Women s Anaesthesia, KK Women s and Children s Hospital, Singapore
    Anesth Analg 104:673-8. 2007
    ..We hypothesized that epidural local anesthetic consumption would be lower if basal intermittent boluses were used instead of a basal infusion...
  16. ncbi request reprint Addition of bupivacaine 1.25 mg to fentanyl confers no advantage over fentanyl alone for intrathecal analgesia in early labour
    Evangeline H L Lim
    Department of Anaesthesia, KK Women s and Children s Hospital, Singapore
    Can J Anaesth 49:57-61. 2002
    ..25 mg of bupivacaine to intrathecal fentanyl on the duration of analgesia in an Asian population and b) to examine if the baricity of the local anesthetic at this dose has any bearing on the duration and quality of block...
  17. doi request reprint A randomised trial of the analgesic efficacy of ultrasound-guided transversus abdominis plane block after caesarean delivery under general anaesthesia
    Terry T Tan
    Coombe Women and Infants University Hospital, Dublin, Ireland
    Eur J Anaesthesiol 29:88-94. 2012
    ..Previous studies examining the efficacy of transversus abdominis plane block after caesarean section have mostly been in parturients under spinal anaesthesia...
  18. ncbi request reprint Combined spinal epidural does not cause a higher sensory block than single shot spinal technique for cesarean delivery in laboring women
    Yvonne Lim
    Department of Women s Anesthesia, KK Women s and Children s Hospital, 100 Bukit Timah Road, Singapore 229899
    Anesth Analg 103:1540-2. 2006
    ..We tested whether this is true also in laboring women who may have variable epidural pressures...
  19. ncbi request reprint Combined spinal epidural causes higher level of block than equivalent single-shot spinal anesthesia in elective cesarean patients
    Farida Ithnin
    Department of Women s Anesthesia, KK Women s and Children s Hospital, Singapore
    Anesth Analg 102:577-80. 2006
    ....
  20. ncbi request reprint A comparison of duration of analgesia of intrathecal 2.5 mg of bupivacaine, ropivacaine, and levobupivacaine in combined spinal epidural analgesia for patients in labor
    Yvonne Lim
    Department of Anesthesia, KK Women s and Children s Hospital, 100 Bukit Timah Road, Singapore 229899, Republic of Singapore
    Anesth Analg 98:235-9, table of contents. 2004
    ..05). The profile of the other side effects was indistinguishable between the groups. With the current regimen, IT bupivacaine produced the longest duration of labor analgesia...