Aylin Sepici-Dincel

Summary

Publications

  1. doi request reprint Genotoxicity assessment of carp (Cyprinus carpio L.) fingerlings by tissue DNA damage and micronucleus test, after environmental exposure to fenitrothion
    Aylin Sepici-Dincel
    Faculty of Medicine, University of Gazi, Ankara, Turkey
    Toxicol Mech Methods 21:388-92. 2011
  2. ncbi request reprint Effects of in vivo antioxidant enzyme activities of myrtle oil in normoglycaemic and alloxan diabetic rabbits
    Aylin Sepici-Dincel
    Department of Medical Biochemistry, Gazi University, Besevler, Ankara 6510, Turkey
    J Ethnopharmacol 110:498-503. 2007
  3. ncbi request reprint Antioxidant enzymes and diabetic retinopathy
    Zuhal Yildirim
    Department of Medical Biochemistry, Faculty of Medicine, Gazi University, 06510 Besevler, Ankara, Turkey
    Ann N Y Acad Sci 1100:199-206. 2007
  4. doi request reprint Sublethal cyfluthrin toxicity to carp (Cyprinus carpio L.) fingerlings: biochemical, hematological, histopathological alterations
    Aylin Sepici-Dincel
    Department of Medical Biochemistry, Faculty of Medicine, Gazi University, Ankara, Turkey
    Ecotoxicol Environ Saf 72:1433-9. 2009
  5. doi request reprint Oxidative DNA damage: the thyroid hormone-mediated effects of insulin on liver tissue
    Nilgun Altan
    Department of Medical Biochemistry, Faculty of Medicine, Gazi University, Ankara, Turkey
    Endocrine 38:214-20. 2010
  6. doi request reprint Sublethal propoxur toxicity to juvenile common carp (Cyprinus carpio L., 1758): biochemical, hematological, histopathological, and genotoxicity effects
    Ali Gul
    Department of Biology Education, Gazi University, Teknikokullar, Ankara, Turkey
    Environ Toxicol Chem 31:2085-92. 2012
  7. ncbi request reprint Pseudoexfoliation syndrome and trace elements
    Zuhal Yildirim
    Gazi University, Faculty of Medicine, Department of Medical Biochemistry, 06510 Besevler, Ankara, Turkey
    Ann N Y Acad Sci 1100:207-12. 2007
  8. doi request reprint The acute toxicity of fenitrothion on narrow-clawed crayfish (Astacus leptodactylus Eschscholtz, 1823) in association with biomarkers of lipid peroxidation
    Rabia Sarikaya
    Department of Primary School Education, Gazi University, Teknikokullar, Ankara, Turkey
    J Biochem Mol Toxicol 25:169-74. 2011
  9. doi request reprint Oxidative stress-induced endothelial cell damage in thyroidectomized rat
    Ayse Basak Engin
    Gazi University, Department of Toxicology, TR 06330 Hipodrom, Ankara, Turkey
    Exp Toxicol Pathol 64:481-5. 2012
  10. doi request reprint A quantitative evaluation of total antioxidant status and oxidative stress markers in preeclampsia and gestational diabetic patients in 24-36 weeks of gestation
    Ozlem Karacay
    Department of Obstetrics and Gynecology, Ankara Etlik Maternity and Women s Health Teaching and Research Hospital, Ankara, Turkey
    Diabetes Res Clin Pract 89:231-8. 2010

Collaborators

Detail Information

Publications20

  1. doi request reprint Genotoxicity assessment of carp (Cyprinus carpio L.) fingerlings by tissue DNA damage and micronucleus test, after environmental exposure to fenitrothion
    Aylin Sepici-Dincel
    Faculty of Medicine, University of Gazi, Ankara, Turkey
    Toxicol Mech Methods 21:388-92. 2011
    ..Such biomarkers may be used in assessing adverse/toxic effects of pesticides as environmental stressors...
  2. ncbi request reprint Effects of in vivo antioxidant enzyme activities of myrtle oil in normoglycaemic and alloxan diabetic rabbits
    Aylin Sepici-Dincel
    Department of Medical Biochemistry, Gazi University, Besevler, Ankara 6510, Turkey
    J Ethnopharmacol 110:498-503. 2007
    ..There is a very limited knowledge about MO and its effects on diabetes. Therefore, we tried to explain the mechanism that might underlie the protective effects of MO with this paper...
  3. ncbi request reprint Antioxidant enzymes and diabetic retinopathy
    Zuhal Yildirim
    Department of Medical Biochemistry, Faculty of Medicine, Gazi University, 06510 Besevler, Ankara, Turkey
    Ann N Y Acad Sci 1100:199-206. 2007
    ..AOPP levels were statistically increased in group 1 compared to control group. It can be suggested that hyperglycemia in DM is associated with accelerated nonenzymatic glycation and oxidative stress...
  4. doi request reprint Sublethal cyfluthrin toxicity to carp (Cyprinus carpio L.) fingerlings: biochemical, hematological, histopathological alterations
    Aylin Sepici-Dincel
    Department of Medical Biochemistry, Faculty of Medicine, Gazi University, Ankara, Turkey
    Ecotoxicol Environ Saf 72:1433-9. 2009
    ..Potential oxidative-stress-inducing effect of synthetic pyrethroid cyfluthrin, as lipid peroxidation, in addition to its sodium channel blocking, is reported for the first time as an additional mechanism of action...
  5. doi request reprint Oxidative DNA damage: the thyroid hormone-mediated effects of insulin on liver tissue
    Nilgun Altan
    Department of Medical Biochemistry, Faculty of Medicine, Gazi University, Ankara, Turkey
    Endocrine 38:214-20. 2010
    ..Consequently, it was observed that the DNA and protein damage induced by oxidative stress in diabetes could be regulated by dose-dependent thyroid hormone-mediated effects to insulin treatment...
  6. doi request reprint Sublethal propoxur toxicity to juvenile common carp (Cyprinus carpio L., 1758): biochemical, hematological, histopathological, and genotoxicity effects
    Ali Gul
    Department of Biology Education, Gazi University, Teknikokullar, Ankara, Turkey
    Environ Toxicol Chem 31:2085-92. 2012
    ..01). Only plasma calcium and potassium levels decreased in the experimental group. Propoxur has an ecotoxicological potential on fish, a nontarget organism...
  7. ncbi request reprint Pseudoexfoliation syndrome and trace elements
    Zuhal Yildirim
    Gazi University, Faculty of Medicine, Department of Medical Biochemistry, 06510 Besevler, Ankara, Turkey
    Ann N Y Acad Sci 1100:207-12. 2007
    ..38-92.14 microg/g tissue) was not statistically different. The decreased content of zinc could increase oxidative stress. The results support the role of oxidative stress in the development of PSX in cataract patients...
  8. doi request reprint The acute toxicity of fenitrothion on narrow-clawed crayfish (Astacus leptodactylus Eschscholtz, 1823) in association with biomarkers of lipid peroxidation
    Rabia Sarikaya
    Department of Primary School Education, Gazi University, Teknikokullar, Ankara, Turkey
    J Biochem Mol Toxicol 25:169-74. 2011
    ..We can conclude that fenitrothion is highly toxic to crayfish, a nontarget organism in the ecosystem, and the lipid peroxidation indicators can be easily used for monitoring environmental effects...
  9. doi request reprint Oxidative stress-induced endothelial cell damage in thyroidectomized rat
    Ayse Basak Engin
    Gazi University, Department of Toxicology, TR 06330 Hipodrom, Ankara, Turkey
    Exp Toxicol Pathol 64:481-5. 2012
    ..It is concluded that hypothyroidism might lead to systemic oxidative stress with resultant endothelial dysfunction, and subsequent occurrence of atherosclerosis...
  10. doi request reprint A quantitative evaluation of total antioxidant status and oxidative stress markers in preeclampsia and gestational diabetic patients in 24-36 weeks of gestation
    Ozlem Karacay
    Department of Obstetrics and Gynecology, Ankara Etlik Maternity and Women s Health Teaching and Research Hospital, Ankara, Turkey
    Diabetes Res Clin Pract 89:231-8. 2010
    ....
  11. doi request reprint Tryptophan degradation and neopterin levels in treated rheumatoid arthritis patients
    Yesim Ozkan
    Department of Biochemistry, Faculty of Pharmacy, Gazi University, Etiler, Ankara, Turkey
    Clin Rheumatol 31:29-34. 2012
    ..524, p < 0.03). Determination of tryptophan degradation and neopterin levels in chronic inflammatory disease may provide a better understanding of progression of the disease...
  12. doi request reprint Does exercise affect the antioxidant system in patients with ankylosing spondylitis?
    Zafer Gunendi
    Department of Physical Medicine and Rehabilitation, Gazi University Faculty of Medicine, Besevler, Ankara, Turkey
    Clin Rheumatol 29:1143-7. 2010
    ..Short-term, supervised exercise program improved functional status and decreased disease activity. However, the mechanism of this beneficial clinical effect does not seem to be through antioxidant activity...
  13. ncbi request reprint The association between total antioxidant status and oxidative stress in Behçet's disease
    Aylin Sepici-Dincel
    Department of Medical Biochemistry, Faculty of Medicine, Gazi University, Ankara, Turkey
    Rheumatol Int 26:1005-9. 2006
    ..Our results suggest that there is an insufficient antioxidant system and increased oxidative status both in BD and RAS patients. The antioxidant supplementations in addition to medical treatments will improve the quality of life...
  14. ncbi request reprint How Sublethal Fenitrothion is Toxic in Carp (Cyprinus carpio L.) Fingerlings
    Aylin Sepici-Dincel
    Department of Medical Biochemistry, Faculty of Medicine, Gazi University, Ankara, Turkey, 06510
    Toxicol Mech Methods 17:489-95. 2007
    ..05). As a result, we can conclude that early life stages of fish are very susceptible to the adverse effects of toxicants...
  15. doi request reprint The thyroid hormone mediated effects of insulin on serum leptin levels of diabetic rats
    Funda Kosova
    Department of Medical Biochemistry, Faculty of Medicine, Gazi University, Ankara, Turkey
    Endocrine 33:317-22. 2008
    ....
  16. doi request reprint The effects of sulfonylurea glyburide on superoxide dismutase, catalase, and glutathione peroxidase activities in the brain tissue of streptozotocin-induced diabetic rat
    Namik K Nazaroglu
    Faculty of Medicine, Department of Medical Biochemistry, Gazi University, Besevler, Ankara, Turkey
    J Diabetes Complications 23:209-13. 2009
    ..However, experimental evidences have indicated that sulfonylureas have also had an extrapancreatic effect, which may directly contribute toward maintaining blood glucose homeostasis during diabetes...
  17. ncbi request reprint Uncomplicated type 1 diabetes is associated with increased asymmetric dimethylarginine concentrations
    Alev E Altinova
    Departments of Endocrinology and Metabolism, Gazi University Faculty of Medicine, Ahmet Rasim Sok 41 6, 06550 Cankaya, Ankara, Turkey
    J Clin Endocrinol Metab 92:1881-5. 2007
    ..Asymmetric dimethylarginine (ADMA) has recently emerged as an independent risk marker for cardiovascular disease, but studies investigating the ADMA levels in type 1 diabetes mellitus (DM) are scarce...
  18. pmc The role of the cytokines in the pathogenesis of pseudoexfoliation syndrome
    Zuhal Yildirim
    Etimesgut Public Health Laboratory, Etimesgut 06770, Ankara, Turkey
    Int J Ophthalmol 6:50-3. 2013
    ..To examine the mechanism of the development of pseudoexfoliation (PSX) syndrome via both cytokine formation and endothelial vasorelaxing and growth factors that will provide us new therapeutic insights for the treatment...
  19. ncbi request reprint Influence of surgical trauma on neopterin concentrations in gastric carcinoma patients
    Ayse Basak Engin
    Faculty of Pharmacy, Department of Toxicology, Gazi University, Besevler, Ankara, Turkey
    Tumori 96:589-93. 2010
    ..The present study was undertaken to evaluate the impact of major surgical trauma on host cellular immunity of gastric carcinoma cases...
  20. doi request reprint Quantum chemical investigation of nitrotyrosine (3-nitro-L-tyrosine) and 8-nitroguanine
    Sakir Erkoc
    Department of Physics, Middle East Technical University, 06531, Ankara, Turkey
    Amino Acids 38:319-27. 2010
    ..The geometry of the nitrotyrosine and 8-nitroguanine molecules have been optimized, the vibrational dynamics and the electronic properties calculated in their ground states in the gas phase...