Surajit Das

Summary

Country: Singapore

Publications

  1. doi request reprint Polyethyleneimine-modified pectin beads for colon-specific drug delivery: in vitro and in vivo implications
    Surajit Das
    Department of Pharmacy, National University of Singapore, Singapore, Republic of Singapore
    J Microencapsul 28:268-79. 2011
  2. pmc Recent advances in lipid nanoparticle formulations with solid matrix for oral drug delivery
    Surajit Das
    Institute of Chemical and Engineering Sciences, Agency for Science, Technology and Research, 1 Pesek Road, Jurong Island, Singapore, 627833, Republic of Singapore
    AAPS PharmSciTech 12:62-76. 2011
  3. doi request reprint Formulation design, preparation and physicochemical characterizations of solid lipid nanoparticles containing a hydrophobic drug: effects of process variables
    Surajit Das
    Institute of Chemical and Engineering Sciences, A STAR Agency for Science, Technology and Research, Jurong Island, Singapore, Singapore
    Colloids Surf B Biointerfaces 88:483-9. 2011
  4. doi request reprint Impact of glutaraldehyde on in vivo colon-specific release of resveratrol from biodegradable pectin-based formulation
    Surajit Das
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Republic of Singapore
    J Pharm Sci 99:4903-16. 2010
  5. doi request reprint Lyophilization of cholesterol-free PEGylated liposomes and its impact on drug loading by passive equilibration
    Anumita Chaudhury
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore
    Int J Pharm 430:167-75. 2012
  6. doi request reprint Colon-specific delivery of resveratrol: optimization of multi-particulate calcium-pectinate carrier
    Surajit Das
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Republic of Singapore
    Int J Pharm 385:20-8. 2010
  7. doi request reprint Design of a pectin-based microparticle formulation using zinc ions as the cross-linking agent and glutaraldehyde as the hardening agent for colonic-specific delivery of resveratrol: in vitro and in vivo evaluations
    Surajit Das
    Department of Pharmacy, National University of Singapore
    J Drug Target 19:446-57. 2011
  8. doi request reprint Preparation and evaluation of zinc-pectin-chitosan composite particles for drug delivery to the colon: role of chitosan in modifying in vitro and in vivo drug release
    Surajit Das
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Republic of Singapore surajit
    Int J Pharm 406:11-20. 2011
  9. doi request reprint Formulation, biological and pharmacokinetic studies of sucrose ester-stabilized nanosuspensions of oleanolic Acid
    Wenji Li
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore
    Pharm Res 28:2020-33. 2011
  10. doi request reprint Are nanostructured lipid carriers (NLCs) better than solid lipid nanoparticles (SLNs): development, characterizations and comparative evaluations of clotrimazole-loaded SLNs and NLCs?
    Surajit Das
    Institute of Chemical and Engineering Sciences, A STAR Agency for Science, Technology and Research, 1 Pesek Road, Jurong Island, Singapore 627833, Singapore
    Eur J Pharm Sci 47:139-51. 2012

Detail Information

Publications16

  1. doi request reprint Polyethyleneimine-modified pectin beads for colon-specific drug delivery: in vitro and in vivo implications
    Surajit Das
    Department of Pharmacy, National University of Singapore, Singapore, Republic of Singapore
    J Microencapsul 28:268-79. 2011
    ..Furthermore, in vivo pharmacokinetics studies in rats demonstrated delayed appearance of drug in blood after oral administration. The optimized Ca-pectinate beads demonstrated both in vitro and in vivo colon-specific drug release...
  2. pmc Recent advances in lipid nanoparticle formulations with solid matrix for oral drug delivery
    Surajit Das
    Institute of Chemical and Engineering Sciences, Agency for Science, Technology and Research, 1 Pesek Road, Jurong Island, Singapore, 627833, Republic of Singapore
    AAPS PharmSciTech 12:62-76. 2011
    ....
  3. doi request reprint Formulation design, preparation and physicochemical characterizations of solid lipid nanoparticles containing a hydrophobic drug: effects of process variables
    Surajit Das
    Institute of Chemical and Engineering Sciences, A STAR Agency for Science, Technology and Research, Jurong Island, Singapore, Singapore
    Colloids Surf B Biointerfaces 88:483-9. 2011
    ..Furthermore, tretinoin-loaded SLNs were stable for 3 months at 4°C. Hence, the developed SLNs can be used as drug carrier for sustained/prolonged drug release and/or to improve oral absorption/bioavailability...
  4. doi request reprint Impact of glutaraldehyde on in vivo colon-specific release of resveratrol from biodegradable pectin-based formulation
    Surajit Das
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Republic of Singapore
    J Pharm Sci 99:4903-16. 2010
    ..Hence, the developed formulation has potential to be used as colon-specific delivery system of resveratrol...
  5. doi request reprint Lyophilization of cholesterol-free PEGylated liposomes and its impact on drug loading by passive equilibration
    Anumita Chaudhury
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore
    Int J Pharm 430:167-75. 2012
    ..Taken together, we envisioned that a stable, lyophilized empty CF-PEG liposome system could be coupled to hydrophilic drug loading via the passive equilibration method to produce a liposomal drug kit product...
  6. doi request reprint Colon-specific delivery of resveratrol: optimization of multi-particulate calcium-pectinate carrier
    Surajit Das
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Republic of Singapore
    Int J Pharm 385:20-8. 2010
    ..Observations from the present study revealed that optimized Ca-pectinate beads hardened with PEI can efficiently encapsulate resveratrol and have potential for colon-specific delivery to the lower GI tract...
  7. doi request reprint Design of a pectin-based microparticle formulation using zinc ions as the cross-linking agent and glutaraldehyde as the hardening agent for colonic-specific delivery of resveratrol: in vitro and in vivo evaluations
    Surajit Das
    Department of Pharmacy, National University of Singapore
    J Drug Target 19:446-57. 2011
    ....
  8. doi request reprint Preparation and evaluation of zinc-pectin-chitosan composite particles for drug delivery to the colon: role of chitosan in modifying in vitro and in vivo drug release
    Surajit Das
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Republic of Singapore surajit
    Int J Pharm 406:11-20. 2011
    ..Microparticles were stable at 4 °C and room temperature. Pharmacokinetic study indicated in vivo colon-specific drug release from the zinc-pectin-chitosan composite particles only...
  9. doi request reprint Formulation, biological and pharmacokinetic studies of sucrose ester-stabilized nanosuspensions of oleanolic Acid
    Wenji Li
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore
    Pharm Res 28:2020-33. 2011
    ..The aim of this study was to develop sucrose ester (SE)-stabilized oleanolic acid (OA) nanosuspensions (NS) for enhanced delivery...
  10. doi request reprint Are nanostructured lipid carriers (NLCs) better than solid lipid nanoparticles (SLNs): development, characterizations and comparative evaluations of clotrimazole-loaded SLNs and NLCs?
    Surajit Das
    Institute of Chemical and Engineering Sciences, A STAR Agency for Science, Technology and Research, 1 Pesek Road, Jurong Island, Singapore 627833, Singapore
    Eur J Pharm Sci 47:139-51. 2012
    ..Therefore, NLCs have an edge over SLNs...
  11. pmc Formulation and optimization of zinc-pectinate beads for the controlled delivery of resveratrol
    Surajit Das
    Department of Pharmacy, Faculty of Science, National University of Singapore, Block S4, 18 Science Drive 4, Singapore, 117543, Republic of Singapore
    AAPS PharmSciTech 11:729-42. 2010
    ..This study demonstrates that the optimized Zn-pectinate beads can encapsulate very high amount of resveratrol and can be used as delayed release formulation of resveratrol...
  12. doi request reprint Resveratrol-loaded calcium-pectinate beads: effects of formulation parameters on drug release and bead characteristics
    Surajit Das
    Faculty of Science, Department of Pharmacy, National University of Singapore, Singapore
    J Pharm Sci 99:840-60. 2010
    ..5%) and can be used for delayed release and site-specific delivery to the lower GI tract. Depending on the formulation parameters, release of resveratrol after 10 h incubation in the intestinal media was 80-100%...
  13. pmc Recent advancement of chitosan-based nanoparticles for oral controlled delivery of insulin and other therapeutic agents
    Anumita Chaudhury
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore, 117543, Republic of Singapore
    AAPS PharmSciTech 12:10-20. 2011
    ..The current review focuses on the recent advancements in the field of oral controlled release via chitosan nanoparticles and discusses about its in vitro and in vivo implications...
  14. pmc Potent therapeutic activity of folate receptor-targeted liposomal carboplatin in the localized treatment of intraperitoneally grown human ovarian tumor xenograft
    Anumita Chaudhury
    Department of Pharmacy, National University of Singapore
    Int J Nanomedicine 7:739-51. 2012
    ....
  15. doi request reprint Increased ERK activation and cellular drug accumulation in the enhanced cytotoxicity of folate receptor-targeted liposomal carboplatin
    Anumita Chaudhury
    Department of Pharmacy, National University of Singapore, Singapore
    Int J Oncol 40:703-10. 2012
    ..Collectively, the current study suggests a novel mechanism by which FRT liposomes could sensitize cancer cells to drug treatment via modulation of ERK-related cell survival signals...
  16. doi request reprint The impact of aqueous solubility and dose on the pharmacokinetic profiles of resveratrol
    Surajit Das
    Department of Pharmacy, Faculty of Science, National University of Singapore, Building S4, Rm 05 02, 18 Science Drive 4, Singapore 117543, Singapore
    Pharm Res 25:2593-600. 2008
    ..This study aimed at the investigation of the impact of aqueous solubility and dose manipulation on the pharmacokinetics of resveratrol...