Bhupesh Sharma

Summary

Publications

  1. doi request reprint Pharmacological inhibition of inducible nitric oxide synthase (iNOS) and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, convalesce behavior and biochemistry of hypertension induced vascular dementia in rats
    Bhupesh Sharma
    CNS and CVS Research Lab, Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, Patiala 147002, Punjab, India
    Pharmacol Biochem Behav 103:821-30. 2013
  2. doi request reprint Salutary effect of NFκB inhibitor and folacin in hyperhomocysteinemia-hyperlipidemia induced vascular dementia
    Bhupesh Sharma
    CNS and CVS Research Lab, Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, Patiala, 147002, Punjab, India
    Prog Neuropsychopharmacol Biol Psychiatry 38:207-15. 2012
  3. doi request reprint Defensive effect of natrium diethyldithiocarbamate trihydrate (NDDCT) and lisinopril in DOCA-salt hypertension-induced vascular dementia in rats
    Bhupesh Sharma
    Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, Patiala, 147002 Punjab, India
    Psychopharmacology (Berl) 223:307-17. 2012
  4. doi request reprint Experimental hypertension induced vascular dementia: pharmacological, biochemical and behavioral recuperation by angiotensin receptor blocker and acetylcholinesterase inhibitor
    Bhupesh Sharma
    CNS and CVS lab, Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, Patiala 147002, Punjab, India
    Pharmacol Biochem Behav 102:101-8. 2012
  5. pmc Ameliorative role of Atorvastatin and Pitavastatin in L-Methionine induced vascular dementia in rats
    Rajeshkumar U Koladiya
    Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, Patiala 147002, India
    BMC Pharmacol 8:14. 2008
  6. doi request reprint Behavioral and biochemical investigations to explore pharmacological potential of PPAR-gamma agonists in vascular dementia of diabetic rats
    Bhupesh Sharma
    Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, Patiala 147002, Punjab, India
    Pharmacol Biochem Behav 100:320-9. 2011
  7. doi request reprint Attenuation of vascular dementia by sodium butyrate in streptozotocin diabetic rats
    Bhupesh Sharma
    Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, Patiala, 147002, Punjab, India
    Psychopharmacology (Berl) 215:677-87. 2011
  8. doi request reprint Exploitation of HIV protease inhibitor Indinavir as a memory restorative agent in experimental dementia
    Bhupesh Sharma
    Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala Punjab, India
    Pharmacol Biochem Behav 89:535-45. 2008
  9. doi request reprint Modulation of celecoxib- and streptozotocin-induced experimental dementia of Alzheimer's disease by pitavastatin and donepezil
    Bhupesh Sharma
    Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab, India
    J Psychopharmacol 22:162-71. 2008
  10. ncbi request reprint Pitavastatin and 4'-hydroxy-3'-methoxyacetophenone (HMAP) reduce cognitive dysfunction in vascular dementia during experimental diabetes
    Bhupesh Sharma
    Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, Patiala, Punjab, India
    Curr Neurovasc Res 7:180-91. 2010

Collaborators

  • Nirmal Singh
  • Birdavinder Singh
  • Amteshwar S Jaggi
  • Rajeshkumar U Koladiya

Detail Information

Publications11

  1. doi request reprint Pharmacological inhibition of inducible nitric oxide synthase (iNOS) and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, convalesce behavior and biochemistry of hypertension induced vascular dementia in rats
    Bhupesh Sharma
    CNS and CVS Research Lab, Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, Patiala 147002, Punjab, India
    Pharmacol Biochem Behav 103:821-30. 2013
    ..It may be concluded that AG, an iNOS inhibitor and HMAP, a NADPH-oxidase inhibitor may be considered as potential agents for the management of Hypt induced VaD...
  2. doi request reprint Salutary effect of NFκB inhibitor and folacin in hyperhomocysteinemia-hyperlipidemia induced vascular dementia
    Bhupesh Sharma
    CNS and CVS Research Lab, Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, Patiala, 147002, Punjab, India
    Prog Neuropsychopharmacol Biol Psychiatry 38:207-15. 2012
    ..l-methionine induced HHcy-HL has caused VaD development in rats. NFκ-B inhibitors and folacin may be considered as potential agents for the management of HHcy-HL induced VaD...
  3. doi request reprint Defensive effect of natrium diethyldithiocarbamate trihydrate (NDDCT) and lisinopril in DOCA-salt hypertension-induced vascular dementia in rats
    Bhupesh Sharma
    Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, Patiala, 147002 Punjab, India
    Psychopharmacology (Berl) 223:307-17. 2012
    ..Tremendous amount of research work is required so that new pharmacological agents may be identified for their appropriate therapeutic utility to combat different dementing disorders...
  4. doi request reprint Experimental hypertension induced vascular dementia: pharmacological, biochemical and behavioral recuperation by angiotensin receptor blocker and acetylcholinesterase inhibitor
    Bhupesh Sharma
    CNS and CVS lab, Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, Patiala 147002, Punjab, India
    Pharmacol Biochem Behav 102:101-8. 2012
    ..It may be concluded that DOCA-salt hypertension induces VaD in rats. ARBs and AChEIs may be considered as potential pharmacological agents for the management of hypertension induced VaD...
  5. pmc Ameliorative role of Atorvastatin and Pitavastatin in L-Methionine induced vascular dementia in rats
    Rajeshkumar U Koladiya
    Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, Patiala 147002, India
    BMC Pharmacol 8:14. 2008
    ..In this study L-Methionine induced vascular dementia was assessed by Morris water-maze (MWM) test. Biochemical analysis was also performed to unfold possible mechanism of statins mediated modulation of vascular dementia...
  6. doi request reprint Behavioral and biochemical investigations to explore pharmacological potential of PPAR-gamma agonists in vascular dementia of diabetic rats
    Bhupesh Sharma
    Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, Patiala 147002, Punjab, India
    Pharmacol Biochem Behav 100:320-9. 2011
    ..It is concluded that PPAR-γ modulators pioglitazone and rosiglitazone may be considered as potential pharmacological agents for the management of diabetes induced VaD...
  7. doi request reprint Attenuation of vascular dementia by sodium butyrate in streptozotocin diabetic rats
    Bhupesh Sharma
    Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, Patiala, 147002, Punjab, India
    Psychopharmacology (Berl) 215:677-87. 2011
    ..At this point of time, it is very important to find the possible pharmacological agents which may be useful in management and therapy of dementia including Alzheimer's disease, vascular dementia, etc...
  8. doi request reprint Exploitation of HIV protease inhibitor Indinavir as a memory restorative agent in experimental dementia
    Bhupesh Sharma
    Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala Punjab, India
    Pharmacol Biochem Behav 89:535-45. 2008
    ..Study highlights the potential of Indinavir in memory dysfunctions associated with dementia of AD...
  9. doi request reprint Modulation of celecoxib- and streptozotocin-induced experimental dementia of Alzheimer's disease by pitavastatin and donepezil
    Bhupesh Sharma
    Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab, India
    J Psychopharmacol 22:162-71. 2008
    ..Reversal of Celecoxib/STZ induced memory deficits by Pitavastatin may be due to its antioxidative, anti beta amyloid aggregatory property, and by Donepezil, due to its anticholinesterase and neuroprotective actions...
  10. ncbi request reprint Pitavastatin and 4'-hydroxy-3'-methoxyacetophenone (HMAP) reduce cognitive dysfunction in vascular dementia during experimental diabetes
    Bhupesh Sharma
    Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, Patiala, Punjab, India
    Curr Neurovasc Res 7:180-91. 2010
    ..It may be concluded that STZ induces vascular dementia. 4'hydroxy-3'-methoxy acetophenone and Pitavastatin may be considered as potential pharmacological agents for the management of diabetes induced vascular dementia...
  11. doi request reprint Attenuating effect of lisinopril and telmisartan in intracerebroventricular streptozotocin induced experimental dementia of Alzheimer's disease type: possible involvement of PPAR-γ agonistic property
    Birdavinder Singh
    Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, India
    J Renin Angiotensin Aldosterone Syst 14:124-36. 2013
    ..c.v. STZ treated animals. The results of this investigation document a potential role of PPAR-γ in the beneficial effects of lisinopril and telmisartan in i.c.v. STZ dementia of AD type...