A G Shaikh

Summary

Publications

  1. Shaikh A, Wilmot G. Opsoclonus in a patient with increased titers of anti-GAD antibody provides proof for the conductance-based model of saccadic oscillations. J Neurol Sci. 2016;362:169-73 pubmed publisher
    ..We propose that opsoclonus might be due to increased levels of glutamate and subsequent hyperexcitability of excitatory and inhibitory burst neurons leading to reverberation in their reciprocally innervating circuit. ..
  2. Shaikh A, Wong A, Optican L, Zee D. Impaired Motor Learning in a Disorder of the Inferior Olive: Is the Cerebellum Confused?. Cerebellum. 2017;16:158-167 pubmed publisher
    ....
  3. Shaikh A, Zee D, Crawford J, Jinnah H. Cervical dystonia: a neural integrator disorder. Brain. 2016;139:2590-2599 pubmed
    ..We hypothesize that changing the activity in an impaired head neural integrator, by modulating feedback, could treat dystonia. ..
  4. Shaikh A, Straumann D, Palla A. Motion Illusion-Evidence towards Human Vestibulo-Thalamic Projections. Cerebellum. 2017;16:656-663 pubmed publisher
    ....
  5. Shaikh A, Zee D. Eye Movement Research in the Twenty-First Century-a Window to the Brain, Mind, and More. Cerebellum. 2017;: pubmed publisher
    ..The evaluation and treatment of patients with cerebellar ataxia are particularly amenable to such an approach. ..
  6. Shaikh A, Marti S, Tarnutzer A, Palla A, Crawford T, Straumann D, et al. Ataxia telangiectasia: a "disease model" to understand the cerebellar control of vestibular reflexes. J Neurophysiol. 2011;105:3034-41 pubmed publisher
    ..It may also be of value to the design of treatment trials as a surrogate biomarker of cerebellar function that does not require controlling for motivation or occult changes in motor strategy on the part of experimental subjects...
  7. Shaikh A, Termsarasab P, Nwankwo C, Rao Frisch A, Katirji B. Atypical forms of Guillain-Barré syndrome and H1N1-influenza vaccination. Vaccine. 2012;30:3251-4 pubmed publisher
    ..However, epidemiological studies with large cohorts are necessary to confirm excess cases of atypical GBS after H1N1-influenza vaccination. ..
  8. Shaikh A, Solomon D. Effects of Sustained Otolith-Only Stimulation on Post-Rotational Nystagmus. Cerebellum. 2017;16:683-690 pubmed publisher
    ..In post-rotational phase, the pure otolith signal affects vestibular ocular reflex gain matrix but does not affect the time constant. ..
  9. Shaikh A. Tremor analysis separates Parkinson's disease and dopamine receptor blockers induced parkinsonism. Neurol Sci. 2017;38:855-863 pubmed publisher
    ..Quantitative tremor analysis can distinguish Parkinson's disease from dopamine receptor blocking agent-induced parkinsonism. ..
  10. Kang S, Shaikh A. Acquired pendular nystagmus. J Neurol Sci. 2017;375:8-17 pubmed publisher
    ..Subsequent discussion of the pathophysiology of individual forms of pendular nystagmus speculates on mechanisms of the underlying disease while providing insights into pharmacotherapy of nystagmus. ..

Detail Information

Publications11

  1. Shaikh A, Wilmot G. Opsoclonus in a patient with increased titers of anti-GAD antibody provides proof for the conductance-based model of saccadic oscillations. J Neurol Sci. 2016;362:169-73 pubmed publisher
    ..We propose that opsoclonus might be due to increased levels of glutamate and subsequent hyperexcitability of excitatory and inhibitory burst neurons leading to reverberation in their reciprocally innervating circuit. ..
  2. Shaikh A, Wong A, Optican L, Zee D. Impaired Motor Learning in a Disorder of the Inferior Olive: Is the Cerebellum Confused?. Cerebellum. 2017;16:158-167 pubmed publisher
    ....
  3. Shaikh A, Zee D, Crawford J, Jinnah H. Cervical dystonia: a neural integrator disorder. Brain. 2016;139:2590-2599 pubmed
    ..We hypothesize that changing the activity in an impaired head neural integrator, by modulating feedback, could treat dystonia. ..
  4. Shaikh A, Straumann D, Palla A. Motion Illusion-Evidence towards Human Vestibulo-Thalamic Projections. Cerebellum. 2017;16:656-663 pubmed publisher
    ....
  5. Shaikh A, Zee D. Eye Movement Research in the Twenty-First Century-a Window to the Brain, Mind, and More. Cerebellum. 2017;: pubmed publisher
    ..The evaluation and treatment of patients with cerebellar ataxia are particularly amenable to such an approach. ..
  6. Shaikh A, Marti S, Tarnutzer A, Palla A, Crawford T, Straumann D, et al. Ataxia telangiectasia: a "disease model" to understand the cerebellar control of vestibular reflexes. J Neurophysiol. 2011;105:3034-41 pubmed publisher
    ..It may also be of value to the design of treatment trials as a surrogate biomarker of cerebellar function that does not require controlling for motivation or occult changes in motor strategy on the part of experimental subjects...
  7. Shaikh A, Termsarasab P, Nwankwo C, Rao Frisch A, Katirji B. Atypical forms of Guillain-Barré syndrome and H1N1-influenza vaccination. Vaccine. 2012;30:3251-4 pubmed publisher
    ..However, epidemiological studies with large cohorts are necessary to confirm excess cases of atypical GBS after H1N1-influenza vaccination. ..
  8. Shaikh A, Solomon D. Effects of Sustained Otolith-Only Stimulation on Post-Rotational Nystagmus. Cerebellum. 2017;16:683-690 pubmed publisher
    ..In post-rotational phase, the pure otolith signal affects vestibular ocular reflex gain matrix but does not affect the time constant. ..
  9. Shaikh A. Tremor analysis separates Parkinson's disease and dopamine receptor blockers induced parkinsonism. Neurol Sci. 2017;38:855-863 pubmed publisher
    ..Quantitative tremor analysis can distinguish Parkinson's disease from dopamine receptor blocking agent-induced parkinsonism. ..
  10. Kang S, Shaikh A. Acquired pendular nystagmus. J Neurol Sci. 2017;375:8-17 pubmed publisher
    ..Subsequent discussion of the pathophysiology of individual forms of pendular nystagmus speculates on mechanisms of the underlying disease while providing insights into pharmacotherapy of nystagmus. ..
  11. Shaikh A, Finkelstein S, Schuchard R, Ross G, Juncos J. Fixational eye movements in Tourette syndrome. Neurol Sci. 2017;38:1977-1984 pubmed publisher
    ..Possible clinical implication for these results is that fixational eye movements can be objective biological markers of TS. ..