Taekyun Shin

Summary

Publications

  1. pmc Immunohistochemical localization of cyclic AMP-responsive element binding protein (CREB)-binding protein in the pig retina during postnatal development
    Hanseul Oh
    Department of Veterinary Anatomy, Veterinary Medical Research Institute, College of Veterinary Medicine, Jeju National University, Jeju, Korea
    Anat Cell Biol 44:143-50. 2011
  2. pmc Mechanism of experimental autoimmune encephalomyelitis in Lewis rats: recent insights from macrophages
    Taekyun Shin
    Department of Veterinary Anatomy, Veterinary Medical Research Institute, College of Veterinary Medicine, Jeju National University, Jeju, Korea Functional and Systems Neurobiology, Cajal Institute, Madrid, Spain
    Anat Cell Biol 45:141-8. 2012
  3. pmc Differential patterns of nestin and glial fibrillary acidic protein expression in mouse hippocampus during postnatal development
    Joong Sun Kim
    Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National University, Gwangju 500 757, Korea
    J Vet Sci 12:1-6. 2011
  4. pmc Erythropoietin and autoimmune neuroinflammation: lessons from experimental autoimmune encephalomyelitis and experimental autoimmune neuritis
    Taekyun Shin
    Department of Veterinary Anatomy, Veterinary Medical Research Institute, College of Veterinary Medicine, Jeju National University, Jeju, Korea
    Anat Cell Biol 45:215-20. 2012
  5. pmc Possible role of the glycogen synthase kinase-3 signaling pathway in trimethyltin-induced hippocampal neurodegeneration in mice
    Juhwan Kim
    Departments of Veterinary Anatomy and Veterinary Toxicology, College of Veterinary Medicine and Animal Medical Institute, Chonnam National University, Gwangju, Republic of Korea
    PLoS ONE 8:e70356. 2013
  6. doi request reprint The pleiotropic effects of galectin-3 in neuroinflammation: a review
    Taekyun Shin
    Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 690 756, Republic of Korea
    Acta Histochem 115:407-11. 2013
  7. doi request reprint Alternatively activated macrophages in spinal cord injury and remission: another mechanism for repair?
    Taekyun Shin
    Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 690 756, Republic of Korea
    Mol Neurobiol 47:1011-9. 2013
  8. ncbi request reprint Mechanism of experimental autoimmune neuritis in Lewis rats: the dual role of macrophages
    Taekyun Shin
    Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju, Republic of Korea
    Histol Histopathol 28:679-84. 2013
  9. ncbi request reprint Osteopontin as a two-sided mediator in acute neuroinflammation in rat models
    Taekyun Shin
    Department of Veterinary Anatomy, College of Veterinary Medicine, Jeju National University, Republic of Korea
    Acta Histochem 114:749-54. 2012
  10. doi request reprint Cyclophosphamide impairs hippocampus-dependent learning and memory in adult mice: Possible involvement of hippocampal neurogenesis in chemotherapy-induced memory deficits
    Miyoung Yang
    College of Veterinary Medicine, Chonnam National University and Animal Medical Institute, Gwangju 500 757, South Korea
    Neurobiol Learn Mem 93:487-94. 2010

Collaborators

  • Changjong Moon
  • Sung Ho Kim
  • Hong Gu Joo
  • Yoh Matsumoto
  • Kazumi Taniguchi
  • Seung Sook Lee
  • Young Ho Lee
  • Uhee Jung
  • Chitoshi Takayama
  • Jie Young Song
  • Minsoo Kim
  • Hyung Min Kim
  • Jeong Tae Kim
  • Meejung Ahn
  • Miyoung Yang
  • Myoung Sub Song
  • Hongbing Wang
  • Chanwoo Jeong
  • Youngheun Jee
  • Jin Won Hyun
  • Heung Sik Seo
  • Jae Woo Park
  • Sungyoung Choi
  • Changnam Park
  • Eun Ju Ko
  • Ginnae Ahn
  • Jae Kwang Jin
  • Chun Sik Bae
  • Yun Young Byon
  • Jeeyoung Lee
  • Yeonghoon Son
  • Mei Jing Piao
  • Gi Ok Kim
  • Junwoo Park
  • Wonjun Yang
  • Hanseul Oh
  • Ki Bum Sim
  • Eunjin Park
  • Ryeo Kyeong Ko
  • Nam Ho Lee
  • Chang Sung Koh
  • So Jin Bing
  • Juyeon Lee
  • Chanwoo Jung
  • Yujin Kim
  • JongChul Kang
  • Sung Kee Jo
  • Kyoung Ah Kang
  • Ki Cheon Kim
  • Sungwook Chae
  • Cheolho Lee
  • Sungwoong Jang
  • Taehyub Kim
  • Akinobu Hayashi
  • Kyungsook Jung
  • Wonho Lee
  • Jun Hwa Lee
  • You Jin Jeon
  • Won Woo Lee
  • Ki Wan Lee
  • Seung Chun Park
  • Tae Wook Hahn
  • Jinwoo Jeong
  • Seong Soo Kang
  • Soo Hyun Park
  • Dae Seung Kim
  • Keun Hwa Lee
  • Eun Sook Yoo
  • Kyu Kye Hwang
  • Do Sik Min

Detail Information

Publications67

  1. pmc Immunohistochemical localization of cyclic AMP-responsive element binding protein (CREB)-binding protein in the pig retina during postnatal development
    Hanseul Oh
    Department of Veterinary Anatomy, Veterinary Medical Research Institute, College of Veterinary Medicine, Jeju National University, Jeju, Korea
    Anat Cell Biol 44:143-50. 2011
    ....
  2. pmc Mechanism of experimental autoimmune encephalomyelitis in Lewis rats: recent insights from macrophages
    Taekyun Shin
    Department of Veterinary Anatomy, Veterinary Medical Research Institute, College of Veterinary Medicine, Jeju National University, Jeju, Korea Functional and Systems Neurobiology, Cajal Institute, Madrid, Spain
    Anat Cell Biol 45:141-8. 2012
    ....
  3. pmc Differential patterns of nestin and glial fibrillary acidic protein expression in mouse hippocampus during postnatal development
    Joong Sun Kim
    Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National University, Gwangju 500 757, Korea
    J Vet Sci 12:1-6. 2011
    ....
  4. pmc Erythropoietin and autoimmune neuroinflammation: lessons from experimental autoimmune encephalomyelitis and experimental autoimmune neuritis
    Taekyun Shin
    Department of Veterinary Anatomy, Veterinary Medical Research Institute, College of Veterinary Medicine, Jeju National University, Jeju, Korea
    Anat Cell Biol 45:215-20. 2012
    ..In addition, the immunomodulatory role of EPO in the pathogenesis of EAE and EAN animal models of human multiple sclerosis and Guillain-Barré syndrome, respectively, will be discussed...
  5. pmc Possible role of the glycogen synthase kinase-3 signaling pathway in trimethyltin-induced hippocampal neurodegeneration in mice
    Juhwan Kim
    Departments of Veterinary Anatomy and Veterinary Toxicology, College of Veterinary Medicine and Animal Medical Institute, Chonnam National University, Gwangju, Republic of Korea
    PLoS ONE 8:e70356. 2013
    ..Therefore, lithium inhibited the detrimental effects of TMT on the hippocampal neurons in vivo and in vitro, suggesting involvement of the GSK-3/β-catenin signaling pathway in TMT-induced hippocampal cell degeneration and dysfunction. ..
  6. doi request reprint The pleiotropic effects of galectin-3 in neuroinflammation: a review
    Taekyun Shin
    Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 690 756, Republic of Korea
    Acta Histochem 115:407-11. 2013
    ..The available information indicates that galectin-3 is essential for normal brain development and plays diverse roles in CNS inflammation, combining pro-inflammatory roles with re-modeling capacity in damaged CNS tissues...
  7. doi request reprint Alternatively activated macrophages in spinal cord injury and remission: another mechanism for repair?
    Taekyun Shin
    Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 690 756, Republic of Korea
    Mol Neurobiol 47:1011-9. 2013
    ..This review summarizes the potential roles of alternatively activated macrophages in the course of CNS inflammation in rodent SCI models...
  8. ncbi request reprint Mechanism of experimental autoimmune neuritis in Lewis rats: the dual role of macrophages
    Taekyun Shin
    Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju, Republic of Korea
    Histol Histopathol 28:679-84. 2013
    ..A better understanding of macrophages may help to design alternative therapeutic strategies for organ-specific autoimmune diseases, including GBS...
  9. ncbi request reprint Osteopontin as a two-sided mediator in acute neuroinflammation in rat models
    Taekyun Shin
    Department of Veterinary Anatomy, College of Veterinary Medicine, Jeju National University, Republic of Korea
    Acta Histochem 114:749-54. 2012
    ..All of these models are characterized by acute neuroinflammation, followed by remodeling of neural tissues...
  10. doi request reprint Cyclophosphamide impairs hippocampus-dependent learning and memory in adult mice: Possible involvement of hippocampal neurogenesis in chemotherapy-induced memory deficits
    Miyoung Yang
    College of Veterinary Medicine, Chonnam National University and Animal Medical Institute, Gwangju 500 757, South Korea
    Neurobiol Learn Mem 93:487-94. 2010
    ..We suggest that the administration of a chemotherapeutic agent in adult mice interrupts hippocampal functions, including learning and memory, possibly through the suppression of hippocampal neurogenesis...
  11. doi request reprint Dose-response and relative biological effectiveness of fast neutrons: induction of apoptosis and inhibition of neurogenesis in the hippocampus of adult mice
    Miyoung Yang
    Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National University, Buk Gu, Gwangju, South Korea
    Int J Radiat Biol 86:476-85. 2010
    ....
  12. doi request reprint Toluene inhibits hippocampal neurogenesis in adult mice
    Heung Sik Seo
    Department of Veterinary Anatomy, College of Veterinary Medicine and Animal Medical Institute, Chonnam National University, Gwangju 500 757, South Korea
    Pharmacol Biochem Behav 94:588-94. 2010
    ..This study suggests that acute exposure to toluene reduces the rate of adult hippocampal neurogenesis and can cause hippocampal dysfunction such as depression and cognitive impairment...
  13. doi request reprint Activation of Ca2+/calmodulin-dependent protein kinase II alpha in the spinal cords of rats with clip compression injury
    Myoung Sub Song
    Department of Veterinary Anatomy, College of Veterinary Medicine and Animal Medical Institute, Chonnam National University, Gwangju 500 757, South Korea
    Brain Res 1271:114-20. 2009
    ....
  14. ncbi request reprint Eutigoside C attenuates radiation-induced crypt injury in the mouse intestine
    Changjong Moon
    Department of Veterinary Anatomy, College of Veterinary Medicine and Animal Medical Institute, Chonnam National University, Gwangju, South Korea
    Phytother Res 24:840-5. 2010
    ..05). These results suggest that eutigoside C is a useful radioprotector capable of defending intestinal progenitor cells against indirect depletion, such as oxidative stress and inflammatory response caused by gamma irradiation...
  15. ncbi request reprint Radioprotective effects of fucoidan in mice treated with total body irradiation
    Jeeyoung Lee
    Department of Veterinary Medicine, College of Veterinary Medicine, Cheju National University, Jeju 690 756, South Korea
    Phytother Res 22:1677-81. 2008
    ....
  16. pmc Increased phosphorylation of caveolin-1 in the spinal cord of irradiated rats
    Heechul Kim
    Department of Veterinary Medicine, College of Applied Life Sciences, Cheju National University, Jeju 690 756, Korea
    J Vet Sci 8:323-7. 2007
    ..These results suggest that total body irradiation induces activation of microglial cells in the spinal cord through the phosphorylation of caveolin-1...
  17. doi request reprint Immunohistochemical study of arginase-1 in the spinal cords of rats with clip compression injury
    Meejung Ahn
    Department of Anatomy, School of Medicine, Jeju National University, Jeju 690 756, Republic of Korea
    Brain Res 1445:11-9. 2012
    ..These findings suggest that the increased level of arginase-1 in SCI is associated with an increase in macrophages and reactive astrocytes, possibly contributing to the modulation of inflammation during the course of SCI...
  18. doi request reprint Potential role of fibronectin in microglia/macrophage activation following cryoinjury in the rat brain: an immunohistochemical study
    Heechul Kim
    Laboratory of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 690 756, Republic of Korea
    Brain Res 1502:11-9. 2013
    ....
  19. doi request reprint Neurotoxicity of methotrexate to hippocampal cells in vivo and in vitro
    Miyoung Yang
    Departments of Veterinary Anatomy and Veterinary Toxicology, College of Veterinary Medicine, Chonnam National University, Gwangju, South Korea
    Biochem Pharmacol 82:72-80. 2011
    ..Additionally, the significantly greater caspase-dependent MTX sensitivity of immature hippocampal cells suggests that the susceptibility of such hippocampal cells depends on their maturation...
  20. doi request reprint Heat shock protein 27 upregulation and phosphorylation in rat experimental autoimmune encephalomyelitis
    Heechul Kim
    Department of Veterinary Anatomy, College of Veterinary Medicine, Veterinary Medical Research Institute, Jeju National University, 1 Ara 1 Dong, Jeju, Jeju 690 756, South Korea
    Brain Res 1304:155-63. 2009
    ..Our results also suggest that HSP27 plays a role in spontaneous recovery from EAE-induced paralysis...
  21. doi request reprint Immunohistochemical analysis of cAMP response element-binding protein in mouse testis during postnatal development and spermatogenesis
    Joong Sun Kim
    Department of Veterinary Anatomy, College of Veterinary Medicine and Animal Medical Institute, Chonnam National University, Gwangju 500 757, South Korea
    Histochem Cell Biol 131:501-7. 2009
    ..These results suggest that CREB plays an important role in cell proliferation and differentiation in the early phase of postnatal development and spermatogenesis of mouse testis...
  22. pmc Immunohistochemical study of galectin-3 in mature and immature bull testis and epididymis
    Hwanglyong Kim
    College of Veterinary Medicine, Cheju National University, Jeju 690 756, Korea
    J Vet Sci 9:339-44. 2008
    ..These findings suggest that galectin-3 expression plays a role in the maturation and activation of sperm in bulls...
  23. ncbi request reprint Transient impairment of hippocampus-dependent learning and memory in relatively low-dose of acute radiation syndrome is associated with inhibition of hippocampal neurogenesis
    Joong Sun Kim
    Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Center, Chonnam National University, Gwangju, South Korea
    J Radiat Res 49:517-26. 2008
    ..It is suggested that a relatively low dose of ARS in adult ICR mice is sufficiently detrimental to interrupt the functioning of the hippocampus, including learning and memory, possibly through the inhibition of neurogenesis...
  24. doi request reprint Glial cell line-derived neurotrophic factor is expressed by inflammatory cells in the sciatic nerves of Lewis rats with experimental autoimmune neuritis
    Meejung Ahn
    Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju, South Korea
    J Peripher Nerv Syst 15:104-12. 2010
    ..Collectively, we postulate that GDNF plays a regulatory role in EAN paralysis. A paradoxical role of inflammatory cells to ameliorate PNS inflammation remains to be further studied in EAN, an animal model of human demyelinating disease...
  25. pmc Fast neutron irradiation deteriorates hippocampus-related memory ability in adult mice
    Miyoung Yang
    College of Veterinary Medicine and Animal Medical Institute, Chonnam National University, Gwangju 500 757, Korea
    J Vet Sci 13:1-6. 2012
    ..These results indicate that acute exposure of the adult mouse brain to a relatively low dose of fast neutrons interrupts hippocampal functions, including learning and memory, possibly by inhibiting neurogenesis...
  26. doi request reprint Upregulation of erythropoietin in rat peripheral nervous system with experimental autoimmune neuritis
    Meejung Ahn
    Department of Veterinary Anatomy, College of Veterinary Medicine, Veterinary Medical Research Institute, Jeju National University, Jeju 690 756, South Korea
    Brain Res 1333:82-90. 2010
    ..These findings suggest that EPO is transiently upregulated in EAN lesions and that the EPO/EPO-receptor binding pathway is associated with neuroprotection in EAN-affected PNS tissues...
  27. pmc The expression and localization of inhibin isotypes in mouse testis during postnatal development
    Yujin Kim
    Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Center, Chonnam National University, Gwangju 500 757, Korea
    J Vet Sci 9:345-9. 2008
    ..We conclude that the expression of inhibin isotypes increases progressively in the testis of mice with increasing postnatal age, suggesting that inhibin is associated with a negative feedback signal for FSH in testicular maturation...
  28. ncbi request reprint Differences in immunoreactivities of Ki-67 and doublecortin in the adult hippocampus in three strains of mice
    Joong Sun Kim
    Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Center, Chonnam National University, Gwangju, South Korea
    Acta Histochem 111:150-6. 2009
    ..Genetic differences with respect to certain aspects of hippocampal neurogenesis in adult mice may influence hippocampal functions, including learning and memory...
  29. pmc The radioprotective effects of the hexane and ethyl acetate extracts of Callophyllis japonica in mice that undergo whole body irradiation
    Jeongtae Kim
    College of Veterinary Medicine, and the Research Institute for Subtropical Agriculture and Biotechnology, Cheju National University, Jeju 690 756, Korea
    J Vet Sci 9:281-4. 2008
    ....
  30. doi request reprint Immunohistochemical study of arginase-1 in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis
    Meejung Ahn
    Department of Anatomy, School of Medicine, Jeju National University, Jeju 690 756, South Korea
    Brain Res 1453:77-86. 2012
    ....
  31. doi request reprint Galectin-3 immunohistochemistry in the vomeronasal organ of the domestic pig, Sus scrofa
    Changnam Park
    Laboratory of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 690 756, South Korea
    Acta Histochem 114:713-8. 2012
    ..In view of these observations, we postulate that galectin-3 plays a role in cell survival and cell adhesion in both the VSE and VRE of porcine VNO in all age groups...
  32. ncbi request reprint Gamma-ray susceptibility of immature and mature hippocampal cultured cells
    Myoung Sub Song
    College of Veterinary Medicine and Animal Medical Institute, Chonnam National University, Gwangju 500 757
    J Vet Med Sci 72:605-9. 2010
    ..In addition, gamma-irradiation may induce caspase-dependent apoptosis in immature hippocampal cells...
  33. pmc Immunohistochemical localization of galectin-3 in the pig retina during postnatal development
    Jihoon Kim
    Department of Veterinary Anatomy, College of Veterinary Medicine, Jeju National University, Jeju, South Korea
    Mol Vis 15:1971-6. 2009
    ..The differential level and localization of galectin-3 protein were examined in the retinas of two-day-old pigs and six-month-old pigs...
  34. ncbi request reprint Hippocampal dysfunction during the chronic phase following a single exposure to cranial irradiation
    Yeonghoon Son
    College of Veterinary Medicine and Animal Medical Institute, Chonnam National University, Gwangju 500 757, South Korea
    Exp Neurol 254:134-44. 2014
    ....
  35. doi request reprint Developmental levels of phospholipase D isozymes in the brain of developing rats
    Mia Kim
    Department of Veterinary Anatomy, Applied Radiological Science Research Institute, Cheju National University, Jeju, South Korea
    Acta Histochem 112:81-91. 2010
    ..These findings suggest that PLD may differentially play a role in the course of early development of the brain, with special reference to the cerebrum and hindbrain, in rats...
  36. doi request reprint Possible involvement of galectin-3 in microglial activation in the hippocampus with trimethyltin treatment
    Miyoung Yang
    College of Veterinary Medicine and Animal Medical Institute, Chonnam National University, Gwangju, South Korea
    Neurochem Int 61:955-62. 2012
    ..Therefore, we suggest that Gal-3 is involved in the inflammatory process of neurodegenerative disorder induced by organotin intoxication...
  37. doi request reprint Immunohistochemical localization of galectin-3 in the reproductive organs of the cow
    Mia Kim
    Department of Veterinary Medicine, College of Veterinary Medicine, Cheju National University, Jeju 690 756, South Korea
    Acta Histochem 110:473-80. 2008
    ..In addition, galectin-3 plays an important role in the regression of follicles and the corpus luteum...
  38. pmc Cytotoxicity of gamma-ray in rat immature hippocampal neurons
    Miyoung Yang
    Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National, University, Gwangju 500 757, Korea
    J Vet Sci 12:203-7. 2011
    ..The results suggest that the caspase-dependent cytotoxicity of γ-rays in immature hippocampal cultured neurons may be caused by oxidative stress...
  39. ncbi request reprint Transient expression of phospholipase D1 during heart development in rats
    Changjong Moon
    Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National University, Gwangju, Republic of Korea
    J Vet Med Sci 70:411-3. 2008
    ..This suggests that the PLD1 protein in the heart is strongly associated with the early postnatal development of the heart in rats...
  40. doi request reprint Acute treatment with methotrexate induces hippocampal dysfunction in a mouse model of breast cancer
    Miyoung Yang
    Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National University, Gwangju, South Korea
    Brain Res Bull 89:50-6. 2012
    ....
  41. pmc The expression and cellular localization of phospholipase D isozymes in the developing mouse testis
    Seungjoon Kim
    Department of Veterinary Medicine, College of Applied Life Sciences, Cheju National University, Jeju, Korea
    J Vet Sci 8:209-12. 2007
    ..The intense immunostaining of PLD in Leydig cells remained unchanged by postnatal week 8. These findings suggest that PLD isozymes are involved in the spermatogenesis of the mouse testis...
  42. doi request reprint Diphlorethohydroxycarmalol, isolated from the brown algae Ishige okamurae, protects against radiation-induced cell damage in mice
    Meejung Ahn
    Department of Anatomy, College of Medicine, Jeju National University, Jeju 690 756, South Korea
    Food Chem Toxicol 49:864-70. 2011
    ....
  43. doi request reprint Granulocyte-colony stimulating factor ameliorates irradiation-induced suppression of hippocampal neurogenesis in adult mice
    Joong Sun Kim
    Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National University, Gwangju 500 757, South Korea
    Neurosci Lett 486:43-6. 2010
    ..Therefore, G-csf inhibited the detrimental effects of irradiation on hippocampal neurogenesis, suggesting that G-csf administration has potential therapeutic utility in brain irradiation...
  44. doi request reprint Immunohistochemical localization of protein kinase C-alpha in the retina of pigs during postnatal development
    Meejung Ahn
    Department of Veterinary Anatomy, College of Veterinary Medicine, Jeju National University, Jeju 690 756, South Korea
    Neurosci Lett 455:93-6. 2009
    ..This study demonstrates that the protein level of retinal PKC-alpha is increased with maturation and suggests that PKC-alpha plays a role in signal transduction pathways for postnatal development in porcine retina...
  45. doi request reprint Immunohistochemical study of netrin-1 in the spinal cord with rat experimental autoimmune encephalomyelitis
    Changjong Moon
    Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National University, Gwangju 500 757, South Korea
    Immunol Invest 40:160-71. 2011
    ..These results suggest that netrin-1 is transiently increased in rat EAE lesions, where it contributes to the modulation of rat acute EAE...
  46. ncbi request reprint Activation of Akt/protein kinase B and extracellular signal-regulated kinase in rats with acute experimental testicular torsion
    Changjong Moon
    Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National University, Gwangju, South Korea
    J Vet Med Sci 70:337-41. 2008
    ..These pathways may represent important targets for increasing cell survival in testicular injury, including testicular torsion...
  47. ncbi request reprint Immunohistochemical study of cathepsin D in the spinal cords of rats with clip compression injury
    Changjong Moon
    Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Center, Chonnam National University, Gwangju, South Korea
    J Vet Med Sci 70:937-41. 2008
    ..Overall, these findings suggest that cathepsin D plays an important role in the phagocytosis and lysosomal activation of macrophages/microglia during the central nervous system inflammation caused by trauma...
  48. doi request reprint Diphlorethohydroxycarmalol attenuated cell damage against UVB radiation via enhancing antioxidant effects and absorbing UVB ray in human HaCaT keratinocytes
    Mei Jing Piao
    School of Medicine, Jeju National University, Jeju 690 756, Republic of Korea
    Environ Toxicol Pharmacol 36:680-8. 2013
    ..These results suggest that DPHC safeguards human keratinocytes against UVB-induced cell damage by absorbing UVB ray, scavenging ROS and enhancing antioxidant system. ..
  49. pmc Immunohistochemical localization of galectin-3 in the granulomatous lesions of paratuberculosis-infected bovine intestine
    Juyeon Lee
    Department of Veterinary Anatomy, College of Veterinary Medicine and Applied Radiological Science Research Institute, Jeju National University, Jeju 690 756, Korea
    J Vet Sci 10:177-80. 2009
    ..These findings suggest that galectin-3 is associated with the formation of chronic granulation tissues in bovine paratuberculosis, probably through cell adhesion and anti-apoptosis mechanisms...
  50. pmc Gamma-ray irradiation stimulates the expression of caveolin-1 and GFAP in rat spinal cord: a study of immunoblot and immunohistochemistry
    Meejung Ahn
    Department of Veterinary Medicine, College of Applied Life Sciences, Cheju National University, Jeju 690 756, Korea
    J Vet Sci 7:309-14. 2006
    ..The precise role of caveolin-1 in the spinal cords should be studied further...
  51. doi request reprint Immunohistochemical study of arginase 1 and 2 in various tissues of rats
    Sungyoung Choi
    Laboratory of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Republic of Korea
    Acta Histochem 114:487-94. 2012
    ..These findings indicate that the levels of arginase 1 and 2 varied among organs, suggesting that the arginase isoforms may play organ-specific roles in the urea cycle...
  52. doi request reprint Amelioration of experimental autoimmune encephalomyelitis in Lewis rats treated with fucoidan
    Heechul Kim
    Department of Veterinary Anatomy, College of Veterinary Medicine and Applied Radiological Science Research Institute, Jeju National University, Jeju 690 756, South Korea
    Phytother Res 24:399-403. 2010
    ..The ameliorative effect of fucoidan on clinical paralysis in EAE-affected rats may be mediated, in part, by the suppression of the autoreactive T cell response and inflammatory cytokine production...
  53. ncbi request reprint Expression of phospholipase D isozymes in mouse lungs during postnatal development
    Changjong Moon
    Department of Veterinary Anatomy, Chonnam National University, South Korea
    J Vet Med Sci 71:965-8. 2009
    ..These findings suggest that the increase of PLD expression is associated with pulmonary alveolarization, possibly by involvement in cell proliferation and differentiation during postnatal mouse lung development...
  54. pmc Maturation of bone marrow-derived dendritic cells by a novel β-glucan purified from Paenibacillus polymyxa JB115
    Eun Ju Ko
    College of Veterinary Medicine, Jeju National University, Jeju 690 756, Korea
    J Vet Sci 12:187-9. 2011
    ..These results demonstrate the effect of β-glucan on DC maturation and may increase the use of β-glucan...
  55. pmc Radioprotective effects of fucoidan on bone marrow cells: improvement of the cell survival and immunoreactivity
    Yun Young Byon
    College of Veterinary Medicine, Cheju National University, Jeju 690 756, Korea
    J Vet Sci 9:359-65. 2008
    ..Taken together, our study demonstrated that fucoidan has radioprotective effects on BMCs with respect to cell viability and immunoreactivity. These results may provide valuable information, useful in the field of radiotherapy...
  56. doi request reprint Enzymatic extract from Ecklonia cava induces the activation of lymphocytes by IL-2 production through the classical NF-κB pathway
    Ginnae Ahn
    Department of Marine Life Science, Jeju National University, Jeju, 690 756, Republic of Korea
    Mar Biotechnol (NY) 13:66-73. 2011
    ..Accordingly, our results suggest that ECK increases the production of IL-2 through the activation of NF-κB then induces the proliferation of lymphocytes with the coordinated stimulation of IL-2...
  57. ncbi request reprint Expression of nitric oxide synthase isoforms in the porcine ovary during follicular development
    Heechul Kim
    Department of Veterinary Medicine, Graduate School, Cheju National University, Jeju, Korea
    J Vet Sci 6:97-101. 2005
    ..Taking all of the findings into consideration, the observed differential expression of the three NOS isoforms in the ovary suggests a role for nitric oxide in modulating reproduction in pigs...
  58. ncbi request reprint Increased expression of osteopontin in the heart tissue of Lewis rats with experimental autoimmune myocarditis
    Taekyun Shin
    Department of Veterinary Medicine, Cheju National University, Jeju, Republic of Korea
    J Vet Med Sci 68:379-82. 2006
    ..These findings suggest that OPN is significantly increased in EAM lesions and that OPN mediates the inflammatory process in the course of rat EAM model...
  59. ncbi request reprint 1,2,3,4,6-penta-O-galloyl-beta-D-glucose protects splenocytes against radiation-induced apoptosis in murine splenocytes
    So Jin Bing
    Department of Veterinary Medicine and Applied Radiological Science Research Institute, Jeju National University, Jeju 690 756, South Korea
    Biol Pharm Bull 33:1122-7. 2010
    ..The results presented in this study suggest that PGG has a cytoprotective effect on immune cells exposed to normally damaging amount of radiation. Thus, PGG could be an effective, non-toxic radioprotective agent...
  60. ncbi request reprint Protective effect of phlorotannin components phloroglucinol and eckol on radiation-induced intestinal injury in mice
    Changjong Moon
    College of Veterinary Medicine, Chonnam National University, Gwangju 500 757, South Korea
    Phytother Res 22:238-42. 2008
    ....
  61. pmc Increased phosphorylation of c-Jun NH (2)-terminal protein kinase in the sciatic nerves of Lewis rats with experimental autoimmune neuritis
    Meejung Ahn
    Department of Veterinary Medicine, Cheju National University, Jeju 690 756, Korea
    J Vet Sci 7:13-7. 2006
    ..These findings suggest that JNK phosphorylation is closely associated with the clearance of inflammatory cells as well as the activation of Schwann cells in the EAN affected sciatic nerves...
  62. ncbi request reprint Expression of CD44 adhesion molecule in rat testis with ischemia/reperfusion injury
    Changjong Moon
    Department of Veterinary Medicine, College of Applied Life Science and Applied Radiological Science Research Institute, Cheju National University, Jeju, Republic of Korea
    J Vet Med Sci 68:761-4. 2006
    ....
  63. doi request reprint Immunohistochemical localization of protein kinase C (PKC) beta I in the pig retina during postnatal development
    Chanwoo Jeong
    Laboratory of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, South Korea
    Acta Histochem 114:18-23. 2012
    ....
  64. ncbi request reprint Immunohistochemical localization of galectin-3 in boar testis and epididymis
    Heechul Kim
    Department of Veterinary Medicine, Cheju National University, Jeju 690 756, Republic of Korea
    Acta Histochem 108:481-5. 2006
    ....
  65. doi request reprint Developmental changes affecting lectin binding in the vomeronasal organ of domestic pigs, Sus scrofa
    Junwoo Park
    Laboratory of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, South Korea
    Acta Histochem 114:24-30. 2012
    ..These findings suggest that binding sites of lectins, including those of WGA, UEA-I, DBA, and SBA, increase during development from fetal to postnatal growth, possibly contributing to the increased ability of chemoreception in the pig...
  66. ncbi request reprint Phospholipase D1 is up-regulated in the retina of Lewis rats with experimental autoimmune uveoretinitis
    JongChul Kang
    Department of Veterinary Medicine, College of Agriculture and Life Science, Cheju National University, Jeju, Republic of Korea
    Immunol Invest 34:27-36. 2005
    ....