Association between C282Y and H63D mutations of the HFE gene with hepatocellular carcinoma in European populations: a meta-analysisFei Jin
Department of Gastroenterology, Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai 200032, China
J Exp Clin Cancer Res 29:18. 2010
..To clarify the relationship between C282Y and H63D mutations and HCC, a meta-analysis including nine studies (1102 HCC cases and 3766 controls, mainly came from European populations) was performed...
High hepatitis B viral load predicts recurrence of small hepatocellular carcinoma after curative resectionLi Shuai Qu
Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai 200032, China
J Gastrointest Surg 14:1111-20. 2010
..001, HR 4.129). HBV DNA level > or = 4 log(10) copies/mL at the time of resection was the most important risk factor for recurrence. Postoperative IFN-alpha treatment significantly decreased the recurrence risk after resection...
- Effect of interferon-γ and tumor necrosis factor-α on hepatitis B virus following lamivudine treatment
Hong Shi
Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
World J Gastroenterol 18:3617-22. 2012
..To evaluate anti-hepatitis B virus (HBV) activity and cytotoxicity of interferon-γ (IFN-γ) and tumor necrosis factor-α (TNF-α) following lamivudine treatment of HepG2.2.15 cells...
- Interferon-α therapy after curative resection prevents early recurrence and improves survival in patients with hepatitis B virus-related hepatocellular carcinoma
Li Shuai Qu
Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, China
J Surg Oncol 102:796-801. 2010
..A retrospective cohort study was conducted to investigate the effect of interferon-α (IFN-α) therapy after curative resection on survival and recurrence in patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC)...
MTHFR polymorphisms and pancreatic cancer risk: lack of evidence from a meta-analysisLei Li
Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai, China
Asian Pac J Cancer Prev 13:2249-52. 2012
..Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms have been reported to be associated with pancreatic cancer, but the published studies had yielded inconsistent results.We therefore performed the present meta-analysis...
- Role of the microenvironment in hepatocellular carcinoma development and progression
Sheng Di Wu
Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai 200032, PR China
Cancer Treat Rev 38:218-25. 2012
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- Evaluation of the association studies of single nucleotide polymorphisms and hepatocellular carcinoma: a systematic review
Fei Jin
Department of Gastroenterology, Shanghai Xuhui Central Hospital, Shanghai, China
J Cancer Res Clin Oncol 137:1095-104. 2011
..There was no systematic review summarized the results of these association studies of candidate SNPs and HCC to date. In order to summarize the results of the association studies, we conducted a concise systematic review...
- Tumour necrosis factor 308 polymorphisms and hepatocellular carcinoma risk: a meta-analysis
Yan Mei Guo
Department of Gastroenterology, Zhongshan Hospital, Shanghai Medical College, Fudan University, Fenglin Road 180, Shanghai 200032, China
Hepatogastroenterology 57:926-31. 2010
..To investigate the association of the common polymorphisms comprehensively defining the genetic variability of the TNFA-308G > A with HCC risk...
- Combined pre-S deletion and core promoter mutations related to hepatocellular carcinoma: A nested case-control study in China
Li Shuai Qu
Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai Qidong Liver Cancer Institute, Qidong, Jiangsu Province, China
Hepatol Res 41:54-63. 2011
..Combination of pre-S deletion and core promoter mutations increased the risk of HCC...
- Significance of the balance between regulatory T (Treg) and T helper 17 (Th17) cells during hepatitis B virus related liver fibrosis
Jing Li
Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai, China
PLoS ONE 7:e39307. 2012
..Here, it is postulated that the balance between regulatory T (Treg) cells and T helper 17 (Th17) cells as an indicator of inflammation may predict fibrosis progression of HBV-LF...
- Overexpression of Smad ubiquitin regulatory factor 2 suppresses transforming growth factor-β mediated liver fibrosis
Yu Cai
Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai, China
J Dig Dis 13:327-34. 2012
..To determine the function of Smad ubiquitin regulatory factor 2 (Smurf2) on the development of liver fibrosis and cirrhosis...
- Differentiation of autoimmune pancreatitis with pancreatic carcinoma remains a challenge to physicians
Pei Li Gong
Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai, China
J Dig Dis 13:267-73. 2012
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- The power and the promise of liver cancer stem cell markers
Li li Liu
Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai, People s Republic of China
Stem Cells Dev 20:2023-30. 2011
..From our point of view, selecting HCC tissue samples from patients with different prognoses and detecting expression patterns of marker combinations may be a new method to identify new and unique markers...
- A case-control study of the relationship between hepatitis B virus DNA level and risk of hepatocellular carcinoma in Qidong, China
Tao Tao Liu
Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
World J Gastroenterol 14:3059-63. 2008
..To investigate the role of hepatitis B virus (HBV) replication in the development of hepatocellular carcinoma (HCC), a nested case-control study was performed to study the relationship between HBV DNA level and risk of HCC...
