Fernando Moreira Simabuco
Tavares M, Pavan I, Amaral C, Meneguello L, Luchessi A, Simabuco F. The S6K protein family in health and disease. Life Sci. 2015;131:1-10 pubmed publisher
Amaral C, Freitas L, Tamura R, Tavares M, Pavan I, Bajgelman M, et al
. S6Ks isoforms contribute to viability, migration, docetaxel resistance and tumor formation of prostate cancer cells. BMC Cancer. 2016;16:602 pubmed publisher
..We also provide evidence that S6K1 inhibitor PF-4708671 may be considered as a potential drug for prostate cancer treatment. ..
Pavan I, Yokoo S, Granato D, Meneguello L, Carnielli C, Tavares M, et al
. Different interactomes for p70-S6K1 and p54-S6K2 revealed by proteomic analysis. Proteomics. 2016;16:2650-2666 pubmed publisher
..This study provides new information about the interacting networks of S6Ks, which may contribute for future approaches to a better understanding of the mTOR/S6K pathway. ..