Taekyun Shin

Summary

Publications

  1. doi request reprint The pleiotropic effects of galectin-3 in neuroinflammation: a review
    Taekyun Shin
    Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 690 756, Republic of Korea
    Acta Histochem 115:407-11. 2013
  2. ncbi request reprint Mechanism of experimental autoimmune neuritis in Lewis rats: the dual role of macrophages
    Taekyun Shin
    Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju, Republic of Korea
    Histol Histopathol 28:679-84. 2013
  3. doi request reprint Alternatively activated macrophages in spinal cord injury and remission: another mechanism for repair?
    Taekyun Shin
    Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 690 756, Republic of Korea
    Mol Neurobiol 47:1011-9. 2013
  4. doi request reprint Osteopontin as a two-sided mediator in acute neuroinflammation in rat models
    Taekyun Shin
    Department of Veterinary Anatomy, College of Veterinary Medicine, Jeju National University, Republic of Korea
    Acta Histochem 114:749-54. 2012
  5. doi request reprint Radioprotective effects of fucoidan in mice treated with total body irradiation
    Jeeyoung Lee
    Department of Veterinary Medicine, College of Veterinary Medicine, Cheju National University, Jeju 690 756, South Korea
    Phytother Res 22:1677-81. 2008
  6. doi request reprint Galectin-3 immunohistochemistry in the vomeronasal organ of the domestic pig, Sus scrofa
    Changnam Park
    Laboratory of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 690 756, South Korea
    Acta Histochem 114:713-8. 2012
  7. doi request reprint Immunohistochemical study of arginase-1 in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis
    Meejung Ahn
    Department of Anatomy, School of Medicine, Jeju National University, Jeju 690 756, South Korea
    Brain Res 1453:77-86. 2012
  8. doi request reprint Potential role of fibronectin in microglia/macrophage activation following cryoinjury in the rat brain: an immunohistochemical study
    Heechul Kim
    Laboratory of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 690 756, Republic of Korea
    Brain Res 1502:11-9. 2013
  9. pmc Differential patterns of nestin and glial fibrillary acidic protein expression in mouse hippocampus during postnatal development
    Joong Sun Kim
    Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National University, Gwangju 500 757, Korea
    J Vet Sci 12:1-6. 2011
  10. doi request reprint Immunohistochemical localization of galectin-3 in the reproductive organs of the cow
    Mia Kim
    Department of Veterinary Medicine, College of Veterinary Medicine, Cheju National University, Jeju 690 756, South Korea
    Acta Histochem 110:473-80. 2008

Collaborators

  • Changjong Moon
  • Hong Gu Joo
  • Sung Ho Kim
  • Yoh Matsumoto
  • Seung Sook Lee
  • Kazumi Taniguchi
  • Hyung Min Kim
  • Meejung Ahn
  • Miyoung Yang
  • Joong Sun Kim
  • Youngheun Jee
  • Chanwoo Jeong
  • Jin Won Hyun
  • Jong Choon Kim
  • Jae Kwang Jin
  • Jae Woo Park
  • Mia Kim
  • Jihoon Kim
  • Sungyoung Choi
  • Changnam Park
  • Eun Ju Ko
  • Ginnae Ahn
  • Nam Ho Lee
  • Yun Young Byon
  • Juyeon Lee
  • Jeongtae Kim
  • Mei Jing Piao
  • Junwoo Park
  • Gi Ok Kim
  • Juhwan Kim
  • Wonjun Yang
  • Hanseul Oh
  • Eunjin Park
  • Hyosun Jang
  • Ryeo Kyeong Ko
  • Myoung Sub Song
  • Chang Sung Koh
  • So Jin Bing
  • Jinwoo Jeong
  • Chanwoo Jung
  • Jeeyoung Lee
  • Do Sik Min
  • JongChul Kang
  • Ki Cheon Kim
  • Kyoung Ah Kang
  • Sungwook Chae
  • Wonho Lee
  • Ki Bum Sim
  • Kyungsook Jung
  • Hongbing Wang
  • Jun Hwa Lee
  • Cheolho Lee
  • Sungwoong Jang
  • Yujin Kim
  • You Jin Jeon
  • Won Woo Lee
  • Sungwoon Kang
  • Ki Wan Lee
  • Tae Wook Hahn
  • Seung Chun Park
  • Min Ju Kim
  • Won Suk Jang
  • Min Kyoung Shin
  • Heejin Oui
  • Dae Seung Kim
  • Keun Hwa Lee
  • Mi Yeon Moon
  • Mi Hyoung Kim
  • Kyu Kye Hwang
  • Eun Sook Yoo

Detail Information

Publications43

  1. doi request reprint The pleiotropic effects of galectin-3 in neuroinflammation: a review
    Taekyun Shin
    Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 690 756, Republic of Korea
    Acta Histochem 115:407-11. 2013
    ..The available information indicates that galectin-3 is essential for normal brain development and plays diverse roles in CNS inflammation, combining pro-inflammatory roles with re-modeling capacity in damaged CNS tissues...
  2. ncbi request reprint Mechanism of experimental autoimmune neuritis in Lewis rats: the dual role of macrophages
    Taekyun Shin
    Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju, Republic of Korea
    Histol Histopathol 28:679-84. 2013
    ..A better understanding of macrophages may help to design alternative therapeutic strategies for organ-specific autoimmune diseases, including GBS...
  3. doi request reprint Alternatively activated macrophages in spinal cord injury and remission: another mechanism for repair?
    Taekyun Shin
    Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 690 756, Republic of Korea
    Mol Neurobiol 47:1011-9. 2013
    ..This review summarizes the potential roles of alternatively activated macrophages in the course of CNS inflammation in rodent SCI models...
  4. doi request reprint Osteopontin as a two-sided mediator in acute neuroinflammation in rat models
    Taekyun Shin
    Department of Veterinary Anatomy, College of Veterinary Medicine, Jeju National University, Republic of Korea
    Acta Histochem 114:749-54. 2012
    ..All of these models are characterized by acute neuroinflammation, followed by remodeling of neural tissues...
  5. doi request reprint Radioprotective effects of fucoidan in mice treated with total body irradiation
    Jeeyoung Lee
    Department of Veterinary Medicine, College of Veterinary Medicine, Cheju National University, Jeju 690 756, South Korea
    Phytother Res 22:1677-81. 2008
    ....
  6. doi request reprint Galectin-3 immunohistochemistry in the vomeronasal organ of the domestic pig, Sus scrofa
    Changnam Park
    Laboratory of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 690 756, South Korea
    Acta Histochem 114:713-8. 2012
    ..In view of these observations, we postulate that galectin-3 plays a role in cell survival and cell adhesion in both the VSE and VRE of porcine VNO in all age groups...
  7. doi request reprint Immunohistochemical study of arginase-1 in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis
    Meejung Ahn
    Department of Anatomy, School of Medicine, Jeju National University, Jeju 690 756, South Korea
    Brain Res 1453:77-86. 2012
    ....
  8. doi request reprint Potential role of fibronectin in microglia/macrophage activation following cryoinjury in the rat brain: an immunohistochemical study
    Heechul Kim
    Laboratory of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 690 756, Republic of Korea
    Brain Res 1502:11-9. 2013
    ....
  9. pmc Differential patterns of nestin and glial fibrillary acidic protein expression in mouse hippocampus during postnatal development
    Joong Sun Kim
    Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National University, Gwangju 500 757, Korea
    J Vet Sci 12:1-6. 2011
    ....
  10. doi request reprint Immunohistochemical localization of galectin-3 in the reproductive organs of the cow
    Mia Kim
    Department of Veterinary Medicine, College of Veterinary Medicine, Cheju National University, Jeju 690 756, South Korea
    Acta Histochem 110:473-80. 2008
    ..In addition, galectin-3 plays an important role in the regression of follicles and the corpus luteum...
  11. doi request reprint Immunohistochemical study of arginase-1 in the spinal cords of rats with clip compression injury
    Meejung Ahn
    Department of Anatomy, School of Medicine, Jeju National University, Jeju 690 756, Republic of Korea
    Brain Res 1445:11-9. 2012
    ..These findings suggest that the increased level of arginase-1 in SCI is associated with an increase in macrophages and reactive astrocytes, possibly contributing to the modulation of inflammation during the course of SCI...
  12. pmc Cytotoxicity of gamma-ray in rat immature hippocampal neurons
    Miyoung Yang
    Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National, University, Gwangju 500 757, Korea
    J Vet Sci 12:203-7. 2011
    ..The results suggest that the caspase-dependent cytotoxicity of γ-rays in immature hippocampal cultured neurons may be caused by oxidative stress...
  13. doi request reprint Heat shock protein 27 upregulation and phosphorylation in rat experimental autoimmune encephalomyelitis
    Heechul Kim
    Department of Veterinary Anatomy, College of Veterinary Medicine, Veterinary Medical Research Institute, Jeju National University, 1 Ara 1 Dong, Jeju, Jeju 690 756, South Korea
    Brain Res 1304:155-63. 2009
    ..Our results also suggest that HSP27 plays a role in spontaneous recovery from EAE-induced paralysis...
  14. doi request reprint Immunohistochemical study of netrin-1 in the spinal cord with rat experimental autoimmune encephalomyelitis
    Changjong Moon
    Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National University, Gwangju 500 757, South Korea
    Immunol Invest 40:160-71. 2011
    ..These results suggest that netrin-1 is transiently increased in rat EAE lesions, where it contributes to the modulation of rat acute EAE...
  15. doi request reprint Glial cell line-derived neurotrophic factor is expressed by inflammatory cells in the sciatic nerves of Lewis rats with experimental autoimmune neuritis
    Meejung Ahn
    Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju, South Korea
    J Peripher Nerv Syst 15:104-12. 2010
    ..Collectively, we postulate that GDNF plays a regulatory role in EAN paralysis. A paradoxical role of inflammatory cells to ameliorate PNS inflammation remains to be further studied in EAN, an animal model of human demyelinating disease...
  16. pmc Immunohistochemical localization of galectin-3 in the granulomatous lesions of paratuberculosis-infected bovine intestine
    Juyeon Lee
    Department of Veterinary Anatomy, College of Veterinary Medicine and Applied Radiological Science Research Institute, Jeju National University, Jeju 690 756, Korea
    J Vet Sci 10:177-80. 2009
    ..These findings suggest that galectin-3 is associated with the formation of chronic granulation tissues in bovine paratuberculosis, probably through cell adhesion and anti-apoptosis mechanisms...
  17. doi request reprint Diphlorethohydroxycarmalol, isolated from the brown algae Ishige okamurae, protects against radiation-induced cell damage in mice
    Meejung Ahn
    Department of Anatomy, College of Medicine, Jeju National University, Jeju 690 756, South Korea
    Food Chem Toxicol 49:864-70. 2011
    ....
  18. pmc Immunohistochemical localization of galectin-3 in the pig retina during postnatal development
    Jihoon Kim
    Department of Veterinary Anatomy, College of Veterinary Medicine, Jeju National University, Jeju, South Korea
    Mol Vis 15:1971-6. 2009
    ..The differential level and localization of galectin-3 protein were examined in the retinas of two-day-old pigs and six-month-old pigs...
  19. doi request reprint Granulocyte-colony stimulating factor ameliorates irradiation-induced suppression of hippocampal neurogenesis in adult mice
    Joong Sun Kim
    Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National University, Gwangju 500 757, South Korea
    Neurosci Lett 486:43-6. 2010
    ..Therefore, G-csf inhibited the detrimental effects of irradiation on hippocampal neurogenesis, suggesting that G-csf administration has potential therapeutic utility in brain irradiation...
  20. doi request reprint Developmental levels of phospholipase D isozymes in the brain of developing rats
    Mia Kim
    Department of Veterinary Anatomy, Applied Radiological Science Research Institute, Cheju National University, Jeju, South Korea
    Acta Histochem 112:81-91. 2010
    ..These findings suggest that PLD may differentially play a role in the course of early development of the brain, with special reference to the cerebrum and hindbrain, in rats...
  21. pmc Radioprotective effects of fucoidan on bone marrow cells: improvement of the cell survival and immunoreactivity
    Yun Young Byon
    College of Veterinary Medicine, Cheju National University, Jeju 690 756, Korea
    J Vet Sci 9:359-65. 2008
    ..Taken together, our study demonstrated that fucoidan has radioprotective effects on BMCs with respect to cell viability and immunoreactivity. These results may provide valuable information, useful in the field of radiotherapy...
  22. doi request reprint Enzymatic extract from Ecklonia cava induces the activation of lymphocytes by IL-2 production through the classical NF-κB pathway
    Ginnae Ahn
    Department of Marine Life Science, Jeju National University, Jeju, 690 756, Republic of Korea
    Mar Biotechnol (NY) 13:66-73. 2011
    ..Accordingly, our results suggest that ECK increases the production of IL-2 through the activation of NF-κB then induces the proliferation of lymphocytes with the coordinated stimulation of IL-2...
  23. doi request reprint Acute treatment with methotrexate induces hippocampal dysfunction in a mouse model of breast cancer
    Miyoung Yang
    Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National University, Gwangju, South Korea
    Brain Res Bull 89:50-6. 2012
    ....
  24. ncbi request reprint Transient expression of phospholipase D1 during heart development in rats
    Changjong Moon
    Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National University, Gwangju, Republic of Korea
    J Vet Med Sci 70:411-3. 2008
    ..This suggests that the PLD1 protein in the heart is strongly associated with the early postnatal development of the heart in rats...
  25. doi request reprint Immunohistochemical study of arginase 1 and 2 in various tissues of rats
    Sungyoung Choi
    Laboratory of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Republic of Korea
    Acta Histochem 114:487-94. 2012
    ..These findings indicate that the levels of arginase 1 and 2 varied among organs, suggesting that the arginase isoforms may play organ-specific roles in the urea cycle...
  26. pmc Maturation of bone marrow-derived dendritic cells by a novel β-glucan purified from Paenibacillus polymyxa JB115
    Eun Ju Ko
    College of Veterinary Medicine, Jeju National University, Jeju 690 756, Korea
    J Vet Sci 12:187-9. 2011
    ..These results demonstrate the effect of β-glucan on DC maturation and may increase the use of β-glucan...
  27. pmc Immunohistochemical study of galectin-3 in mature and immature bull testis and epididymis
    Hwanglyong Kim
    College of Veterinary Medicine, Cheju National University, Jeju 690 756, Korea
    J Vet Sci 9:339-44. 2008
    ..These findings suggest that galectin-3 expression plays a role in the maturation and activation of sperm in bulls...
  28. ncbi request reprint 1,2,3,4,6-penta-O-galloyl-beta-D-glucose protects splenocytes against radiation-induced apoptosis in murine splenocytes
    So Jin Bing
    Department of Veterinary Medicine and Applied Radiological Science Research Institute, Jeju National University, Jeju 690 756, South Korea
    Biol Pharm Bull 33:1122-7. 2010
    ..The results presented in this study suggest that PGG has a cytoprotective effect on immune cells exposed to normally damaging amount of radiation. Thus, PGG could be an effective, non-toxic radioprotective agent...
  29. doi request reprint Dose-response and relative biological effectiveness of fast neutrons: induction of apoptosis and inhibition of neurogenesis in the hippocampus of adult mice
    Miyoung Yang
    Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National University, Buk Gu, Gwangju, South Korea
    Int J Radiat Biol 86:476-85. 2010
    ....
  30. doi request reprint Amelioration of experimental autoimmune encephalomyelitis in Lewis rats treated with fucoidan
    Heechul Kim
    Department of Veterinary Anatomy, College of Veterinary Medicine and Applied Radiological Science Research Institute, Jeju National University, Jeju 690 756, South Korea
    Phytother Res 24:399-403. 2010
    ..The ameliorative effect of fucoidan on clinical paralysis in EAE-affected rats may be mediated, in part, by the suppression of the autoreactive T cell response and inflammatory cytokine production...
  31. doi request reprint Upregulation of erythropoietin in rat peripheral nervous system with experimental autoimmune neuritis
    Meejung Ahn
    Department of Veterinary Anatomy, College of Veterinary Medicine, Veterinary Medical Research Institute, Jeju National University, Jeju 690 756, South Korea
    Brain Res 1333:82-90. 2010
    ..These findings suggest that EPO is transiently upregulated in EAN lesions and that the EPO/EPO-receptor binding pathway is associated with neuroprotection in EAN-affected PNS tissues...
  32. doi request reprint Immunohistochemical localization of protein kinase C-alpha in the retina of pigs during postnatal development
    Meejung Ahn
    Department of Veterinary Anatomy, College of Veterinary Medicine, Jeju National University, Jeju 690 756, South Korea
    Neurosci Lett 455:93-6. 2009
    ..This study demonstrates that the protein level of retinal PKC-alpha is increased with maturation and suggests that PKC-alpha plays a role in signal transduction pathways for postnatal development in porcine retina...
  33. pmc Immunohistochemical localization of cyclic AMP-responsive element binding protein (CREB)-binding protein in the pig retina during postnatal development
    Hanseul Oh
    Department of Veterinary Anatomy, Veterinary Medical Research Institute, College of Veterinary Medicine, Jeju National University, Jeju, Korea
    Anat Cell Biol 44:143-50. 2011
    ....
  34. ncbi request reprint Expression of CD44 adhesion molecule in rat testis with ischemia/reperfusion injury
    Changjong Moon
    Department of Veterinary Medicine, College of Applied Life Science and Applied Radiological Science Research Institute, Cheju National University, Jeju, Republic of Korea
    J Vet Med Sci 68:761-4. 2006
    ....
  35. doi request reprint Immunohistochemical localization of protein kinase C (PKC) beta I in the pig retina during postnatal development
    Chanwoo Jeong
    Laboratory of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, South Korea
    Acta Histochem 114:18-23. 2012
    ....
  36. pmc Erythropoietin and autoimmune neuroinflammation: lessons from experimental autoimmune encephalomyelitis and experimental autoimmune neuritis
    Taekyun Shin
    Department of Veterinary Anatomy, Veterinary Medical Research Institute, College of Veterinary Medicine, Jeju National University, Jeju, Korea
    Anat Cell Biol 45:215-20. 2012
    ..In addition, the immunomodulatory role of EPO in the pathogenesis of EAE and EAN animal models of human multiple sclerosis and Guillain-Barré syndrome, respectively, will be discussed...
  37. ncbi request reprint Increased expression of osteopontin in the heart tissue of Lewis rats with experimental autoimmune myocarditis
    Taekyun Shin
    Department of Veterinary Medicine, Cheju National University, Jeju, Republic of Korea
    J Vet Med Sci 68:379-82. 2006
    ..These findings suggest that OPN is significantly increased in EAM lesions and that OPN mediates the inflammatory process in the course of rat EAM model...
  38. ncbi request reprint Activation of Akt/protein kinase B and extracellular signal-regulated kinase in rats with acute experimental testicular torsion
    Changjong Moon
    Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National University, Gwangju, South Korea
    J Vet Med Sci 70:337-41. 2008
    ..These pathways may represent important targets for increasing cell survival in testicular injury, including testicular torsion...
  39. pmc Mechanism of experimental autoimmune encephalomyelitis in Lewis rats: recent insights from macrophages
    Taekyun Shin
    Department of Veterinary Anatomy, Veterinary Medical Research Institute, College of Veterinary Medicine, Jeju National University, Jeju, Korea Functional and Systems Neurobiology, Cajal Institute, Madrid, Spain
    Anat Cell Biol 45:141-8. 2012
    ....
  40. ncbi request reprint Phospholipase D1 is up-regulated in the retina of Lewis rats with experimental autoimmune uveoretinitis
    JongChul Kang
    Department of Veterinary Medicine, College of Agriculture and Life Science, Cheju National University, Jeju, Republic of Korea
    Immunol Invest 34:27-36. 2005
    ....
  41. doi request reprint Developmental changes affecting lectin binding in the vomeronasal organ of domestic pigs, Sus scrofa
    Junwoo Park
    Laboratory of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, South Korea
    Acta Histochem 114:24-30. 2012
    ..These findings suggest that binding sites of lectins, including those of WGA, UEA-I, DBA, and SBA, increase during development from fetal to postnatal growth, possibly contributing to the increased ability of chemoreception in the pig...
  42. doi request reprint Diphlorethohydroxycarmalol attenuated cell damage against UVB radiation via enhancing antioxidant effects and absorbing UVB ray in human HaCaT keratinocytes
    Mei Jing Piao
    School of Medicine, Jeju National University, Jeju 690 756, Republic of Korea
    Environ Toxicol Pharmacol 36:680-8. 2013
    ..These results suggest that DPHC safeguards human keratinocytes against UVB-induced cell damage by absorbing UVB ray, scavenging ROS and enhancing antioxidant system. ..
  43. pmc The radioprotective effects of the hexane and ethyl acetate extracts of Callophyllis japonica in mice that undergo whole body irradiation
    Jeongtae Kim
    College of Veterinary Medicine, and the Research Institute for Subtropical Agriculture and Biotechnology, Cheju National University, Jeju 690 756, Korea
    J Vet Sci 9:281-4. 2008
    ....