Ralf Jauch

Summary

Country: Singapore

Publications

  1. Jauch R, Ng C, Saikatendu K, Stevens R, Kolatkar P. Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog. J Mol Biol. 2008;376:758-70 pubmed publisher
    ..Together, the structural and functional evidence establish Nanog as a distant member of a Q50-type HD despite having considerable variation at the sequence level. ..
  2. Jauch R, Choo S, Ng C, Kolatkar P. Crystal structure of the dimeric Oct6 (POU3f1) POU domain bound to palindromic MORE DNA. Proteins. 2011;79:674-7 pubmed publisher
  3. Jauch R, Ng C, Narasimhan K, Kolatkar P. The crystal structure of the Sox4 HMG domain-DNA complex suggests a mechanism for positional interdependence in DNA recognition. Biochem J. 2012;443:39-47 pubmed publisher
    ..These analyses underline the complexity of the DNA recognition by TFs and provide an experimental validation for the conceptual framework of positional interdependence and secondary binding motifs. ..