Atanu Singha Roy
Roy A, Samanta S, Ghosh P, Tripathy D, Ghosh S, Dasgupta S. Cell cytotoxicity and serum albumin binding capacity of the morin-Cu(ii) complex and its effect on deoxyribonucleic acid. Mol Biosyst. 2016;12:2818-33 pubmed publisher
..The results from binding studies confirmed that after complexation with the Cu(ii) ion, morin alters its mode of interaction with SAs which could have differential implications on its other biological and pharmaceutical properties. ..
Roy A, Tripathy D, Samanta S, Ghosh S, Dasgupta S. DNA damaging, cell cytotoxicity and serum albumin binding efficacy of the rutin-Cu(ii) complex. Mol Biosyst. 2016;12:1687-701 pubmed publisher
..33 kJ mol(-1) for HSA and BSA respectively) in the binding of rutin with SAs. It implies that after chelation with Cu(ii) ion, rutin alters its binding mode which could have varying applications to its other physicochemical activities...
Das S, Bora N, Rohman M, Sharma R, Jha A, Singha Roy A. Molecular recognition of bio-active flavonoids quercetin and rutin by bovine hemoglobin: an overview of the binding mechanism, thermodynamics and structural aspects through multi-spectroscopic and molecular dynamics simulation studies. Phys Chem Chem Phys. 2018;20:21668-21684 pubmed publisher
..Further investigations established that these flavonoids are efficient in the inhibition of glucose mediated glycation of BHb. ..