H Sillesen

Summary

Publications

  1. ncbi request reprint Statins and their use in preventing carotid disease
    Henrik Sillesen
    Department of Vascular Surgery, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, DK 2100, Denmark
    Curr Atheroscler Rep 11:309-14. 2009
  2. doi request reprint Predicting coronary heart disease: from Framingham Risk Score to ultrasound bioimaging
    Henrik Sillesen
    Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Mt Sinai J Med 79:654-63. 2012
  3. pmc The high-risk plaque initiative: primary prevention of atherothrombotic events in the asymptomatic population
    Erling Falk
    Atherosclerosis Research Unit, Department of Cardiology Institute of Clinial Medicine, Aarhus University Hospital Skejby, Brendstrupgaardsvej 100, Aarhus, Denmark
    Curr Atheroscler Rep 13:359-66. 2011
  4. doi request reprint Atorvastatin reduces the risk of cardiovascular events in patients with carotid atherosclerosis: a secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial
    Henrik Sillesen
    Department of Vascular Surgery, Rigshospitalet, University of Copenhagen, Copenhagen O, Denmark
    Stroke 39:3297-302. 2008
  5. doi request reprint Peripheral artery disease (PAD) screening in the asymptomatic population: why, how, and who?
    Henrik Sillesen
    Department of Vascular Surgery, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Curr Atheroscler Rep 13:390-5. 2011
  6. doi request reprint World Federation of Vascular Societies: presidential address
    H Sillesen
    Department of Vascular Surgery, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, Copenhagen O, Denmark
    Eur J Vasc Endovasc Surg 39:S1-4. 2010
  7. ncbi request reprint Echo-lucency of computerized ultrasound images of carotid atherosclerotic plaques are associated with increased levels of triglyceride-rich lipoproteins as well as increased plaque lipid content
    M L Grønholdt
    Department of Vascular Surgery, Rigshospitalet, University Hospital of Copenhagen, Denmark
    Circulation 97:34-40. 1998
  8. ncbi request reprint Increased acute phase reactants are associated with levels of lipoproteins and increased carotid plaque volume
    M L Grønholdt
    Department of Vascular Surgery, RK 3112, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen Ø, Denmark
    Eur J Vasc Endovasc Surg 21:227-34. 2001
  9. ncbi request reprint Echolucent carotid artery plaques are associated with elevated levels of fasting and postprandial triglyceride-rich lipoproteins
    M L Grønholdt
    Department of Vascular Surgery, Rigshospitalet, Copenhagen, Denmark
    Stroke 27:2166-72. 1996
  10. doi request reprint Molecular pathology in vulnerable carotid plaques: correlation with [18]-fluorodeoxyglucose positron emission tomography (FDG-PET)
    M Graebe
    Department of Vascular Surgery, Rigshospitalet RK 3111, University of Copenhagen, Copenhagen E, Denmark
    Eur J Vasc Endovasc Surg 37:714-21. 2009

Detail Information

Publications22

  1. ncbi request reprint Statins and their use in preventing carotid disease
    Henrik Sillesen
    Department of Vascular Surgery, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, DK 2100, Denmark
    Curr Atheroscler Rep 11:309-14. 2009
    ..Finally, statins appear to reduce the risk of all cardiovascular events (eg, stroke, myocardial infarction, need for revascularization) in patients with carotid stenosis. This review summarizes and discusses the existing data...
  2. doi request reprint Predicting coronary heart disease: from Framingham Risk Score to ultrasound bioimaging
    Henrik Sillesen
    Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Mt Sinai J Med 79:654-63. 2012
    ..The High-Risk Plaque Initiative BioImage Study is currently investigating the predictive value of total carotid plaque volume with respect to prediction of future cardiovascular events...
  3. pmc The high-risk plaque initiative: primary prevention of atherothrombotic events in the asymptomatic population
    Erling Falk
    Atherosclerosis Research Unit, Department of Cardiology Institute of Clinial Medicine, Aarhus University Hospital Skejby, Brendstrupgaardsvej 100, Aarhus, Denmark
    Curr Atheroscler Rep 13:359-66. 2011
    ..Plasma, PAXgene RNA, and DNA samples were obtained for biomarker discovery studies. All individuals will be followed until 600 major atherothrombotic events have occurred in those undergoing imaging...
  4. doi request reprint Atorvastatin reduces the risk of cardiovascular events in patients with carotid atherosclerosis: a secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial
    Henrik Sillesen
    Department of Vascular Surgery, Rigshospitalet, University of Copenhagen, Copenhagen O, Denmark
    Stroke 39:3297-302. 2008
    ..We hypothesized this benefit would be greatest in the subgroup of patients with carotid stenosis...
  5. doi request reprint Peripheral artery disease (PAD) screening in the asymptomatic population: why, how, and who?
    Henrik Sillesen
    Department of Vascular Surgery, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Curr Atheroscler Rep 13:390-5. 2011
    ..Unfortunately, most primary care physicians are not performing ABI in their office. Reimbursement issues along with inadequate knowledge of ABI are barriers for adoption and must be addressed...
  6. doi request reprint World Federation of Vascular Societies: presidential address
    H Sillesen
    Department of Vascular Surgery, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, Copenhagen O, Denmark
    Eur J Vasc Endovasc Surg 39:S1-4. 2010
    ..The WFVS is important simply looking at the huge demographic differences throughout the world. In addition, for introduction of new treatments, training issues and dissemination of science a global organisation like the WFVS is needed...
  7. ncbi request reprint Echo-lucency of computerized ultrasound images of carotid atherosclerotic plaques are associated with increased levels of triglyceride-rich lipoproteins as well as increased plaque lipid content
    M L Grønholdt
    Department of Vascular Surgery, Rigshospitalet, University Hospital of Copenhagen, Denmark
    Circulation 97:34-40. 1998
    ..We tested the hypotheses that triglyceride-rich lipoproteins in the fasting and postprandial state predict carotid plaque echo-lucency and that echo-lucency predicts a high plaque lipid content...
  8. ncbi request reprint Increased acute phase reactants are associated with levels of lipoproteins and increased carotid plaque volume
    M L Grønholdt
    Department of Vascular Surgery, RK 3112, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen Ø, Denmark
    Eur J Vasc Endovasc Surg 21:227-34. 2001
    ..to test the hypotheses that increased acute phase reactants predict elevated levels of lipoproteins and increased plaque volume as well as echolucency of carotid plaques...
  9. ncbi request reprint Echolucent carotid artery plaques are associated with elevated levels of fasting and postprandial triglyceride-rich lipoproteins
    M L Grønholdt
    Department of Vascular Surgery, Rigshospitalet, Copenhagen, Denmark
    Stroke 27:2166-72. 1996
    ..Elevated plasma triglycerides is a risk factor for cerebral and coronary infarction. This study examined these individual pathogenetic risk factors to determine whether they were related...
  10. doi request reprint Molecular pathology in vulnerable carotid plaques: correlation with [18]-fluorodeoxyglucose positron emission tomography (FDG-PET)
    M Graebe
    Department of Vascular Surgery, Rigshospitalet RK 3111, University of Copenhagen, Copenhagen E, Denmark
    Eur J Vasc Endovasc Surg 37:714-21. 2009
    ..Uptake was correlated to quantitative gene expression of known markers of inflammation and plaque vulnerability...
  11. ncbi request reprint What does 'best medical therapy' really mean?
    H Sillesen
    Department of Vascular Surgery, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen O, Denmark
    Eur J Vasc Endovasc Surg 35:139-44. 2008
    ..This article reviews the evidence that is available concerning medical therapy for patients with carotid stenosis, with special emphasis on antiplatelet and statin therapy. An example on how this treatment may be organised is given...
  12. ncbi request reprint Real-time spatial compound imaging improves reproducibility in the evaluation of atherosclerotic carotid plaques
    S C Kofoed
    Department of Vascular Surgery, Gentofte University Hospital, DK 2900 Hellerup, Copenhagen, Denmark
    Ultrasound Med Biol 27:1311-7. 2001
    ..In conclusion, compound imaging improves intra- and interobserver agreement and reduces interobserver variation in the GSM value in a clinical setting...
  13. doi request reprint Outcome and survival of patients aged 75 years and older compared to younger patients after ruptured abdominal aortic aneurysm repair: do the results justify the effort?
    S Shahidi
    Department of Vascular Surgery, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark
    Ann Vasc Surg 23:469-77. 2009
    ..In our experience, surgical open repair has been life-saving in 33% of patients aged 75 years and older, at a relatively low price for each life, estimated at euro 40,409...
  14. ncbi request reprint Organising a nurse-driven PAD rehabilitation clinic within the vascular surgical department: what is required and are treatment goals reached--a prospective study?
    H Sillesen
    Department of Vascular Surgery, Rigshospitalet, Denmark
    Eur J Vasc Endovasc Surg 33:26-32. 2007
    ..The purpose of this study was to identify whether treatment goals of a nurse led rehabilitation clinic were achieved...
  15. ncbi request reprint Spiral computed tomographic imaging related to computerized ultrasonographic images of carotid plaque morphology and histology
    M L Grønholdt
    Department of Vascular Surgery, Rigshospitalet, Copenhagen, Denmark
    J Ultrasound Med 20:451-8. 2001
    ....
  16. doi request reprint Comparison of ankle-brachial index measured by an automated oscillometric apparatus with that by standard Doppler technique in vascular patients
    M Kornø
    Department of Vascular Surgery, Rigshospitalet, University of Copenhagen, Denmark
    Eur J Vasc Endovasc Surg 38:610-5. 2009
    ..To evaluate the determination of ankle-brachial indices (ABIs) using a simple automated ankle pressure measurement device in comparison with the Doppler technique...
  17. doi request reprint Volume estimation of the aortic sac after EVAR using 3-D ultrasound - a novel, accurate and promising technique
    K Bredahl
    Department of Vascular Surgery, University Hospital of Copenhagen, Denmark
    Eur J Vasc Endovasc Surg 45:450-5; discussin 456. 2013
    ..The potential of 3-D ultrasound (3-D US) for volume estimation in EVAR surveillance is unknown...
  18. doi request reprint Reproducibility of ECG-gated ultrasound diameter assessment of small abdominal aortic aneurysms
    K Bredahl
    Department of Interventional Radiology, University Hospital of Copenhagen, Copenhagen, Denmark
    Eur J Vasc Endovasc Surg 45:235-40. 2013
    ..We investigated the feasibility and reproducibility of a novel approach controlling for a combination of vessel wall delineation and cardiac cycle variation...
  19. ncbi request reprint Fibrinogen predicts ischaemic stroke and advanced atherosclerosis but not echolucent, rupture-prone carotid plaques: the Copenhagen City Heart Study
    S C Kofoed
    Department of Vascular Surgery, Gentofte University Hospital, Denmark
    Eur Heart J 24:567-76. 2003
    ..We examined whether fibrinogen predicts incidence of ischaemic stroke, advanced atherosclerosis (measured as carotid artery stenosis) and/or echolucent, rupture-prone plaques...
  20. ncbi request reprint Conservative treatment, amputation or revascularisation for critical limb ischaemia
    H Sillesen
    Department of Vascular Surgery B, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
    Ann Chir Gynaecol 87:159-61. 1998
    ....
  21. ncbi request reprint The use of intravascular ultrasound for intraoperative assessment during semiclosed thromboendarterectomy
    K C Vogt
    Department of Vascular Surgery, Rigshospitalet, University of Copenhagen, Denmark
    Ultrasound Med Biol 24:21-5. 1998
    ..We conclude that IVUS is a feasible method for intraoperative assessment of semiclosed TEA. The rate of early failures due to residual material might be reduced by this new application of IVUS...
  22. doi request reprint Observer agreement of lower limb venous reflux assessed by duplex ultrasound scanning using manual and pneumatic cuff compression in patients with chronic venous disease and controls
    R Broholm
    Vascular Clinic, Department of Vascular Surgery, Rigshospitalet and Gentofte, University of Copenhagen, Copenhagen, Denmark
    Eur J Vasc Endovasc Surg 41:704-10. 2011
    ..In addition, the two methods were compared with each other with regard to immediate "eyeballing" and direct measurements of reflux time from Doppler flow curves...