Eng-Eong Ooi

Summary

Affiliation: DSO National Laboratories
Country: Singapore

Publications

  1. ncbi request reprint Dengue in Southeast Asia: epidemiological characteristics and strategic challenges in disease prevention
    Eng Eong Ooi
    DSO National Laboratories, Singapore
    Cad Saude Publica 25:S115-24. 2009
  2. pmc Decision tree algorithms predict the diagnosis and outcome of dengue fever in the early phase of illness
    Lukas Tanner
    Novartis Institute for Tropical Diseases, Singapore
    PLoS Negl Trop Dis 2:e196. 2008
  3. pmc Neutralizing human monoclonal antibody against H5N1 influenza HA selected from a Fab-phage display library
    Angeline P C Lim
    Defence Medical and Environmental Research Institute, DSO National Laboratories, 27 Medical Dr, 117510, Singapore
    Virol J 5:130. 2008
  4. pmc Epitope characterization of the protective monoclonal antibody VN04-2 shows broadly neutralizing activity against highly pathogenic H5N1
    Angeline P C Lim
    Defence Medical and Environmental Research Institute, DSO National Laboratories, 27 Medical Dr, 117510, Singapore
    Virol J 5:80. 2008
  5. pmc Passive immunoprophylaxis and therapy with humanized monoclonal antibody specific for influenza A H5 hemagglutinin in mice
    Brendon J Hanson
    Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore 117510
    Respir Res 7:126. 2006
  6. pmc Dengue prevention and 35 years of vector control in Singapore
    Eng Eong Ooi
    Defense Medical and Environmental Research Institute, DSO National Laboratories, Singapore
    Emerg Infect Dis 12:887-93. 2006
  7. pmc In vitro inhibition of human influenza A virus replication by chloroquine
    Eng Eong Ooi
    Defence Medical and Environmental Research Institute, DSO National Laboratories, 27 Medical Drive, 09 01, 117510, Singapore
    Virol J 3:39. 2006
  8. doi request reprint Burkholderia pseudomallei aerosol infection results in differential inflammatory responses in BALB/c and C57Bl/6 mice
    Gek Yen Gladys Tan
    Medical Countermeasures Laboratory, DSO National Laboratories, Singapore 117510
    J Med Microbiol 57:508-15. 2008
  9. pmc Cost-effective real-time reverse transcriptase PCR (RT-PCR) to screen for Dengue virus followed by rapid single-tube multiplex RT-PCR for serotyping of the virus
    Yee Ling Lai
    National Environment Agency, Environmental Health Institute, 11 Biopolis Way, 06 05 08 Helios Block, Singapore 138667
    J Clin Microbiol 45:935-41. 2007
  10. ncbi request reprint Early Dengue infection and outcome study (EDEN) - study design and preliminary findings
    Jenny G H Low
    Department of Infectious Diseases, Communicable Disease Centre, Tock Seng Hospital, Singapore
    Ann Acad Med Singapore 35:783-9. 2006

Collaborators

  • Duane J Gubler
  • Subhash G Vasudevan
  • Lee Ching Ng
  • Jenny G H Low
  • Cameron P Simmons
  • Adrian Ong
  • Kee-Tai Goh
  • Li Yang Hsu
  • Thomas Tolfvenstam
  • Angeline P C Lim
  • Brendon J Hanson
  • Yee Ling Lai
  • Steven K K Wong
  • Conrad E Z Chan
  • Lukas Tanner
  • Annie H Y Chan
  • Gek Yen Gladys Tan
  • Yin Ling Koh
  • Pierce K H Chow
  • Suppiah Paramalingal Sivalingam
  • Le Thi Puong
  • Yee Sin Leo
  • Mark Schreiber
  • Dongling Wang
  • Jean Charles Paucod
  • Yichun Liu
  • Yves Gauthier
  • Martin L Hibberd
  • Siew Hoon Sim
  • Grace Yap
  • Hwee Cheng Tan
  • Hoon Fang Yap
  • Youne Kow Chung
  • Ashley Webb
  • Richard J Webby
  • Jimmy Jin Phang Loh
  • Sheng Yong Su
  • Boon Huan Tan
  • Adrianus C M Boon
  • Khee Chee Soo
  • Hiang Khoon Tan
  • Bijon Kumar Sil
  • Melissa Teo
  • Timothy Ng
  • Kong Wee Ong

Detail Information

Publications14

  1. ncbi request reprint Dengue in Southeast Asia: epidemiological characteristics and strategic challenges in disease prevention
    Eng Eong Ooi
    DSO National Laboratories, Singapore
    Cad Saude Publica 25:S115-24. 2009
    ..A regional approach would also result in a greater likelihood of success in disease prevention since the large volume of human travel is a major factor contributing to the geographical spread of dengue viruses...
  2. pmc Decision tree algorithms predict the diagnosis and outcome of dengue fever in the early phase of illness
    Lukas Tanner
    Novartis Institute for Tropical Diseases, Singapore
    PLoS Negl Trop Dis 2:e196. 2008
    ..Here we report the identification of algorithms that differentiate dengue from other febrile illnesses in the primary care setting and predict severe disease in adults...
  3. pmc Neutralizing human monoclonal antibody against H5N1 influenza HA selected from a Fab-phage display library
    Angeline P C Lim
    Defence Medical and Environmental Research Institute, DSO National Laboratories, 27 Medical Dr, 117510, Singapore
    Virol J 5:130. 2008
    ....
  4. pmc Epitope characterization of the protective monoclonal antibody VN04-2 shows broadly neutralizing activity against highly pathogenic H5N1
    Angeline P C Lim
    Defence Medical and Environmental Research Institute, DSO National Laboratories, 27 Medical Dr, 117510, Singapore
    Virol J 5:80. 2008
    ....
  5. pmc Passive immunoprophylaxis and therapy with humanized monoclonal antibody specific for influenza A H5 hemagglutinin in mice
    Brendon J Hanson
    Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore 117510
    Respir Res 7:126. 2006
    ..Humanized monoclonal antibodies (mAbs) that neutralize H5N1 virus could be used as prophylaxis and treatment to aid in the containment of such a pandemic...
  6. pmc Dengue prevention and 35 years of vector control in Singapore
    Eng Eong Ooi
    Defense Medical and Environmental Research Institute, DSO National Laboratories, Singapore
    Emerg Infect Dis 12:887-93. 2006
    ..Singapore's taking on a leadership role in strengthening disease surveillance and control in Southeast Asia may also be useful in reducing virus importation...
  7. pmc In vitro inhibition of human influenza A virus replication by chloroquine
    Eng Eong Ooi
    Defence Medical and Environmental Research Institute, DSO National Laboratories, 27 Medical Drive, 09 01, 117510, Singapore
    Virol J 3:39. 2006
    ..The potential of chloroquine to be added to the limited range of anti-influenza drugs should be explored further, particularly since antiviral drugs play a vital role in influenza pandemic preparedness...
  8. doi request reprint Burkholderia pseudomallei aerosol infection results in differential inflammatory responses in BALB/c and C57Bl/6 mice
    Gek Yen Gladys Tan
    Medical Countermeasures Laboratory, DSO National Laboratories, Singapore 117510
    J Med Microbiol 57:508-15. 2008
    ..This suggests that high levels of proinflammatory cytokines are detrimental and contribute to the immunopathogenesis of the infection...
  9. pmc Cost-effective real-time reverse transcriptase PCR (RT-PCR) to screen for Dengue virus followed by rapid single-tube multiplex RT-PCR for serotyping of the virus
    Yee Ling Lai
    National Environment Agency, Environmental Health Institute, 11 Biopolis Way, 06 05 08 Helios Block, Singapore 138667
    J Clin Microbiol 45:935-41. 2007
    ..The serotyping results derived from duplex and fourplex assays agree fully with each other and with that derived from immunofluorescence assays...
  10. ncbi request reprint Early Dengue infection and outcome study (EDEN) - study design and preliminary findings
    Jenny G H Low
    Department of Infectious Diseases, Communicable Disease Centre, Tock Seng Hospital, Singapore
    Ann Acad Med Singapore 35:783-9. 2006
    ..Hence, the World Health Organization (WHO) guidelines on dengue diagnosis and management which were developed using the paediatric experiences, may not be suitable for the management of adult dengue infections...
  11. pmc Japanese encephalitis, Singapore
    Yin Ling Koh
    Emerg Infect Dis 12:525-6. 2006
  12. pmc A human in vitro model system for investigating genome-wide host responses to SARS coronavirus infection
    Lisa F P Ng
    Genome Institute of Singapore, 60 Biopolis Street, Genome, 02 01, Singapore 138672
    BMC Infect Dis 4:34. 2004
    ..In this study, we therefore examine the immune response of SARS-CoV in human peripheral blood mononuclear cells (PBMCs) over the first 24 hours...
  13. pmc Healthcare worker seroconversion in SARS outbreak
    Pierce K H Chow
    Department of General Surgery, Singapore General Hospital, Singapore
    Emerg Infect Dis 10:249-50. 2004
    ....
  14. pmc Seroepidemiology of human enterovirus 71, Singapore
    Eng Eong Ooi
    Environmental Health Institute, National Environment Agency, Singapore
    Emerg Infect Dis 8:995-7. 2002
    ..The epidemiology of this viral infection is not well understood. We conducted a serologic survey in Singapore children, and the results indicate that infection occurs largely in preschool settings...