The Perugia hospital-based Stroke Registry: report of the 2nd yearGiorgio Silvestrelli
Department of Neuroscience, University of Perugia, Italy
Clin Exp Hypertens 24:485-91. 2002
..5%. Overall hospital mortality was 10%. In cerebral hemorrhage mortality was 18% (44/240) vs. 6.3% (32/534) in ischemic stroke (p < 0.05). The distribution of stroke types and mortality was similar to other previous reports...
Gender differences in patients with acute ischemic strokeValeria Caso
Stroke Unit, Division of Cardiovascular Medicine, University of Perugia, Italy
Womens Health (Lond Engl) 6:51-7. 2010
..In addition, both genders demonstrated different stroke pathophysiologies. These findings should be taken into account when diagnostic workup and treatment are being planned...
- First-ever stroke and outcome in patients admitted to Perugia Stroke Unit: predictors for death, dependency, and recurrence of stroke within the first three months
Monica Acciarresi
Stroke Unit, Department of Neuroscience, University of Perugia, Perugia, Italy
Clin Exp Hypertens 28:287-94. 2006
..The best predictors for dependency after 3 months were age and stroke severity. The only variable identified as the best predictor for recurrence was the presence of diabetes mellitus...
- Acute hyperglycemia and early hemorrhagic transformation in ischemic stroke
Maurizio Paciaroni
Stroke Unit, University of Perugia, Perugia, Italy
Cerebrovasc Dis 28:119-23. 2009
..The aim of this study was to assess whether the admission blood glucose level is related to HT in a prospective study in consecutive patients with acute ischemic stroke...
- Effect of carotid stenosis on the prognostic value of admission blood pressure in patients with acute ischemic stroke
Maurizio Paciaroni
Stroke Unit, University of Perugia, Italy
Atherosclerosis 206:469-73. 2009
....
- Risk of recurrent cerebrovascular events in patients with cryptogenic stroke or transient ischemic attack and patent foramen ovale: the FORI (Foramen Ovale Registro Italiano) study
Maurizio Paciaroni
Stroke Unit, Division of Cardiovascular Medicine, University of Perugia, Perugia, Italy
Cerebrovasc Dis 31:109-16. 2011
....
- Outcome in patients with stroke associated with internal carotid artery occlusion
Maurizio Paciaroni
Stroke Unit, Department of Neuroscience, University of Perugia, Ospedale Silvestrini, Perugia, Italy
Cerebrovasc Dis 20:108-13. 2005
..The purposes of this study were (1) to assess the predictive factors of adverse outcome in patients with stroke associated with an occlusion of the ICA and (2) to evaluate the rate of spontaneous recanalization of an occluded ICA...
- Systemic thrombolysis in patients with acute ischemic stroke and Internal Carotid ARtery Occlusion: the ICARO study
Maurizio Paciaroni
Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, Santa Maria della Misericordia Hospital, Perugia 06126, Italy
Stroke 43:125-30. 2012
..The aim of this study was to evaluate the efficacy and safety of intravenous recombinant tissue-type plasminogen activator in these patients...
- Risk factors for cerebral ischemic events in patients with atrial fibrillation on warfarin for stroke prevention
Maurizio Paciaroni
Stroke Unit, Division of Cardiovascular Medicine, University of Perugia, UO Gravi Cerebrolesioni, S Giovanni Battista Hospital, Foligno, Perugia, Italy
Atherosclerosis 212:564-6. 2010
..The aim of this study was to evaluate the risk factors for cerebral ischemic events in warfarin-treated AF patients with an International Normalized Ratios (INR) above 1.8 on admission...
- Characteristics of delayed admission to stroke unit
Giorgio Silvestrelli
Department of Neuroscience, University of Perugia, Perugia, Italy
Clin Exp Hypertens 28:405-11. 2006
..To increase the proportion of stroke patients arriving in the SU within 3 hr of symptom onset, it is necessary to improve public and general practitioner awareness of stroke through educational programs...
- Risk factors and stroke subtypes: results of five consecutive years of the Perugia Stroke Registry
Giorgio Silvestrelli
Stroke Unit, Department of Neuroscience, University of Perugia, Perugia, Italy
Clin Exp Hypertens 28:279-86. 2006
..3%; cigarette smoking in 21.6%. Different potentially modifiable risk factors profiles were identified for each ischemic subtype of stroke, while in hemorrhagic lobar stroke subtypes, only male gender was an independent risk factor...
- Arterial hypertension and cognitive dysfunction in physiologic and pathologic aging of the brain
Alessia Lanari
Section of Neurology, University of Perugia, Perugia, Italy
Am J Geriatr Cardiol 16:158-64. 2007
..Different and probably converging pathophysiologic mechanisms explain the role of arterial hypertension in causing cognitive dysfunction in pathologic aging of the brain, specifically, vascular dementia and Alzheimer's disease...
- Dysphagia following Stroke
Maurizio Paciaroni
Stroke Unit, Department of Neuroscience, University of Perugia, Perugia, Italy
Eur Neurol 51:162-7. 2004
..We aimed to study the prognosis of dysphagia (assessed clinically) over the first 3 months after acute stroke and to determine whether specific neurovascular-anatomical sites were associated with swallowing dysfunction...
- Efficacy of thrombolytic (rt-PA) therapy in old stroke patients: the Perugia Stroke Unit experience
Lucilla Parnetti
Stroke Unit, Department of Neuroscience, University of Perugia, Perugia, Italy
Clin Exp Hypertens 28:397-404. 2006
..Age did not influence prognosis in patients treated with rt-PA. The oldest stroke patients should not be excluded from rt-PA treatment on the basis of age per se...
- Treatment of Alzheimer's disease: from pharmacology to a better understanding of disease pathophysiology
Giorgio Silvestrelli
Section of Neurology, Department of Medical and Surgical Specialisties and Public Health, University of Perugia, Ospedale Silvestrini, 06156 Perugia, Italy
Mech Ageing Dev 127:148-57. 2006
..This paper reviews the main symptomatic strategies available for treating AD and future strategies for improving our therapeutic approach to AD...
- Effect of on-admission antiplatelet treatment on patients with cerebral hemorrhage
Valeria Caso
Stroke Unit, Ospedale Santa Maria della Misericordia, San Andrea delle Fratte, Perugia, Italy
Cerebrovasc Dis 24:215-8. 2007
..The aim of this study was to assess the influence of antiplatelet treatment on clinical outcome at hospital discharge...
Determinants of outcome in patients eligible for thrombolysis for ischemic strokeValeria Caso
Stroke Unit, Department of Internal Medicine, Ospedale Silvestrini Perugia, Italy
Vasc Health Risk Manag 3:749-54. 2007
..However, not all eligible patients benefit from this treatment. This study aimed to assess the determinants for clinical outcome in consecutive, eligible patients with ischemic stroke treated with thrombolysis in a single-center study...
- Intravenous thrombolysis for acute ischemic stroke associated to extracranial internal carotid artery occlusion: the ICARO-2 study
Maurizio Paciaroni
Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, Perugia, Italy
Cerebrovasc Dis 34:430-5. 2012
..The aim of this cohort study was to assess the efficacy and safety of thrombolysis in patients with eICA occlusion compared to those without eICA occlusion...
- Diagnosing prodromal Alzheimer's disease: role of CSF biochemical markers
Lucilla Parnetti
Section of Neurology, Department of Medical and Surgical Specialties and Public Health, University of Perugia, Ospedale Silvestrini, S Andrea delle Fratte, 06156 Perugia, Italy
Mech Ageing Dev 127:129-32. 2006
..On the contrary, 29 out of 33 stable MCI (88%) showed no or one pathological CSF value. We confirm that pathological levels in >or=2 CSF biomarkers reliably predict MCI conversion to AD and correctly identify the stable form of MCI...
- Early hemorrhagic transformation of brain infarction: rate, predictive factors, and influence on clinical outcome: results of a prospective multicenter study
Maurizio Paciaroni
Stroke Unit, Division of Cardiovascular Medicine, University of Perugia, Santa Maria della Misericordia Hospital, Sant Andrea delle Fratte, Perugia, 06126 Italy
Stroke 39:2249-56. 2008
..The aims of this study were to assess: (1) the rate of early HT in patients admitted for ischemic stroke, (2) the correlation between early HT and functional outcome at 3 months, and (3) the risk factors for early HT...
- Multimodal use of computed tomography in early acute stroke, part 1
Nicola Tambasco
Dipartimento di Neurologia e Neuroriabilitazione, Villa Pini d Abruzzo, Chieti, Italy
Clin Exp Hypertens 28:421-6. 2006
....
- Arterial hypertension and stroke prevention: an update
Natan Bornstein
Department of Neurology, Sourasky Medical Center, Tel Aviv, Israel
Clin Exp Hypertens 28:317-26. 2006
..than ACE-Is? Should ACE-Is and ARBs be considered routinely for either high-risk stroke patients or patients with history of stroke or transient ischemic attack, irrespective of blood pressure? What is the role of lifestyle in BP control?..
