Yatin J Shukla

Summary

Publications

  1. doi request reprint Pregnane glycosides from Hoodia gordonii
    Yatin J Shukla
    Department of Pharmacognosy, School of Pharmacy, University of Mississippi, MS 38677, USA
    Phytochemistry 70:675-83. 2009
  2. doi request reprint A rapid method for chemical fingerprint analysis of Hoodia species, related genera, and dietary supplements using UPLC-UV-MS
    Bharathi Avula
    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, The University of Mississippi, University, MS 38677, USA
    J Pharm Biomed Anal 48:722-31. 2008
  3. doi request reprint Chemical fingerprint of Hoodia species, dietary supplements, and related genera by using HPTLC
    Chidananda Swamy Rumalla
    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, The University of Mississippi, University, MS 38677, USA
    J Sep Sci 31:3959-64. 2008
  4. doi request reprint Characterization of in vitro pharmacokinetic properties of hoodigogenin A from Hoodia gordonii
    Vamsi Lakshmi Madgula
    National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS 38677, USA
    Planta Med 76:62-9. 2010
  5. ncbi request reprint Quantitative determination of pregnanes from aerial parts of Caralluma species using HPLC-UV and identification by LC-ESI-TOF
    Bharathi Avula
    The University of Mississippi, School of Pharmacy, National Center for Natural Products Research, University, MS 38677, USA
    J AOAC Int 94:1383-90. 2011
  6. ncbi request reprint New oxypregnane glycosides from appetite suppressant herbal supplement Hoodia gordonii
    Rahul S Pawar
    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, University, MS 38677, USA
    Steroids 72:524-34. 2007
  7. ncbi request reprint Chemical fingerprinting of Hoodia species and related genera: chemical analysis of oxypregnane glycosides using high-performance liquid chromatography with UV detection in Hoodia gordonii
    Bharathi Avula
    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, The University of Mississippi, University, MS 38677, USA
    J AOAC Int 90:1526-31. 2007
  8. doi request reprint In vitro metabolic stability and intestinal transport of P57AS3 (P57) from Hoodia gordonii and its interaction with drug metabolizing enzymes
    Vamsi L M Madgula
    National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS, USA
    Planta Med 74:1269-75. 2008
  9. ncbi request reprint New calogenin glycosides from Hoodia gordonii
    Rahul S Pawar
    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, University, MS 38677, USA
    Steroids 72:881-91. 2007
  10. ncbi request reprint Determination of the appetite suppressant P57 in Hoodia gordonii plant extracts and dietary supplements by liquid chromatography/electrospray ionization mass spectrometry (LC-MSD-TOF) and LC-UV methods
    Bharathi Avula
    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, The University of Mississippi, MS 38677, USA
    J AOAC Int 89:606-11. 2006

Collaborators

Detail Information

Publications10

  1. doi request reprint Pregnane glycosides from Hoodia gordonii
    Yatin J Shukla
    Department of Pharmacognosy, School of Pharmacy, University of Mississippi, MS 38677, USA
    Phytochemistry 70:675-83. 2009
    ..Their structures were elucidated by chemical degradation studies and spectroscopic methods, including 1D and 2D NMR and CD spectroscopic methods...
  2. doi request reprint A rapid method for chemical fingerprint analysis of Hoodia species, related genera, and dietary supplements using UPLC-UV-MS
    Bharathi Avula
    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, The University of Mississippi, University, MS 38677, USA
    J Pharm Biomed Anal 48:722-31. 2008
    ..Different sample matrices were successfully analyzed, providing the wide range of applicability of this method, including gels, capsules, tablets, sprays, tea bags, snack bars, powders and juices...
  3. doi request reprint Chemical fingerprint of Hoodia species, dietary supplements, and related genera by using HPTLC
    Chidananda Swamy Rumalla
    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, The University of Mississippi, University, MS 38677, USA
    J Sep Sci 31:3959-64. 2008
    ..The developed method was validated for specificity, stability, repeatability, and robustness. The results of HPTLC method were verified by LC-UV-MS method...
  4. doi request reprint Characterization of in vitro pharmacokinetic properties of hoodigogenin A from Hoodia gordonii
    Vamsi Lakshmi Madgula
    National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS 38677, USA
    Planta Med 76:62-9. 2010
    ..The compound strongly inhibited CYP3A4 activity (IC(50) 3 microM), indicating a possibility of drug-herb/botanical interactions when products containing H. gordonii are used simultaneously with other botanicals/herbs/drugs...
  5. ncbi request reprint Quantitative determination of pregnanes from aerial parts of Caralluma species using HPLC-UV and identification by LC-ESI-TOF
    Bharathi Avula
    The University of Mississippi, School of Pharmacy, National Center for Natural Products Research, University, MS 38677, USA
    J AOAC Int 94:1383-90. 2011
    ..fimbriata. An LCIMS coupled with electrospray ionization interface method was used for the identification of compounds and involved the use of [M+Na]+ ions in the positive ion mode with extracted ion chromatogram...
  6. ncbi request reprint New oxypregnane glycosides from appetite suppressant herbal supplement Hoodia gordonii
    Rahul S Pawar
    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, University, MS 38677, USA
    Steroids 72:524-34. 2007
    ..Cytotoxicity and antioxidant activities of these compounds were tested in cell based assays where they were found to be inactive...
  7. ncbi request reprint Chemical fingerprinting of Hoodia species and related genera: chemical analysis of oxypregnane glycosides using high-performance liquid chromatography with UV detection in Hoodia gordonii
    Bharathi Avula
    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, The University of Mississippi, University, MS 38677, USA
    J AOAC Int 90:1526-31. 2007
    ..The developed method was applied to the identification of oxypregnane glycosides in 3 different species of Hoodia and 23 related genera. The HPLC profiles of various plant samples were compared for the presence of oxypregnane glycosides...
  8. doi request reprint In vitro metabolic stability and intestinal transport of P57AS3 (P57) from Hoodia gordonii and its interaction with drug metabolizing enzymes
    Vamsi L M Madgula
    National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS, USA
    Planta Med 74:1269-75. 2008
    ..In conclusion, intestinal transport of P57 was mediated by P-gp and MRP transporters. The compound was metabolically stable and showed weak inhibition of CYP 3A4...
  9. ncbi request reprint New calogenin glycosides from Hoodia gordonii
    Rahul S Pawar
    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, University, MS 38677, USA
    Steroids 72:881-91. 2007
    ..The structures of the glycosides were established by chemical degradation studies and extensive spectroscopic techniques that included one-dimensional and two-dimensional NMR...
  10. ncbi request reprint Determination of the appetite suppressant P57 in Hoodia gordonii plant extracts and dietary supplements by liquid chromatography/electrospray ionization mass spectrometry (LC-MSD-TOF) and LC-UV methods
    Bharathi Avula
    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, The University of Mississippi, MS 38677, USA
    J AOAC Int 89:606-11. 2006
    ..0%) and recovery (98.5-103.5%). The developed methods were applied to the determination of P57 for H. gordonii plant samples, one related genus (Opuntia ficus-indica), and dietary supplements that claim to contain H. gordonii...