D X Liu

Summary

Affiliation: Institute of Molecular Agrobiology
Country: Singapore

Publications

  1. ncbi Proteolytic mapping of the coronavirus infectious bronchitis virus 1b polyprotein: evidence for the presence of four cleavage sites of the 3C-like proteinase and identification of two novel cleavage products
    D X Liu
    Institute of Molecular Agrobiology, National University of Singapore, Singapore
    Virology 246:288-97. 1998
  2. pmc Induction of caspase-dependent apoptosis in cultured cells by the avian coronavirus infectious bronchitis virus
    C Liu
    Institute of Molecular Agrobiology, 1 Research Link, The National University of Singapore, Singapore 117406, Singapore
    J Virol 75:6402-9. 2001
  3. pmc Proteolytic processing of the coronavirus infectious bronchitis virus 1a polyprotein: identification of a 10-kilodalton polypeptide and determination of its cleavage sites
    D X Liu
    Institute of Molecular Agrobiology, National University of Singapore
    J Virol 71:1814-20. 1997
  4. ncbi Further identification and characterization of novel intermediate and mature cleavage products released from the ORF 1b region of the avian coronavirus infectious bronchitis virus 1a/1b polyprotein
    H Y Xu
    Institute of Molecular Agrobiology, 1 Research Link, The National University of Singapore, Singapore 117604
    Virology 288:212-22. 2001
  5. ncbi The missing link in coronavirus assembly. Retention of the avian coronavirus infectious bronchitis virus envelope protein in the pre-Golgi compartments and physical interaction between the envelope and membrane proteins
    K P Lim
    Institute of Molecular Agrobiology, The National University of Singapore, 1 Research Link, Singapore 117604
    J Biol Chem 276:17515-23. 2001
  6. ncbi Emergence of a coronavirus infectious bronchitis virus mutant with a truncated 3b gene: functional characterization of the 3b protein in pathogenesis and replication
    S Shen
    Institute of Molecular and Cell Biology, National University of Singapore, 117604, Singapore
    Virology 311:16-27. 2003
  7. pmc Membrane association and dimerization of a cysteine-rich, 16-kilodalton polypeptide released from the C-terminal region of the coronavirus infectious bronchitis virus 1a polyprotein
    Lisa F P Ng
    Institute of Molecular Agrobiology, The National University of Singapore, Singapore 117604
    J Virol 76:6257-67. 2002
  8. ncbi Comparison of the 5' leader sequences of North American isolates of reference and field strains of porcine reproductive and respiratory syndrome virus (PRRSV)
    C Tan
    Institute of Molecular Agrobiology, National University of Singapore, Singapore
    Virus Genes 22:209-17. 2001
  9. ncbi Coronavirus envelope protein: a small membrane protein with multiple functions
    D X Liu
    Institute of Molecular and Cell Biology, 61 Biopolis Drive, Proteos, Singapore, 138673, Singapore
    Cell Mol Life Sci 64:2043-8. 2007
  10. ncbi Translation initiation at an upstream CUG codon regulates the expression of Hibiscus chlorotic ringspot virus coat protein
    Dora Chin Yen Koh
    Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore 117543, Singapore
    Virus Res 122:35-44. 2006

Collaborators

  • J Kwang
  • C Liu
  • L Chang
  • S Shen
  • K P Lim
  • Dora Chin Yen Koh
  • Lisa F P Ng
  • C Tan
  • H Y Xu
  • Xiaoxing Wang
  • Sek Man Wong
  • Z L Wen

Detail Information

Publications10

  1. ncbi Proteolytic mapping of the coronavirus infectious bronchitis virus 1b polyprotein: evidence for the presence of four cleavage sites of the 3C-like proteinase and identification of two novel cleavage products
    D X Liu
    Institute of Molecular Agrobiology, National University of Singapore, Singapore
    Virology 246:288-97. 1998
    ..Taken together with the 100-kDa protein previously identified, these results suggest that the ORF 1b region of IBV mRNA1 may be able to encode five mature products...
  2. pmc Induction of caspase-dependent apoptosis in cultured cells by the avian coronavirus infectious bronchitis virus
    C Liu
    Institute of Molecular Agrobiology, 1 Research Link, The National University of Singapore, Singapore 117406, Singapore
    J Virol 75:6402-9. 2001
    ..This study adds one more example to the growing list of animal viruses that induce apoptosis during their replication cycles...
  3. pmc Proteolytic processing of the coronavirus infectious bronchitis virus 1a polyprotein: identification of a 10-kilodalton polypeptide and determination of its cleavage sites
    D X Liu
    Institute of Molecular Agrobiology, National University of Singapore
    J Virol 71:1814-20. 1997
    ....
  4. ncbi Further identification and characterization of novel intermediate and mature cleavage products released from the ORF 1b region of the avian coronavirus infectious bronchitis virus 1a/1b polyprotein
    H Y Xu
    Institute of Molecular Agrobiology, 1 Research Link, The National University of Singapore, Singapore 117604
    Virology 288:212-22. 2001
    ....
  5. ncbi The missing link in coronavirus assembly. Retention of the avian coronavirus infectious bronchitis virus envelope protein in the pre-Golgi compartments and physical interaction between the envelope and membrane proteins
    K P Lim
    Institute of Molecular Agrobiology, The National University of Singapore, 1 Research Link, Singapore 117604
    J Biol Chem 276:17515-23. 2001
    ....
  6. ncbi Emergence of a coronavirus infectious bronchitis virus mutant with a truncated 3b gene: functional characterization of the 3b protein in pathogenesis and replication
    S Shen
    Institute of Molecular and Cell Biology, National University of Singapore, 117604, Singapore
    Virology 311:16-27. 2003
    ..These results suggest that the 3b gene product is not essential for the replication of IBV...
  7. pmc Membrane association and dimerization of a cysteine-rich, 16-kilodalton polypeptide released from the C-terminal region of the coronavirus infectious bronchitis virus 1a polyprotein
    Lisa F P Ng
    Institute of Molecular Agrobiology, The National University of Singapore, Singapore 117604
    J Virol 76:6257-67. 2002
    ..Furthermore, increased accumulation of the 16-kDa protein upon stimulation with epidermal growth factor was observed, providing preliminary evidence that the protein might be involved in the growth factor signaling pathway...
  8. ncbi Comparison of the 5' leader sequences of North American isolates of reference and field strains of porcine reproductive and respiratory syndrome virus (PRRSV)
    C Tan
    Institute of Molecular Agrobiology, National University of Singapore, Singapore
    Virus Genes 22:209-17. 2001
    ....
  9. ncbi Coronavirus envelope protein: a small membrane protein with multiple functions
    D X Liu
    Institute of Molecular and Cell Biology, 61 Biopolis Drive, Proteos, Singapore, 138673, Singapore
    Cell Mol Life Sci 64:2043-8. 2007
    ..Here we review recent progress in characterization of the biochemical properties, membrane topology and functions of the protein...
  10. ncbi Translation initiation at an upstream CUG codon regulates the expression of Hibiscus chlorotic ringspot virus coat protein
    Dora Chin Yen Koh
    Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore 117543, Singapore
    Virus Res 122:35-44. 2006
    ..In addition, a previously identified internal ribosome entry site was shown to control the expression of p27 and p38 in the subgenomic RNA 2...