S K Sharma

Summary

Publications

  1. pmc Progressive multifocal leucoencephalopathy in HIV/AIDS: observational study from a tertiary care centre in northern India
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 138:72-7. 2013
  2. ncbi request reprint Clinical profile & predictors of poor outcome of adult HIV-tuberculosis patients in a tertiary care centre in north India
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 139:154-60. 2014
  3. pmc Prevalence of metabolic syndrome in a north Indian hospital-based population with obstructive sleep apnoea
    Swastik Agrawal
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 134:639-44. 2011
  4. pmc Comparative evaluation of GenoType MTBDRplus line probe assay with solid culture method in early diagnosis of multidrug resistant tuberculosis (MDR-TB) at a tertiary care centre in India
    Raj N Yadav
    Department of Internal Medicine Division of Research for Pulmonary, Critical Care and Sleep Medicine, All India Institute of Medical Sciences, New Delhi, India
    PLoS ONE 8:e72036. 2013
  5. doi request reprint Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV-negative people at risk of active TB
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Cochrane Database Syst Rev 7:CD007545. 2013
  6. pmc Efficacy and safety of thrice weekly DOTS in tuberculosis patients with and without HIV co-infection: an observational study
    Richa Vashishtha
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
    BMC Infect Dis 13:468. 2013
  7. pmc Early versus delayed initiation of antiretroviral therapy for Indian HIV-Infected individuals with tuberculosis on antituberculosis treatment
    Sanjeev Sinha
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India
    BMC Infect Dis 12:168. 2012
  8. pmc Contribution of medical colleges to tuberculosis control in India under the Revised National Tuberculosis Control Programme (RNTCP): lessons learnt & challenges ahead
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 137:283-94. 2013
  9. pmc HIV & immune reconstitution inflammatory syndrome (IRIS)
    Surendra K Sharma
    Department of Internal Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 134:866-77. 2011
  10. pmc Rare manifestations of sarcoidosis in modern era of new diagnostic tools
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 135:621-9. 2012

Collaborators

Detail Information

Publications84

  1. pmc Progressive multifocal leucoencephalopathy in HIV/AIDS: observational study from a tertiary care centre in northern India
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 138:72-7. 2013
    ..Little is known about the epidemiology and disease course of these patients from India. This study was aimed to determine the frequency of PML in patients with HIV/AIDS, and the clinical features and survival of these patients...
  2. ncbi request reprint Clinical profile & predictors of poor outcome of adult HIV-tuberculosis patients in a tertiary care centre in north India
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 139:154-60. 2014
    ..This study was done to assess the frequency and pattern of TB, outcome of anti-tuberculosis treatment, and the factors related to poor outcome of TB treatment in adult patients with HIV infection...
  3. pmc Prevalence of metabolic syndrome in a north Indian hospital-based population with obstructive sleep apnoea
    Swastik Agrawal
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 134:639-44. 2011
    ..We investigated the prevalence of MS and its components in a cross-sectional study in patients with and without OSA in a hospital-based population of a tertiary health care centre in New Delhi, India...
  4. pmc Comparative evaluation of GenoType MTBDRplus line probe assay with solid culture method in early diagnosis of multidrug resistant tuberculosis (MDR-TB) at a tertiary care centre in India
    Raj N Yadav
    Department of Internal Medicine Division of Research for Pulmonary, Critical Care and Sleep Medicine, All India Institute of Medical Sciences, New Delhi, India
    PLoS ONE 8:e72036. 2013
    ....
  5. doi request reprint Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV-negative people at risk of active TB
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Cochrane Database Syst Rev 7:CD007545. 2013
    ..Rifampicin or rifamycin-combination treatments are shorter and may result in higher completion rates...
  6. pmc Efficacy and safety of thrice weekly DOTS in tuberculosis patients with and without HIV co-infection: an observational study
    Richa Vashishtha
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
    BMC Infect Dis 13:468. 2013
    ..The present study sets out to compare TB treatment outcomes in these two groups in the Indian national programme, which currently involves thrice-weekly therapy for all, regardless of HIV status...
  7. pmc Early versus delayed initiation of antiretroviral therapy for Indian HIV-Infected individuals with tuberculosis on antituberculosis treatment
    Sanjeev Sinha
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India
    BMC Infect Dis 12:168. 2012
    ....
  8. pmc Contribution of medical colleges to tuberculosis control in India under the Revised National Tuberculosis Control Programme (RNTCP): lessons learnt & challenges ahead
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 137:283-94. 2013
    ....
  9. pmc HIV & immune reconstitution inflammatory syndrome (IRIS)
    Surendra K Sharma
    Department of Internal Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 134:866-77. 2011
    ....
  10. pmc Rare manifestations of sarcoidosis in modern era of new diagnostic tools
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 135:621-9. 2012
    ..We sought to study the rare clinical and radiological manifestations (<5%) in patients with sarcoidosis...
  11. doi request reprint Outcomes of Category III DOTS treatment in immunocompetent patients with tuberculosis pleural effusion
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Int J Tuberc Lung Dis 16:1505-9. 2012
    ....
  12. ncbi request reprint Relevance of latent TB infection in areas of high TB prevalence
    Surendra K Sharma
    Department of Internal Medicine, All India Institute of Medical Sciences, New Delhi, India
    Chest 142:761-73. 2012
    ..There is ample space for further research in these countries, whose outcomes may strengthen future national guidelines...
  13. pmc Challenges in the diagnosis & treatment of miliary tuberculosis
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 135:703-30. 2012
    ..However, sparse data are available from randomized controlled trials to define the optimum regimen and duration of treatment in patients with drug-sensitive as well as drug-resistant miliary TB, including those with HIV/AIDS...
  14. doi request reprint CPAP for the metabolic syndrome in patients with obstructive sleep apnea
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    N Engl J Med 365:2277-86. 2011
    ..It is unclear whether treatment of obstructive sleep apnea syndrome with continuous positive airway pressure (CPAP) would modify these outcomes...
  15. ncbi request reprint Distribution of CCR2 polymorphism in HIV-1-infected and healthy subjects in North India
    G Kaur
    Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    Int J Immunogenet 34:153-6. 2007
    ....
  16. ncbi request reprint Prediction of obstructive sleep apnea in patients presenting to a tertiary care center
    S K Sharma
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
    Sleep Breath 10:147-54. 2006
    ..7, 89.1, and 84.5%, respectively. BMI, male gender, SI, and ChI are independent predictors of OSA. Diagnostic model derived from these parameters is useful for predicting presence of OSA and screening subjects for PSG...
  17. ncbi request reprint Validation of the modified Berlin questionnaire to identify patients at risk for the obstructive sleep apnoea syndrome
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 124:281-90. 2006
    ..The present study was undertaken to test the utility of modified Berlin questionnaire for risk categorization of OSA in Indian setting...
  18. ncbi request reprint DOTS at a tertiary care center in northern India: successes, challenges and the next steps in tuberculosis control
    Mohammad Tahir
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 123:702-6. 2006
    ..We present a brief report on the status of a DOTS center being run at a large tertiary care center in northern India for almost four years (2001-2005)...
  19. doi request reprint Risk and outcome of multidrug-resistant tuberculosis: vitamin D receptor polymorphisms and serum 25(OH)D
    J Rathored
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Int J Tuberc Lung Dis 16:1522-8. 2012
    ..All India Institute of Medical Sciences and Rajan Babu Institute of Pulmonary Medicine and Tuberculosis, New Delhi, India...
  20. ncbi request reprint Tubercular oesophagocutaneous fistula
    B N Vinodh
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    Indian J Chest Dis Allied Sci 48:209-11. 2006
    ..A case of oesophageal tuberculosis complicated by an oesophagocutaneous fistual is reported. We subsequently review the literature of this exceedingly rare condition...
  21. ncbi request reprint A prospective study of sensitivity and specificity of adenosine deaminase estimation in the diagnosis of tuberculosis pleural effusion
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi
    Indian J Chest Dis Allied Sci 43:149-55. 2001
    ..From this study it is concluded that, using 100 IU/L as the cut-off, it is possible to avoid pleural biopsy to ascertain the diagnosis of TB in as much as 40% of the patients...
  22. ncbi request reprint Human Toll-like receptor 4 polymorphisms TLR4 Asp299Gly and Thr399Ile influence susceptibility and severity of pulmonary tuberculosis in the Asian Indian population
    N Najmi
    Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, New Delhi, India
    Tissue Antigens 76:102-9. 2010
    ..The present data suggest that TLR4 substitutions at residues 299 and 399 are associated with pulmonary TB, particularly, the most severe disease...
  23. ncbi request reprint The use of diagnostic bronchoscopy in lung cancer
    S K Sharma
    All India Institute of Medical Sciences, New Delhi
    Natl Med J India 5:162-6. 1992
    ..Patients with non-resolving pneumonia, pleural effusion, metastatic disease and non-specific lesions on chest X-ray should receive a low priority for bronchoscopy...
  24. pmc Spectrum of clinical disease in a series of 135 hospitalised HIV-infected patients from north India
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    BMC Infect Dis 4:52. 2004
    ..The objective of this study was to document the spectrum and determine the frequency of various opportunistic infections (OIs) and non-infectious opportunistic diseases, in hospitalised HIV-infected patients from north India...
  25. ncbi request reprint Structural and functional abnormalities in lungs in patients with achalasia
    G K Makharia
    Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi, India
    Neurogastroenterol Motil 21:603-8, e20. 2009
    ..3%) each]. There was a significant association between presence of regurgitation and dilatation of oesophagus (P = 0.032). More than half (53.3%) of patients with achalasia have structural and/or functional abnormalities in lungs...
  26. ncbi request reprint HIV seropositivity among adult tuberculosis patients in Delhi
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Chest Dis Allied Sci 42:157-60. 2000
    ..As the HIV infection is making rapid in-roads in India, it is suggested that continuous HIV sero-surveillance should be done in patients with tuberculosis...
  27. ncbi request reprint Body-mass index, waist-size, waist-hip ratio and cardiovascular risk factors in urban subejcts
    R Gupta
    Department of Medicine, Monilek Hospital and Research Centre, Jawahar Nagar, Jaipur 302004, India
    J Assoc Physicians India 55:621-7. 2007
    ..To determine association of obesity, measured by body-mass index (BMI), waist-size or waist-hip ratio (WHR), with multiple risk factors in an urban Indian population we performed an epidemiological study...
  28. ncbi request reprint Obesity, and not obstructive sleep apnea, is responsible for increased serum hs-CRP levels in patients with sleep-disordered breathing in Delhi
    S K Sharma
    Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Sleep Med 9:149-56. 2008
    ..The present study was conducted to evaluate serum levels of high-sensitivity C-reactive protein (hs-CRP) in newly diagnosed patients with obstructive sleep apnea (OSA)...
  29. ncbi request reprint A stepped approach for prediction of obstructive sleep apnea in overtly asymptomatic obese subjects: a hospital based study
    S K Sharma
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Sleep Med 5:351-7. 2004
    ..Polysomnography (PSG) is a costly and time-consuming investigation. Since it is not feasible to subject all obese individuals to PSG, it is useful to define predictors of OSA among these subjects...
  30. doi request reprint Status of TIM-1 exon 4 haplotypes and CD4+T cell counts in HIV-1 seroprevalent North Indians
    Gaurav Sharma
    Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
    Hum Immunol 74:163-5. 2013
    ..02). A comparison of CD4+T counts between D3-A individuals on ART or ART naïve did not show any significant difference plausibly due to confounding nature of ART and other factors...
  31. ncbi request reprint Angiotensin converting enzyme genotype affects development and course of sarcoidosis in Asian Indians
    Mohammad Tahir
    Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Sarcoidosis Vasc Diffuse Lung Dis 24:106-12. 2007
    ..Present study was designed to evaluate the relationship between I/D polymorphism and susceptibility to develop sarcoidosis and its effect on SACE activity and disease course in Asian Indian patients with sarcoidosis...
  32. ncbi request reprint Persistently high HIV seroprevalence among adult tuberculosis patients at a tertiary care centre in Delhi
    P Piramanayagam
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
    Indian J Med Res 125:163-7. 2007
    ..This study was designed to estimate HIV seroprevalence among tuberculosis patients presenting to tertiary care centre in Delhi...
  33. ncbi request reprint Predictors of development and outcome in patients with acute respiratory distress syndrome due to tuberculosis
    S K Sharma
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, All India Institute of Medical Sciences, New Delhi, India
    Int J Tuberc Lung Dis 10:429-35. 2006
    ..To study the predictors of development and determinants of outcome in patients with acute respiratory distress syndrome (ARDS) due to tuberculosis (TB)...
  34. ncbi request reprint Polymorphism in the CCR5 gene promoter and HIV-1 infection in North Indians
    Gurvinder Kaur
    Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, New Delhi, India
    Hum Immunol 68:454-61. 2007
    ..Further studies are required to confirm these findings and understand the effect of CCR5 polymorphisms on the outcome of HIV-1 infection...
  35. ncbi request reprint Angiotensin-converting enzyme gene polymorphism in north Indian population with obstructive sleep apnea
    H K Mishra
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Sleep Breath 17:1029-37. 2013
    ..A deletion of 287-bp Alu repeat of angiotensin-converting enzyme (ACE) insertion/deletion (I/D) gene is associated with hypertension...
  36. ncbi request reprint Obesity, and not obstructive sleep apnea, is responsible for metabolic abnormalities in a cohort with sleep-disordered breathing
    S K Sharma
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Sleep Med 8:12-7. 2007
    ..To assess the profile of metabolic abnormalities in subjects with obstructive sleep apnea (OSA)...
  37. ncbi request reprint Diagnostic accuracy of ascitic fluid IFN-gamma and adenosine deaminase assays in the diagnosis of tuberculous ascites
    S K Sharma
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    J Interferon Cytokine Res 26:484-8. 2006
    ..Because both material and human costs of the ADA assay are far less than those of the IFN-gamma assay, the former is probably the most appropriate diagnostic test for analysis of peritoneal fluid in resource- limited settings...
  38. ncbi request reprint Immune reconstitution inflammatory syndrome manifesting as disseminated tuberculosis, deep venous thrombosis, encephalopathy and myelopathy
    Mohammad Tahir
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Chest Dis Allied Sci 50:363-4. 2008
    ..In addition to HAART and antituberculosis treatment (ATT), the patient was given non-steroidal anti-inflammatory drugs, oral vitamin B12 and heparin, which was later switched to oral warfarin...
  39. ncbi request reprint High resolution CT (HRCT) in miliary tuberculosis (MTB) of the lung: Correlation with pulmonary function tests & gas exchange parameters in north Indian patients
    S N J Pipavath
    Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 126:193-8. 2007
    ..We made an attempt in this study to identify patterns of pulmonary MTB on HRCT and to correlate the HRCT disease extent with pulmonary function tests (PFT) and gas exchange analysis (GEA)...
  40. ncbi request reprint Immunogenetics of mycobacterial infections in the North Indian population
    M Singh
    Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, New Delhi 110029, India
    Tissue Antigens 69:228-30. 2007
    ....
  41. ncbi request reprint A clinical prediction rule to identify patients with tuberculosis at high risk for HIV co-infection
    S K Sharma
    Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 130:51-7. 2009
    ..We sought to derive and validate a clinical prediction rule, based on clinical and laboratory parameters, to identify patients at high risk for HIV co-infection among those treated for active TB...
  42. ncbi request reprint Role of acute viral hepatitis as a confounding factor in antituberculosis treatment induced hepatotoxicity
    Pawan Sarda
    Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 129:64-7. 2009
    ..Acute viral hepatitis (AVH) is an important confounding reason which clinically, biochemically and histologically mimics DIH...
  43. pmc HIV associated renal disease: a pilot study from north India
    Vijay Gupta
    Department of Nephrology, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 137:950-6. 2013
    ..HIV/AIDS patients may have renal involvement also, however, Indian data are sparse. The present study was done to find the spectrum of renal diseases in HIV/AIDS patients in north India...
  44. ncbi request reprint Antituberculosis drugs and hepatotoxicity
    S K Sharma
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Infect Genet Evol 4:167-70. 2004
  45. ncbi request reprint Scientific basis of directly observed treatment, short-course (DOTS)
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029
    J Indian Med Assoc 101:157-8, 166. 2003
    ..Patients with HIV infection and TB disease respond well to antituberculosis treatment if they are given short-course chemotherapy in the programme of DOTS...
  46. doi request reprint Metabolic and body composition changes after six months of highly active antiretroviral therapy in northern Indian patients
    V Gupta
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Int J STD AIDS 22:46-9. 2011
    ..Larger studies across India with long-term follow-up periods are required to confirm these preliminary findings. We also recommend that frequent biochemical monitoring should be performed in such patients...
  47. ncbi request reprint Significance of haematological manifestations in patients with tuberculosis
    K J Singh
    Department of Medicine, All India Institute of Medical Sciences, New Delhi
    J Assoc Physicians India 49:788, 790-4. 2001
    ....
  48. ncbi request reprint Idiopathic pulmonary haemosiderosis: two case reports
    B N Vinodh
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    Indian J Chest Dis Allied Sci 48:75-7. 2006
    ..An extensive diagnostic work-up is needed to exclude other causes of DAH. We report two cases of idiopathic pulmonary haemosiderosis who responded well to treatment with oral glucocorticoids...
  49. ncbi request reprint Multidrug-resistant tuberculosis
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, D II 23, Ansari Nagar, New Delhi 110 029, India
    Indian J Med Res 120:354-76. 2004
    ..In certain areas, currently available programme approach may not be adequate and innovative approaches such as DOTS-plus may have to be employed to effectively control MDR-TB...
  50. ncbi request reprint Reversal of subclinical adrenal insufficiency through antituberculosis treatment in TB patients: a longitudinal follow up
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
    Indian J Med Res 122:127-31. 2005
    ..We studied the effect of antituberculosis treatment (ATT) with respect to reversal of the adrenal insufficiency, as assessed by response to standard dose adrenocorticotropin (ACTH) stimulation test in TB patients...
  51. ncbi request reprint Clinical characteristics, pulmonary function abnormalities and outcome of prednisolone treatment in 106 patients with sarcoidosis
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi
    J Assoc Physicians India 49:697-704. 2001
    ..A high index of clinical suspicion and histopathological confirmation early in the illness are required to ascertain the diagnosis lest these patients will get treated as tuberculosis with potentially hepatotoxic drugs...
  52. ncbi request reprint Genetic polymorphisms of CYP2E1 and GSTM1 loci and susceptibility to anti-tuberculosis drug-induced hepatotoxicity
    S K Sharma
    Departments of Internal Medicine, and Biostatistics, All India Institute of Medical Sciences, New Delhi, India
    Int J Tuberc Lung Dis 18:588-93. 2014
    ..Host genetic factors that influence predisposition to anti-tuberculosis drug-induced hepatotoxicity (DIH) are not clear in the Indian population...
  53. doi request reprint Correlation of plasma anti-tuberculosis drug levels with subsequent development of hepatotoxicity
    A Satyaraddi
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Int J Tuberc Lung Dis 18:188-95, i-iii. 2014
    ..To compare the free and total plasma drug concentrations of rifampicin (RMP), isoniazid and pyrazinamide in subjects with or without anti-tuberculosis drug-induced hepatotoxicity (DIH)...
  54. ncbi request reprint Pleural fluid interferon-gamma and adenosine deaminase levels in tuberculosis pleural effusion: a cost-effectiveness analysis
    S K Sharma
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    J Clin Lab Anal 19:40-6. 2005
    ..In developing countries, where TB is rampant and cost is a major concern, pleural fluid IFN-gamma estimation does not seem to be a cost-effective investigation method for differentiating TB from non-TB pleural effusion...
  55. pmc Neurological picture. Multiple ring enhancing lesions in brain MRI of a patient with AIDS
    Mohammad Tahir
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    J Neurol Neurosurg Psychiatry 78:526. 2007
  56. ncbi request reprint Radiological manifestations of splenic tuberculosis: a 23-patient case series from India
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi
    Indian J Med Res 125:669-78. 2007
    ..The range of radiological manifestations of splenic TB is poorly described. Here, we review the ultrasonographic and computed tomographic (CT) images of 23 cases from two large tertiary care centers in India...
  57. ncbi request reprint DOTS centre at a tertiary care teaching hospital: lessons learned and future directions
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Chest Dis Allied Sci 46:251-6. 2004
    ..In this communication, we describe the experience of establishing a DOTS centre at India's premier medical institute and discuss the lessons learned...
  58. ncbi request reprint HIV-TB co-infection: epidemiology, diagnosis & management
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, India
    Indian J Med Res 121:550-67. 2005
    ..Timely institution of antituberculosis treatment using the directly observed treatment, short-course (DOTS) strategy and HAART markedly improves the outcome of HIV-infected patients with TB...
  59. pmc Prevalence of HIV Drug Resistance Mutations in HIV Type 1 Isolates in Antiretroviral Therapy Naïve Population from Northern India
    S Sinha
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
    AIDS Res Treat 2012:905823. 2012
    ..Conclusion. Our study shows that primary HIVDR mutations have a prevalence of 2.9% among ART-naive chronic HIV-1 infected individuals...
  60. ncbi request reprint Wegener's granulomatosis in India: clinical features, treatment and outcome of twenty-five patients
    A Kumar
    Department of Medicine, All India Institute of Medical Sciences, New Delhi
    Indian J Chest Dis Allied Sci 43:197-204. 2001
    ..To report our clinical experience on Wegener's granulomatosis (WG)...
  61. ncbi request reprint Bilateral adrenal abscesses and skin lesions in an immunocompetent patient
    S K Sharma
    Department of Medicine, India Institute of Medical Sciences, New Delhi, India
    Lancet Infect Dis 5:126. 2005
  62. ncbi request reprint Uncommon manifestations of sarcoidosis
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
    J Assoc Physicians India 52:210-4. 2004
    ..To study the uncommon manifestations in patients of sarcoidosis...
  63. ncbi request reprint Extrapulmonary tuberculosis
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, D II 23, Ansari Nagar, New Delhi 110 029, India
    Indian J Med Res 120:316-53. 2004
    ..Further research is required for evolving the most suitable treatment regimens, optimal duration of treatment and safety when used with highly active antiretroviral treatment (HAART)...
  64. pmc In vitro assessment of drug resistance in Plasmodium falciparum in five States of India
    Anupkumar R Anvikar
    National Institute of Malaria Research NIMR, ICMR, New Delhi, India
    Indian J Med Res 135:494-9. 2012
    ..This study was aimed at determining the in vitro sensitivity of P. falciparum isolates to antimalarials...
  65. ncbi request reprint Clinical and genetic risk factors for the development of multi-drug resistant tuberculosis in non-HIV infected patients at a tertiary care center in India: a case-control study
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Infect Genet Evol 3:183-8. 2003
    ..2; 95% CI [2.1-31.3]) as independent predictors of MDR-TB. Our results suggest that a combination of clinical and immunogenetic parameters could provide better information on drug resistance in tuberculosis with implications in therapy...
  66. ncbi request reprint Fibreoptic bronchoscopy in the diagnosis of sputum smear-negative pulmonary tuberculosis: current status
    Alladi Mohan
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India
    Indian J Chest Dis Allied Sci 50:67-78. 2008
    ..Proper precautions must be followed to disinfect the bronchoscope in between use so as to minimise the risk of nosocomial transmission of infection...
  67. ncbi request reprint A young man with rectal polyps
    S K Sharma
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, All India Institute of Medical Sciences, New Delhi, India
    Lancet Infect Dis 4:556. 2004
  68. ncbi request reprint Video assisted thoracoscopic surgery (VATS) in the diagnosis of intrathoracic pathology: initial experience
    A Kumar
    Department of Surgery, All India Institute of Medical Sciences, New Delhi
    Indian J Chest Dis Allied Sci 41:5-13. 1999
    ..We conclude that video-assisted thoracoscopy is an excellent diagnostic tool to confirm tissue diagnosis in patients with undiagnosed chest diseases...
  69. doi request reprint Ophthalmic manifestations of HIV infections in India in the era of HAART: analysis of 100 consecutive patients evaluated at a tertiary eye care center in India
    Sujit Gharai
    Dr Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India
    Ophthalmic Epidemiol 15:264-71. 2008
    ..To evaluate ophthalmic manifestations in patients with Human Immunodeficiency Virus (HIV) infection in the era of highly active antiretroviral therapy (HAART) at the apex institute for eye healthcare in India...
  70. pmc Evaluation of efficacy and safety of fixed dose lovastatin and niacin(ER) combination in asian Indian dyslipidemic patients: a multicentric study
    Manoj Sharma
    Clinical Research Division, Panacea Biotec Ltd, New Delhi, India
    Vasc Health Risk Manag 2:87-93. 2006
    ..Satisfactory safety and tolerability profile in this population was also demonstrated...
  71. ncbi request reprint Systemic cutaneous amyloidosis
    R Gupta
    Department of Medicine, All India Institute of Medicine Sciences, New Delhi
    J Assoc Physicians India 53:119. 2005
  72. ncbi request reprint Immune reconstitution inflammatory syndrome in a patient with cryptococcal lymphadenitis as the first presentation of acquired immunodeficiency syndrome
    M Tahir
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    J Postgrad Med 53:250-2. 2007
    ..HIV infected patients having opportunistic co-infection should be closely monitored following initiation of HAART...
  73. pmc An unusual cause of paraparesis in a patient on chronic steroid therapy
    R Gupta
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    J Spinal Cord Med 30:67-9. 2007
    ..Spinal epidural lipomatosis is the excessive deposition of unencapsulated fat in the epidural space. This is a rare disorder often associated with high levels of endogenous steroids or the administration of exogenous steroids...
  74. ncbi request reprint Overview and implications of obstructive sleep apnoea
    Hanish Sharma
    Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Chest Dis Allied Sci 50:137-50. 2008
    ..It is hoped that their appropriate use to increase patients' compliance may improve the quality of life as well as provide a survival benefit...
  75. ncbi request reprint Unusual lung mass: benign or malignant?
    Kiran Kumar
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Chest Dis Allied Sci 50:365-7. 2008
    ..Average time that elapses before diagnosis is reported to be two years. We report the case of a patient who remained well inspite of harbouring primary adenoid cystic carcinoma of lung for 15 years...
  76. ncbi request reprint Continuing medical education on antiretroviral therapy in HIV/AIDS in India: needs assessment and impact on clinicians and allied health personnel
    S K Kabra
    Department of Paediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
    Natl Med J India 22:257-60. 2009
    ..Over a 2-year period, 2005-2007, 3 CME programmes for ART were conducted for physicians and a fourth (predominantly) for paediatricians...
  77. pmc Retrospective study of chikungunya outbreak in urban areas of India
    B N Nagpal
    National Institute of Malaria Research, ICMR, New Delhi, India
    Indian J Med Res 135:351-8. 2012
    ..A retrospective study on chikungunya outbreak in India in five States viz. Delhi, Madhya Pradesh, Orissa, Maharashtra and Kerala was conducted in 2007-2008 to know the distribution and determinants of chikungunya fever outbreak in India...
  78. ncbi request reprint Effect of antituberculosis treatment on cardiopulmonary responses to exercise in miliary tuberculosis
    S K Sharma
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 124:411-8. 2006
    ..Tuberculosis (TB) is a major health problem in the developing world. In this preliminary study, we report the effect of antituberculosis treatment (ATT) on cardiopulmonary responses to exercise in patients with miliary tuberculosis (MTB)...
  79. doi request reprint High concentration of adenosine in human visceral leishmaniasis despite increased ADA and decreased CD73
    A K Rai
    Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, New Delhi, India
    Parasite Immunol 33:632-6. 2011
    ..These are less studied in infections like VL but are very important in terms of endogenous regulation of immune response among patients...
  80. pmc Assessment of effects on health due to consumption of bitter bottle gourd (Lagenaria siceraria) juice
    S K Sharma
    Indian Council of Medical Research, New Delhi, India
    Indian J Med Res 135:49-55. 2012
    ....
  81. doi request reprint Arterolane maleate plus piperaquine phosphate for treatment of uncomplicated Plasmodium falciparum malaria: a comparative, multicenter, randomized clinical trial
    Neena Valecha
    National Institute of Malaria Research, New Delhi, India
    Clin Infect Dis 55:663-71. 2012
    ..falciparum malaria...
  82. ncbi request reprint Progress of DOTS in global tuberculosis control
    S K Sharma
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
    Lancet 367:951-2. 2006
  83. doi request reprint Safety evaluation of an Ayurvedic medicine, Arogyavardhini vati on brain, liver and kidney in rats
    Gajendra Kumar
    Heavy Metal Toxicology Laboratory, Department of Pharmacology, All India Institute of Medical Sciences, New Delhi 110029, India
    J Ethnopharmacol 140:151-60. 2012
    ..However, toxicity due to the presence of heavy metals in this traditional medicine is a matter of concern...