David L Silver



  1. Harel T, Quek D, Wong B, Cazenave Gassiot A, Wenk M, Fan H, et al. Homozygous mutation in MFSD2A, encoding a lysolipid transporter for docosahexanoic acid, is associated with microcephaly and hypomyelination. Neurogenetics. 2018;19:227-235 pubmed publisher
  2. Tan J, Seow C, Goh V, Silver D. Recent advances in understanding proteins involved in lipid droplet formation, growth and fusion. J Genet Genomics. 2014;41:251-9 pubmed publisher
    ..Finally, we present important challenges in LD biology for a deeper understanding of this dynamic organelle to be achieved. ..
  3. Goh V, Tan J, Tan B, Seow C, Ong W, Lim Y, et al. Postnatal Deletion of Fat Storage-inducing Transmembrane Protein 2 (FIT2/FITM2) Causes Lethal Enteropathy. J Biol Chem. 2015;290:25686-99 pubmed publisher
    ..These data support the conclusion that FIT2 plays an essential role in regulating intestinal health and survival postnatally. ..
  4. Quek D, Nguyen L, Fan H, Silver D. Structural Insights into the Transport Mechanism of the Human Sodium-dependent Lysophosphatidylcholine Transporter MFSD2A. J Biol Chem. 2016;291:9383-94 pubmed publisher
  5. Wong B, Chan J, Cazenave Gassiot A, Poh R, Foo J, Galam D, et al. Mfsd2a Is a Transporter for the Essential ω-3 Fatty Acid Docosahexaenoic Acid (DHA) in Eye and Is Important for Photoreceptor Cell Development. J Biol Chem. 2016;291:10501-14 pubmed publisher
    ..These findings identify LPC transport via Mfsd2a as an important pathway for DHA uptake in eye and for development of photoreceptor membrane discs. ..