Kong Boo Phua

Summary

Affiliation: KK Women's and Children's Hospital
Country: Singapore

Publications

  1. pmc Incidence of intussusception in Singaporean children aged less than 2 years: a hospital-based prospective study
    Kong Boo Phua
    KK Women s and Children s Hospital, Singapore, Singapore
    BMC Pediatr 13:161. 2013
  2. doi request reprint Rotavirus vaccine RIX4414 efficacy sustained during the third year of life: a randomized clinical trial in an Asian population
    Kong Boo Phua
    Department of Paediatrics, KK Women s and Children s Hospital, Singapore 229899, Singapore
    Vaccine 30:4552-7. 2012
  3. ncbi request reprint Immunogenicity, reactogenicity and safety of a diphtheria-tetanus-acellular pertussis-inactivated polio and Haemophilus influenzae type b vaccine in a placebo-controlled rotavirus vaccine study
    Kong Boo Phua
    Department of Paediatrics, KK Women s and Children s Hospital, National University Hospital, Singapore
    Ann Acad Med Singapore 37:546-53. 2008
  4. doi request reprint Safety and efficacy of human rotavirus vaccine during the first 2 years of life in Asian infants: randomised, double-blind, controlled study
    K B Phua
    Department of Paediatrics, KK Women s and Children s Hospital, 100 Bukit, Timah Road, Singapore 229899, Singapore
    Vaccine 27:5936-41. 2009
  5. ncbi request reprint Evaluation of RIX4414, a live, attenuated rotavirus vaccine, in a randomized, double-blind, placebo-controlled phase 2 trial involving 2464 Singaporean infants
    Kong Boo Phua
    Department of Medicine, KK Women s and Children s Hospital, Singapore
    J Infect Dis 192:S6-S16. 2005
  6. ncbi request reprint An update of paediatric intussusception incidence in Singapore: 1997-2007, 11 years of intussusception surveillance
    Nancy Tan
    Department of Paediatrics, KK Women s and Children s Hospital, Singapore
    Ann Acad Med Singapore 38:690-2. 2009
  7. doi request reprint A hospital-based surveillance of rotavirus gastroenteritis in children <5 years of age in Singapore
    Kong Boo Phua
    From the Departments of Pediatrics and Pathology and Laboratory Medicine, KK Women s and Children s Hospital, Singapore GlaxoSmithKline Pharmaceuticals Pvt Ltd, India Emergent BioSolutions and GlaxoSmithKline Vaccines Pvt Ltd, Singapore
    Pediatr Infect Dis J 32:e426-31. 2013

Collaborators

Detail Information

Publications7

  1. pmc Incidence of intussusception in Singaporean children aged less than 2 years: a hospital-based prospective study
    Kong Boo Phua
    KK Women s and Children s Hospital, Singapore, Singapore
    BMC Pediatr 13:161. 2013
    ..Continuous surveillance for intussusception (IS) is important for monitoring the safety of second-generation rotavirus vaccines. The present study aimed to assess the incidence of IS in Singaporean children aged < 2 years...
  2. doi request reprint Rotavirus vaccine RIX4414 efficacy sustained during the third year of life: a randomized clinical trial in an Asian population
    Kong Boo Phua
    Department of Paediatrics, KK Women s and Children s Hospital, Singapore 229899, Singapore
    Vaccine 30:4552-7. 2012
    ..0% [84.8-100]) and pooled non-G1 RV types (94.9% [80.2-99.4]). This study shows that the vaccine is highly efficacious, regardless of circulating RV-types, up to the first 3 years of life in affluent Asian urban populations...
  3. ncbi request reprint Immunogenicity, reactogenicity and safety of a diphtheria-tetanus-acellular pertussis-inactivated polio and Haemophilus influenzae type b vaccine in a placebo-controlled rotavirus vaccine study
    Kong Boo Phua
    Department of Paediatrics, KK Women s and Children s Hospital, National University Hospital, Singapore
    Ann Acad Med Singapore 37:546-53. 2008
    ..This phase-II study (Rota-007) evaluated the immunogenicity, reactogenicity and safety of a DTPa-IPV/Hib combined vaccine when co-administered with a rotavirus vaccine...
  4. doi request reprint Safety and efficacy of human rotavirus vaccine during the first 2 years of life in Asian infants: randomised, double-blind, controlled study
    K B Phua
    Department of Paediatrics, KK Women s and Children s Hospital, 100 Bukit, Timah Road, Singapore 229899, Singapore
    Vaccine 27:5936-41. 2009
    ..No intussusception cases were reported within 31 days post-vaccination. RIX4414 shows a good safety profile and offers high protection during the first 2 years of life with potentially significant public health impact in this population...
  5. ncbi request reprint Evaluation of RIX4414, a live, attenuated rotavirus vaccine, in a randomized, double-blind, placebo-controlled phase 2 trial involving 2464 Singaporean infants
    Kong Boo Phua
    Department of Medicine, KK Women s and Children s Hospital, Singapore
    J Infect Dis 192:S6-S16. 2005
    ..Hence, a live, attenuated monovalent vaccine was developed with human strain RIX4414 (G1P1A P[8] specificity). Vaccination trials involving infants are ongoing in developed and developing countries...
  6. ncbi request reprint An update of paediatric intussusception incidence in Singapore: 1997-2007, 11 years of intussusception surveillance
    Nancy Tan
    Department of Paediatrics, KK Women s and Children s Hospital, Singapore
    Ann Acad Med Singapore 38:690-2. 2009
    ..This paper presents IS surveillance data from Singapore between 1997 and 2007, including the period between November 2005 and December 2007 when rotavirus vaccines (primarily Rotarix) were available to newborns in Singapore...
  7. doi request reprint A hospital-based surveillance of rotavirus gastroenteritis in children <5 years of age in Singapore
    Kong Boo Phua
    From the Departments of Pediatrics and Pathology and Laboratory Medicine, KK Women s and Children s Hospital, Singapore GlaxoSmithKline Pharmaceuticals Pvt Ltd, India Emergent BioSolutions and GlaxoSmithKline Vaccines Pvt Ltd, Singapore
    Pediatr Infect Dis J 32:e426-31. 2013
    ..These vaccines are optional and are not included in the National Childhood Immunization Program. This study aimed to determine the incidence of rotavirus gastroenteritis-associated hospitalizations among children <5 years of age...