Lali Shanshiashvili


Affiliation: Ilia State University
Location: Tbilisi, Georgia
1. 1998–2005 Co-investigator in the Georgian Academy of Sciences N1510 grant.
2. 1999–2002 Co-investigator in INTAS-Georgia 97-1561 grant.
3. 2002-2004 Co-investigator in ISTC G- 617 grant.
4. 2002-2004 Co-investigator in ISTC G- 564 grant
5. 2002-2006 Co-investigator in INTAS 2001-0666 grant.
6. 2009-2011 Co-investigator in GNSF grant N376.
7. 2010-2011 Co-investigator in STCU grant N 5048

1.Adhesive Properties and Inflammatory Potential of Citrullinated Myelin Basic Protein Peptide 45-89. 2012 L.V.Shanshiashvili, Kalandadze IV, Ramsden JJ, Mikeladze DG. Neurochem Res.37(9):1959-66.
2.mGluR1 interacts with cystic fibrosis transmembrane conductance regulator and modulates the secretion of IL-10 in cystic fibrosis peripheral lymphocytes. 2012. L.V. Shanshiashvili, N. Dabrundashvili, N. Natsvlishvili, E. Kvaratskhelia, E. Zhuravliova, T. Barbakadze, S. Koriauli, E. Maisuradze, T. Topuria, D.G. Mikeladze Mol Immunol. Jul;51(3-4):310-5. ELSEVIER
3. Synaptic and Non-Synaptic Mitochondria in Hippocampus of Adult Rats Differ in Their Sensitivity to Hypothyroidism. 2012. Zhuravliova E, Barbakadze T, Jojua N, Zaalishvili E, Shanshiashvili L, Natsvlishvili N, Kalandadze I, Narmania N, Chogovadze I, Mikeladze D.Cell Mol Neurobiol. Jun 17. [Epub ahead of print] DOI 10.1007/s10571-012-9857-8. Springer
4.S-Nitrosylation Decreases the Adsorption of H-Ras in Lipid Bilayer and Changes Intrinsic Catalytic Activity. 2011. Shanshiashvili L, Narmania N, Barbakadze T, Zhuravliova E, Natsvlishvili N, Ramsden J, Mikeladze DG.Cell Biochem Biophys. 59, 191-199
5.Adhesion and clustering of charge isomers of myelin basic protein at model myelin membranes 2003.Shanshiashvili L., Suknidze N., Machaidze G., Mikeladze D., Ramsden J.Archives of Biochemistry and Biophysics. 419, 170-177 , Elsevier


  1. request reprint
    Shanshiashvili L, Suknidze N, Machaidze G, Mikeladze D, Ramsden J. Adhesion and clustering of charge isomers of myelin basic protein at model myelin membranes. Arch Biochem Biophys. 2003;419:170-7 pubmed
    ..Implications of these results for neurological disorders involving demyelination, such as multiple sclerosis, are discussed. ..
  2. Shanshiashvili L, Tsitsilashvili E, Dabrundashvili N, Kalandadze I, Mikeladze D. Metabotropic glutamate receptor 5 may be involved in macrophage plasticity. Biol Res. 2017;50:4 pubmed publisher
    ..We propose that elevation of intracellular glutamate and expression of mGluR5 may initiate the metabolic rearrangement in macrophages that could contribute to the formation of an immunosuppressive phenotype. ..

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