Surajit Das

Summary

Country: Singapore

Publications

  1. doi Polyethyleneimine-modified pectin beads for colon-specific drug delivery: in vitro and in vivo implications
    Surajit Das
    Department of Pharmacy, National University of Singapore, Singapore, Republic of Singapore
    J Microencapsul 28:268-79. 2011
  2. doi Formulation design, preparation and physicochemical characterizations of solid lipid nanoparticles containing a hydrophobic drug: effects of process variables
    Surajit Das
    Institute of Chemical and Engineering Sciences, A STAR Agency for Science, Technology and Research, Jurong Island, Singapore, Singapore
    Colloids Surf B Biointerfaces 88:483-9. 2011
  3. pmc Recent advances in lipid nanoparticle formulations with solid matrix for oral drug delivery
    Surajit Das
    Institute of Chemical and Engineering Sciences, Agency for Science, Technology and Research, 1 Pesek Road, Jurong Island, Singapore, 627833, Republic of Singapore
    AAPS PharmSciTech 12:62-76. 2011
  4. doi Impact of glutaraldehyde on in vivo colon-specific release of resveratrol from biodegradable pectin-based formulation
    Surajit Das
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Republic of Singapore
    J Pharm Sci 99:4903-16. 2010
  5. doi Lyophilization of cholesterol-free PEGylated liposomes and its impact on drug loading by passive equilibration
    Anumita Chaudhury
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore
    Int J Pharm 430:167-75. 2012
  6. doi Colon-specific delivery of resveratrol: optimization of multi-particulate calcium-pectinate carrier
    Surajit Das
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Republic of Singapore
    Int J Pharm 385:20-8. 2010
  7. doi Design of a pectin-based microparticle formulation using zinc ions as the cross-linking agent and glutaraldehyde as the hardening agent for colonic-specific delivery of resveratrol: in vitro and in vivo evaluations
    Surajit Das
    Department of Pharmacy, National University of Singapore
    J Drug Target 19:446-57. 2011
  8. doi Preparation and evaluation of zinc-pectin-chitosan composite particles for drug delivery to the colon: role of chitosan in modifying in vitro and in vivo drug release
    Surajit Das
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Republic of Singapore surajit
    Int J Pharm 406:11-20. 2011
  9. doi Formulation, biological and pharmacokinetic studies of sucrose ester-stabilized nanosuspensions of oleanolic Acid
    Wenji Li
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore
    Pharm Res 28:2020-33. 2011
  10. doi Are nanostructured lipid carriers (NLCs) better than solid lipid nanoparticles (SLNs): development, characterizations and comparative evaluations of clotrimazole-loaded SLNs and NLCs?
    Surajit Das
    Institute of Chemical and Engineering Sciences, A STAR Agency for Science, Technology and Research, 1 Pesek Road, Jurong Island, Singapore 627833, Singapore
    Eur J Pharm Sci 47:139-51. 2012

Detail Information

Publications18

  1. doi Polyethyleneimine-modified pectin beads for colon-specific drug delivery: in vitro and in vivo implications
    Surajit Das
    Department of Pharmacy, National University of Singapore, Singapore, Republic of Singapore
    J Microencapsul 28:268-79. 2011
    ..Furthermore, in vivo pharmacokinetics studies in rats demonstrated delayed appearance of drug in blood after oral administration. The optimized Ca-pectinate beads demonstrated both in vitro and in vivo colon-specific drug release...
  2. doi Formulation design, preparation and physicochemical characterizations of solid lipid nanoparticles containing a hydrophobic drug: effects of process variables
    Surajit Das
    Institute of Chemical and Engineering Sciences, A STAR Agency for Science, Technology and Research, Jurong Island, Singapore, Singapore
    Colloids Surf B Biointerfaces 88:483-9. 2011
    ..Furthermore, tretinoin-loaded SLNs were stable for 3 months at 4°C. Hence, the developed SLNs can be used as drug carrier for sustained/prolonged drug release and/or to improve oral absorption/bioavailability...
  3. pmc Recent advances in lipid nanoparticle formulations with solid matrix for oral drug delivery
    Surajit Das
    Institute of Chemical and Engineering Sciences, Agency for Science, Technology and Research, 1 Pesek Road, Jurong Island, Singapore, 627833, Republic of Singapore
    AAPS PharmSciTech 12:62-76. 2011
    ....
  4. doi Impact of glutaraldehyde on in vivo colon-specific release of resveratrol from biodegradable pectin-based formulation
    Surajit Das
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Republic of Singapore
    J Pharm Sci 99:4903-16. 2010
    ..Hence, the developed formulation has potential to be used as colon-specific delivery system of resveratrol...
  5. doi Lyophilization of cholesterol-free PEGylated liposomes and its impact on drug loading by passive equilibration
    Anumita Chaudhury
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore
    Int J Pharm 430:167-75. 2012
    ..Taken together, we envisioned that a stable, lyophilized empty CF-PEG liposome system could be coupled to hydrophilic drug loading via the passive equilibration method to produce a liposomal drug kit product...
  6. doi Colon-specific delivery of resveratrol: optimization of multi-particulate calcium-pectinate carrier
    Surajit Das
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Republic of Singapore
    Int J Pharm 385:20-8. 2010
    ..Observations from the present study revealed that optimized Ca-pectinate beads hardened with PEI can efficiently encapsulate resveratrol and have potential for colon-specific delivery to the lower GI tract...
  7. doi Design of a pectin-based microparticle formulation using zinc ions as the cross-linking agent and glutaraldehyde as the hardening agent for colonic-specific delivery of resveratrol: in vitro and in vivo evaluations
    Surajit Das
    Department of Pharmacy, National University of Singapore
    J Drug Target 19:446-57. 2011
    ....
  8. doi Preparation and evaluation of zinc-pectin-chitosan composite particles for drug delivery to the colon: role of chitosan in modifying in vitro and in vivo drug release
    Surajit Das
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Republic of Singapore surajit
    Int J Pharm 406:11-20. 2011
    ..Microparticles were stable at 4 °C and room temperature. Pharmacokinetic study indicated in vivo colon-specific drug release from the zinc-pectin-chitosan composite particles only...
  9. doi Formulation, biological and pharmacokinetic studies of sucrose ester-stabilized nanosuspensions of oleanolic Acid
    Wenji Li
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore
    Pharm Res 28:2020-33. 2011
    ..The aim of this study was to develop sucrose ester (SE)-stabilized oleanolic acid (OA) nanosuspensions (NS) for enhanced delivery...
  10. doi Are nanostructured lipid carriers (NLCs) better than solid lipid nanoparticles (SLNs): development, characterizations and comparative evaluations of clotrimazole-loaded SLNs and NLCs?
    Surajit Das
    Institute of Chemical and Engineering Sciences, A STAR Agency for Science, Technology and Research, 1 Pesek Road, Jurong Island, Singapore 627833, Singapore
    Eur J Pharm Sci 47:139-51. 2012
    ..Therefore, NLCs have an edge over SLNs...
  11. pmc Formulation and optimization of zinc-pectinate beads for the controlled delivery of resveratrol
    Surajit Das
    Department of Pharmacy, Faculty of Science, National University of Singapore, Block S4, 18 Science Drive 4, Singapore, 117543, Republic of Singapore
    AAPS PharmSciTech 11:729-42. 2010
    ..This study demonstrates that the optimized Zn-pectinate beads can encapsulate very high amount of resveratrol and can be used as delayed release formulation of resveratrol...
  12. doi Resveratrol-loaded calcium-pectinate beads: effects of formulation parameters on drug release and bead characteristics
    Surajit Das
    Faculty of Science, Department of Pharmacy, National University of Singapore, Singapore
    J Pharm Sci 99:840-60. 2010
    ..5%) and can be used for delayed release and site-specific delivery to the lower GI tract. Depending on the formulation parameters, release of resveratrol after 10 h incubation in the intestinal media was 80-100%...
  13. pmc Recent advancement of chitosan-based nanoparticles for oral controlled delivery of insulin and other therapeutic agents
    Anumita Chaudhury
    Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore, 117543, Republic of Singapore
    AAPS PharmSciTech 12:10-20. 2011
    ..The current review focuses on the recent advancements in the field of oral controlled release via chitosan nanoparticles and discusses about its in vitro and in vivo implications...
  14. pmc Potent therapeutic activity of folate receptor-targeted liposomal carboplatin in the localized treatment of intraperitoneally grown human ovarian tumor xenograft
    Anumita Chaudhury
    Department of Pharmacy, National University of Singapore
    Int J Nanomedicine 7:739-51. 2012
    ....
  15. doi Sucrose ester stabilized solid lipid nanoparticles and nanostructured lipid carriers. I. Effect of formulation variables on the physicochemical properties, drug release and stability of clotrimazole-loaded nanoparticles
    Surajit Das
    Institute of Chemical and Engineering Sciences, A STAR Agency for Science, Technology and Research, 1 Pesek Road, Jurong Island, Singapore 627833, Singapore
    Nanotechnology 25:105101. 2014
    ..The results indicated that both SLNs and NLCs stabilized with sucrose ester D-1216 can be used as controlled release carriers although NLCs have an edge over SLNs...
  16. doi Sucrose ester stabilized solid lipid nanoparticles and nanostructured lipid carriers. II. Evaluation of the imidazole antifungal drug-loaded nanoparticle dispersions and their gel formulations
    Surajit Das
    Institute of Chemical and Engineering Sciences, A STAR Agency for Science, Technology and Research, 1 Pesek Road, Jurong Island, Singapore 627833, Singapore
    Nanotechnology 25:105102. 2014
    ..This study concludes that gel formulation of imidazole drug-loaded SLNs and NLCs can be used for sustained/prolonged topical delivery of the drugs. ..
  17. doi Increased ERK activation and cellular drug accumulation in the enhanced cytotoxicity of folate receptor-targeted liposomal carboplatin
    Anumita Chaudhury
    Department of Pharmacy, National University of Singapore, Singapore
    Int J Oncol 40:703-10. 2012
    ..Collectively, the current study suggests a novel mechanism by which FRT liposomes could sensitize cancer cells to drug treatment via modulation of ERK-related cell survival signals...
  18. doi The impact of aqueous solubility and dose on the pharmacokinetic profiles of resveratrol
    Surajit Das
    Department of Pharmacy, Faculty of Science, National University of Singapore, Building S4, Rm 05 02, 18 Science Drive 4, Singapore 117543, Singapore
    Pharm Res 25:2593-600. 2008
    ..This study aimed at the investigation of the impact of aqueous solubility and dose manipulation on the pharmacokinetics of resveratrol...