Sonia Davila

Summary

Country: Singapore

Publications

  1. pmc Mutations in PRKCSH cause isolated autosomal dominant polycystic liver disease
    Airong Li
    Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06519, USA
    Am J Hum Genet 72:691-703. 2003
  2. pmc Genome-wide association studies are coming for human infectious diseases
    Sonia Davila
    Genome Institute of Singapore, Infectious Diseases, 60 Biopolis Street, 138672 Singapore
    Genome Med 1:19. 2009
  3. pmc Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis
    Sonia Davila
    Infectious Diseases, Genome Institute of Singapore, Singapore, Singapore
    PLoS Genet 4:e1000218. 2008
  4. doi request reprint Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease
    Sonia Davila
    Infectious Diseases, Genome Institute of Singapore, Singapore
    Nat Genet 42:772-6. 2010
  5. doi request reprint Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease
    Chiea Chuen Khor
    Infectious Diseases, Genome Institute of Singapore, Singapore
    Nat Genet 43:1241-6. 2011
  6. doi request reprint Genome-wide linkage and association mapping identify susceptibility alleles in ABCC4 for Kawasaki disease
    Chiea Chuen Khor
    Division of Infectious Diseases, Genome Institute of Singapore, Singapore
    J Med Genet 48:467-72. 2011
  7. pmc Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1
    Chiea Chuen Khor
    Infectious Diseases, Genome Institute of Singapore, Singapore
    Nat Genet 43:1139-41. 2011

Detail Information

Publications7

  1. pmc Mutations in PRKCSH cause isolated autosomal dominant polycystic liver disease
    Airong Li
    Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06519, USA
    Am J Hum Genet 72:691-703. 2003
    ..In light of the focal nature of liver cysts in ADPLD, the apparent loss-of-function mutations in PRKCSH, and the two-hit mechanism operational in dominant polycystic kidney disease, ADPLD may also occur by a two-hit mechanism...
  2. pmc Genome-wide association studies are coming for human infectious diseases
    Sonia Davila
    Genome Institute of Singapore, Infectious Diseases, 60 Biopolis Street, 138672 Singapore
    Genome Med 1:19. 2009
    ....
  3. pmc Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis
    Sonia Davila
    Infectious Diseases, Genome Institute of Singapore, Singapore, Singapore
    PLoS Genet 4:e1000218. 2008
    ..bovis bacille Calmette-Guérin (BCG). Taken together, our results provide evidence, for the first time, of a role for the TLR8 gene in susceptibility to pulmonary TB across different populations...
  4. doi request reprint Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease
    Sonia Davila
    Infectious Diseases, Genome Institute of Singapore, Singapore
    Nat Genet 42:772-6. 2010
    ..Our study suggests that host genetic variation in these regulators of complement activation plays a role in determining the occurrence of invasive disease versus asymptomatic colonization by this pathogen...
  5. doi request reprint Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease
    Chiea Chuen Khor
    Infectious Diseases, Genome Institute of Singapore, Singapore
    Nat Genet 43:1241-6. 2011
    ..The involvement of the FCGR2A locus may have implications for understanding immune activation in Kawasaki disease pathogenesis and the mechanism of response to intravenous immunoglobulin, the only proven therapy for this disease...
  6. doi request reprint Genome-wide linkage and association mapping identify susceptibility alleles in ABCC4 for Kawasaki disease
    Chiea Chuen Khor
    Division of Infectious Diseases, Genome Institute of Singapore, Singapore
    J Med Genet 48:467-72. 2011
    ....
  7. pmc Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1
    Chiea Chuen Khor
    Infectious Diseases, Genome Institute of Singapore, Singapore
    Nat Genet 43:1139-41. 2011
    ..08 × 10(-10), per-allele OR = 0.80 (95% confidence interval: 0.75-0.86)). We identify two loci associated with susceptibility to DSS in people with dengue, suggesting possible mechanisms for this severe complication of dengue...