Research Topics
Species | Sinisa RadulovicSummaryAffiliation: Institute for Oncology and Radiology of Serbia Country: Serbia and Montenegro Publications
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Detail Information
Publications
Trans-platinum complexes as anticancer drugs: recent developments and future prospectsS Radulovic
Dept Drug Development, Institute for Oncology and Radiology of Serbia, Pasterova 14, Belgrade, 11000, Yugoslavia
Curr Med Chem 9:1611-8. 2002..Trans-platinum compounds, appear to follow different pattern of cell killing in comparison to cisplatin, thus giving a reason for optimism in their development as a new class of platinum-based antitumor drugs...
[Recommendations for treatment of individuals at risk for hereditary breast and ovarian carcinoma]Sinisa Radulovic
Institute for Oncology and Radiology of Serbia, Belgrade
Srp Arh Celok Lek 131:345-50. 2003..Genetic testing, which plays a role in defining risk, requires careful pre- and post-test counseling to discuss the limitations of testing itself and available management strategies...
Sunitinib, sorafenib and mTOR inhibitors in renal cancerSinisa Radulovic
Department of Translational Research, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia
J BUON 12:S151-62. 2007..The development of these targeted therapies represents an exciting step forward in the treatment of advanced RCC...
Synthesis, structure and characterization of novel Cd(II) and Zn(II) complexes with the condensation product of 2-formylpyridine and selenosemicarbazide Antiproliferative activity of the synthesized complexes and related selenosemicarbazone complexesSnezana Bjelogrlić
Institute for Oncology and Radiology of Serbia, Department of Experimental Oncology, Laboratory for Experimental Pharmacology, Pasterova 14, Belgrade, Serbia
J Inorg Biochem 104:673-82. 2010....
A comparative study of DNA binding and cell cycle phase perturbation by the dinuclear complex of Cd(II) with the condensation product of 2-acetylpyridine and malonic acid dihydrazide N',N'(2) -bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazideMiroslava Vujcic
Department of Chemistry, Institute of Chemistry, Technology and Metallurgy, Belgrade, Serbia
J Biochem Mol Toxicol 25:175-82. 2011..Immunoblotting analysis showed the overexpression of Bcl-2 protein with the Cd(II)H(2) L complex...
Non-substituted N-heteroaromatic selenosemicarbazone metal complexes induce apoptosis in cancer cells via activation of mitochondrial pathwayTatjana Srdic-Rajic
Department of Experimental Oncology, Laboratory for Experimental Pharmacology, Institute for Oncology and Radiology of Serbia, National Cancer Research Center, Pasterova 14, 11 000 Belgrade, Serbia
Eur J Med Chem 46:3734-47. 2011....
Picolinate ruthenium(II)-arene complex with in vitro antiproliferative and antimetastatic properties: comparison to a series of ruthenium(II)-arene complexes with similar structureNevenka Gligorijević
Institute for Oncology and Radiology of Serbia, Belgrade, Serbia
J Inorg Biochem 108:53-61. 2012....
Molecular targeting agents in renal cell carcinoma: present strategies and future perspectivesSnezana K Bjelogrlic
Institute for Oncology and Radiology of Serbia, Pasterova 14, 11 000 Belgrade, Serbia
Curr Pharm Des 14:1058-77. 2008..This article overviews current knowledge in RCC molecular pathology with recent clinical data, and discuss present strategies for future development of targeted therapies...
Novel BRCA1/2 mutations in Serbian breast and breast-ovarian cancer patients with hereditary predispositionJelena Dobricić
Department of Experimental Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia
Cancer Genet Cytogenet 202:27-32. 2010..Steroid receptor-positive BRCA-related breast cancer in this proband supports the idea of characteristic pathological features and older age of onset among BRCA1-mutated ER-positive breast cancers...
IL-2-mediated augmentation of NK-cell activity and activation antigen expression on NK- and T-cell subsets in patients with metastatic melanoma treated with interferon-alpha and DTICGordana Konjevic
Department of Experimental Immunology, Institute for Oncology and Radiology of Serbia, Belgrade, Yugoslavia
Clin Exp Metastasis 20:647-55. 2003....
Association between methylenetetrahydrofolate reductase polymorphism C677T and risk of chronic myeloid leukemia in Serbian populationKsenija Jakovljević
Department of Experimental Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia
Leuk Lymphoma 53:1327-30. 2012..Our findings suggest that MTHFR 677 gene variants have no significant influence on the susceptibility to CML in a Serbian population...
Anti-metastatic and anti-angiogenic properties of potential new anti-cancer drugs based on metal complexes of selenosemicarbazonesManja Zec
National Cancer Research Center, Department of Experimental Pharmacology, Serbia
Anticancer Agents Med Chem 12:1071-80. 2012..In addition, they could modulate metastatic phenotype of tumor cells. Nickel (II) complex with 2-formylpyridine selenosemicarbazone revealed to be the most potent...
Synthesis and characterization of new Pt(II) and Pd(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone: cytotoxic activity evaluation of Cd(II), Zn(II), Ni(II), Pt(II) and Pd(II) complexes with heteroaromatic selenosemicarbazonesNevenka Gligorijević
Laboratory for Experimental Pharmacology, Institute for Oncology and Radiology of Serbia, 11000 Belgrade, Serbia
Eur J Med Chem 44:1623-9. 2009..The investigation of potential of these compounds to induce HeLa cell cycle perturbations was also evaluated...
Detection of DNA mutations based on analysis of multiple wavelength excitation/emission fluorescence kinetics curves in real-time PCRKatarina K Jovanović
Institute for Oncology and Radiology of Serbia, Department of Experimental Oncology, Pasterova 14, Belgrade, Serbia
Med Hypotheses 80:376-9. 2013..Method can be applied to any kit, capable to simultaneously detect several different mutations...
Severe skin toxicity observed with the combination of capecitabine and weekly paclitaxel in metastatic breast cancer patientsSnezana Susnjar
Department for Medical Oncology, Institute for Oncology and Radiology of Serbia, Pasterova 14, 11000, Belgrade, Serbia
Support Care Cancer 16:1415-8. 2008..DISCUSSION: We report severe skin toxicity observed in anthracycline-pretreated metastatic breast cancer patients receiving the combination of capecitabine and weekly paclitaxel...
Effects of dexrazoxane and amifostine on evolution of Doxorubicin cardiomyopathy in vivoSnezana K Bjelogrlic
Department of Experimental Oncology, Institute for Oncology and Radiology of Serbia, Pasterova 14, Belgrade, Serbia
Exp Biol Med (Maywood) 232:1414-24. 2007..Dexrazoxane has proved to be successful and superior over amifostine against such an evolution of doxorubicin cardiomyopathy...
cDNA microarrays: identification of gene signatures and their application in clinical practiceZvonko Magic
Institute for Medical Research, Military Medical Academy, Belgrade, Serbia
J BUON 12:S39-44. 2007..Gene expression profiles will also help clinicians make decisions about the optimal treatment of cancer patients...
