David Pierce

Summary

Affiliation: Shire BioChem Inc

Publications

  1. doi request reprint Pharmacokinetics of methylphenidate transdermal system (MTS): results from a laboratory classroom study
    David Pierce
    Shire Pharmaceutical Development Ltd, Basingstoke, United Kingdom
    J Child Adolesc Psychopharmacol 18:355-64. 2008
  2. doi request reprint Assessment of pharmacodynamic equivalence and tolerability of lanthanum carbonate oral powder and tablet formulations: a single-center, randomized, open-label, 2-period crossover study in healthy subjects
    David Pierce
    Shire Pharmaceutical Development Ltd, Basingstoke, United Kingdom
    Clin Ther 34:1290-1300.e2. 2012
  3. doi request reprint Single- and multiple-dose pharmacokinetics of methylphenidate administered as methylphenidate transdermal system or osmotic-release oral system methylphenidate to children and adolescents with attention deficit hyperactivity disorder
    David Pierce
    Shire Pharmaceutical Development Ltd, Hampshire International Business Park, Chineham, Basingstoke, Hampshire, UK
    J Clin Psychopharmacol 30:554-64. 2010
  4. pmc The effect of sevelamer carbonate and lanthanum carbonate on the pharmacokinetics of oral calcitriol
    David Pierce
    Shire Pharmaceutical Development Ltd, Chineham, Hampshire, UK
    Nephrol Dial Transplant 26:1615-21. 2011

Detail Information

Publications4

  1. doi request reprint Pharmacokinetics of methylphenidate transdermal system (MTS): results from a laboratory classroom study
    David Pierce
    Shire Pharmaceutical Development Ltd, Basingstoke, United Kingdom
    J Child Adolesc Psychopharmacol 18:355-64. 2008
    ..To evaluate the pharmacokinetic properties of the methylphenidate transdermal system (MTS) in pediatric patients diagnosed with ADHD (attention-deficit/hyperactivity disorder) in a laboratory school setting...
  2. doi request reprint Assessment of pharmacodynamic equivalence and tolerability of lanthanum carbonate oral powder and tablet formulations: a single-center, randomized, open-label, 2-period crossover study in healthy subjects
    David Pierce
    Shire Pharmaceutical Development Ltd, Basingstoke, United Kingdom
    Clin Ther 34:1290-1300.e2. 2012
    ..Lanthanum carbonate (LC) is a phosphate binder currently available as a chewable tablet. This study was conducted to support an application for marketing authorization for the oral powder formulation within the European Union...
  3. doi request reprint Single- and multiple-dose pharmacokinetics of methylphenidate administered as methylphenidate transdermal system or osmotic-release oral system methylphenidate to children and adolescents with attention deficit hyperactivity disorder
    David Pierce
    Shire Pharmaceutical Development Ltd, Hampshire International Business Park, Chineham, Basingstoke, Hampshire, UK
    J Clin Psychopharmacol 30:554-64. 2010
    ..After all dosing, systemic exposure was greater in children compared with adolescents, consistent with lower body weight in children. Adverse events were mild to moderate for both formulations, and MTS dermal responses were mild...
  4. pmc The effect of sevelamer carbonate and lanthanum carbonate on the pharmacokinetics of oral calcitriol
    David Pierce
    Shire Pharmaceutical Development Ltd, Chineham, Hampshire, UK
    Nephrol Dial Transplant 26:1615-21. 2011
    ..Patients with CKD may require intravenous or oral active vitamin D. We investigated the effects of lanthanum carbonate and sevelamer carbonate on the bioavailability of oral calcitriol...