Inge Sillaber

Summary

Publications

  1. doi request reprint Profiling of behavioral changes and hippocampal gene expression in mice chronically treated with the SSRI paroxetine
    Inge Sillaber
    Max Planck Institute of Psychiatry, 80804 Munich, Germany
    Psychopharmacology (Berl) 200:557-72. 2008
  2. ncbi request reprint The temporal dynamics of intrahippocampal corticosterone in response to stress-related stimuli with different emotional and physical load: an in vivo microdialysis study in C57BL/6 and DBA/2 inbred mice
    Christoph K Thoeringer
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Psychoneuroendocrinology 32:746-57. 2007
  3. pmc Gene expression profiling in the stress control brain region hypothalamic paraventricular nucleus reveals a novel gene network including amyloid beta precursor protein
    Amalia Tsolakidou
    Max Planck Institute of Psychiatry, Munich, Germany
    BMC Genomics 11:546. 2010
  4. ncbi request reprint Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress
    Marianne B Muller
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, Munich 80804, Germany
    Nat Neurosci 6:1100-7. 2003
  5. ncbi request reprint Stress and alcohol drinking
    Inge Sillaber
    Max Planck Institute of Psychiatry, Munich, Germany
    Ann Med 36:596-605. 2004
  6. doi request reprint Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1
    Damian Refojo
    Max Planck Institute of Psychiatry, Munich, Germany
    Science 333:1903-7. 2011
  7. ncbi request reprint Identification of molecules potentially involved in mediating the in vivo actions of the corticotropin-releasing hormone receptor 1 antagonist, NBI30775 (R121919)
    Anke Post
    Max Planck Institute of Psychiatry, Kraepelinstrasse 10, 80804 Munich, Germany
    Psychopharmacology (Berl) 180:150-8. 2005
  8. ncbi request reprint Proteomic and metabolomic profiling reveals time-dependent changes in hippocampal metabolism upon paroxetine treatment and biomarker candidates
    Christian Webhofer
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany Graduate School of Systemic Neurosciences, Ludwig Maximilians University Munich, Planegg Martinsried, Germany
    J Psychiatr Res 47:289-98. 2013
  9. ncbi request reprint Location and size of dopaminergic and serotonergic cell populations are controlled by the position of the midbrain-hindbrain organizer
    Claude Brodski
    Max Planck Institute of Psychiatry, 80804 Munich, Germany, and GSF National Research Center for Environment and Health, Technical University Munich, Institute of Developmental Genetics, 85758 Oberschleissheim, Germany
    J Neurosci 23:4199-207. 2003
  10. ncbi request reprint P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder
    Susanne Lucae
    The Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Hum Mol Genet 15:2438-45. 2006

Collaborators

Detail Information

Publications11

  1. doi request reprint Profiling of behavioral changes and hippocampal gene expression in mice chronically treated with the SSRI paroxetine
    Inge Sillaber
    Max Planck Institute of Psychiatry, 80804 Munich, Germany
    Psychopharmacology (Berl) 200:557-72. 2008
    ..Monoamine-based antidepressants inhibit neurotransmitter reuptake within short time. However, it commonly takes several weeks until clinical symptoms start to resolve--indicating the involvement of effects distant from reuptake inhibition...
  2. ncbi request reprint The temporal dynamics of intrahippocampal corticosterone in response to stress-related stimuli with different emotional and physical load: an in vivo microdialysis study in C57BL/6 and DBA/2 inbred mice
    Christoph K Thoeringer
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Psychoneuroendocrinology 32:746-57. 2007
    ..In addition, our study highlights the use of in vivo microdialysis to assess the neuroendocrine endophenotype of animal models via profiling of stimulus-response patterns of stress hormones...
  3. pmc Gene expression profiling in the stress control brain region hypothalamic paraventricular nucleus reveals a novel gene network including amyloid beta precursor protein
    Amalia Tsolakidou
    Max Planck Institute of Psychiatry, Munich, Germany
    BMC Genomics 11:546. 2010
    ..Gene expression and regulation was determined by microarray analyses and further evaluated by bioinformatics tools including pathway and cluster analyses...
  4. ncbi request reprint Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress
    Marianne B Muller
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, Munich 80804, Germany
    Nat Neurosci 6:1100-7. 2003
    ..Furthermore, we provide evidence for a new role of limbic Crhr1 in neuroendocrine adaptation to stress...
  5. ncbi request reprint Stress and alcohol drinking
    Inge Sillaber
    Max Planck Institute of Psychiatry, Munich, Germany
    Ann Med 36:596-605. 2004
    ..Individuals with a dysfunctional HPA axis, inherited and/or acquired, might represent such a subgroup of stress-motivated drinkers...
  6. doi request reprint Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1
    Damian Refojo
    Max Planck Institute of Psychiatry, Munich, Germany
    Science 333:1903-7. 2011
    ..These results define a bidirectional model for the role of CRHR1 in anxiety and suggest that an imbalance between CRHR1-controlled anxiogenic glutamatergic and anxiolytic dopaminergic systems might lead to emotional disorders...
  7. ncbi request reprint Identification of molecules potentially involved in mediating the in vivo actions of the corticotropin-releasing hormone receptor 1 antagonist, NBI30775 (R121919)
    Anke Post
    Max Planck Institute of Psychiatry, Kraepelinstrasse 10, 80804 Munich, Germany
    Psychopharmacology (Berl) 180:150-8. 2005
    ..Despite its therapeutic efficacy, there is only little information about its mechanisms of action on cellular and molecular targets...
  8. ncbi request reprint Proteomic and metabolomic profiling reveals time-dependent changes in hippocampal metabolism upon paroxetine treatment and biomarker candidates
    Christian Webhofer
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany Graduate School of Systemic Neurosciences, Ludwig Maximilians University Munich, Planegg Martinsried, Germany
    J Psychiatr Res 47:289-98. 2013
    ....
  9. ncbi request reprint Location and size of dopaminergic and serotonergic cell populations are controlled by the position of the midbrain-hindbrain organizer
    Claude Brodski
    Max Planck Institute of Psychiatry, 80804 Munich, Germany, and GSF National Research Center for Environment and Health, Technical University Munich, Institute of Developmental Genetics, 85758 Oberschleissheim, Germany
    J Neurosci 23:4199-207. 2003
    ..In addition, our data suggest that the position of the MHO during embryogenesis can modulate adult locomotor activity...
  10. ncbi request reprint P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder
    Susanne Lucae
    The Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Hum Mol Genet 15:2438-45. 2006
    ..This polymorphism results in an amino acid exchange in the C-terminal cytosolic domain of the P2RX7 channel protein, suggesting that the observed P2RX7 polymorphism might play a causal role in the development of depression...
  11. ncbi request reprint Enhanced and delayed stress-induced alcohol drinking in mice lacking functional CRH1 receptors
    Inge Sillaber
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Science 296:931-3. 2002
    ..Alterations in the CRH1 receptor gene and adaptional changes in NR2B subunits may constitute a genetic risk factor for stress-induced alcohol drinking and alcoholism...