Research Topics
| A L MunnSummaryAffiliation: Institute of Molecular Agrobiology Country: Singapore Publications
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Detail Information
Publications
The yeast endocytic membrane transport systemA L Munn
Laboratory of Yeast Cell Biology, Institute of Molecular Agrobiology, National University of Singapore, Singapore, 117604, Republic of Singapore
Microsc Res Tech 51:547-62. 2000..The visualization of the S. cerevisiae endocytic pathway has revealed similarities to endocytic pathways visualized in higher eukaryotes...
Molecular requirements for the internalisation step of endocytosis: insights from yeastA L Munn
Laboratory of Yeast Cell Biology, Institute of Molecular Agrobiology, 1 Research Link, National University of Singapore, 117604, Singapore
Biochim Biophys Acta 1535:236-57. 2001..This discovery suggests models whereby endocytic vesicles may be actively pushed from the plasma membrane and into the cell by newly forming and rapidly extending actin filaments...
Vrp1p functions in both actomyosin ring-dependent and Hof1p-dependent pathways of cytokinesisS N Naqvi
Laboratory of Yeast Cell Biology, Institute of Molecular Agrobiology, 1 Research Link, The National University of Singapore, Singapore 117604, Republic of Singapore
Traffic 2:189-201. 2001..Vrp1p thus acts in both actomyosin ring formation and function, as well as in Hof1p localisation during cytokinesis...
Functions of Vrp1p in cytokinesis and actin patches are distinct and neither requires a WH2/V domainT Thanabalu
Institute of Molecular Agrobiology, 1 Research Link, The National University of Singapore, Singapore 117604, Republic of Singapore
EMBO J 20:6979-89. 2001..The functions of Vrp1 in viability at 37 degrees C and cytokinesis do not require efficient localization to, and function in, the cortical actin cytoskeleton...
The WASp homologue Las17p functions with the WIP homologue End5p/verprolin and is essential for endocytosis in yeastS N Naqvi
Institute of Molecular Agrobiology, National University of Singapore, Republic of Singapore
Curr Biol 8:959-62. 1998..As las17 delta deletion mutants are blocked in endocytosis, we conclude that Las17p and End5p interact and are essential for endocytosis...
End13p/Vps4p is required for efficient transport from early to late endosomes in Saccharomyces cerevisiaeR Zahn
Institute of Molecular Agrobiology, National University of Singapore, Singapore, Republic of Singapore
J Cell Sci 114:1935-47. 2001..Our results indicate that End13p/Vps4p may play an important role in multiple steps of membrane traffic through the endocytic pathway...
End4p/Sla2p interacts with actin-associated proteins for endocytosis in Saccharomyces cerevisiaeA Wesp
Biozentrum, University of Basel, Switzerland
Mol Biol Cell 8:2291-306. 1997..Combined biochemical, functional, and genetic analysis lead us to propose that End4p may mediate endocytosis through interaction with other actin-associated proteins, perhaps Rvs167p, a protein essential for endocytosis...
end5, end6, and end7: mutations that cause actin delocalization and block the internalization step of endocytosis in Saccharomyces cerevisiaeA L Munn
Department of Biochemistry, Biozentrum of the University of Basel, Switzerland
Mol Biol Cell 6:1721-42. 1995..We propose that Vrp1p, Rvs161p, and Rvs167p are components of a cytoskeletal structure that contains actin and fimbrin and that is required for formation of endocytic vesicles at the plasma membrane...
Endocytosis is required for the growth of vacuolar H(+)-ATPase-defective yeast: identification of six new END genesA L Munn
Department of Biochemistry, Biozentrum of the University of Basel, Switzerland
J Cell Biol 127:373-86. 1994..The mutations that result in a defect in alpha-factor uptake are not allelic to any of the genes previously shown to encode endocytic functions...
Specific sterols required for the internalization step of endocytosis in yeastA L Munn
Biozentrum of the University of Basel, CH 4056 Basel, Switzerland
Mol Biol Cell 10:3943-57. 1999..A single desaturation at C-8,9 was not sufficient to support internalization at 37 degrees C whereas two double bonds, either at C-5,6 and C-7,8 or at C-5,6 and C-8,9, allowed internalization...
