James H P Hui

Summary

Country: Singapore

Publications

  1. doi request reprint Cartilage repair: 2013 Asian update
    James H P Hui
    Cartilage Repair Program, Therapeutic Tissue Engineering Laboratory, Department of Orthopaedic Surgery, National University Health System, National University of Singapore, Singapore Electronic address
    Arthroscopy 29:1992-2000. 2013
  2. pmc Oligo[poly(ethylene glycol)fumarate] hydrogel enhances osteochondral repair in porcine femoral condyle defects
    James H Hui
    Cartilage Repair Program, Therapeutic Tissue Engineering Laboratory, Department of Orthopaedic Surgery, National University Health System, National University Hospital, Yong Loo Lin School of Medicine, National University of Singapore, 1E, Kent Ridge Road, Singapore, 119288, Singapore
    Clin Orthop Relat Res 471:1174-85. 2013
  3. doi request reprint Implantation of orthobiologic, biodegradable scaffolds in osteochondral repair
    James H P Hui
    Division of Paediatric Orthopaedics, National University Hospital, 5, Lower Kent Ridge Road, Kent Ridge Wing 2, Level 3, 119074, Singapore
    Orthop Clin North Am 43:255-61, vii. 2012
  4. pmc Improved mesenchymal stem cells attachment and in vitro cartilage tissue formation on chitosan-modified poly(L-lactide-co-epsilon-caprolactone) scaffold
    Zheng Yang
    Tissue Engineering Program, Life Sciences Institute, National University of Singapore, Singapore
    Tissue Eng Part A 18:242-51. 2012
  5. ncbi request reprint 11th Yahya Cohen Memorial Lecture: An in vivo comparative study of the ability of derived mesenchymal stem cells in the treatment of partial growth arrest
    James H P Hui
    Department of Orthopaedic Surgery, National University of Singapore, Singapore
    Ann Acad Med Singapore 38:84-7. 2009
  6. ncbi request reprint A comparison between the chondrogenic potential of human bone marrow stem cells (BMSCs) and adipose-derived stem cells (ADSCs) taken from the same donors
    Hassan Afizah
    Department of Orthopaedic Surgery, National University of Singapore, Singapore
    Tissue Eng 13:659-66. 2007
  7. ncbi request reprint Cartilaginous ECM component-modification of the micro-bead culture system for chondrogenic differentiation of mesenchymal stem cells
    Ying Nan Wu
    Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore NUS Tissue Engineering Program NUSTEP, National University Hospital, Lower Kent Ridge Road, Singapore 119074, Republic of Singapore
    Biomaterials 28:4056-67. 2007
  8. ncbi request reprint A novel, minimally-invasive technique of cartilage repair in the human knee using arthroscopic microfracture and injections of mesenchymal stem cells and hyaluronic acid--a prospective comparative study on safety and short-term efficacy
    Kevin B L Lee
    Department of Orthopaedic Surgery, National University Hospital, Singapore
    Ann Acad Med Singapore 41:511-7. 2012
  9. doi request reprint Injectable cultured bone marrow-derived mesenchymal stem cells in varus knees with cartilage defects undergoing high tibial osteotomy: a prospective, randomized controlled clinical trial with 2 years' follow-up
    Keng Lin Wong
    Department of Orthopaedic Surgery, University Orthopaedic, Hand and Reconstructive Microsurgery Cluster, National University Health System, Singapore
    Arthroscopy 29:2020-8. 2013
  10. ncbi request reprint An analysis of soft tissue allograft anterior cruciate ligament reconstruction in a rabbit model: a short-term study of the use of mesenchymal stem cells to enhance tendon osteointegration
    Michael Y H Soon
    Department of Orthopaedic Surgery, Alexandra Hospital, Singapore
    Am J Sports Med 35:962-71. 2007

Collaborators

Detail Information

Publications18

  1. doi request reprint Cartilage repair: 2013 Asian update
    James H P Hui
    Cartilage Repair Program, Therapeutic Tissue Engineering Laboratory, Department of Orthopaedic Surgery, National University Health System, National University of Singapore, Singapore Electronic address
    Arthroscopy 29:1992-2000. 2013
    ..Finally, we make a few suggestions on the direction of research and development activities and the need for collaborative approaches by regulatory agencies...
  2. pmc Oligo[poly(ethylene glycol)fumarate] hydrogel enhances osteochondral repair in porcine femoral condyle defects
    James H Hui
    Cartilage Repair Program, Therapeutic Tissue Engineering Laboratory, Department of Orthopaedic Surgery, National University Health System, National University Hospital, Yong Loo Lin School of Medicine, National University of Singapore, 1E, Kent Ridge Road, Singapore, 119288, Singapore
    Clin Orthop Relat Res 471:1174-85. 2013
    ..However, preclinical evaluation of usage of this scaffold alone as a treatment strategy is limited...
  3. doi request reprint Implantation of orthobiologic, biodegradable scaffolds in osteochondral repair
    James H P Hui
    Division of Paediatric Orthopaedics, National University Hospital, 5, Lower Kent Ridge Road, Kent Ridge Wing 2, Level 3, 119074, Singapore
    Orthop Clin North Am 43:255-61, vii. 2012
    ..Third-generation cell-based therapies such as the use of tissue engineered scaffolds need to be studied in more detail...
  4. pmc Improved mesenchymal stem cells attachment and in vitro cartilage tissue formation on chitosan-modified poly(L-lactide-co-epsilon-caprolactone) scaffold
    Zheng Yang
    Tissue Engineering Program, Life Sciences Institute, National University of Singapore, Singapore
    Tissue Eng Part A 18:242-51. 2012
    ....
  5. ncbi request reprint 11th Yahya Cohen Memorial Lecture: An in vivo comparative study of the ability of derived mesenchymal stem cells in the treatment of partial growth arrest
    James H P Hui
    Department of Orthopaedic Surgery, National University of Singapore, Singapore
    Ann Acad Med Singapore 38:84-7. 2009
    ..01). In conclusion, bone marrow and periosteum derived stem cells provided better correction of physeal arrest in rabbits. The source of MSCs itself could influence the success in the treatment of growth arrest...
  6. ncbi request reprint A comparison between the chondrogenic potential of human bone marrow stem cells (BMSCs) and adipose-derived stem cells (ADSCs) taken from the same donors
    Hassan Afizah
    Department of Orthopaedic Surgery, National University of Singapore, Singapore
    Tissue Eng 13:659-66. 2007
    ..These findings support the results obtained in our in vivo comparative study done on an animal model, suggesting that BMSCs are more suitable than adipose-derived stem cells (ADSCs) for chondrogenesis...
  7. ncbi request reprint Cartilaginous ECM component-modification of the micro-bead culture system for chondrogenic differentiation of mesenchymal stem cells
    Ying Nan Wu
    Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore NUS Tissue Engineering Program NUSTEP, National University Hospital, Lower Kent Ridge Road, Singapore 119074, Republic of Singapore
    Biomaterials 28:4056-67. 2007
    ....
  8. ncbi request reprint A novel, minimally-invasive technique of cartilage repair in the human knee using arthroscopic microfracture and injections of mesenchymal stem cells and hyaluronic acid--a prospective comparative study on safety and short-term efficacy
    Kevin B L Lee
    Department of Orthopaedic Surgery, National University Hospital, Singapore
    Ann Acad Med Singapore 41:511-7. 2012
    ....
  9. doi request reprint Injectable cultured bone marrow-derived mesenchymal stem cells in varus knees with cartilage defects undergoing high tibial osteotomy: a prospective, randomized controlled clinical trial with 2 years' follow-up
    Keng Lin Wong
    Department of Orthopaedic Surgery, University Orthopaedic, Hand and Reconstructive Microsurgery Cluster, National University Health System, Singapore
    Arthroscopy 29:2020-8. 2013
    ..To analyze the results of the use of intra-articular cultured autologous bone marrow-derived mesenchymal stem cell (MSC) injections in conjunction with microfracture and medial opening-wedge high tibial osteotomy (HTO)...
  10. ncbi request reprint An analysis of soft tissue allograft anterior cruciate ligament reconstruction in a rabbit model: a short-term study of the use of mesenchymal stem cells to enhance tendon osteointegration
    Michael Y H Soon
    Department of Orthopaedic Surgery, Alexandra Hospital, Singapore
    Am J Sports Med 35:962-71. 2007
    ..However, the use of allografts is associated with a higher failure rate of osteointegration. Mesenchymal stem cells (MSCs) are investigated as potential agents to enhance bone tunnel and tendon healing...
  11. ncbi request reprint Injectable mesenchymal stem cell therapy for large cartilage defects--a porcine model
    Kevin B L Lee
    Department of Orthopaedic Surgery, National University of Singapore, Lower Kent Ridge Road, Singapore 119074, Republic of Singapore
    Stem Cells 25:2964-71. 2007
    ..The use of intra-articular injections of mesenchymal stem cells suspended in HA is a viable option for treating large cartilage defects. This would be further explored in clinical trials...
  12. doi request reprint The effect of fibrin glue on tendon healing and adhesion formation in a rabbit model of flexor tendon injury and repair
    Min He
    Hand and Reconstructive Microsurgery, National University Hospital, Singapore
    J Plast Surg Hand Surg 47:509-12. 2013
    ..However, there is no significant effect on biomechanical features during tendon repair. In conclusion, this study has shown that it may be safe to use TISSEEL in tissue engineering applications for tendon regeneration and healing...
  13. doi request reprint Demographics and clinical presentation of slipped capital femoral epiphysis in Singapore: comparing the East with the West
    Yi Jia Lim
    Department of Orthopaedic Surgery, Changi General Hospital, Singapore
    J Pediatr Orthop B 17:289-92. 2008
    ..A high proportion of patients were obese. Our incidence of bilateral involvement seems to be higher than our Indonesian neighbors. The differences seen may be due to genetic and sociocultural variations...
  14. doi request reprint The potential of human fetal mesenchymal stem cells for off-the-shelf bone tissue engineering application
    Zhi Yong Zhang
    Mechanical Engineering, Faculty of Engineering, National University of Singapore, Singapore
    Biomaterials 33:2656-72. 2012
    ..In conclusion, hfMSC is likely the most promising cell source for allogeneic based BTE application, with proven advantages compared to other MSC based ones...
  15. ncbi request reprint Comparative study of the ability of mesenchymal stem cells derived from bone marrow, periosteum, and adipose tissue in treatment of partial growth arrest in rabbit
    James H P Hui
    Department of Orthopedic Surgery, National University of Singapore, Singapore
    Tissue Eng 11:904-12. 2005
    ..01). In conclusion, bone-marrow and periosteum yielded more homogenous MSCs than fat, providing better correction of physeal arrest in rabbits. The source of MSCs itself could influence the success in the treatment of growth arrest...
  16. ncbi request reprint Osteoid osteoma: a current review
    Eng Hin Lee
    Department of Orthopaedic Surgery, National University of Singapore, Singapore
    J Pediatr Orthop 26:695-700. 2006
  17. ncbi request reprint Mesenchymal stem cell therapy for injured growth plate
    Awang B Shukrimi
    Department of Orthopaedic Surgery, National University Health System, National University of Singapore, Singapore
    Front Biosci (Schol Ed) 5:774-85. 2013
    ..Possible further studies to optimize physeal repair based on MSC therapy in articular cartilage are also included...
  18. ncbi request reprint Recurrent patellar dislocation: reappraising our approach to surgery
    Andrew K S Lim
    Department of Orthopaedic Surgery, National University Hospital, Singapore
    Ann Acad Med Singapore 37:320-3. 2008
    ..However, distal realignment procedures are commonly associated with greater morbidity. We advocate a distal procedure only for cases which are more severe, such as the presence of patellar maltracking...