Renal artery stenting: indications, techniques, and devicesP A Erwin
Cardiovascular Institute Mount Sinai School of Medicine New York, NY, USA
Minerva Cardioangiol 61:189-99. 2013
..The role of drug eluting stents is examined, as are approaches to the detection and treatment of in-stent restenosis...
- Inflammation: implications for understanding the heart-brain connection
Mehdi H Shishehbor
Department of Cardiovascular Medicine, Cleveland Clinic Cleveland, OH 44195, USA
Cleve Clin J Med 74:S37-41. 2007
- High-density lipoprotein as a therapeutic target: a systematic review
Inder M Singh
Department of Cardiovascular Medicine, Krannert Institute of Cardiology, Indiana University Medical Center, Indianapolis, USA
JAMA 298:786-98. 2007
..High-density lipoprotein cholesterol (HDL-C) is a cardiovascular risk factor that is gaining substantial interest as a therapeutic target...
Association of neighborhood socioeconomic status with physical fitness in healthy young adults: the Coronary Artery Risk Development in Young Adults (CARDIA) studyMehdi H Shishehbor
Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Am Heart J 155:699-705. 2008
..The aim of the study was to examine the extent to which neighborhood socioeconomic status (SES) is associated with impaired fitness, independent of clinical characteristics and individual-level SES...
Emerging cardiovascular risk factors that account for a significant portion of attributable mortality risk in chronic kidney diseaseMehdi H Shishehbor
Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA
Am J Cardiol 101:1741-6. 2008
..5 micromol/L (the top tertile) were associated with a sevenfold greater mortality risk. In conclusion, homocysteine and fibrinogen levels explain nearly 40% of the attributable mortality risk from CKD...
- Impact of blood transfusion on short- and long-term mortality in patients with ST-segment elevation myocardial infarction
Mehdi H Shishehbor
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio 44195, USA
JACC Cardiovasc Interv 2:46-53. 2009
..We sought to examine the short- and long-term outcomes of blood transfusion in patients presenting with ST-segment elevation myocardial infarction (STEMI)...
- Impact of drug-eluting versus bare-metal stents on mortality in patients with anemia
Mehdi H Shishehbor
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio 44195 0002, USA
JACC Cardiovasc Interv 2:329-36. 2009
..Our aim was to assess the incidence of all-cause mortality in patients with anemia undergoing percutaneous coronary intervention (PCI) receiving drug-eluting stents (DES) or bare-metal stents (BMS)...
- Management of carotid disease in patients undergoing coronary artery bypass surgery: is it time to change our approach?
Sridhar Venkatachalam
Department of Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
Curr Opin Cardiol 26:480-7. 2011
..This review aims to compile current evidence in this area to help plan strategies for the optimal management of coexisting severe carotid and coronary disease...
- Comparison of drug-eluting stents versus bare-metal stents for treating ST-segment elevation myocardial infarction
Mehdi H Shishehbor
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA
JACC Cardiovasc Interv 1:227-32. 2008
..We sought to examine the clinical outcomes of patients treated with drug-eluting stents (DES) compared with bare-metal stents (BMS) during primary angioplasty for ST-segment elevation myocardial infarction (STEMI)...
- Drug-eluting stents versus bare-metal stents for treatment of bare-metal in-stent restenosis
Inder M Singh
Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Catheter Cardiovasc Interv 76:257-62. 2010
..We compared the long-term outcomes of drug-eluting stents (DES) versus bare-metal stents (BMS) for treatment of bare-metal in-stent restenosis (ISR)...
- Statins promote potent systemic antioxidant effects through specific inflammatory pathways
Mehdi H Shishehbor
Department of Cell Biology, and Center for Cardiovascular Diagnostics and Prevention, Cleveland Clinic Foundation, 9500 Euclid Ave, NC10, Cleveland, Ohio 44195, USA
Circulation 108:426-31. 2003
..The present results suggest potential mechanisms that may contribute to the beneficial actions of statins. They also have important implications for monitoring the antiinflammatory and antioxidant actions of these agents...
- Long-term impact of drug-eluting stents versus bare-metal stents on all-cause mortality
Mehdi H Shishehbor
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio 44195, USA
J Am Coll Cardiol 52:1041-8. 2008
..Our purpose was to examine the incidence of all-cause mortality among drug-eluting stents (DES) and bare-metal stents (BMS) while adjusting for many confounding factors generally not considered in prior studies...
- Enhanced prediction of mortality after percutaneous coronary intervention by consideration of general and neurological indicators
Stephen G Ellis
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio 44195, USA
JACC Cardiovasc Interv 4:442-8. 2011
..This study sought to improve methodology for predicting post-percutaneous coronary intervention (PCI) mortality...
- Safety and efficacy of carotid stenting in individuals with concomitant severe carotid and aortic stenosis
Subrata Kar
Department of Internal Medicine, Cleveland Clinic, Ohio, USA
EuroIntervention 6:492-7. 2010
..Carotid artery stenting (CAS) prior to open-heart surgery may be a useful approach to minimise the risk of neurologic events in patients undergoing aortic valve replacement (AVR)...
- In unstable angina or non-ST-segment acute coronary syndrome, should patients with multivessel coronary artery disease undergo multivessel or culprit-only stenting?
Mehdi H Shishehbor
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA
J Am Coll Cardiol 49:849-54. 2007
....
- Outcomes of cardiac catheterization and percutaneous coronary intervention for in-hospital ventricular tachycardia or fibrillation cardiac arrest
Thomas J Helton
Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
Catheter Cardiovasc Interv 80:E9-14. 2012
....
- Influence of gender on long-term mortality in patients presenting with non-ST-elevation acute coronary syndromes undergoing percutaneous coronary intervention
Dharam J Kumbhani
Department of Cardiovascular Medicine, Cleveland Clinic, Ohio, USA
Am J Cardiol 109:1087-91. 2012
..007). In conclusion, although overall mortality rates are similar between men and women undergoing PCI for NSTE-ACS, women <60 years old with negative biomarkers have a higher mortality than their men peers...
- Prognostic value of myeloperoxidase in patients with chest pain
Marie-Luise Brennan
Department of Cell Biology, Cleveland Clinic Foundation, Cleveland 44195, USA
N Engl J Med 349:1595-604. 2003
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- Association of socioeconomic status with functional capacity, heart rate recovery, and all-cause mortality
Mehdi H Shishehbor
Department of Cardiovascular Medicine, The Cleveland Clinic, Cleveland, Ohio 44195, USA
JAMA 295:784-92. 2006
..Lower socioeconomic status (SES) confers heightened cardiovascular risk and mortality, although the mediating pathways are unclear...
- Percutaneous treatment of aortic valve stenosis
Inder M Singh
Department of Cardiovascular Medicine, Cleveland Clinic Foundation, OH 44195, USA
Cleve Clin J Med 75:805-12. 2008
..Technical and device issues are being refined, and percutaneous aortic valve replacement is showing promise in ongoing clinical trials...
- Systemic elevations of free radical oxidation products of arachidonic acid are associated with angiographic evidence of coronary artery disease
Mehdi H Shishehbor
Department of Cell Biology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Free Radic Biol Med 41:1678-83. 2006
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- Clinical outcomes of drug-eluting versus bare-metal in-stent restenosis
Inder M Singh
Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
Catheter Cardiovasc Interv 75:338-42. 2010
..28) were also not different. This study represents the largest analysis comparing drug-eluting to bare-metal ISR. On multivariable Cox proportional hazard analyses, drug-eluting and bare-metal ISR have similar long term outcomes...
- Using statins to treat inflammation in acute coronary syndromes: Are we there yet?
Mehdi H Shishehbor
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Cleve Clin J Med 73:760-6. 2006
..In all the studies, the benefit correlated with reductions in CRP...
- Predictive value of renal resistive index in percutaneous renal interventions for atherosclerotic renal artery stenosis
Uygar C Yuksel
Sones Cardiac Catheterization Lab, Cleveland Clinic, Cleveland, OH, USA
J Invasive Cardiol 24:504-9. 2012
..In this study, the predictive value of renal resistive index (RRI) was retrospectively analyzed in identifying the patients who may benefit from renal angioplasty and stenting...
- Technique and outcome of ostial common carotid artery stenting: a single centre experience
Akin Cam
Department of Internal Medicine, Cleveland Clinic, Cleveland, OH, USA
EuroIntervention 7:1210-5. 2012
..Our aim was to report techniques and outcomes of our experience in percutaneous stenting of ostial common carotid artery lesions...
- Drug-eluting versus bare-metal stents for treating saphenous vein grafts
Mehdi H Shishehbor
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44114, USA
Am Heart J 158:637-43. 2009
..Current data show conflicting results regarding safety and efficacy of drug-eluting stents (DES) versus bare-metal stents (BMS) for treating saphenous vein grafts (SVG). Our objective was to compare DES with BMS for SVG intervention...
- Socioeconomic position, not race, is linked to death after cardiac surgery
Colleen G Koch
Department of Cardiothoracic Anesthesia, The Cleveland Clinic, Ohio 44195, USA
Circ Cardiovasc Qual Outcomes 3:267-76. 2010
..However, there is a complex interplay between race, sex, and socioeconomic position (SEP). In our investigation we sought to identify which of these was the driver of risk-adjusted survival...
- Inflammatory and oxidative markers in atherosclerosis: relationship to outcome
Mehdi H Shishehbor
Department of Preventive Cardiology, Cleveland Clinic Foundation, 9500 Euclid Avenue, C51, Cleveland, OH 44195, USA
Curr Atheroscler Rep 6:243-50. 2004
....
- Basic data related to endovascular management of peripheral arterial disease in critical limb ischemia
Sridhar Venkatachalam
Department of Medicine, Cleveland Clinic, Cleveland, OH, USA
Ann Vasc Surg 26:1039-51. 2012
..Such evolution makes data comparison difficult. This review aims to present the available data on endovascular therapy in critical limb ischemia patients reported over the past 2 decades...
- Percutaneous coronary revascularization in coronary artery disease: lessons from a single center experience
Olcay Aksoy
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio 44195, USA
Catheter Cardiovasc Interv 81:E1-8. 2013
..To determine the role of percutaneous coronary intervention (PCI) and its impact on mortality in coronary artery disease (CAD)...
- The association between early ventricular arrhythmias, renin-angiotensin-aldosterone system antagonism, and mortality in patients with ST-segment-elevation myocardial infarction: Insights from Global Use of Strategies to Open coronary arteries (GUSTO) V
Arman T Askari
Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA
Am Heart J 158:238-43. 2009
..Emerging data suggest that some of the benefit of renin-angiotensin-aldosterone system (RAAS) antagonism may be derived from a reduction in the incidence of these arrhythmias in the setting of acute myocardial infarction...
- Comparison of outcomes in patients undergoing coronary bypass of patent versus restenosed bare metal stented coronary arteries
Mehdi H Shishehbor
Department of Cardiology, Cleveland Clinic Foundation, Cleveland, Ohio, USA
Am J Cardiol 96:1416-9. 2005
..In conclusion, survival after bypassing a patent stented coronary artery is comparable to that after bypassing a stented restenotic coronary artery...
- Using C-reactive protein to assess cardiovascular disease risk
Mehdi H Shishehbor
Department of Internal Medicine, The Cleveland Clinic Foundation, OH 44195, USA
Cleve Clin J Med 70:634-40. 2003
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- Characterization and outcome of patients with severe symptomatic aortic stenosis referred for percutaneous aortic valve replacement
Samir R Kapadia
Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
J Thorac Cardiovasc Surg 137:1430-5. 2009
..We sought to define the characteristics and outcomes of patients referred for percutaneous aortic valve replacement...
- Morphology of the patent foramen ovale in asymptomatic versus symptomatic (stroke or transient ischemic attack) patients
Sachin S Goel
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA
Am J Cardiol 103:124-9. 2009
..In conclusion, PFOs in patients with cryptogenic CVAs are larger, have longer tunnels, and are more frequently associated with atrial septal aneurysms. This information should be considered when evaluating patients with cryptogenic CVAs...
- Downstream coronary effects of drug-eluting stents
Richard A Krasuski
Department of Cardiovascular Medicine, The Cleveland Clinic, OH 44195, USA
Am Heart J 162:764-771.e1. 2011
..We sought to compare the development of de novo stenoses and need for treatment in the downstream coronary vessel of patients treated with DES or a bare-metal stent...
- Outcome of multivessel coronary intervention in the contemporary percutaneous revascularization era
Mehdi H Shishehbor
Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA
Am J Cardiol 97:1585-90. 2006
..A randomized trial comparing multivessel PCI with staged or surgical revascularization is warranted...
- Carotid stenting vs surgery: parsing the risk of stroke and MI
Olcay Aksoy
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
Cleve Clin J Med 77:892-902. 2010
..Importantly, the risk of major stroke was low with either intervention. However, the results need to be considered in the context of the impact of each procedure on stroke and MI...
- Contemporary management of concomitant carotid and coronary artery disease
Sridhar Venkatachalam
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
Heart 97:175-80. 2011
..This review examines the available data on carotid revascularisation in relation to CABG surgery to aid in the risk-benefit decision analysis in this controversial area...
- Association of triglyceride-to-HDL cholesterol ratio with heart rate recovery
Mehdi H Shishehbor
Department of Internal Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Diabetes Care 27:936-41. 2004
..49, 95% CI 1.08-2.04; P = 0.015). CONCLUSIONS: HRR is associated with triglyceride-to-HDL cholesterol ratio and identifies patients with insulin resistance who are at increased risk of death...
- Association of educational status with heart rate recovery: a population-based propensity analysis
Mehdi H Shishehbor
Department of Internal Medicine (MHS, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Am J Med 113:643-9. 2002
..However, after accounting for age, sex, and heart rate recovery, educational status was a weaker predictor (HR = 1.3; 95% CI: 1.0 to 1.7). CONCLUSIONS: Educational status is independently associated with an abnormal heart rate recovery...
- A review of high-dose statin therapy: targeting cholesterol and inflammation in atherosclerosis
Taral N Patel
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
Eur Heart J 28:664-72. 2007
..Further, we will discuss the evidence for effects of high-dose statin therapy on inflammation and C-reactive protein...
- Safety and efficacy of overlapping sirolimus-eluting versus paclitaxel-eluting stents
Mehdi H Shishehbor
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
Am Heart J 155:1075-80. 2008
..The short-term and long-term safety and efficacy of paclitaxel versus sirolimus-overlapping drug-eluting stents (DES) is unknown. We sought to examine the clinical consequences of overlapping sirolimus versus paclitaxel DES...
- Inflammation and atherosclerosis
Mehdi H Shishehbor
Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk F25, Cleveland, OH 44195, USA
Curr Atheroscler Rep 6:131-9. 2004
..The link between inflammation and atherosclerosis provides a new venue for future pharmacologic agents that may slow the progression of atherosclerosis by inhibiting inflammation...
- The nutcracker syndrome
Sridhar Venkatachalam
Department of Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
Ann Vasc Surg 25:1154-64. 2011
..This tabular review compiles published cases in the adult population during the period between 1980 and 2009...
- Association of nitrotyrosine levels with cardiovascular disease and modulation by statin therapy
Mehdi H Shishehbor
Department of Cell Biology, and the Center for Cardiovascular Diagnostics and Prevention, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
JAMA 289:1675-80. 2003
..These results suggest a potential role for nitric oxide-derived oxidants as inflammatory mediators in CAD and may have implications for atherosclerosis risk assessment and monitoring of anti-inflammatory actions of statins...
- Jupiter to earth: a statin helps people with normal LDL-C and high hs-CRP, but what does it mean?
Mehdi H Shishehbor
National Institutes of Health CTSA KL2 Scholar, Department of Interventional Cardiology, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Cleve Clin J Med 76:37-44. 2009
..In absolute terms, 95 people had to be treated over 2 years to prevent one event. There was, however, a higher incidence of diabetes in the rosuvastatin group...
- Relation of hemoglobin A1c to left ventricular relaxation in patients with type 1 diabetes mellitus and without overt heart disease
Mehdi H Shishehbor
Department of Internal Medicine, Cardiovascular Imaging Center, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Am J Cardiol 91:1514-7, A9. 2003
- Outcomes of Culprit Versus Multivessel PCI in Patients With Multivessel Coronary Artery Disease Presenting With ST-Elevation Myocardial Infarction Complicated by Shock
Matthew A Cavender
Department of Cardiovascular Medicine, Cleveland Clinic, 9500 Euclid Avenue, J3 5, Cleveland, OH 44195 USA
J Invasive Cardiol 25:218-24. 2013
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- Renal denervation to treat resistant hypertension: Guarded optimism
George Thomas
Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic
Cleve Clin J Med 79:501-10. 2012
..But although there is reason for cautious optimism, we should keep in mind that the mechanisms of hypertension are complex and multifactorial, and further study of this novel therapy and its long-term effects is needed...
- Prognosis on chronic dobutamine or milrinone infusions for stage D heart failure
Eiran Z Gorodeski
Section of Heart Failure and Cardiac Transplant Medicine, Kaufman Center for Heart Failure, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Circ Heart Fail 2:320-4. 2009
..There are no published clinical trials comparing dobutamine with milrinone in outpatients with stage D heart failure on continuous inotropes...
- Serum myeloperoxidase levels independently predict endothelial dysfunction in humans
Joseph A Vita
Evans Department of Medicine and Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Mass, USA
Circulation 110:1134-9. 2004
..Myeloperoxidase-mediated endothelial dysfunction may be an important mechanistic link between oxidation, inflammation, and cardiovascular disease...
- Antioxidant studies need a change of direction
Mehdi H Shishehbor
Cleve Clin J Med 71:285-8. 2004
- Prevalence, awareness, treatment, and risk factors associated with hypertension in the Iranian population: the national survey of risk factors for noncommunicable diseases of Iran
Alireza Esteghamati
Endocrine Research Center, Valiasr Hospital, Tehran University of Medical Sciences, Tehran, Iran
Am J Hypertens 21:620-6. 2008
..The prevalence of hypertension in the Middle East is not well defined. We examined the prevalence, awareness, treatment, and control of hypertension in Iran...
- Xuezhikang, an extract of cholestin, protects endothelial function through antiinflammatory and lipid-lowering mechanisms in patients with coronary heart disease
Shui Ping Zhao
Department of Cardiology, Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, PR China
Circulation 110:915-20. 2004
..05). CONCLUSIONS: Xuezhikang effectively improved preprandial and postprandial endothelial function through its potent antiinflammatory and lipid-lowering effects...
