Shrimati Shetty

Summary

Publications

  1. doi request reprint Acquired hemophilia a: diagnosis, aetiology, clinical spectrum and treatment options
    Shrimati Shetty
    National Institute of Immunohematology ICMR, 13th Floor, KEM Hospital, Parel, Mumbai 400 012, India
    Autoimmun Rev 10:311-6. 2011
  2. doi request reprint Thrombophilic dimension of Budd chiari syndrome and portal venous thrombosis--a concise review
    Shrimati Shetty
    National Institute of Immunohaematology, 13 th Floor, KEM Hospital, Parel, Mumbai 400012, India
    Thromb Res 127:505-12. 2011
  3. doi request reprint Pathophysiology of acquired von Willebrand disease: a concise review
    Shrimati Shetty
    National Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    Eur J Haematol 87:99-106. 2011
  4. doi request reprint Challenges of multiple mutations in individual patients with haemophilia
    Shrimati Shetty
    National Institute of Immunohematology ICMR, KEM Hospital, Parel, Mumbai, India
    Eur J Haematol 86:185-90. 2011
  5. ncbi request reprint Thrombophilia and unexplained pregnancy loss in Indian patients
    Sonal Vora
    National Institute of Immunohaematology ICMR, K E M Hospital, Parel, Mumbai 400012, Maharashtra, India
    Natl Med J India 21:116-9. 2008
  6. doi request reprint Novel mutations in factor IX gene from western India with reference to their phenotypic and haplotypic attributes
    Leera Quadros
    Department of Haemostasis and Thrombosis, National Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    J Pediatr Hematol Oncol 31:157-60. 2009
  7. ncbi request reprint Contribution of natural anticoagulant and fibrinolytic factors in modulating the clinical severity of haemophilia patients
    Shrimati Shetty
    Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    Br J Haematol 138:541-4. 2007
  8. doi request reprint Utility of an exon 14 BslI polymorphism for improved genetic diagnosis of hemophilia A in Indian population
    Preethi Mukundan
    National Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    Prenat Diagn 28:920-2. 2008
  9. doi request reprint Thrombophilic dimension of recurrent fetal loss in Indian patients
    Sonal Vora
    National Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    Blood Coagul Fibrinolysis 19:581-4. 2008
  10. ncbi request reprint Evolution of prenatal diagnostic techniques from phenotypic diagnosis to gene arrays: its likely impact on prenatal diagnosis of hemophilia
    Kanjaksha Ghosh
    Department of Haemostasis, Institute of Immunohaematology, KEM Hospital Campus, Parel, Mumbai 400 012, India
    Clin Appl Thromb Hemost 15:277-82. 2009

Collaborators

  • Kanjaksha Ghosh
  • Dipika Mohanty
  • Susan Idicula-Thomas
  • M Spreafico
  • U Shankarkumar
  • F Peyvandi
  • Navin Pai
  • Sonal Vora
  • Bipin Kulkarni
  • Sucheta Trasi
  • Leera Quadros
  • Leenam Mota
  • Purnima Satoskar
  • Rucha Patil
  • Shahnaz Ali
  • Tejasvita Gaikwad
  • Vivian Lobo
  • Atanu Basu
  • Priyanka Kasatkar
  • Preethi Satish Nair
  • Manasi Vijapurkar
  • Vaibhav S Banait
  • Vinita Salvi
  • Preethi Mukundan
  • Amit Khare
  • Sona Nair
  • Vrinda Kulkarni
  • Cecil Ross
  • Shobha Gangodkar
  • Divija Deshpande
  • Ketaki Ganti
  • Payel Sarkar
  • Preksha Jain
  • M S Sandeep
  • Pravin M Rathi
  • Mukta R Bapat
  • Philip Abraham
  • Anil Pathare

Detail Information

Publications55

  1. doi request reprint Acquired hemophilia a: diagnosis, aetiology, clinical spectrum and treatment options
    Shrimati Shetty
    National Institute of Immunohematology ICMR, 13th Floor, KEM Hospital, Parel, Mumbai 400 012, India
    Autoimmun Rev 10:311-6. 2011
    ..The present review summarizes the diagnostic, aetiological, clinical and treatment aspects of AHA focusing on the recent advances in this area...
  2. doi request reprint Thrombophilic dimension of Budd chiari syndrome and portal venous thrombosis--a concise review
    Shrimati Shetty
    National Institute of Immunohaematology, 13 th Floor, KEM Hospital, Parel, Mumbai 400012, India
    Thromb Res 127:505-12. 2011
    ..Evaluation of an extensive thrombophilia profile is essential for optimal management of patients which is further justified with the availability of specific treatment options for at least some thrombophilia markers...
  3. doi request reprint Pathophysiology of acquired von Willebrand disease: a concise review
    Shrimati Shetty
    National Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    Eur J Haematol 87:99-106. 2011
    ..This report presents a concise review of the pathophysiological mechanisms of AVWD in these various underlying conditions...
  4. doi request reprint Challenges of multiple mutations in individual patients with haemophilia
    Shrimati Shetty
    National Institute of Immunohematology ICMR, KEM Hospital, Parel, Mumbai, India
    Eur J Haematol 86:185-90. 2011
    ....
  5. ncbi request reprint Thrombophilia and unexplained pregnancy loss in Indian patients
    Sonal Vora
    National Institute of Immunohaematology ICMR, K E M Hospital, Parel, Mumbai 400012, Maharashtra, India
    Natl Med J India 21:116-9. 2008
    ..We studied the association of acquired and inherited markers of thrombophilia in a large group of patients with unexplained pregnancy loss...
  6. doi request reprint Novel mutations in factor IX gene from western India with reference to their phenotypic and haplotypic attributes
    Leera Quadros
    Department of Haemostasis and Thrombosis, National Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    J Pediatr Hematol Oncol 31:157-60. 2009
    ..Hemophilia B (HB) is an X-linked recessively inherited bleeding disorder caused by heterogeneous mutations in the factor IX gene...
  7. ncbi request reprint Contribution of natural anticoagulant and fibrinolytic factors in modulating the clinical severity of haemophilia patients
    Shrimati Shetty
    Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    Br J Haematol 138:541-4. 2007
    ..These results indicate a synergistic modulation of bleeding tendency in haemophilia patients by factors in the anticoagulant and fibrinolytic systems...
  8. doi request reprint Utility of an exon 14 BslI polymorphism for improved genetic diagnosis of hemophilia A in Indian population
    Preethi Mukundan
    National Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    Prenat Diagn 28:920-2. 2008
    ....
  9. doi request reprint Thrombophilic dimension of recurrent fetal loss in Indian patients
    Sonal Vora
    National Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    Blood Coagul Fibrinolysis 19:581-4. 2008
    ....
  10. ncbi request reprint Evolution of prenatal diagnostic techniques from phenotypic diagnosis to gene arrays: its likely impact on prenatal diagnosis of hemophilia
    Kanjaksha Ghosh
    Department of Haemostasis, Institute of Immunohaematology, KEM Hospital Campus, Parel, Mumbai 400 012, India
    Clin Appl Thromb Hemost 15:277-82. 2009
    ....
  11. doi request reprint Hereditary thrombophilia in cerebral venous thrombosis: a study from India
    Navin Pai
    National Institute of Immunohaematology, KEM Hospital, Parel, Mumbai, India
    Blood Coagul Fibrinolysis 24:540-3. 2013
    ..Thrombophilia markers accounted for approximately one-fifth of the patients. Death due to CVT has shown remarkable reduction (13%) because of early diagnosis and appropriate anticoagulation...
  12. ncbi request reprint First-trimester prenatal diagnosis in haemophilia A and B families--10 years experience from a centre in India
    Shrimati Shetty
    Institute of Immunohaematology ICMR, Department of Haematology, KEM Hospital, Parel, Mumbai 400 012, India
    Prenat Diagn 26:1015-7. 2006
    ..Only one case of misdiagnosis was detected so far (0.22%), where the diagnosis was based only on the extragenic marker of the factor VIII gene...
  13. doi request reprint Phenotypic and genotypic characterization of Factor VII deficiency patients from Western India
    Leenam Mota
    National Institute of Immunohaematology, 13th floor of KEM Hospital Campus, Parel, Mumbai, 400012, India
    Clin Chim Acta 409:106-11. 2009
    ..Congenital factor VII (FVII) deficiency is a rare coagulation deficiency caused due to defects in the FVII gene...
  14. ncbi request reprint Hypercoagulable state in idiopathic ulcerative colitis: role of hyperhomocysteinemia and hyperfibrinogenemia
    Vaibhav S Banait
    Department of Gastroenterology, King Edward Memorial Hospital, Mumbai 400 012, India
    Indian J Gastroenterol 27:94-8. 2008
    ..Previous reports on hypercoagulable factors in inflammatory bowel diseases involve heterogeneous populations and patients on various medications...
  15. doi request reprint Spectrum of factor IX gene mutations causing haemophilia B from India
    Kanjaksha Ghosh
    Department of Haemostasis and Thrombosis, National Institute of Immunohaematology, 13th Fl KEM Hospital Campus, Parel, Mumbai 400012, India
    Blood Coagul Fibrinolysis 20:333-6. 2009
    ..The spectrum of mutations in haemophilia B patients reported from other parts of India has been compiled and a comprehensive analysis has been presented...
  16. doi request reprint Hereditary protein C deficiency in Indian patients with venous thrombosis
    Navin Pai
    National Institute of Immunohaematology ICMR, KEM Hospital Campus, Parel, Mumbai, 400012, India
    Ann Hematol 91:1471-6. 2012
    ..001). PC deficiency in Indian VT patients can, thus, largely be explained by PROC gene promoter CG polymorphisms; only a small fraction of the patients show specific mutations in PROC gene...
  17. ncbi request reprint Successful pregnancy outcome in women with bad obstetric history and recurrent fetal loss due to thrombophilia: effect of unfractionated heparin and low-molecular weight heparin
    Kanjaksha Ghosh
    Deptartment of Haemostasis, Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    Clin Appl Thromb Hemost 14:174-9. 2008
    ..None of the patients in either group had to interrupt the therapy for any adverse treatment-related complications...
  18. ncbi request reprint Use of a new enzyme-linked immunosorbent assay for the detection of type 2N von Willebrand disease and its prevalence in an Indian population
    Kanjaksha Ghosh
    Institute of Immunohaematology ICMR, KEM Hospital Campus, Parel, Mumbai, India
    Blood Coagul Fibrinolysis 17:7-11. 2006
    ..The simple ELISA technique described here should be available in all routine laboratories in developing countries...
  19. doi request reprint JAK2 mutations across a spectrum of venous thrombosis cases
    Shrimati Shetty
    National Institute of Immunohaematology, KEM Hospital, Parel, Mumbai, India
    Am J Clin Pathol 134:82-5. 2010
    ..The significance of screening for this mutation in nonsplanchnic thrombosis cases needs to be analyzed in a larger series...
  20. doi request reprint Molecular pathology of haemophilia A in Indian patients: identification of 11 novel mutations
    Preethi Satish Nair
    Department of Haemostasis, National Institute of Immunohaematology ICMR, KEM Hospital Campus, Parel, Mumbai 400012, India
    Clin Chim Acta 411:2004-8. 2010
    ..The identification of pathogenic mutations in haemophilia A (HA) patients is important as a basis for genetic diagnosis and also for the assessment of clinical manifestations...
  21. ncbi request reprint Fasting plasma homocysteine levels are increased in young patients with acute myocardial infarction from Western India
    Kanjaksha Ghosh
    Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    Indian Heart J 59:242-5. 2007
    ..In India folic acid deficiency is not uncommon, and subclinical folic acid deficiency is known to cause hyperhomocysteinemia without thrombocytopenia...
  22. doi request reprint A novel ELISA for diagnosis of Glanzmann's thrombasthenia and the heterozygote carriers
    Vivian Lobo
    National Institute of Immunohematology, KEM Hospital Campus, Parel, Mumbai, India
    Ann Hematol 91:917-21. 2012
    ....
  23. ncbi request reprint Mutations in the MCFD2 gene and a novel mutation in the LMAN1 gene in Indian families with combined deficiency of factor V and VIII
    Dipika Mohanty
    Haemostasis Laboratory, Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    Am J Hematol 79:262-6. 2005
    ..The third family did not show mutations in either of the two genes, suggesting that a significant subset of F5F8D cases may be due to additional genes resulting in a similar phenotype...
  24. ncbi request reprint Von Willebrand factor 1 and factor 2 alleles (intron 40) are suitable markers for carrier detection in von Willebrand disease families in the Indian population
    Sucheta Trasi
    Institute of Immunohematology ICMR, KEM Hospital Campus, Parel, Mumbai, India
    Acta Haematol 115:64-7. 2006
    ..The high heterozygosity of the two vWF intron 40 VNTR markers and the simplicity of the technique without much cost being involved suggest the practical feasibility of this technique in developing countries like India...
  25. doi request reprint Novel mutations in GP IIb gene in Glanzmann's thrombasthenia from India
    Manasi Vijapurkar
    Department of Haemostasis and Thrombosis, National Institute of Immunohaematology, Parel, Mumbai, India
    Platelets 20:35-40. 2009
    ..The study thus identifies novel mutations in the GPIIb gene in patients from Western India, implicating the importance of certain amino acids in structure-function correlations as well as enabling prenatal diagnosis in these families...
  26. doi request reprint Influence of CYP2C9 and VKORC1 gene polymorphisms on warfarin dosage, over anticoagulation and other adverse outcomes in Indian population
    Tejasvita Gaikwad
    National Institute of Immunohaematology ICMR, 13th Floor, KEM Hospital, Parel, Mumbai 400012, India
    Eur J Pharmacol 710:80-4. 2013
    ..The variation in therapeutic dosage of warfarin and the associated adverse events across different populations is due to the wide differences in the frequency of these warfarin sensitive alleles...
  27. doi request reprint Anti-phospholipid antibodies and other immunological causes of recurrent foetal loss--a review of literature of various therapeutic protocols
    Shrimati Shetty
    National Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai 400012, India
    Am J Reprod Immunol 62:9-24. 2009
    ..However, most of the immunological theories have not fulfilled the criteria for causality. This is a review of the various immunological causes of RFL and the outcome of different treatment protocols...
  28. doi request reprint Immune response to FVIII in hemophilia A: an overview of risk factors
    Kanjaksha Ghosh
    National Institute of Immunohaematology, 13th Fl, KEM Hospital, Parel, Mumbai 400012, India
    Clin Rev Allergy Immunol 37:58-66. 2009
    ..The modifiable risk factors for inhibitor formation may provide the key to predict and perhaps prevent the formation of inhibitors in hemophilia patients...
  29. ncbi request reprint Prevalence and spectrum of von Willebrand disease from western India
    Sucheta Trasi
    Institute of Immunohaematology, Mumbai, India
    Indian J Med Res 121:653-8. 2005
    ..The present study was thus undertaken to know the prevalence of VWD and its various subtypes in the western part of our country...
  30. ncbi request reprint von Willebrand disease: a laboratory approach
    Sucheta Trasi
    Institute of Haematology ICMR, 7th Floor, Multistoreyed Building, K E M Hospital, Parel, Mumbai 400008, Maharashtra, India
    Natl Med J India 18:78-84. 2005
    ..Apart from congenital VWD, the possibility of acquired VWD should be considered in those with a negative past history of bleeding or in the presence of an underlying disease...
  31. ncbi request reprint Prenatal diagnosis of von Willebrand disease in a family
    Sucheta Trasi
    Institute of Immunohaematology ICMR, KEM Hospital Campus, Parel, Mumbai, Maharashtra, India
    Natl Med J India 18:187-8. 2005
    ..In a subsequent pregnancy, similar investigation revealed a normal foetus. Prenatal diagnosis in families with a diagnosed case of VWD can be used to determine the status of the foetus. The technique is inexpensive...
  32. ncbi request reprint Second trimester antenatal diagnosis in rare coagulation factor deficiencies
    Leenam Mota
    Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    J Pediatr Hematol Oncol 29:137-9. 2007
    ..Follow-up studies were performed 3 to 4 months after delivery and the diagnoses were reconfirmed on these babies by a repeat factor assay for FX and FVII deficiency, respectively...
  33. doi request reprint Spectrum of changes in endogenous thrombin potential due to heritable disorders of coagulation
    Kanjaksha Ghosh
    National Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    Blood Coagul Fibrinolysis 19:577-80. 2008
    ..Endogenous thrombin potential of inherited isolated deficiencies of coagulation factors may thus provide an interesting insight about involvement of the deficient factor(s) at different phases of thrombin generation...
  34. doi request reprint Hemostasis research in India: past, present, and future
    Kanjaksha Ghosh
    National Institute of Immunohaematology, KEM Hospital Campus, Mumbai, India
    Clin Appl Thromb Hemost 18:128-33. 2012
    ....
  35. ncbi request reprint Combination of thrombophilia markers in acute myocardial infarction of the young
    Amit Khare
    Institute of Immunohaematology I C M R, 13th Floor New Building, KEM Hospital, Parel, Mumbai 400 012, India
    Indian J Med Sci 58:381-8. 2004
    ..But, there have been very few studies in India which have investigated some of the thrombophilia markers...
  36. ncbi request reprint Prenatal diagnosis in a haemophilia A family by both factor VIII activity and antigen measurements
    Shrimati Shetty
    Institute of Immunohematology ICMR, 13th Floor, KEM Hospital, Parel, Mumbai 400 012, India
    J Assoc Physicians India 51:916-8. 2003
    ..Here we report antenatal diagnosis in a haemophilia A family performed in the second trimester by measuring both factor VIII:C and factor VIII:Ag in the fetal blood sample...
  37. ncbi request reprint A common G10430A mutation (Gly 60 Ser) in the factor IX gene describes the presence of moderate and mild hemophilia B in the majority of the Gujarati population
    Leera Quadros
    KEM Hospital, Institute of Immunohaematology ICMR, Parel, Mumbai, India
    Ann Hematol 86:377-9. 2007
    ..The direct detection of this G10430A mutation can be used for accurate carrier detection and prenatal diagnosis in mild to moderate factor-IX-deficient patients belonging to the Gujarat state of western India...
  38. ncbi request reprint Chronic synovitis and HLA B27 in patients with severe haemophilia
    Kanjaksha Ghosh
    Institute of Immunohaematology, Floor 13, New Building, KEM Hospital Campus, Parel, 400 012, Mumbai, India
    Lancet 361:933-4. 2003
    ..7], p<0.0001). We conclude that there is a strong association between HLA B27 and chronic synovitis in Indian patients with severe haemophilia and screening in this population could allow treatment and prevention of the complication...
  39. ncbi request reprint Coagulation factor deficiency as a cause of recurrent fetal loss: a red herring!
    Sonal Vora
    Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    Blood Coagul Fibrinolysis 18:571-4. 2007
    ..Despite the concomitant presence of both coagulation factor defect and thrombophilia, fetal loss may be attributed to factor defect that in reality is a red herring, with underlying thrombophilia not being evaluated...
  40. doi request reprint Reduced clinical severity in a mutationally well-characterized cohort of severe hemophilia with associated thrombophilia
    Shrimati Shetty
    Institute of Immunohaematology, KEM Hospital, Parel, India
    Am J Clin Pathol 130:84-7; quiz 146. 2008
    ..Thrombophilia thus modulates the clinical severity of hemophilia as is observed in patients who carry similar mutations...
  41. pmc Elevated procoagulant endothelial and tissue factor expressing microparticles in women with recurrent pregnancy loss
    Rucha Patil
    Department of Haemostasis and Thrombosis, National Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    PLoS ONE 8:e81407. 2013
    ..This study aims to analyze the significance of procoagulant MPs in women suffering from unexplained recurrent pregnancy loss(RPL), and characterize their cellular origin...
  42. doi request reprint Bone health in persons with haemophilia: a review
    Kanjaksha Ghosh
    National Institute of Immunohaematology, KEM Hospital, Parel, Mumbai, India
    Eur J Haematol 89:95-102. 2012
    ..This review summarises the prevalence, plausible mechanisms and management options of this important morbidity in PWH...
  43. doi request reprint Cause of deep venous thrombosis and pulmonary embolism in young patients from India as compared with other ethnic groups
    Navin Pai
    National Institute of Immunohematology, Hospital Campus, Parel, Mumbai, India
    Blood Coagul Fibrinolysis 23:257-61. 2012
    ..0001). This can be explained by different inherited and environment risk factors between these three populations...
  44. doi request reprint Epidemiology, diagnosis, and management of von Willebrand disease in India
    Kanjaksha Ghosh
    National Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    Semin Thromb Hemost 37:595-601. 2011
    ..This is likely to tilt the ratios of different VWD types, and VWD is likely to emerge as the most common of all coagulation disorders in the near future...
  45. ncbi request reprint A comprehensive screening analysis of antiphospholipid antibodies in Indian women with fetal loss
    Sonal Vora
    Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai 400012, India
    Eur J Obstet Gynecol Reprod Biol 137:136-40. 2008
    ..The present study was aimed at a comprehensive analysis of acquired thrombophilia in a large series of Indian women with fetal loss...
  46. ncbi request reprint Implications of human genome and modern cell biology research in management of cardiovascular diseases
    Kanjaksha Ghosh
    Institute of Immunohaematology, KEM Hospital, Parel, Mumbai
    Indian Heart J 57:270-3. 2005
  47. doi request reprint Differences in etiological and clinical manifestations in upper extremity and lower limb deep venous thrombosis patients from India
    Navin Pai
    National Institute of Immunohaematology, KEM Hospital, Parel, Mumbai, India
    Clin Appl Thromb Hemost 16:698-700. 2010
    ..We conclude that the topology of thrombosis in deep vein thrombosis (DVT) patients in India is different from that of the Western countries...
  48. ncbi request reprint Glanzmann's thrombasthenia: updated
    Sona Nair
    Institute of Immunohaematology I C M R, 13th Floor, K E M Hospital Campus, Parel, Mumbai 400 012, India
    Platelets 13:387-93. 2002
    ..Nowadays the less direct method of PLA1 typing (determination of the levels of platelet antigen) of the foetal platelets as early as 16 weeks of intrauterine life can be used for prenatal diagnosis of GT...
  49. doi request reprint Delayed vitamin K deficiency as a cause of bleeding: still a concern in the 21st century!
    Priyanka Kasatkar
    National Institute of Immunohaematology, KEM Hospital, Parel, Mumbai, India
    Blood Coagul Fibrinolysis 21:608-10. 2010
    ..VKDB is not an uncommon phenomenon and should be considered in the differential diagnosis of a child with bleeding diathesis...
  50. ncbi request reprint An ELISA assay for the detection of factor VIII antibodies - comparison with the conventional Bethesda assay in a large cohort of haemophilia samples
    Shrimati Shetty
    Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai, India
    Acta Haematol 109:18-22. 2003
    ..5 BU/ml) but was still positive for the ELISA assay. The ELISA thus described had a specificity of 97.8% and a sensitivity of 100% when tested against a large cohort of haemophilia A samples...
  51. ncbi request reprint Blood coagulation in falciparum malaria--a review
    Kanjaksha Ghosh
    Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai 400 012, India
    Parasitol Res 102:571-6. 2008
    ..Thus, in severe falciparum malaria, there is activation of blood coagulation system along with thrombocytopaenia, even before widespread DIC and coagulation failure occur...
  52. ncbi request reprint Comparison of four commercially available activated partial thromboplastin time reagents using a semi-automated coagulometer
    Shrimati Shetty
    Institute of Immunohaematology Indian Council of Medical Research, KEM Hospital, Parel, Mumbai, India
    Blood Coagul Fibrinolysis 14:493-7. 2003
    ..Some reagents showed abnormal aPTT results in mild cases of factor VIII and factor IX deficiency without producing a large number of falsely prolonged aPTT with normal plasma...
  53. doi request reprint Molecular pathology of Bernard-Soulier syndrome in Indian patients
    Shahnaz Ali
    Department of Haemostasis and Thrombosis, National Institute of Immunohaematology, 13th Floor, KEM Hospital, Parel, Mumbai 400012, Maharashtra, India
    Platelets 24:571-3. 2013
    ..Cys24Arg) in two patients in GPIX gene. The molecular basis of BSS patients presented here shows the heterogeneity of this disorder in Indian patients besides providing a basis for genetic diagnosis of affected families. ..
  54. doi request reprint Role of microparticles in recurrent miscarriages and other adverse pregnancies: a review
    Shrimati Shetty
    National Institute of Immunohaematology ICMR, 13th Floor, KEM Hospital, Parel, Mumbai, India
    Eur J Obstet Gynecol Reprod Biol 169:123-9. 2013
    ....
  55. doi request reprint Dengue virus infection of SK Hep1 cells: inhibition of in vitro angiogenesis and altered cytomorphology by expressed viral envelope glycoprotein
    Atanu Basu
    National Institute of Virology, Pune, India National Institute of Immunohaematology, KEM Hospital, Mumbai, India
    FEMS Immunol Med Microbiol 62:140-7. 2011
    ....