Siow Ann Chong

..To examine the association between mental disorders and work disability in the adult resident population in Singapore...

..Incorporation of mental health education and screening of mental disorders in the workforce should also be augmented with work practices that protect against discriminating those with mental disorders...

..The problem of wide treatment gaps in mental disorders is endemic world wide. The study aims to establish the treatment gap of common mental disorders in Singapore...

..This study aims to examine the pattern of services utilisation and the factors associated with help-seeking behaviour among those with mental disorders in the multi-ethnic Asian population of Singapore...

..This study aims to assess the prevalence rates of mental disorders and chronic medical conditions in the Singapore resident population, and examine their association and respective impact on the quality of life...

..The aim of this study was to establish the prevalence of select mental disorders and their associated sociodemographic correlates in the adult Singapore resident population...

..This essay examines these factors and how the melding of that could lead to breakthrough discoveries. It may in some instances, go wrong, or take a morally ambiguous path...

..We do not purport to offer a blueprint for the future; we do, however, seek to advance the debate by identifying some of the key questions to which better answers are required...

..To describe the establishment and development of an Early Psychosis Intervention Programme in Singapore that is based on a business model and with concepts drawn from the corporate world...

..In this study, we established the Duration of Psychosis (DUP) in a sample of patients with first-episode psychosis and examined the pathways to care...

..The purpose of this study was to establish rates of spontaneous parkinsonism (SP) among the different types of psychosis. We hypothesized that the rate would be higher among persons with affective symptoms...

..This study was conducted to examine the impact of early detection strategies of an early psychosis intervention programme on the duration of untreated psychosis (DUP) and the pattern of help-seeking behaviour...

..Caution should be exercised and monitoring with ECG should be considered in patients prescribed chlorpromazine and depot antipsychotic medications even at recommended doses...

....

..PPA administration with educational module supplementation may provide a valuable addition to clinical trial procedures in patients with schizophrenia...

..This study assessed public perceptions and attitudes towards and causal beliefs about mental health problems in Singapore - a multi-racial country in South-East Asia...

..This paper describes the rationale, aims and development of the Singapore Translational and Clinical Research in Psychosis, which is a 5-year programme...

..This paper describes the process of choosing the relevant measures with the appropriate attributes, and suggests a framework, which can serve as a guide for selecting mental health performance measures...

..This study evaluated the quality of care in an early psychosis intervention programme (EPIP), as compared to standard treatment received by patients prior to the inception of the programme...

..However, prospective long-term studies with multiple assessment points are needed to clarify the role of glucose metabolism in the development of tardive dyskinesia...

..In this case the patient was very distressed by his symptoms and had requested treatment with medications. Indeed, treatment has resulted in the remission of his symptoms and restored him to his previous level of functioning...

..The association of TD with the serine/serine genotype of the DRD3 may be an epiphenomenon of patients with a subtype of schizophrenia who had more exposure to neuroleptics...

....

..0 to establish lifetime and 12-month prevalence of mental disorders, the current use of mental health services (both Western and traditional services), the treatment gaps and loss of role functioning...

..However, it is not clear as to how academic performance compares as a marker for other mental disorders. The objective of this study was to examine whether educational attainment is a candidate marker for certain psychiatric disorders...

..This study is unusual in that it involved almost the entire male population in 1 year but its relevance is the development of a screening instrument that can be used with ease in a large population of conscripts...

....

..This study was undertaken with the aim to identify the prevalence and patterns of substance abuse among patients with first-episode schizophrenia in the city-state of Singapore...

..The objective of this study was to examine the extent of health care utilisation (excluding costs) of diabetic patients with and without depressive symptoms attending a specialist clinic in Singapore...

..The aim of this study was to investigate four biallelic polymorphisms in the tumor necrosis factor-alpha (TNFalpha) gene promoter in relation to susceptibility to schizophrenia...

..We hypothesized that ARVCF gene haplotypes influence caudate nucleus volume, fractional anisotropy, and neurocognitive functioning in schizophrenia...

..We studied the association of psychotic symptoms with educational attainment and other psychiatric disorders in 23,248 male pre-enlistees for National Service in Singapore...

....

..To establish the prevalence, correlates, comorbidity and treatment gap of alcohol use disorders in the Singapore resident population...

..To evaluate the diagnostic stability of psychotic disorders over a 2 year period in patients presenting with first-episode psychosis...

..The findings suggest distributed involvement of cortical and subcortical regions underlying passivity and support the notion of neural network models underlying specific psychiatric symptoms such as passivity...

..Diabetes mellitus (DM) is a serious chronic illness that has a major impact on the quality of life of the individuals. Our aim was to examine the determinants of health-related quality of life (HRQOL) in patients with DM...

..The aims of this study were to examine the prevalence and severity of aggression in patients with first-episode psychosis and to identify the association between aggression and sociodemographic and clinical factors...

..The aims of the current study were to elucidate the association between body mass index (BMI) and mental disorders and to examine whether these associations are moderated by socio-demographic correlates and comorbid physical disorders...

..Singapore has one of the world's highest rates of diabetes mellitus (DM). DM is also associated with depression, the nature of this relation is possibly bidirectional and complex and there are a number of putative associated factors...

....

..This study seeks to evaluate the health-related QOL in patients with first episode psychosis and comparing those with psychiatric comorbidity to those without in an Early Psychosis Intervention Program...

..The project will collect both observational and clinically relevant data from an at-risk group: adolescents and young adults...

..We present the item reduction and validation of the Positive Mental Health (PMH) instrument in a community-based adult sample in Singapore...

..90; 95% confidence interval, 1.12-3.20; P = 0.017). Our finding showed a robust association with increased mortality rate and TD, but we failed to find any significant association with any specific cause of death and TD...

..To validate the CRAFFT screening test, against the DSM IV Axis 1-based diagnostic inventory in a population of adolescents and young adult males in Singapore...

..This study aimed to establish the prevalence of diabetes mellitus (DM) and impaired glucose tolerance in patients with schizophrenia and to elucidate some of the factors associated with hyperglycemia...

..Existing instruments are developed in Western societies that differ in their conceptualization of well-being from Asian populations. Moreover, very few instruments address the multidimensional construct of well-being...

..We investigate the predictors of perceived burden of care among relatives of people with any chronic physical or mental illness using secondary data from a nationwide survey in Singapore...

..To study the patterns of readmission in Singapore using a cohort of first admission schizophrenia patients to the state mental health institute...

..Our results suggest that smaller hippocampal volumes are present even in early stages of the illness...

..The aim of the current study was to establish and compare the QALY losses associated with select mental and chronic physical conditions in Singapore...

....

..This study was conducted to provide evidence of the reliability and construct validity of the MSPSS in an adult Asian population with schizophrenia...

..However, there remain various challenges which we are yet to overcome...

..The impact is more pronounced when early onset is also associated with treatment delay. Little is known about the age of onset (AOO) for mental disorders and its predictors in Singapore...

..Reports of rates of depression among different Asian ethnic groups within the same country using standardized assessments are rare in the extant literature...

....

..This study aimed to establish the prevalence of command hallucinations and to identify the factors that affect compliance with the commands, together with patients' coping methods...

..To establish if there is an association between cigarette smoking and tardive dyskinesia (TD) in patients with schizophrenia and to evaluate the role of the CYP1A2 polymorphism in TD in patients of Chinese descent...

..To establish if there are ethnic differences in the various metabolic disturbances that are common with clozapine treatment...

..We tested the hypothesis that patients with first-episode schizoaffective disorder had better clinical and functional outcomes compared to patients with first-episode schizophrenia...

..LAR was effective in improving symptom severity within the first month of starting treatment. However, significant increases in weight and plasma levels of fasting glucose and cholesterol raise concern about metabolic side effects...

..Patients with dyskinetic movements at baseline could have a more treatment refractory course of illness...

..This article seeks to provide an overview on what our group has embarked on--to elucidate genetic risk factors for schizophrenia within the Chinese ethnic group...

..We studied the prevalence of akathisia and its relationship to a number of sociodemographic and clinical factors in a population of Chinese inpatients with Schizophrenia...

..We also hypothesize that raised thyroid hormones are associated with more severe psychopathology...

..To determine the prevalence rates of psychiatric comorbidity in a hospitalized Asian patient group with first episode psychosis and examine its clinical correlates...

..To evaluate the effect of risperidone treatment on the cognitive functioning in a group of Asian patients with schizophrenia..

..This study aims to examine the psychological impact of SARS on general practitioners (GPs) and traditional Chinese medicine (TCM) practitioners in Singapore...

..This study aims to examine the socio-demographic and clinical correlates of the duration of untreated psychosis (DUP) in first-episode psychosis patients in an Asian country...

....

..The study aimed to establish the prevalence of BPD and examine the associated socio-demographic correlates, comorbidity, severity, impairment and treatment contact in the Singapore resident population...

..These differences were consistent with findings from Caucasian population, and could possibly be explained by influences of oestrogen...

..The area under the curve indicated moderate discriminatory capabilities. Our results suggest that the PDQ-4+ could be used as a potential screening instrument for personality disorders in prison inmates...

..In particular, the assessment of decisional capacity and the role of the doctors (if the patient lacks capacity) are discussed. Recommendations are also made on how to better manage such situations...

..Alternative explanations are also possible, providing possible foci for psychological support and intervention...

..In this paper, we attempt to examine these putative psychosocial factors and place them in a temporal context and propose a neurobiological mechanism linking these factors...

..Longitudinal prospective studies will also be of added advantage for evaluation of prognostic utility of BDNF in schizophrenia...

..From our results, this 5-HTTLPR polymorphism is unlikely to have a major effect on suicidal behavior in Chinese patients with schizophrenia...

....